dapsone has been researched along with 4-amino-4'-hydroxylaminodiphenylsulfone in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.16) | 18.7374 |
| 1990's | 20 (52.63) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 5 (13.16) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Caiolfa, V; Cennamo, C; De Benedetti, PG; Frassineti, C; Iarossi, D; Menziani, C | 1 |
| Bera, S; Mondal, D | 1 |
| Allen, JM; Baehner, RL; Boxer, LA; Ismail, G | 1 |
| Grossman, SJ; Jollow, DJ; Simson, J | 1 |
| Coleman, MD; Park, BK; Tingle, MD | 1 |
| Haas, M; Harrison, JH | 1 |
| Biggar, WD; Shear, NH; Uetrecht, J; Zahid, N | 1 |
| Baehner, RL; Boxer, LA; Brown, MP; Mantich, NM; Weetman, RM | 1 |
| Kalhorn, TF; Kharasch, ED; Mitra, AK; Slattery, JT; Thummel, KE; Unadkat, JD | 1 |
| Budinsky, RA; Jollow, DJ; McMillan, DC; Simson, JV | 1 |
| Bradshaw, TP; Jollow, DJ; McMillan, DC | 1 |
| Budinsky, R; Grossman, S; Jollow, D | 1 |
| Coleman, MD; Jacobus, DP; Simpson, J | 2 |
| Saab, N; Svensson, CK; Vage, C; Woster, PM | 1 |
| Coleman, MD; Jacobus, DP | 2 |
| Coleman, MD | 1 |
| Gill, HJ; Park, BK; Tingle, MD | 1 |
| Barry, M; Breckenridge, AM; Khoo, SH; O'Mahony, C; Park, BK; Pirmohamed, M; Tingle, MD; Wilkins, EG; Williams, D | 1 |
| Adedoyin, A; Branch, RA; Irshaid, Y | 1 |
| Bradshaw, TP; Crouch, RK; Jollow, DJ; McMillan, DC | 1 |
| Maggs, JL; Mahmud, R; Park, BK; Pirmohamed, M; Tingle, MD | 1 |
| Blasum, C; Gerlach, B; Winter, C; Wozel, G | 1 |
| Jensen, CB; Jollow, DJ; McMillan, DC | 1 |
| Alessandrini, C; Ciccoli, L; Comporti, M; Ferrali, M; Rossi, V; Signorini, C | 1 |
| Jollow, DJ; McMillan, DC | 1 |
| Carlson, TJ; Hutzler, JM; Tracy, TS; Wahlstrom, JL; Wienkers, LC | 1 |
| Greenspan, DL; Hooton, TM; Jacobson, M; Slattery, JT; Trapnell, CB; Unadkat, JD; Winter, HR | 1 |
| Amschler, J; Behrens, D; Clement, B; Havemeyer, A; Matschke, K; Wolf, S | 1 |
| Bowman, ZS; Jollow, DJ; McMillan, DC; Morrow, JD; Powell, CL | 1 |
| Roychowdhury, S; Svensson, CK; Vyas, PM | 1 |
| Bordin, L; Clari, G; Coleman, MD; Fiore, C; Ragazzi, E; Zen, F | 1 |
| Albuquerque, RV; Amado, LL; Borges, RS; Coleman, MD; Dos Santos, DC; Malcher, NS; Monteiro, MC; Valente, SA; Valente, VC | 1 |
| Ambrosini, G; Andrisani, A; Armanini, D; Bordin, L; Bosello Travain, V; Brunati, AM; Dall'Acqua, S; Donà, G; Ragazzi, E; Roveri, A; Sabbadin, C; Tibaldi, E | 1 |
| An, GJ; Bae, ON; Bian, Y; Chung, JH; Kim, K; Lim, KM; Ngo, T | 1 |
| Carneiro, ADS; Coleman, MD; da S Seabra, PS; de Albuquerque, RFV; de Azevedo Sousa, KM; de Oliveira, SBB; Dos Santos, SM; Espíndola, KMM; Figueiredo, RA; Fonseca, ADN; Malcher, NS; Monteiro, MC; Varela, ELP | 1 |
| D'Alessandro, A; Dziewulska, KH; Hay, AM; Reisz, JA; Zimring, JC | 1 |
4 review(s) available for dapsone and 4-amino-4'-hydroxylaminodiphenylsulfone
| Article | Year |
|---|---|
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Dapsone-induced hemolytic anemia.
Topics: Anemia, Hemolytic; Dapsone; Erythrocytes; Hemodynamics; Humans | 1995 |
Dapsone toxicity: some current perspectives.
Topics: Agranulocytosis; Anti-Infective Agents; Dapsone; Humans; Liver; Methemoglobinemia | 1995 |
Oxidative stress, glucose-6-phosphate dehydrogenase and the red cell.
Topics: Dapsone; Erythrocytes; Free Radicals; Glucosephosphate Dehydrogenase; Humans; Oxidants; Oxidative Stress; Phenylhydrazines; Pyrimidinones | 2001 |
2 trial(s) available for dapsone and 4-amino-4'-hydroxylaminodiphenylsulfone
| Article | Year |
|---|---|
Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.
Topics: Adult; Alcohol Deterrents; Anti-Bacterial Agents; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dapsone; Disulfiram; Drug Interactions; Female; Humans; Hydroxylation; Leprostatic Agents; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Troleandomycin | 1995 |
The effect of clarithromycin, fluconazole, and rifabutin on dapsone hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).
Topics: Adult; Algorithms; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Clarithromycin; Dapsone; Female; Fluconazole; HIV Infections; Humans; Male; Middle Aged; Rifabutin | 2004 |
32 other study(ies) available for dapsone and 4-amino-4'-hydroxylaminodiphenylsulfone
| Article | Year |
|---|---|
Quantitative structure-activity analysis in dihydropteroate synthase inhibition by sulfones. Comparison with sulfanilamides.
Topics: Dihydropteroate Synthase; Escherichia coli; Kinetics; Spectrophotometry; Structure-Activity Relationship; Sulfanilamides; Sulfones; Transferases | 1987 |
Improvement of polymorphonuclear leucocyte oxidative and bactericidal functions in chronic granulomatous disease with 4-amino-4'-hydroxylaminodiphenyl sulphone.
Topics: Aminobiphenyl Compounds; Blood Bactericidal Activity; Catalase; Concanavalin A; Dapsone; Glucose; Granulomatous Disease, Chronic; Humans; Immunologic Capping; Neutrophils; Superoxide Dismutase | 1978 |
Dapsone-induced hemolytic anemia: effect of N-hydroxy dapsone on the sulfhydryl status and membrane proteins of rat erythrocytes.
Topics: Anemia, Hemolytic; Animals; Dapsone; Dithiothreitol; Erythrocyte Membrane; Erythrocytes; Glutathione; Membrane Proteins; Rats; Sulfhydryl Compounds | 1992 |
The effect of preincubation with cimetidine on the N-hydroxylation of dapsone by human liver microsomes.
Topics: Adolescent; Adult; Animals; Child; Cimetidine; Dapsone; Humans; Hydroxylation; Male; Methemoglobin; Microsomes, Liver; Middle Aged; NADP; Rats | 1991 |
Stimulation of K-C1 cotransport in rat red cells by a hemolytic anemia-producing metabolite of dapsone.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anemia, Hemolytic; Animals; Anions; Biological Transport; Bumetanide; Dapsone; Dithiothreitol; Erythrocytes; Female; In Vitro Techniques; Kinetics; Potassium Chloride; Rats; Rats, Inbred Strains | 1989 |
Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells.
Topics: Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Azides; Catalase; Cyclooxygenase Inhibitors; Dapsone; Humans; Hydroxylamine; Hydroxylamines; Indomethacin; Leukocytes, Mononuclear; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
In vitro inhibition of granulopoiesis by 4-amino-4'-hydroxylaminodiphenyl sulfone.
Topics: Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Dapsone; Dose-Response Relationship, Drug; Glutathione; Granulocytes; Hematopoiesis; Humans; Hydrogen Peroxide | 1980 |
Dapsone-induced hemolytic anemia: effect of dapsone hydroxylamine on sulfhydryl status, membrane skeletal proteins and morphology of human and rat erythrocytes.
Topics: Anemia, Hemolytic; Animals; Dapsone; Erythrocytes; Humans; Male; Membrane Proteins; Microscopy, Electron; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 1995 |
Dapsone-induced hemolytic anemia: role of glucose-6-phosphate dehydrogenase in the hemolytic response of rat erythrocytes to N-hydroxydapsone.
Topics: Amitrole; Androsterone; Anemia, Hemolytic; Animals; Dapsone; Erythrocytes; Glucosephosphate Dehydrogenase; Glutathione; Hemolysis; Rats | 1995 |
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro. III: Effect of diabetes.
Topics: Dapsone; Diabetes Mellitus; Ditiocarb; Erythrocytes; Glutathione; Humans; Imidazoles; Imidazolidines; Methemoglobin; Models, Chemical; Oxidation-Reduction; Phthalazines; Temperature | 1994 |
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro. IV: Implications for the development of agranulocytosis.
Topics: Agranulocytosis; Cell Death; Dapsone; Diabetes Mellitus; Ditiocarb; Erythrocytes; Humans; Leukocytes, Mononuclear; Methemoglobin; Oxidation-Reduction | 1994 |
Dapsone-induced hematologic toxicity: comparison of the methemoglobin-forming ability of hydroxylamine metabolites of dapsone in rat and human blood.
Topics: Adult; Animals; Ascorbic Acid; Dapsone; Drug Stability; Hematologic Diseases; Humans; Male; Methemoglobin; Models, Biological; Rats; Rats, Sprague-Dawley; Species Specificity; Time Factors | 1994 |
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro--II. Movement of dapsone across a semipermeable membrane into erythrocytes and plasma.
Topics: Cell Membrane Permeability; Dapsone; Dialysis; Erythrocytes; Humans; In Vitro Techniques; Inactivation, Metabolic; Methemoglobin; Oxidation-Reduction; Time Factors | 1993 |
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro.
Topics: Dapsone; Erythrocytes; Glutathione; Humans; In Vitro Techniques; Methemoglobin; Oxidation-Reduction | 1993 |
N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity.
Topics: Anti-Infective Agents; Antifungal Agents; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Humans; Hydroxylation; Ketoconazole; Mixed Function Oxygenases; Sulfaphenazole | 1995 |
Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency.
Topics: Adult; Aged; CD4 Lymphocyte Count; Dapsone; Drug Hypersensitivity; Erythrocytes; Glutathione; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Methemoglobinemia; Middle Aged; Trimethoprim, Sulfamethoxazole Drug Combination | 1996 |
Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes.
Topics: Catalysis; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dapsone; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Substrate Specificity | 1996 |
Formation of free radicals and protein mixed disulfides in rat red cells exposed to dapsone hydroxylamine.
Topics: Animals; Cyclic N-Oxides; Cysteamine; Dapsone; Disulfides; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Hemolysis; Hydroxyl Radical; Hydroxylation; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Salicylates; Spin Labels | 1997 |
Comparison of the metabolism and toxicity of dapsone in rat, mouse and man.
Topics: Acetylation; Animals; Anti-Infective Agents; Carbon Radioisotopes; Dapsone; Erythrocytes; Female; Humans; Male; Methemoglobin; Mice; Rats; Rats, Wistar; Species Specificity | 1997 |
Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study.
Topics: Adult; Chemotaxis, Leukocyte; Dapsone; Female; Humans; Leukotriene B4; Male; Neutrophils; Pilot Projects; Skin | 1997 |
Role of lipid peroxidation in dapsone-induced hemolytic anemia.
Topics: Anemia, Hemolytic; Animals; Dapsone; Erythrocyte Membrane; Erythrocytes; Fatty Acids, Unsaturated; Fluorescent Dyes; Humans; Lipid Peroxidation; Male; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 1998 |
Hemolytic drugs aniline and dapsone induce iron release in erythrocytes and increase the free iron pool in spleen and liver.
Topics: Aniline Compounds; Animals; Dapsone; Erythrocytes; Hemolysis; Hydroxylamines; Iron; Leprostatic Agents; Liver; Male; Methemoglobin; Organ Size; Oxidants; Rats; Rats, Sprague-Dawley; Spleen | 1999 |
Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Dapsone; Flurbiprofen; Humans; Hydroxylation; Inactivation, Metabolic; Kinetics; Mechanics; Models, Biological; NADP; Oxygen | 2003 |
Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
Topics: Animals; Cytochrome P-450 Enzyme System; Cytochrome-B(5) Reductase; Cytochromes b5; Dapsone; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Oxidation-Reduction; Sulfamethoxazole; Swine | 2005 |
Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents.
Topics: Animals; Dapsone; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobins; Hemolysis; Humans; In Vitro Techniques; Lipid Peroxidation; Lipids; Phenylhydrazines; Phosphatidylserines; Proteins; Pyrimidinones; Rats; Reactive Oxygen Species | 2005 |
Formation and uptake of arylhydroxylamine-haptenated proteins in human dendritic cells.
Topics: Biological Transport; Biotransformation; Cell Differentiation; Cell Line; Dapsone; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Microscopy, Confocal; Oxygenases; Peroxidase; Protein Binding; Proteins; Serum Albumin, Bovine; Sulfamethoxazole; Time Factors | 2007 |
Dapsone hydroxylamine induces premature removal of human erythrocytes by membrane reorganization and antibody binding.
Topics: Anion Exchange Protein 1, Erythrocyte; Anti-Infective Agents; Antibodies; Dapsone; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Humans; Immunoglobulin G; Male; Middle Aged; Phosphorylation; Time Factors; Tyrosine | 2010 |
In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells.
Topics: Adult; Antioxidants; Catalase; Cells, Cultured; Dapsone; Erythrocytes; Female; Humans; Male; Methemoglobin; Methemoglobinemia; Middle Aged; Oxidation-Reduction; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Young Adult | 2015 |
Dapsone hydroxylamine-mediated alterations in human red blood cells from endometriotic patients.
Topics: Adult; Carbonic Anhydrases; Dapsone; Endometriosis; Erythrocytes; Female; Humans; Oxidative Stress; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Young Adult | 2017 |
Dapsone Hydroxylamine, an Active Metabolite of Dapsone, Can Promote the Procoagulant Activity of Red Blood Cells and Thrombosis.
Topics: Adult; Animals; Blood Coagulation; Cells, Cultured; Dapsone; Dose-Response Relationship, Drug; Erythrocytes; Hemolysis; Humans; Male; Platelet Aggregation; Rats, Sprague-Dawley; Thrombosis | 2019 |
Alpha-Lipoic Acid and Its Enantiomers Prevent Methemoglobin Formation and DNA Damage Induced by Dapsone Hydroxylamine: Molecular Mechanism and Antioxidant Action.
Topics: Antioxidants; Dapsone; DNA Damage; Methemoglobin; Superoxide Dismutase; Thioctic Acid | 2022 |
Hemolysis and Metabolic Lesion of G6PD Deficient RBCs in Response to Dapsone Hydroxylamine in a Humanized Mouse Model.
Topics: Animals; Dapsone; Erythrocytes; Glucose; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Mice; Phosphates | 2023 |