dapsone has been researched along with isoniazid in 107 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 82 (76.64) | 18.7374 |
1990's | 7 (6.54) | 18.2507 |
2000's | 5 (4.67) | 29.6817 |
2010's | 12 (11.21) | 24.3611 |
2020's | 1 (0.93) | 2.80 |
Authors | Studies |
---|---|
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Bera, S; Mondal, D | 1 |
Abbate, EH; Albareda, MA; Garay, C; González Montaner, LF | 1 |
Urbanczik, R | 4 |
Freerksen, E; Rosenfeld, M | 3 |
Sighart, H | 1 |
Fujuda, T; Hagiwara, S; Ishihara, S | 1 |
Gekle, D; Mingers, AM; Pfüller, H | 1 |
Freerksen, E | 2 |
Kittel, H | 1 |
Bergsmann, O; Spielmann, E | 1 |
Hoose, C | 2 |
Bonnici, E; Depasquale, G; Freerksen, E; Kriiger-Thiemer, M; Rosenfeld, M | 1 |
Blaha, HM | 1 |
Amadio, G; Chehín, E; Quinteros, CM; Ratner, M; Wayar, E | 1 |
Benkö, M; Opl, G | 2 |
Müller, W | 1 |
Orlowski, EH | 1 |
Havel, A; Rosenfeld, M | 1 |
Freeksen, E; Rosenfeld, M | 1 |
Papageogiou, A; Peters, M | 1 |
Pereira, V | 1 |
Iyer, GG; Ramu, G | 1 |
De Las Aguas, JT | 1 |
Terencio de las Aguas, J | 1 |
Alvarenga, AE; Innami, S; Leguizamón, OR | 1 |
Depasquale, G | 2 |
Hamzah, M; Kosasih, A | 1 |
Krenzien, HN | 1 |
Rohde, R | 1 |
Aschhoff, M | 1 |
Allen, BW; Ellard, GA; Gammon, PT; King, RC; McDougall, AC; Rees, RJ; Weddell, AG | 1 |
Eberhardt, K; Hartmann, W; Hoose, C; Wosniok, W | 1 |
Balakrishnan, A; Christian, M; Nagarajan, M; Prabhakar, R; Somasundaram, PR; Thomas, A; Tripathy, SP | 1 |
Aoyagi, T; Toyoda, T | 1 |
Mengistu, G; Warndorff van Diepen, T | 1 |
Ellard, GA; Pearson, JM; Stanley, JN | 2 |
Katoch, K; Ramanathan, U; Ramu, G | 2 |
Gharpuray, MB; Kulkarni, DS; Kulkarni, V | 1 |
Alvarenga, AE; Haubitz, I; Leguizamon, O; Pritze, S | 1 |
Felten, MK | 1 |
Felten, MK; van der Merwe, CA | 1 |
Baohong, J; Grosset, JH; Ito, T | 1 |
Ellard, GA; Kiran, KU; Stanley, JN | 1 |
Kleeberg, HH | 2 |
Leiker, DL | 1 |
Alvarenga, AE | 1 |
Dietrich, M; Wabitsch, R | 1 |
Chum, HJ | 1 |
Ganapati, R; Maniar, JK; Parikh, AC; Parikh, DA | 1 |
Cowie, RL; Langton, ME | 1 |
Piening, E; Schirren, C | 1 |
Wagner, WH | 1 |
Ellard, GA; Gammon, PT; Helmy, HS; Rees, RJ | 1 |
Pattyn, SR; Wagner, WH | 1 |
Gordon, GR; Peters, JH; Shafizadeh, AG | 1 |
Verhagen, AR | 1 |
Jackson, EA; McLeod, DC | 1 |
Rees, RJ | 1 |
Freerksen, E; Hokama, S; Rosenfeld, M | 1 |
Yeats, RO | 1 |
Levy, L; Peters, JH | 1 |
Skakun, NP | 1 |
Chaudhury, S; Ghosh, S; Hazra, S; Kundu, SK | 1 |
Ramu, G | 1 |
Pattyn, SR; Portaels, F; Van den Breen, L; Van Loo, G | 1 |
Boval, C; Grosset, J; Truffot, C | 1 |
Opl, G; Sighart, H; Weirich, H | 1 |
Ahmad, RA; Rogers, HJ; Vandenburg, M; Wright, P | 1 |
Hanson, A; Melander, A; Wåhlin-Boll, E | 1 |
Hanson, A; Leden, I; Melander, A; Sturfelt, G; Svensson, B; Wàhlin-Boll, E | 1 |
Bharadwaj, VP; Desikan, KV; Ramu, G; Venkatesan, K | 1 |
Novak, M; Opl, G | 1 |
Richardus, JH; Smith, TC | 1 |
Drever, W; van Brakel, WH | 1 |
Bender, J; Hill, KR; Hurtado, AM; Rosenblatt, W; Scharmen, T | 1 |
FLOCH, H; FLOCH, T | 1 |
Grossi, P; Kanter, Rd; Monaci, S; Monshouwer, M; Turlizzi, E; Vignati, L | 1 |
Gatt, P; Jacobson, RR | 1 |
Ali, MA; Govindasamy, J; Manogaran, E; Pandian, S; Sellappan, V | 1 |
Chew, R; Woods, ML | 1 |
5 review(s) available for dapsone and isoniazid
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
[New methods of experimental chemotherapy in leprosy].
Topics: Aminobenzoates; Animals; Culture Techniques; Dapsone; Ethambutol; Isoniazid; Leprosy; Mice; Mycobacterium leprae; Phenazines; Rats; Streptomycin; Thioacetazone | 1969 |
Recent advances in the study of the leprosy bacillus.
Topics: Animals; Cricetinae; Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprosy; Mice; Microbial Sensitivity Tests; Microscopy, Electron; Mycobacterium leprae | 1969 |
[Pharmacokinetics of drug preparations metabolized by N-acetyltransferase].
Topics: Acetylation; Acetyltransferases; Dapsone; Humans; Hydralazine; Inactivation, Metabolic; Isoniazid; Kinetics; Liver; Pharmaceutical Preparations; Phenotype; Procainamide; Sulfamethazine; Sulfasalazine | 1982 |
21 trial(s) available for dapsone and isoniazid
Article | Year |
---|---|
Experimental data on the antimicrobial activity of Isoprodian (PTH).
Topics: Antitubercular Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Isoniazid; Isonicotinic Acids; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prothionamide; Tuberculosis, Pulmonary | 1978 |
Clinical results obtained with Isoprodian in the treatment of new cases of pulmonary tuberculosis.
Topics: Antitubercular Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Prothionamide; Tuberculosis, Pulmonary | 1978 |
[Treatment of open cavernous pulmonary tuberculosis (author's transl)].
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Prothionamide; Rifampin; Tuberculosis, Pulmonary | 1979 |
[A preliminary report on the clinical efficacy of isoprodian (author's transl)].
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Humans; Isoniazid; Isonicotinic Acids; Male; Prothionamide; Tuberculosis, Pulmonary | 1976 |
[Isoniazio, prothionamide and diafenylsulphone (isoprodian) in the therapy of previously untreated pulmonary (author's transl)].
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Female; Humans; Isoniazid; Isonicotinic Acids; Male; Prothionamide; Tuberculosis, Pulmonary | 1976 |
[Clinical experience with isoprodian in the treatment of adult pulmonary tuberculosis (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Female; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Tuberculosis, Pulmonary | 1976 |
Treatment of leprosy with rifampicin and isoprodian (L73A).
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Prothionamide; Rifampin | 1975 |
Clinical and bacteriological effects of rifampicin in combination with L73A in leprosy: observation for six months.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Mycobacterium leprae; Prothionamide; Rifampin | 1975 |
Rifampicin and isoprodian in combination in the treatment of leprosy.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Malta; Prothionamide; Rifampin | 1975 |
Preliminary experience with rifampicin and isoprodian (L73A)--combination in lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Male; Middle Aged; Prothionamide; Rifampin | 1975 |
Preliminary experience with rifampicin and isoprodian in combination in leprosy treatment.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Middle Aged; Prothionamide; Rifampin | 1975 |
Report of combined therapy in leprosy with rifampicin and isoprodian conducted at the Bisidimo-center, Ethiopia.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethiopia; Female; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Prothionamide; Rifampin | 1975 |
Does isoniazid increase the hepatotoxicity of the combination prothionamide-dapsone? Isoprodian Study Group.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Dapsone; Double-Blind Method; Drug Combinations; Female; Humans; Incidence; Isoniazid; Leprostatic Agents; Leprosy, Lepromatous; Liver Function Tests; Male; Middle Aged; Prospective Studies; Prothionamide; Rifampin | 1992 |
Controlled clinical trial of two multidrug regimens with and without rifampin in highly bacilliferous BL/LL south Indian patients: a five-year report.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Isoniazid; Leprostatic Agents; Leprosy, Borderline; Leprosy, Lepromatous; Male; Randomized Controlled Trials as Topic; Rifampin | 1990 |
Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment.
Topics: Adolescent; Adult; Dapsone; Drug Combinations; Drug Resistance; Humans; Isoniazid; Leprosy; Recurrence; Rifampin; Sex Factors; Thioacetazone | 1985 |
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report.
Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Mice; Middle Aged; Muscle, Smooth; Pyrazinamide; Rifampin; Scrotum; Skin; Thioacetazone | 1988 |
Random variation in tuberculin sensitivity in schoolchildren. Serial skin testing before and after preventive treatment for tuberculosis.
Topics: Adolescent; Child; Dapsone; Drug Combinations; Ethambutol; Female; Humans; Hypersensitivity, Delayed; Isoniazid; Male; Placebos; Prothionamide; Random Allocation; Rifampin; Tuberculin Test; Tuberculosis, Pulmonary | 1989 |
Pulmonary tuberculosis treated with isoprodian and rifampicin or pyrazinamide.
Topics: Adult; Aged; Antitubercular Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Patient Compliance; Prothionamide; Pyrazinamide; Radiography; Recurrence; Rifampin; Sputum; Tuberculosis, Pulmonary | 1987 |
Tolerability and efficacy of isoprodian-containing antituberculosis regimens.
Topics: Adult; Antitubercular Agents; Child; Clinical Trials as Topic; Dapsone; Drug Combinations; Humans; Isoniazid; Isonicotinic Acids; Prothionamide; Tuberculosis, Pulmonary | 1986 |
Comparison of DDS with two combined chemotherapy regimens for multibacillary leprosy. Results after 3 years of treatment. A prospective randomized multicentre study.
Topics: Adult; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Prospective Studies; Prothionamide; Random Allocation; Rifampin | 1986 |
[Comparative study of the treatment of pulmonary tuberculosis with isoprodian and pyrazinamide as well as isoprodian and rifampicin].
Topics: Adult; Aged; Antitubercular Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Pyrazinamide; Radiography; Rifampin; Sputum; Time Factors; Tuberculosis, Pulmonary | 1982 |
81 other study(ies) available for dapsone and isoniazid
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Controlling the spread of leprosy--some observations on.
Topics: Allied Health Personnel; Antitubercular Agents; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Health Services; Humans; India; Isoniazid; Leprosy; Organization and Administration; Sulfones; Thioacetazone; Tuberculosis | 1976 |
[A new therapeutic approach to open pulmonary tuberculosis with a combination of isoniazid, prothionamid and dapson (author's transl)].
Topics: Adolescent; Adult; Dapsone; Drug Combinations; Drug Evaluation; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Mycobacterium tuberculosis; Prothionamide; Sputum; Tuberculosis, Pulmonary | 1978 |
Leprosy eradication project of Malta. First published report after 5 years running.
Topics: Adolescent; Adult; Aged; Bacteriological Techniques; Child; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Malta; Middle Aged; Prothionamide; Rifampin; Time Factors | 1977 |
In vitro resistance test of human leprosy bacilli to anti-leprous drugs.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprostatic Agents; Leprosy; Microbial Sensitivity Tests; Mycobacterium leprae; Rifampin; Streptomycin | 1977 |
[Treatment of children with tuberculosis using Isoprodian].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Dapsone; Drug Combinations; Drug Evaluation; Humans; Infant; Infant, Newborn; Isoniazid; Isonicotinic Acids; Prothionamide; Tuberculosis, Pulmonary | 1977 |
[Research in the campaign against leprosy (author's transl)].
Topics: Animals; Armadillos; Dapsone; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Mice; Models, Biological; Mycobacterium; Prothionamide; Rifampin | 1977 |
[Long-term treatment of tuberculosis with isoprodian (author's transl)].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Dapsone; Drug Combinations; Drug Evaluation; Drug Resistance, Microbial; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Sputum; Tuberculosis, Pulmonary | 1979 |
On the mechanism of the antimycobacterial activity of isoniazid + prothionamide + dapsone (Isoprodian).
Topics: Adsorption; Calcium; Cell Membrane Permeability; Dapsone; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Isoniazid; Isonicotinic Acids; Mutation; Mycobacteriophages; Mycobacterium; Potassium; Prothionamide; Sodium | 1979 |
[Successful chemotherapy of avian mycobacteriosis with isoprodian (author's transl)].
Topics: Adult; Cycloserine; Dapsone; Drug Combinations; Humans; Isoniazid; Isonicotinic Acids; Male; Mycobacterium avium; Prothionamide; Tuberculosis, Pulmonary | 1978 |
Combined therapy in leprosy. Background and findings.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Leprosy; Prothionamide; Rifampin | 1978 |
Clinical and epidemiological aspects of myocobacterial infection in Western Germany.
Topics: Adult; Aged; Airway Obstruction; Aspergillosis; Carrier State; Dapsone; Female; Germany, West; Humans; Infectious Mononucleosis; Isoniazid; Male; Middle Aged; Prothionamide; Spondylitis, Ankylosing; Tuberculosis | 1978 |
[Isoprodiane therapy for previously untreated cavitating pulmonary tuberculosis (author's transl)].
Topics: Adolescent; Adult; Dapsone; Drug Combinations; Drug Evaluation; Female; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Tuberculosis, Pulmonary | 1979 |
[In-vitro study of the effects of 4,4-diamino-diphenylsulphone in combination with isoniazid and rifampicin (author's transl)].
Topics: Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; In Vitro Techniques; Isoniazid; Mycobacterium leprae; Mycobacterium tuberculosis; Rifampin | 1975 |
[Treatment of new cases of pulmonary tuberculosis with a combination of isoprodian and ethambutol; clinical results (author's transl)].
Topics: Adult; Antitubercular Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Isonicotinic Acids; Male; Prothionamide; Time Factors; Tuberculosis, Pulmonary | 1977 |
[Advances in anti-tuberculosis therapy (author's transl)].
Topics: Antitubercular Agents; Dapsone; Drug Synergism; Humans; Isoniazid; Prothionamide; Tuberculosis, Pulmonary | 1976 |
[Haematological effects of isoprodian (author's transl)].
Topics: Adult; Aged; Blood; Blood Cell Count; Dapsone; Drug Combinations; Female; Hematocrit; Hemoglobinometry; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Tuberculosis, Pulmonary | 1976 |
[Haemoglobin levels during prolonged treatment with isoprodian, a combination of isoniazid, prothionamide and diaphenylsulphone (author's transl)].
Topics: Aged; Dapsone; Drug Combinations; Erythrocytes; Female; Hemoglobinometry; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide | 1976 |
[Treatment of severe open cavitary pulmonary tuberculosis with a combination of rifampicin and isoprodian (author's transl)].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Rifampin; Tuberculosis, Pulmonary | 1976 |
Side effects of clofazimine therapy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Female; Humans; Ichthyosis; Isoniazid; Leprosy; Male; Skin Pigmentation | 1976 |
[New drugs in the treatment of leprosy].
Topics: Dapsone; Drug Combinations; Drug Evaluation; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Prothionamide; Rifampin; Tablets | 1976 |
Preliminary experience with combined therapy using rifampicin and isoprodian (L73A).
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Prothionamide; Rifampin | 1975 |
Treatment of leprosy with rifampicin and isoprodian in 38 patients at St. Thomas Hospital, Chetput, Sout India.
Topics: Adolescent; Adult; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; India; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Middle Aged; Prothionamide; Rifampin | 1975 |
The penetration of dapsone, rifampicin, isoniazid and pyrazinamide into peripheral nerves.
Topics: Animals; Dapsone; Dogs; Isoniazid; Peripheral Nerves; Pyrazinamide; Rifampin; Sciatic Nerve; Sheep; Time Factors | 1975 |
[Short- and long-term results of tuberculosis therapy with a fixed combination of isoniazide, prothionamide and diaminodiphenylsulfone combined with rifampicin].
Topics: Dapsone; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Isonicotinic Acids; Long-Term Care; Male; Prothionamide; Rifampin; Tuberculosis, Pulmonary | 1990 |
[Drugs used in tuberculosis and leprosy].
Topics: Administration, Oral; Antibiotics, Antitubercular; Clofazimine; Dapsone; Humans; Injections, Intramuscular; Isoniazid; Leprostatic Agents; Leprosy; Rifampin; Streptomycin; Tuberculosis | 1990 |
Ethionamide, prothionamide and thiacetazone self-administration. Studies of patient compliance using isoniazid-marked formulations.
Topics: Adolescent; Adult; Aged; Dapsone; Drug Therapy, Combination; Ethionamide; Female; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Male; Middle Aged; Patient Compliance; Prothionamide; Self Administration; Thioacetazone | 1986 |
Multiple cold abscesses in a borderline lepromatous patient on multidrug therapy.
Topics: Abscess; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Ethambutol; Hip Joint; Humans; Isoniazid; Leprosy, Borderline; Leprosy, Lepromatous; Male; Rifampin; Tuberculosis, Osteoarticular | 1989 |
Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Leprosy, Borderline; Leprosy, Lepromatous; Leprosy, Tuberculoid; Mycobacterium leprae; Paraguay; Patient Compliance; Prothionamide; Rifampin; Time Factors | 1989 |
Importance of rifampicin in combined daily/intermittent chemotherapy for tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Dapsone; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Microbial Sensitivity Tests; Middle Aged; Prothionamide; Pyrazinamide; Rifampin; Sputum; Tuberculosis, Pulmonary | 1989 |
The first joint THELEP-Sasakawa Memorial Health Foundation workshop on experimental chemotherapy of leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprosy; Mycobacterium leprae; Mycobacterium tuberculosis; Rifampin; Streptomycin; Tuberculosis | 1987 |
Long-term prothionamide compliance: a study carried out in India using a combined formulation containing prothionamide, dapsone and isoniazid.
Topics: Adolescent; Adult; Dapsone; Drug Therapy, Combination; Female; Humans; India; Isoniazid; Isonicotinic Acids; Leprosy, Lepromatous; Leprosy, Tuberculoid; Male; Middle Aged; Monitoring, Physiologic; Patient Compliance; Prothionamide; Time Factors | 1988 |
The Malta experience. Isoprodian-rifampicin combination treatment for leprosy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Middle Aged; Prothionamide; Rifampin | 1986 |
First assessment of the Malta Leprosy Eradication Project.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Evaluation Studies as Topic; Follow-Up Studies; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Malta; Prothionamide; Recurrence; Rifampin | 1986 |
Report of the joint leprosy-tuberculosis project in Paraguay.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Leprosy; Paraguay; Prothionamide; Rifampin; Tuberculosis | 1986 |
The impact of MDT implementation in the Tanzania National TB-Leprosy Programme.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids; Leprostatic Agents; Leprosy; Male; Prothionamide; Rifampin; Tanzania | 1986 |
Recent trends in chemotherapy of leprosy.
Topics: Clofazimine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Leprosy; Mycobacterium leprae; Prothionamide; Rifampin | 1985 |
Failure of a prothionamide-containing oral antituberculosis regimen.
Topics: Administration, Oral; Antitubercular Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Male; Patient Compliance; Prothionamide; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary | 1985 |
[Chemotherapy of leprosy].
Topics: Dapsone; Female; Humans; Isoniazid; Leprosy; Male; Sulfadiazine; Sulfones; Thioacetazone; Urea; Vitamin D | 1970 |
Dapsone acetylation and the treatment of leprosy.
Topics: Acetates; Dapsone; Humans; Isoniazid; Leprosy | 1972 |
Fundamental data, methods and goals of present research on the treatment of leprosy.
Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In Vitro Techniques; Isoniazid; Leprosy; Mice; Mycobacterium lepraemurium; Rifampin; Sulfonamides; Trimethoprim | 1973 |
Activity of compound TH 270 (N-p-isobutoxyphenyl-N'-p'- -pyridyl-ethyl-phenylthiourea) on the experimental infection with Mycobacterium lepraemurium and Mycobacterium leprae.
Topics: Aniline Compounds; Animals; Dapsone; Isoniazid; Mice; Mycobacterium Infections; Mycobacterium leprae; Mycobacterium tuberculosis; Thiourea | 1972 |
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans; Isoniazid; Leprosy; Mice; Models, Biological; Mycobacterium Infections; Phenazines; Pyrazines; Rabbits; Rifampin; Sulfonamides; Trimethoprim | 1972 |
Polymorphic acetylation of drugs in rabbits.
Topics: Acetylation; Aminobenzoates; Aminosalicylic Acids; Animals; Body Temperature; Chromatography, Thin Layer; Dapsone; Female; Genotype; Half-Life; Hydralazine; Intestine, Small; Isoniazid; Lethal Dose 50; Liver; Male; Methemoglobinemia; Phenotype; Polymorphism, Genetic; Rabbits; Structure-Activity Relationship; Sulfamethazine; Sulfanilamides; Time Factors | 1973 |
[Administration of a new antimycobacterial combined therapy in leprosy in East Africa].
Topics: Africa, Eastern; Antitubercular Agents; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Prognosis; Pyrazines; Rifampin; Sulfanilamides; Time Factors | 1973 |
Pharmacokinetics and dosing of antimicrobial agents in renal impairment, Part II.
Topics: Anti-Infective Agents; Bacitracin; Chloramphenicol; Chloroquine; Clindamycin; Dapsone; Ethambutol; Humans; Isoniazid; Kidney Diseases; Methenamine; Nalidixic Acid; Neomycin; Nitrofurantoin; Sulfadimethoxine; Sulfamethizole; Sulfamethoxazole; Sulfamethoxypyridazine; Sulfisomidine; Sulfisoxazole; Vancomycin | 1974 |
[Antimycobacterial activity of isoniazid (INH) in the presence of prothionamid (PTH) and diaminodiphenylsulfone (DDS) in vitro].
Topics: Dapsone; Drug Resistance, Microbial; Drug Synergism; In Vitro Techniques; Isoniazid; Isonicotinic Acids; Microbial Sensitivity Tests; Mycobacterium; Sulfides | 1974 |
Systemic chemotherapy in mice experimentally infected with Mycobacterium marinum.
Topics: Administration, Oral; Animals; Dapsone; Demeclocycline; Ethionamide; Female; Isoniazid; Mice; Mice, Inbred Strains; Mycobacterium Infections; Phenylthiourea; Pyrazines; Rifampin; Sulfonamides | 1971 |
Preliminary test using DMSO as a vehicle for drugs in leprosy.
Topics: Aminosalicylic Acids; Dapsone; Dimethyl Sulfoxide; Humans; Isoniazid; Leprosy; Pharmaceutical Vehicles | 1967 |
Dapsone acetylation in man: another example of polymorphic acetylation.
Topics: Acetates; Acylation; Adult; Blood Proteins; Dapsone; Female; Fluorometry; Genetics, Medical; Half-Life; Humans; Isoniazid; Leprosy; Male; Pharmacogenetics; Phenotype; Philippines; Protein Binding; Sulfamethazine; Time Factors | 1971 |
Multiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases.
Topics: Adolescent; Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Middle Aged; Rifampin; Thioacetazone | 1981 |
Toxic epidermal necrolysis (Lyell syndrome). A case report.
Topics: Dapsone; Drug Combinations; Humans; Isoniazid; Male; Middle Aged; Stevens-Johnson Syndrome; Thioacetazone | 1983 |
Evaluation of drug regimen in lepromatous leprosy--II.
Topics: Adult; Animals; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Mice; Middle Aged; Rifampin; Thioacetazone | 1983 |
An investigation of dapsone compliance using an isoniazid-marked formulation.
Topics: Adolescent; Adult; Aged; Capsules; Creatinine; Dapsone; Drug Combinations; Female; Humans; Isoniazid; Leprosy; Male; Middle Aged; Patient Compliance; Self Administration; Tablets | 1983 |
Antimycobacterial activity of isoniazid + prothionamide + dapsone against a number of randomly selected 'wild' strains of Mycobacterium tuberculosis.
Topics: Dapsone; Drug Synergism; Isoniazid; Isonicotinic Acids; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Prothionamide | 1980 |
Activity of the combination of isoniazid, protionamide and dapsone against Mycobacterium leprae and some other mycobacteria.
Topics: Animals; Dapsone; Drug Interactions; Drug Therapy, Combination; Isoniazid; Isonicotinic Acids; Leprosy; Mice; Mycobacterium; Mycobacterium leprae; Prothionamide | 1981 |
The role of low dosage prothionamide with and without 4,4'-diamino diphenyl sulphone for use with isoniazid in the treatment of experimental mouse tuberculosis.
Topics: Animals; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Isoniazid; Isonicotinic Acids; Mice; Prothionamide; Tuberculosis, Pulmonary | 1982 |
Effects of concurrent administration of other substrates of N-acetyltransferase on dapsone acetylation.
Topics: Acetylation; Acetyltransferases; Animals; Dapsone; Humans; Hydralazine; In Vitro Techniques; Isoniazid; Rats; Sulfamethazine | 1981 |
Acetylator phenotyping: a comparison of the isoniazid and dapsone tests.
Topics: Acetylation; Adult; Aged; Dapsone; Female; Half-Life; Humans; Isoniazid; Male; Middle Aged; Phenotype | 1981 |
Varying distribution of acetylation phenotypes in RA patients with and without Sjögren's syndrome.
Topics: Acetylation; Adult; Aged; Arthritis, Rheumatoid; Dapsone; Female; Humans; Isoniazid; Male; Middle Aged; Phenotype; Sjogren's Syndrome | 1981 |
Study on drug interactions.
Topics: Adult; Clofazimine; Dapsone; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Male; Middle Aged; Rifampin | 1980 |
[Isoprodian in ambulatory therapy of pulmonary tuberculosis].
Topics: Adult; Ambulatory Care; Dapsone; Drug Combinations; Female; Humans; Isoniazid; Isonicotinic Acids; Male; Middle Aged; Prothionamide; Tuberculosis, Pulmonary | 1980 |
Relapse rates in patients treated with dapsone monotherapy and combinations of dapsone and thiambutosine, thiacetazone, isoniazid and streptomycin in the pre-MDT era.
Topics: Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Phenylthiourea; Recurrence; Retrospective Studies; Sex Factors; Skin; Streptomycin; Thioacetazone | 1994 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine | 1995 |
Side-effects of Isoprodian compared with WHO-MDT in rural Nepal.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Middle Aged; Prothionamide; Rural Health | 1993 |
Longitudinal study of tuberculosis outcomes among immunologically naive Aché natives of Paraguay.
Topics: Adolescent; Adult; Age Distribution; Asian People; BCG Vaccine; Child; Child, Preschool; Dapsone; Disease Outbreaks; Drug Combinations; Female; Humans; Indians, South American; Infant; Isoniazid; Longitudinal Studies; Male; Middle Aged; Paraguay; Prevalence; Prothionamide; Risk Factors; Sex Distribution; Tuberculosis | 2003 |
[THE CHEMOTHERAPY OF LEPROSY].
Topics: Cycloserine; Dapsone; Drug Therapy; Humans; Isoniazid; Leprosy; Sulfamethoxypyridazine; Sulfones; Thiosemicarbazones; Thiourea | 1964 |
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.
Topics: Adenosine Triphosphate; Albendazole; Amitriptyline; Animals; Buthionine Sulfoximine; Carbamazepine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chromans; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Activation; Flutamide; Glutathione; Humans; Isoniazid; Microsomes; Ochratoxins; Piperazines; Quinidine; Substrate Specificity; Tamoxifen; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Toxicity Tests; Triazolam; Troglitazone; Xenobiotics | 2005 |
Can leprosy be eradicated with chemotherapy? An evaluation of the Malta Leprosy Eradication Project.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Malta; Program Evaluation; Prothionamide; Rifampin; Treatment Outcome | 2008 |
Bis dihydropyrimidine: synthesis and antimycobacterial activity.
Topics: Acetoacetates; Antitubercular Agents; Benzenesulfonates; Dapsone; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrimidines; Tuberculosis | 2011 |
Multibacillary Mid-Borderline Leprosy with Type 1 Lepra Reaction and Concurrent Latent Tuberculosis.
Topics: Abattoirs; Anti-Inflammatory Agents; Antitubercular Agents; Clofazimine; Dapsone; Diagnosis, Differential; Humans; Isoniazid; Latent Tuberculosis; Leprostatic Agents; Leprosy, Borderline; Leprosy, Multibacillary; Male; Middle Aged; Prednisolone; Rifampin; Thrombophlebitis | 2021 |