dapsone and artesunic acid

dapsone has been researched along with artesunic acid in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.17)18.2507
2000's17 (70.83)29.6817
2010's6 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bygbjerg, IC; Chen, M; Kappel, M; Kharazmi, A; Lemnge, M; Theander, TG1
Jomaa, H; Ortmann, R; Schlitzer, M; Wiesner, J1
Imwong, M; Krudsood, S; Looareesuwan, S; Nonprasert, A; Pukrittayakamee, S; Snounou, G; White, NJ; Wilairatana, P1
A Clode, S; Clark, RL; Gaunt, I; Ward, SA; White, TE; Winstanley, P1
Peters, W; Robinson, BL; Stewart, LB2
Garner, P; Jones, K; Taylor-Robinson, D1
Biagini, GA; Edwards, G1
Nyunt, MM; Plowe, CV1
Biagini, GA; Blencowe, H; Dube-Mbeye, Q; Dunyo, S; Duparc, S; Kanjala, MK; Kanyok, T; Kirby, PL; Molyneux, M; Neate, C; Nyirenda, M; Opara, H; Ward, S; Winstanley, PA; Woessner, M; Wootton, DG1
Curtis, J; D'Alessandro, U; Fanello, CI; Karema, C; Ndahindwa, V; Ngamije, D; Uwimana, A; Van Doren, W; Van Overmeir, C1
Adjuik, M; Amenga-Etego, S; Asante, KP; Chandramohan, D; Dosoo, DK; Greenwood, B; Gyapong, J; Owusu, R; Owusu-Agyei, S1
Avellino, P; Bancone, G; d'Alessandro, U; Fanello, CI; Karema, C; Lee, SJ; Modiano, D; Uwimana, A1
Ishih, A; Kano, S; Kino, H; Muregi, FW1
Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ1
Bandyopadhyay, N; Duparc, S; Kirby, PL; Miller, AK; Ward, SA; Winstanley, PA; Wootton, DG1
Borrmann, S; Duparc, S; Esamai, F; Ezedinachi, EU; Greenwood, B; Guiguemdé, R; Kellam, L; Kirby, PL; Oguche, S; Owusu-Agyei, S; Pamba, A; Premji, Z; Sowunmi, A; Umeh, RE; Ward, SA; Winstanley, PA1
Agbenyega, T; Awobusuyi, J; Carter, N; Dicko, A; Duparc, S; Goh, LE; Greenwood, B; Harrell, E; Ndububa, DA; Pamba, A; Pitmang, S; Tiono, AB; Ward, SA; Winstanley, PA1
Hamel, MJ; Kariuki, S; Lindblade, K; Newman, RD; Odhiambo, FO; Otieno, P; Peterson, E; Slutsker, L; ter Kuile, FO; Vulule, J; Williamson, J1
Clark, RL; Gristwood, WE; Harrell, AW; Lewsley, R; Wilson, R1
Bardsley, B; Barry, SJ; Drozdz, MA; Hancock, SA; Okafo, GN; Szafran, MM1
Carter, N; Duparc, S; Pamba, A; Waitumbi, JN1
Bassat, Q; D' Alessandro, U; Daniel, A; Forret, P; González, R; Machevo, S; Nabasumba, C; Piola, P; Robert, A; Talisuna, A; Turyakira, E; Van Geertruyden, JP; van Loen, H; Van Malderen, C; Van Overmeir, C; Yeka, A1
D'Alessandro, U; Donegan, S; Tudur Smith, C; Williamson, P1

Reviews

3 review(s) available for dapsone and artesunic acid

ArticleYear
New antimalarial drugs.
    Angewandte Chemie (International ed. in English), 2003, Nov-10, Volume: 42, Issue:43

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Design; Drug Resistance; Ethanolamines; Flavonoids; Fluorenes; Fosfomycin; Global Health; Humans; Lumefantrine; Malaria; Naphthoquinones; Naphthyridines; Plasmodium falciparum; Proguanil; Sesquiterpenes

2003
Malaria: uncomplicated, caused by Plasmodium falciparum.
    Clinical evidence, 2005, Issue:13

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Proguanil; Pyrimethamine; Sesquiterpenes; Sulfadoxine

2005
Resisting resistance: dealing with the irrepressible problem of malaria.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Resistance; Humans; Malaria; Proguanil; Sesquiterpenes

2006

Trials

11 trial(s) available for dapsone and artesunic acid

ArticleYear
Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria.
    PloS one, 2008, Mar-05, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Animals; Antimalarials; Artemisia; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Gambia; Humans; Infant; Malaria, Falciparum; Malawi; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Sample Size; Sesquiterpenes; Treatment Outcome

2008
A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008, Volume: 102, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Proguanil; Rural Health; Rwanda; Treatment Outcome

2008
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.
    PloS one, 2008, Jun-25, Volume: 3, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Male; Polymerase Chain Reaction; Proguanil; Treatment Outcome

2008
High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency.
    PloS one, 2008, Volume: 3, Issue:12

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Malaria, Falciparum; Male; Oxidants; Polymorphism, Genetic; Proguanil; Pyrimethamine; Sulfadoxine

2008
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
    PloS one, 2009, Volume: 4, Issue:4

    Topics: Adult; Amodiaquine; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Sulfadoxine; Tanzania; Young Adult

2009
Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria.
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:10

    Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Gambia; Humans; Malaria, Falciparum; Malawi; Male; Middle Aged; Parasitic Sensitivity Tests; Proguanil; Time Factors

2009
Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria.
    PloS one, 2009, Aug-19, Volume: 4, Issue:8

    Topics: Adolescent; Africa; Antimalarials; Artemisinins; Artesunate; Child; Dapsone; Double-Blind Method; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Patient Compliance; Proguanil; Treatment Outcome

2009
Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: a randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria.
    The American journal of tropical medicine and hygiene, 2009, Volume: 81, Issue:6

    Topics: Adolescent; Adult; Africa South of the Sahara; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Double-Blind Method; Drug Therapy, Combination; Female; Glycogen Storage Disease Type I; Hemolysis; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Proguanil; Time Factors

2009
Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial.
    PloS one, 2010, Apr-02, Volume: 5, Issue:4

    Topics: Anemia; Antimalarials; Artemisinins; Artesunate; Dapsone; Double-Blind Method; Drug Combinations; Humans; Incidence; Infant; Kenya; Malaria; Premedication; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome

2010
Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials.
    Malaria journal, 2011, Aug-17, Volume: 10

    Topics: Adolescent; Africa; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; Drug Combinations; Female; Genotype; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Malaria, Falciparum; Male; Phenotype; Proguanil; Treatment Outcome

2011
Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.
    Malaria journal, 2012, Jul-10, Volume: 11

    Topics: Africa South of the Sahara; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Case-Control Studies; Child, Preschool; Dapsone; Drug Combinations; Drug Therapy, Combination; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Malaria; Male; Proguanil

2012

Other Studies

10 other study(ies) available for dapsone and artesunic acid

ArticleYear
In vitro effects of artesunate and other antimalarial agents on the function of human lymphocytes and neutrophils.
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Antimalarials; Artemisinins; Artesunate; Cells, Cultured; Dapsone; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; Lymphocyte Activation; Lymphocytes; Neutrophils; Phytohemagglutinins; Pyrimethamine; Sesquiterpenes; Thymidine; Tritium; Uridine

1994
Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Dihydropteroate Synthase; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Male; Middle Aged; Mutation; Plasmodium falciparum; Proguanil; Prospective Studies; Recurrence; Sesquiterpenes; Tetrahydrofolate Dehydrogenase; Treatment Outcome

2005
Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2004, Volume: 71, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Combinations; Embryonic Development; Female; Fetal Development; Pregnancy; Proguanil; Rabbits; Rats; Rats, Sprague-Dawley; Sesquiterpenes

2004
The chemotherapy of rodent malaria. LXII. Drug combinations to impede the selection of drug resistance, part 5: rates of development of resistance to some inhibitors of folate metabolism and to artesunate.
    Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Therapy, Combination; Folic Acid Antagonists; Malaria, Falciparum; Male; Mice; Parasitemia; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Proguanil; Sesquiterpenes; Triazines

2004
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Plasmodium chabaudi; Plasmodium yoelii; Proguanil; Rodent Diseases; Sesquiterpenes

2005
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine

2007
Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model.
    Experimental parasitology, 2009, Volume: 121, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Synergism; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred ICR; Orotic Acid; Parasitemia; Plasmodium berghei; Pyrimethamine

2009
Localization of artesunate and its derivatives in the pregnant rat and fetus following oral administration and relationship to developmental toxicity.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2010, Volume: 89, Issue:5

    Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Artesunate; Autoradiography; Dapsone; Female; Fetus; Male; Pregnancy; Proguanil; Random Allocation; Rats; Rats, Sprague-Dawley; Tissue Distribution

2010
Formation and identification of a degradant in chlorproguanil-dapsone-artesunate (Dacart™) tablets.
    Journal of pharmaceutical and biomedical analysis, 2011, Feb-20, Volume: 54, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dapsone; Drug Combinations; Drug Stability; Drug Therapy, Combination; Hot Temperature; Humans; Humidity; Magnetic Resonance Spectroscopy; Malaria, Falciparum; Mass Spectrometry; Proguanil; Tablets

2011
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates.
    Statistics in medicine, 2012, Dec-20, Volume: 31, Issue:29

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dapsone; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Meta-Analysis as Topic; Models, Statistical; Outcome Assessment, Health Care; Proguanil; Quinolines; Regression Analysis

2012