Page last updated: 2024-08-23

danazol and cyclosporine

danazol has been researched along with cyclosporine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (30.00)	18.2507
2000's	7 (23.33)	29.6817
2010's	14 (46.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ohno, A; Sugino, N; Tanaka, M	1
Keller, F; Passfall, J; Schuller, I	1
Blatt, J; Burckart, G; Howrie, D; Orlando, S	1
Bachman, WR; Brennan, JK	1
Dodds, WJ	1
Chin, M; Harada, K; Kojima, S; Mugishima, H; Ryo, S; Shichino, H; Shimada, T; Suzuki, T; Takamura, M	1
Ezaki, K; Hirano, M; Ino, T; Okamoto, M; Tsuzuki, M; Yamaguchi, T	1
Borrás-Blasco, J; Conesa-Garcia, V; Gonzalez-Delgado, M; Navarro-Ruiz, J; Peris-Marti, J; Rosique-Robles, JD	1
Chemlal, K; Clauvel, JP; Grange, MJ; Lassoued, K; Wyplosz, B	1
Hibi, S; Kojima, S; Kosaka, Y; Mugishima, H; Ohara, A; Sugita, K; Tsuchida, M; Tsukimoto, I; Yabe, H; Yamamoto, M	1
Adachi, M; Akaike, J; Hayashi, T; Hinoda, Y; Hirayama, T; Imai, K; Kasahara, K; Minami, T; Takahashi, S; Takahashi, T	1
Jing, L; Liu, H; Shao, Z	1
Abrahamsson, B; Forsell, P; Forssén, S; Knutson, L; Lennernäs, H; Nordgren, A; Ohgren, C; Persson, EM	1
Charkoftaki, G; Kytariolos, J; Macheras, P	1
Jalaeikhoo, H; Khajeh-Mehrizi, A	1
Ge, M; Huang, J; Huang, Z; Li, X; Nie, N; Shao, Y; Shi, J; Wang, M; Zhang, J; Zheng, Y	1
Bose, P; Khadwal, A; Khurana, H; Lad, D; Malhotra, P; Prakash, G; Sachdeva, MU; Varma, N; Varma, S; Yanamandra, U	1

Reviews

2 review(s) available for danazol and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Possible cyclosporin-danazol interaction in a patient with aplastic anaemia. American journal of hematology, 1999, Volume: 62, Issue:1 Topics: Adult; Anemia, Aplastic; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Danazol; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Inactivation, Metabolic; Male	1999

Trials

2 trial(s) available for danazol and cyclosporine

Article	Year
Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia. Blood, 2000, Sep-15, Volume: 96, Issue:6 Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Danazol; Drug Therapy, Combination; Estrogen Antagonists; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Treatment Outcome	2000
[The effectiveness of cyclosporin A in the treatment of autoimmune hemolytic anemia and Evans syndrome]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2001, Volume: 22, Issue:11 Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Cyclosporine; Danazol; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prednisone; Recurrence; Treatment Outcome	2001

Article

Year

Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia.

Blood, 2000, Sep-15, Volume: 96, Issue:6

Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Danazol; Drug Therapy, Combination; Estrogen Antagonists; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Treatment Outcome

2000

[The effectiveness of cyclosporin A in the treatment of autoimmune hemolytic anemia and Evans syndrome].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2001, Volume: 22, Issue:11

Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Cyclosporine; Danazol; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prednisone; Recurrence; Treatment Outcome

2001

Other Studies

26 other study(ies) available for danazol and cyclosporine

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
[Drugs and other substances inducing hypertension]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl Topics: Antidepressive Agents, Tricyclic; Contraceptives, Oral; Cyclosporine; Danazol; Erythropoietin; Extracellular Space; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hypertension; Monoamine Oxidase Inhibitors; Recombinant Proteins; Sodium, Dietary	1992
Pharmacokinetics of cyclosporin during administration of danazol. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:12 Topics: Cyclosporine; Danazol; Drug Interactions; Humans; Metabolic Clearance Rate; Middle Aged	1994
Interaction between cyclosporine and danazol in a pediatric patient. Journal of pediatric hematology/oncology, 1996, Volume: 18, Issue:1 Topics: Anemia, Aplastic; Child; Cyclosporine; Danazol; Drug Interactions; Estrogen Antagonists; Humans; Immunosuppressive Agents; Male	1996
Refractory thrombotic thrombocytopenic purpura treated with cyclosporine. American journal of hematology, 1996, Volume: 51, Issue:1 Topics: Adult; Combined Modality Therapy; Cyclosporine; Danazol; Drug Resistance; Female; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Interleukins; Methylprednisolone Hemisuccinate; Plasma Exchange; Pregnancy; Pregnancy Complications, Hematologic; Purpura, Thrombotic Thrombocytopenic; Splenectomy; Vincristine	1996
Immunosuppressive drug therapy. The Canadian veterinary journal = La revue veterinaire canadienne, 1996, Volume: 37, Issue:3 Topics: Animals; Cats; Cyclosporine; Danazol; Dogs; Immunosuppressive Agents	1996
Treatment of aplastic anemia with antithymocyte globulin, cyclosporin A, methylprednisolone, danazol and recombinant human granulocyte-colony stimulating factor. Acta paediatrica Japonica : Overseas edition, 1996, Volume: 38, Issue:6 Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Danazol; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Recombinant Proteins	1996
[Myelodysplastic syndrome with monosomy 7 following combination therapy with granulocyte colony-stimulating factor, cyclosporin A and danazole in an adult patient with severe aplastic anemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:9 Topics: Adult; Anemia, Aplastic; Chromosomes, Human, Pair 7; Cyclosporine; Danazol; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Monosomy; Myelodysplastic Syndromes	1997
Salvage therapy and long-term remission with danazol and cyclosporine in refractory Evan's syndrome. American journal of hematology, 1999, Volume: 62, Issue:3 Topics: Adult; Anemia, Hemolytic, Autoimmune; Cyclosporine; Danazol; Drug Therapy, Combination; Estrogen Antagonists; Humans; Immunosuppressive Agents; Male; Purpura, Thrombocytopenic; Remission Induction; Salvage Therapy; Syndrome	1999
Fatal acute hepatic failure induced by danazol in a patient with endometriosis and aplastic anemia. Journal of gastroenterology, 2001, Volume: 36, Issue:11 Topics: Anemia, Aplastic; Cyclosporine; Danazol; Endometriosis; Estrogen Antagonists; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Liver Failure, Acute; Middle Aged	2001
Improved understanding of the effect of food on drug absorption and bioavailability for lipophilic compounds using an intestinal pig perfusion model. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, May-10, Volume: 34, Issue:1 Topics: Animals; Biological Availability; Cyclosporine; Danazol; Food; Intestinal Absorption; Jejunum; Particle Size; Perfusion; Solubility; Swine	2008
Novel milk-based oral formulations: proof of concept. International journal of pharmaceutics, 2010, May-10, Volume: 390, Issue:2 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Buffers; Chemistry, Pharmaceutical; Cyclosporine; Danazol; Ethanol; Humans; Male; Meloxicam; Milk; Solubility; Thiazines; Thiazoles	2010
Immunosuppressive therapy in patients with aplastic anemia: a single-center retrospective study. PloS one, 2015, Volume: 10, Issue:5 Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Danazol; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Young Adult	2015
Outcome of a novel immunosuppressive strategy of cyclosporine, levamisole and danazol for severe aplastic anemia. International journal of hematology, 2015, Volume: 102, Issue:2 Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Clonal Evolution; Cyclosporine; Danazol; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Levamisole; Male; Middle Aged; Prognosis; Recurrence; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult	2015
Danazol increases T regulatory cells in patients with aplastic anemia. Hematology (Amsterdam, Netherlands), 2018, Volume: 23, Issue:8 Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Danazol; Female; Humans; Male; Middle Aged; Prospective Studies; T-Lymphocytes, Regulatory	2018