dactinomycin and warfarin

dactinomycin has been researched along with warfarin in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199023 (74.19)18.7374
1990's1 (3.23)18.2507
2000's1 (3.23)29.6817
2010's6 (19.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brown, JM; Carmel, RJ1
Clarke, CH; Shankel, DM1
Bloom, AL; Giddings, JC; Peake, IR; Shaw, E1
Anderson, J; Nievel, JG; Robinson, N1
Anderson, J; Nievel, JG; Skrbic, TR1
Hahlbrock, K; Ragg, H1
Kipfer, RK; Olson, RE; Walz, DA1
Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G1
Scharf, R; Ullrich, V2
Alden, R; Gaetani, S; Hill, RB; Johnson, BC; Paolucci, AM; RamaRao, PB; Ranhotra, GS; Shah, DV; Shah, VK1
Karu, AE; Linn, S1
Gaudernack, G; Prydz, H1
Cooper, SD; Feuer, G1
Feuer, G1
Olson, RE1
Johnston, MF; Olson, RE1
Polson, JB; Wosilait, WD1
Bell, RG; Matschiner, JT1
Golberg, L; Nievel, JG1
Lowenthal, J; Simmons, EL1
Fox, N; Studzinski, GP1
Alnemri, ES; Chen, M; Itoh, T; Moran, J; Pleasure, D; Reddy, UR1
FEELEY, J; MARCUS, A1
Kurata, T; Saito, S; Sakashita, K; Uchida, E; Watanabe, T1

Reviews

3 review(s) available for dactinomycin and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antimutagenesis in microbial systems.
    Bacteriological reviews, 1975, Volume: 39, Issue:1

    Topics: Acridines; Antipsychotic Agents; Bacteria; Caffeine; Chloramphenicol; Dactinomycin; Dibenzocycloheptenes; DNA Repair; Escherichia coli; Fungi; Genes; Histidine; Manganese; Mutagens; Mutation; Phenothiazines; Polyamines; Purine Nucleosides; Quinacrine; Radiation Effects; Rosaniline Dyes; Ultraviolet Rays; Uracil; Warfarin

1975
The mode of action of vitamin K.
    Nutrition reviews, 1970, Volume: 28, Issue:7

    Topics: Animals; Bacteria; Chickens; Coumarins; Cycloheximide; Dactinomycin; Drug Antagonism; Factor VII; Prothrombin; Puromycin; Rats; Vitamin K

1970

Other Studies

28 other study(ies) available for dactinomycin and warfarin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
The effect of cyclophosphamide and other drugs on the incidence of pulmonary metastases in mice.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Age Factors; Animals; Antineoplastic Agents; Aspirin; Cyclophosphamide; Dactinomycin; Dose-Response Relationship, Drug; Female; Immunosuppression Therapy; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasm Transplantation; Plicamycin; Radiation Effects; Sarcoma, Experimental; Warfarin

1977
Synthesis of procoagulant factor VIII, factor VIII related antigen and other coagulation factors by the isolated perfused rat liver.
    British journal of haematology, 1979, Volume: 41, Issue:4

    Topics: Animals; Antigens; Blood Coagulation Factors; Cycloheximide; Dactinomycin; Factor VIII; Immunoelectrophoresis, Two-Dimensional; In Vitro Techniques; Liver; Male; Rats; Warfarin

1979
Changes in nucleotide metabolism of the liver and fate of [14C]orotate among various pyrimidines at the outset and during induction of drug-metabolizing enzymes and hepatomegaly.
    Biochemical Society transactions, 1976, Volume: 4, Issue:3

    Topics: Animals; Azauridine; Butylated Hydroxytoluene; Coumarins; Dactinomycin; DNA Replication; Enzyme Induction; Hepatomegaly; Liver; Orotic Acid; Phenobarbital; Protein Biosynthesis; Rats; Ribonucleotides; Transcription, Genetic; Uracil

1976
Studies on the relationship between induction of drug-metabolizing enzymes, liver enlargement and ascorbic acid excretion in rodents.
    Biochemical Society transactions, 1976, Volume: 4, Issue:3

    Topics: Animals; Ascorbic Acid; Azauridine; Butylated Hydroxytoluene; Coumarins; Dactinomycin; Enzyme Induction; Female; Glucuronates; Hepatomegaly; Liver; Orotic Acid; Phenobarbital; Proadifen; Rats; Transcription, Genetic; Uracil; Uracil Nucleotides

1976
Light-induced changes of enzyme activities in parsley cell suspension cultures. Effects of inhibitors of RNA and protein synthesis.
    Archives of biochemistry and biophysics, 1975, Volume: 166, Issue:1

    Topics: Ammonia-Lyases; Cells, Cultured; Chloramphenicol; Coenzyme A Ligases; Coumarins; Cycloheximide; Dactinomycin; Flavonoids; Isomerases; Light; Phenylalanine; Plant Proteins; Plants; Protein Biosynthesis; Puromycin; RNA; Time Factors; Transcription, Genetic

1975
Effects of vitamin K deficiency, warfarin, and inhibitors of protein synthesis upon the plasma levels of vitamin K-dependent clotting factors in the chick.
    The Journal of nutrition, 1975, Volume: 105, Issue:8

    Topics: Animals; Blood Coagulation Tests; Chickens; Cycloheximide; Dactinomycin; Factor IX; Factor X; Protein Biosynthesis; Prothrombin; Puromycin; Species Specificity; Time Factors; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin

1975
Microsomal phospholipids and drug action--quantitative biochemical and electron microscopic studies.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1972, Volume: 5, Issue:4

    Topics: Animals; Carbon Tetrachloride; Choline; Coumarins; Dactinomycin; Endoplasmic Reticulum; Ethanol; Ethionine; Female; Glucose-6-Phosphatase; Hexobarbital; Histocytochemistry; In Vitro Techniques; Male; Methylcholanthrene; Microscopy, Electron; Microsomes, Liver; Nitrosamines; Phenobarbital; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats

1972
In vitro induction of drug monooxygenase activity by phenobarbital in the isolated mouse jejunum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:3

    Topics: Animals; Carbon Isotopes; Coumarins; Dactinomycin; Dealkylation; Enzyme Induction; In Vitro Techniques; Intestinal Mucosa; Jejunum; Leucine; Male; Mice; Oxygenases; Phenobarbital; Protein Binding; Protein Biosynthesis; Puromycin

1973
In vitro induction by phenobarbital of drug monooxygenase activity in mouse isolated small intestine.
    Biochemical pharmacology, 1974, Volume: 23, Issue:15

    Topics: Animals; Carbon Radioisotopes; Coumarins; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dactinomycin; Dealkylation; Enzyme Induction; Fluorometry; Hydrogen-Ion Concentration; Intestinal Mucosa; Jejunum; Leucine; Male; Mice; Microsomes; NADP; Oxygenases; Perfusion; Phenobarbital; Puromycin; Spectrophotometry, Ultraviolet; Time Factors

1974
Vitamin K and biosynthesis of protein and prothrombin.
    The Journal of biological chemistry, 1968, Jul-25, Volume: 243, Issue:14

    Topics: Amino Acids; Animals; Carbon Isotopes; Cycloheximide; Dactinomycin; Dicumarol; Liver; Male; Microsomes; Mitochondria, Liver; Protein Biosynthesis; Prothrombin; Prothrombin Time; Puromycin; Rats; Time Factors; Ultrasonics; Vitamin K; Vitamin K Deficiency; Warfarin

1968
Uncoupling of the recBC ATPase from DNase by DNA crosslinked with psoralen.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:10

    Topics: Adenosine Triphosphatases; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Coumarins; Dactinomycin; Deoxyribonucleases; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Ethidium; Furans; Genetic Linkage; Micrococcal Nuclease; Neurospora crassa; Pancreas; Protein Binding; Radiation Effects; Recombination, Genetic; Tritium; Ultraviolet Rays

1972
Studies on the biosynthesis of factor VII (proconvertin). The mode of action of warfarin.
    Biochimica et biophysica acta, 1971, Feb-23, Volume: 230, Issue:2

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Blood Coagulation Tests; Carbon Isotopes; Cyclic AMP; Cycloheximide; Dactinomycin; Diphosphates; Edetic Acid; Factor VII; In Vitro Techniques; Leucine; Ligases; Liver; Magnesium; Male; Membranes; Microsomes, Liver; Orotic Acid; Potassium; Puromycin; Pyruvate Kinase; Pyruvates; Rats; Sodium; Time Factors; Tritium; Ultrasonics; Warfarin

1971
Relation between drug-metabolizing activity and phospholipids in hepatic microsomes. I. Effects of phenobarbital, carbon tetrachloride, and actinomycin D.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:6

    Topics: Animals; Carbon Tetrachloride; Chromatography, Thin Layer; Coumarins; Dactinomycin; Enzyme Induction; Female; Glucose-6-Phosphatase; Lysophosphatidylcholines; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phosphatidylethanolamines; Phospholipids; Proteins; Rats; Stimulation, Chemical

1972
3-Hydroxylation of coumarin or 4-methylcoumarin by rat-liver microsomes and its induction by 4-methylcoumarin given orally.
    Chemico-biological interactions, 1970, Volume: 2, Issue:3

    Topics: Animals; Coumarins; Dactinomycin; Enzyme Induction; Female; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; NAD; NADP; Phospholipases; Proadifen; Proteins; Rats; Surface-Active Agents

1970
Studies of prothrombin biosynthesis in cell-free systems. 3. Regulation by vitamin K and warfarin of prothrombin biosynthesis in rat liver microsomes.
    The Journal of biological chemistry, 1972, Jun-25, Volume: 247, Issue:12

    Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Isotopes; Cell-Free System; Coumarins; Dactinomycin; In Vitro Techniques; Iodine Isotopes; Male; Microsomes, Liver; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Prothrombin; Radioimmunoassay; Rats; Time Factors; Vitamin K; Vitamin K Deficiency; Warfarin

1972
Effect of selected antibiotics on prothrombin time of rats and the relationship to coumarin anticoagulants.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 132, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cricetinae; Cycloheximide; Dactinomycin; Factor VII; Female; Injections, Intraperitoneal; Prothrombin Time; Puromycin; Rats; Vitamin K; Warfarin

1969
Synthesis and destruction of prothrombin in the rat.
    Archives of biochemistry and biophysics, 1969, Volume: 135, Issue:1

    Topics: Animals; Blood Coagulation Tests; Cycloheximide; Dactinomycin; Depression, Chemical; Liver; Male; Metabolism; Naphthoquinones; Protein Biosynthesis; Prothrombin; Rats; RNA; Stimulation, Chemical; Time Factors; Tritium; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin

1969
Effect of coumarin and other compounds on ribosomal protein synthesis in the rat liver.
    Nature, 1968, Aug-24, Volume: 219, Issue:5156

    Topics: Amino Acids; Animals; Coumarins; Cresols; Dactinomycin; Depression, Chemical; Female; Liver; Male; Oils; Phenobarbital; Polynucleotides; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Stimulation, Chemical; Uracil Nucleotides; Zea mays

1968
Failure of actinomycin D to inhibit appearance of clotting activity by vitamin K in vitro.
    Experientia, 1967, Jun-15, Volume: 23, Issue:6

    Topics: Animals; Citrates; Dactinomycin; Factor VII; In Vitro Techniques; Liver; Rats; Ribosomes; RNA, Messenger; Vitamin K; Vitamin K 1; Warfarin

1967
DNA dependence and inhibition by novobiocin and coumermycin of the nucleolar adenosine triphosphatase (ATPase) of human fibroblasts.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1982, Volume: 30, Issue:4

    Topics: Adenosine Triphosphatases; Aminocoumarins; Anti-Bacterial Agents; Cell Nucleolus; Coumarins; Dactinomycin; DNA; Fibroblasts; Humans; Kinetics; Lung; Microscopy, Electron; Novobiocin; Osmolar Concentration; Transcription, Genetic

1982
Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP.
    Journal of neurochemistry, 1999, Volume: 73, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bucladesine; Calcium; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Colforsin; Coumarins; Cyclic AMP; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Gene Expression Regulation, Enzymologic; Neurons; Oligopeptides; Potassium; Protein Synthesis Inhibitors; Rats; Transcription, Genetic

1999
ISOCITRIC LYASE FORMATION IN THE DISSECTED PEANUT COTYLEDON.
    Biochimica et biophysica acta, 1964, Jul-08, Volume: 89

    Topics: Cold Temperature; Cotyledon; Coumarins; Dactinomycin; Fluorouracil; Lyases; Metabolism; Pharmacology; Plants; Research; Spectrophotometry

1964
Multiple Internal Jugular Vein Thromboses in a Patient With Localized Rhabdomyosarcoma.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Cyclophosphamide; Dactinomycin; Female; Heparin; Humans; Jugular Veins; Rhabdomyosarcoma; Thrombosis; Tomography, X-Ray Computed; Vincristine; Warfarin

2018