dantrolene and calpain

dantrolene has been researched along with calpain in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jimenez, LS; Morimoto, H; Palnitkar, SS; Parness, J; Paul-Pletzer, K1
Fischer, DR; Fischer, JE; Gang, G; Hasselgren, PO; James, JH; Molloy, M; Paul, RJ; Pritts, TA; Sun, X; Williams, AB1
Anagli, J; Hotchkiss, RS; Strasberg, SM; Topp, SA; Upadhya, GA1
Bell, GI; Han, Z; Horikawa, Y; Johnson, JD; Misler, S; Otani, K; Polonsky, KS; Wu, H; Ye, H; Zhang, Y1
Aleshin, AN; Bando, Y; Katayama, T; Manabe, T; Tohyama, M1
Campos, EC; Celes, MR; Malvestio, LM; O'Connell, JL; Prado, CM; Ramos, SG; Romano, MM; Rossi, MA; Simões, MV1
Gieseg, SP; Whiteman, M; Yang, YT1
Campos, EC; Celes, MR; da Silva, JS; Figueiredo, MJ; Freitas, AC; Malvestio, LM; Prado, CM; Rossi, MA; Spray, DC; Suadicani, SO; Tanowitz, HB1
Chai, J; Chu, W; Duan, H; Li, D; Ma, L; Yu, Y1
Blanner, P; Brown, CM; Greer, PA; Hara, T; Hershey, T; Kanekura, K; Lu, S; Mahadevan, J; Marshall, BA; Martinez, R; Neilson, A; Oslowski, CM; Semenkovich, CF; Spears, LD; Toyoda, M; Umezawa, A; Urano, F; Yamazaki-Inoue, M1
Chen, D; Li, ST; Qiu, YW; Xu, MY1

Other Studies

11 other study(ies) available for dantrolene and calpain

ArticleYear
The skeletal muscle ryanodine receptor identified as a molecular target of [3H]azidodantrolene by photoaffinity labeling.
    Biochemistry, 2001, Jan-16, Volume: 40, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calpain; Cattle; Dantrolene; Dithiothreitol; Hydrolysis; Ligands; Molecular Weight; Muscle, Skeletal; Myocardium; Peptide Fragments; Photoaffinity Labels; Precipitin Tests; Rabbits; Reducing Agents; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tritium

2001
Dantrolene reduces serum TNFalpha and corticosterone levels and muscle calcium, calpain gene expression, and protein breakdown in septic rats.
    Shock (Augusta, Ga.), 2001, Volume: 15, Issue:3

    Topics: Animals; Calcium; Calpain; Corticosterone; Dantrolene; Male; Muscle Proteins; Muscle Relaxants, Central; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha

2001
Effect of cold preservation on intracellular calcium concentration and calpain activity in rat sinusoidal endothelial cells.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:2

    Topics: Animals; Calcium; Calcium Channel Blockers; Calpain; Cathepsins; Cells, Cultured; Chelating Agents; Cryopreservation; Cysteine Endopeptidases; Dantrolene; Egtazic Acid; Endothelium, Vascular; Intracellular Membranes; Liver Circulation; Male; Multienzyme Complexes; Osmolar Concentration; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley

2003
RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
    The Journal of biological chemistry, 2004, Jun-04, Volume: 279, Issue:23

    Topics: Animals; Apoptosis; Calcium; Calpain; Caspase 3; Caspases; Cell Survival; Dantrolene; Enzyme Activation; Gene Expression Regulation; Glucagon-Like Peptides; Glucose; Humans; Islets of Langerhans; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Palmitic Acids; Peptides; Protein Isoforms; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors

2004
GRP94 reduces cell death in SH-SY5Y cells perturbated calcium homeostasis.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Blotting, Western; Calcimycin; Calcium; Calpain; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dantrolene; DNA, Antisense; Endoplasmic Reticulum; Gene Expression; Histocytochemistry; Homeostasis; HSP70 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Lac Operon; Membrane Proteins; Neurons; Thapsigargin; Transfection

2004
Calpain-mediated dystrophin disruption may be a potential structural culprit behind chronic doxorubicin-induced cardiomyopathy.
    European journal of pharmacology, 2011, Nov-30, Volume: 670, Issue:2-3

    Topics: Actins; Animals; Body Weight; Calpain; Cardiomyopathies; Cell Membrane Permeability; Dantrolene; Doxorubicin; Dystrophin; Electrocardiography; Heart; Lung; Male; Myocardium; Myosins; Organ Size; Rats; Rats, Wistar; Sarcolemma; Survival Analysis; Time Factors

2011
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:2

    Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; Dantrolene; Enzyme Inhibitors; Flunarizine; Humans; Hypochlorous Acid; Lysosomes; Macrophages; Membrane Potential, Mitochondrial; Muscle Relaxants, Central; Necrosis; Nifedipine; Verapamil

2012
Disruption of calcium homeostasis in cardiomyocytes underlies cardiac structural and functional changes in severe sepsis.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Actins; Animals; Animals, Newborn; Blotting, Western; Calcium; Calpain; Cecum; Cells, Cultured; Dantrolene; Dystrophin; Fluorescent Antibody Technique; Hemodynamics; Homeostasis; Intracellular Space; Ligation; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Punctures; Sarcomeres; Sepsis; Stroke Volume; Survival Analysis; Verapamil

2013
[Effect and mechanism of dantrolene on skeletal muscle of rats with severe scald injury].
    Zhonghua yi xue za zhi, 2014, Apr-15, Volume: 94, Issue:14

    Topics: Animals; Burns; Calcium; Calpain; Dantrolene; Disease Models, Animal; Male; Muscle, Skeletal; Rats; Rats, Wistar

2014
A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Dec-09, Volume: 111, Issue:49

    Topics: Adolescent; Adult; Animals; Calcium; Calpain; Cell Death; Cell Line; Child; Dantrolene; Endoplasmic Reticulum; Female; Fibroblasts; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Infant, Newborn; Male; Membrane Proteins; Mice; Mice, Knockout; Mutation; Neural Stem Cells; Protein Binding; Rats; Wolfram Syndrome

2014
Beneficial effects of dantrolene on sepsis-induced diaphragmatic dysfunction are associated with downregulation of high-mobility group box 1 and calpain-caspase-3 proteolytic pathway.
    The Journal of surgical research, 2016, Volume: 200, Issue:2

    Topics: Animals; Biomarkers; Calpain; Caspase 3; Dantrolene; Diaphragm; Dose-Response Relationship, Drug; Down-Regulation; HMGB1 Protein; Male; Muscle Relaxants, Central; Proteolysis; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis

2016