dactinomycin has been researched along with wortmannin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 17 (77.27) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kikkawa, U; Konishi, H; Kuroda, S; Matsuzaki, H; Ono, Y; Tanaka, M; Tokunaga, C | 1 |
| Anand-Srivastava, MB; Ge, C | 1 |
| Cotter, TG; Knox, KA; McGahon, AJ; McKenna, SL; O'Gorman, DM | 1 |
| Cuttle, KA; Goldstein, RH; Kuang, PP; Poliks, CF; Ricupero, DA; Rishikof, DC | 1 |
| Pawelczyk, T; Podgorska, M; Sakowicz, M; Szczepanska-Konkel, M | 1 |
| Ihn, H; Tamaki, K; Yamane, K | 1 |
| Anel, A; Boyer, C; Buferne, M; Martínez-Lorenzo, MJ; Naval, J; Pardo, J; Schmitt-Verhulst, AM | 1 |
| Casalini, P; Casati, B; Galmozzi, E; Iorio, MV; Ménard, S; Olgiati, C | 1 |
| Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G | 1 |
| Sullivan, CV; Weber, GM | 1 |
| Allenspach, R; Erne, P; Ivanov, D; Joshi, MB; Philippova, M; Resink, TJ | 1 |
| Lillehaug, JR; Martinez, A; Reigstad, LJ; Varhaug, JE | 1 |
| Bhattacharyya, SP; Mukherjee, D; Paul, S; Sen, U | 1 |
| Cai, L; Cai, S; Li, W; Li, X | 1 |
| Hanai, Y; Kozawa, O; Takai, S; Tokuda, H | 1 |
| Moore, AB; Sullivan, CV; Weber, GM | 1 |
| Ganapathy, V; Kashiwagi, H; Sugawara, M; Takekuma, Y; Yamazaki, K | 1 |
| Hirata, H; Inagaki, H; Iwashita, K; Kamata, H; Kawauchi, K; Morikawa, T; Moriyama, Y; Shibukawa, Y; Tobiume, K | 1 |
| Carraro-Lacroix, LR; Girardi, AC; Malnic, G | 1 |
| Borst, O; Fröhlich, H; Gawaz, M; Lang, F; Münzer, P; Pelzl, L; Schmid, E; Schmidt, EM; Tolios, A; Walker, B | 1 |
| Chang, HH; Huang, YM; Juan, CC; Kao, CC; Kao, YH; Kuo, YC; Liu, CW; Tang, YC | 1 |
22 other study(ies) available for dactinomycin and wortmannin
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase.
Topics: 3T3 Cells; Androstadienes; Animals; Anisomycin; Blood Proteins; Cell Line; Chlorocebus aethiops; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Hot Temperature; Isoenzymes; Mice; Oligopeptides; Osmolar Concentration; Peptides; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Sequence Tagged Sites; Sorbitol; Stress, Physiological; Transfection; Wortmannin | 1996 |
Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in AII-mediated enhanced expression of Gi proteins in vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dactinomycin; Embryo, Mammalian; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Rats; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Transcription, Genetic; Wortmannin | 1998 |
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin | 2000 |
Phosphatidylinositol 3-kinase-dependent stabilization of alpha1(I) collagen mRNA in human lung fibroblasts.
Topics: 3T3 Cells; Androstadienes; Animals; Blotting, Northern; Cells, Cultured; Chromones; Collagen; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Kinetics; Lung; Mice; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA Stability; RNA, Messenger; Transfection; Wortmannin | 2001 |
Insulin induces expression of adenosine kinase gene in rat lymphocytes by signaling through the mitogen-activated protein kinase pathway.
Topics: Adenosine Kinase; Androstadienes; Animals; Bucladesine; Cells, Cultured; Culture Media, Serum-Free; Dactinomycin; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Enzyme Inhibitors; ets-Domain Protein Elk-1; Gene Expression Regulation, Enzymologic; Insulin; Lymphocytes; MAP Kinase Signaling System; Molecular Sequence Data; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Sirolimus; Spleen; Transcription Factors; Wortmannin | 2003 |
Epidermal growth factor up-regulates expression of transforming growth factor beta receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblast
Topics: Androstadienes; Cells, Cultured; Chromones; Dactinomycin; Dermis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Humans; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Scleroderma, Systemic; Signal Transduction; Transfection; Up-Regulation; Wortmannin | 2003 |
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
Topics: Acetophenones; Androstadienes; Animals; Antibodies, Monoclonal; Benzopyrans; Carbazoles; Cell Degranulation; Cell Line; Chromones; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Fas Ligand Protein; Humans; Indoles; Ionomycin; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Glycoproteins; Mice; Morpholines; Perforin; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pore Forming Cytotoxic Proteins; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Wortmannin | 2003 |
HER2 signaling enhances 5'UTR-mediated translation of c-Myc mRNA.
Topics: 5' Untranslated Regions; Androstadienes; Carcinoma; Cell Line, Tumor; Clone Cells; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, myc; Genes, Reporter; Humans; Luciferases; Neuregulin-1; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Biosynthesis; Protein Kinases; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin | 2004 |
Insulin-like growth factor-I induces oocyte maturational competence but not meiotic resumption in white bass (Morone chrysops) follicles in vitro: evidence for rapid evolution of insulin-like growth factor action.
Topics: 1-Octanol; Androstadienes; Animals; Bass; Chromones; Cortodoxone; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Female; Gap Junctions; Heptanol; Humans; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Meiosis; Morpholines; Oocytes; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Wortmannin | 2005 |
T-cadherin protects endothelial cells from oxidative stress-induced apoptosis.
Topics: Adenoviridae; Androstadienes; Apoptosis; Cadherins; Caspases; Cell Survival; Cells, Cultured; Dactinomycin; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoblotting; Immunohistochemistry; Immunosuppressive Agents; MAP Kinase Signaling System; Microscopy, Fluorescence; Models, Biological; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction; Sirolimus; Staurosporine; Time Factors; Tumor Necrosis Factor-alpha; Wortmannin | 2005 |
Nuclear localisation of endogenous SUMO-1-modified PDGF-C in human thyroid tissue and cell lines.
Topics: Amino Acid Sequence; Androstadienes; Animals; Carcinoma, Papillary; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cells, Cultured; Chromatin; Cytosol; Dactinomycin; Gene Expression Regulation; HeLa Cells; Humans; Lymphokines; Mice; Molecular Sequence Data; NIH 3T3 Cells; Platelet-Derived Growth Factor; Protein Conformation; Serum; SUMO-1 Protein; Thyroid Gland; Thyroid Neoplasms; Wortmannin | 2006 |
In vitro effects of insulin-like growth factors and insulin on oocyte maturation and maturation-inducing steroid production in ovarian follicles of common carp, Cyprinus carpio.
Topics: Androstadienes; Animals; Carps; Cattle; Chorionic Gonadotropin; Chromones; Cycloheximide; Dactinomycin; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Insulin; Morpholines; Oocytes; Ovarian Follicle; Somatomedins; Species Specificity; Steroids; Time Factors; Wortmannin | 2006 |
Anti-apoptotic effect of hepatocyte growth factor from actinomycin D in hepatocyte-derived HL7702 cells is associated with activation of PI3K/Akt signaling.
Topics: Androstadienes; Apoptosis; Cell Line; Dactinomycin; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Hepatocyte Growth Factor; Hepatocytes; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Wortmannin | 2006 |
Activation of phosphatidylinositol 3-kinase/Akt limits FGF-2-induced VEGF release in osteoblasts.
Topics: Androstadienes; Animals; Cells, Cultured; Chromones; Dactinomycin; Enzyme Activation; Fibroblast Growth Factor 2; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Morpholines; Osteoblasts; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A; Wortmannin | 2007 |
In vitro actions of insulin-like growth factor-I on ovarian follicle maturation in white perch (Morone americana).
Topics: Androstadienes; Animals; Bass; Chromones; Cycloheximide; Dactinomycin; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Morpholines; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Sexual Maturation; Steroids; Wortmannin | 2007 |
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Topics: Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acids; Androstadienes; Animals; Anthracenes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Flavonoids; Insulin; Insulin Antagonists; Muscle, Skeletal; Osmotic Pressure; Protein Synthesis Inhibitors; Rats; Up-Regulation; Wortmannin | 2009 |
Cycloprodigiosin hydrochloride activates the Ras-PI3K-Akt pathway and suppresses protein synthesis inhibition-induced apoptosis in PC12 cells.
Topics: Androstadienes; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cycloheximide; Cytoprotection; Dactinomycin; Indoles; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; ras Proteins; Rats; Signal Transduction; Wortmannin | 2008 |
Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.
Topics: Ammonium Chloride; Androstadienes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Buffers; Cell Line, Transformed; Cell Membrane; Cycloheximide; Dactinomycin; Epithelial Cells; Gene Expression; Genistein; Hydrogen-Ion Concentration; Imidazoles; Kidney Tubules, Proximal; Losartan; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Subunits; Protein Transport; Protein-Tyrosine Kinases; Pyridines; Rats; Time Factors; Up-Regulation; Vacuolar Proton-Translocating ATPases; Wortmannin | 2009 |
Thrombin-sensitive expression of the store operated Ca(2+) channel Orai1 in platelets.
Topics: Androstadienes; Blood Platelets; Calcium; Calcium Channels; Chromones; Dactinomycin; Gene Expression Regulation; Humans; Morpholines; ORAI1 Protein; Phosphatidylinositol 3-Kinases; Platelet Activation; Puromycin; RNA Precursors; RNA, Messenger; Thrombin; Thrombosis; Time Factors; Wortmannin | 2013 |
Endothelin-1 stimulates resistin gene expression.
Topics: 3T3-L1 Cells; Adipose Tissue; Androstadienes; Animals; Anthracenes; Butadienes; Chromones; Dactinomycin; Endothelin-1; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Morpholines; Nitriles; Oligopeptides; Piperidines; Proto-Oncogene Proteins c-akt; Resistin; Signal Transduction; STAT3 Transcription Factor; Tyrphostins; Wortmannin | 2014 |