dapsone has been researched along with mephenytoin in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Black, C; Branch, RA; Csuka, ME; Lupoli, S; May, G; Wilkinson, GR | 1 |
| Bellino, L; Black, CM; Branch, RA; Csuka, ME; May, DG; Olsen, NJ; Porter, JA; Tanner, SB; Wilkinson, GR | 1 |
| Clauw, DJ; Flockhart, DA; Hewett, J; Sale, EB; Woosley, RL | 1 |
| Chiba, K; Darmansjah, I; Ishizaki, T; Kusaka, M; Setiabudy, R | 1 |
| Branch, RA; May, DG; Porter, J; Wilkinson, GR | 1 |
| Caraco, Y; Wilkinson, GR; Wood, AJ | 1 |
| Adedoyin, A; Branch, RA; Frye, RF; Matzke, GR; Porter, JA | 1 |
| Adedoyin, A; Branch, RA; Frye, RF; Romkes, M; Wilson, JW | 1 |
| Branch, RA; Frye, RF | 1 |
| Branch, RA; Frye, RF; Romkes, M; Tracy, TS; Zgheib, NK | 1 |
1 review(s) available for dapsone and mephenytoin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for dapsone and mephenytoin
| Article | Year |
|---|---|
Differences between white subjects and Chinese subjects in the in vivo inhibition of cytochrome P450s 2C19, 2D6, and 3A by omeprazole.
Topics: Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; China; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Omeprazole; White People | 1996 |
Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes.
Topics: Adult; Analysis of Variance; Arylamine N-Acetyltransferase; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Interactions; Humans; Male; Mephenytoin; Phenotype; Reference Values | 1997 |
Validation of incorporating flurbiprofen into the Pittsburgh cocktail.
Topics: Administration, Oral; Adolescent; Adult; Aged; Caffeine; Chlorzoxazone; Cross-Over Studies; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Therapy, Combination; Female; Flurbiprofen; Genotype; Humans; Isoenzymes; Male; Mephenytoin; Middle Aged | 2006 |
11 other study(ies) available for dapsone and mephenytoin
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Activity of oxidative routes of metabolism of debrisoquin, mephenytoin, and dapsone is unrelated to the pathogenesis of vinyl chloride-induced disease.
Topics: Arylamine N-Acetyltransferase; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Humans; Male; Mephenytoin; Middle Aged; Occupational Diseases; Oxidation-Reduction; Phenotype; Regression Analysis; Vinyl Chloride | 1992 |
Scleroderma is associated with differences in individual routes of drug metabolism: a study with dapsone, debrisoquin, and mephenytoin.
Topics: Acetylation; Adult; Biotransformation; Dapsone; Debrisoquin; Disease Susceptibility; Female; Humans; Hydantoins; Hydroxylation; Isoquinolines; Logistic Models; London; Male; Mephenytoin; Middle Aged; Oxidation-Reduction; Scleroderma, Systemic; Tennessee | 1990 |
Pharmacogenetic characteristics of the eosinophilia-myalgia syndrome.
Topics: Alleles; Arylamine N-Acetyltransferase; Case-Control Studies; Dapsone; Debrisoquin; Eosinophilia-Myalgia Syndrome; Female; Genotype; Humans; Mephenytoin; Phenotype; Xenobiotics | 1994 |
Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: a cocktail and extended phenotyping assessment trial.
Topics: Acetylation; Adolescent; Adult; Asian People; China; Dapsone; Female; Humans; Hydroxylation; Indonesia; Japan; Male; Mephenytoin; Metoprolol; Middle Aged; Phenotype; Polymorphism, Genetic | 1994 |
Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population.
Topics: Acetylation; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Female; Humans; Hydroxylation; Male; Mephenytoin; Middle Aged; Mixed Function Oxygenases; Phenotype; Regression Analysis; White People | 1994 |
In vivo modulation of CYP enzymes by quinidine and rifampin.
Topics: Acetylation; Administration, Oral; Adrenergic alpha-Antagonists; Adult; Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Enzyme Inhibitors; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Quinidine; Reference Values; Rifampin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline | 2000 |
Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Disulfiram; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Male; Mephenytoin; Mixed Function Oxygenases; Time Factors | 2002 |