dactinomycin and u 0126

Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Butadienes; Carbazoles; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; DNA Fragmentation; Drug Synergism; Embryo, Mammalian; Enzyme Inhibitors; Female; Imidazoles; Immunoglobulin G; Indole Alkaloids; Kinetics; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Nitric Oxide Donors; Nitriles; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptor, trkB; Signal Transduction

Topics: Anisomycin; Blotting, Northern; Blotting, Western; Butadienes; Calcium; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Ionophores; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Monocytes; Nitriles; p38 Mitogen-Activated Protein Kinases; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins

Topics: Apoptosis; Breast Neoplasms; Butadienes; Chymotrypsin; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Inhibitors; Female; Flavonoids; Humans; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Nitriles; Oligopeptides; Proteasome Endopeptidase Complex; Tumor Cells, Cultured

Topics: Butadienes; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Endothelium, Vascular; Humans; I-kappa B Proteins; Interleukin-6; Leupeptins; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Multienzyme Complexes; Nitriles; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Umbilical Veins

Topics: Activating Transcription Factor 2; Analysis of Variance; Animals; Butadienes; Cyclic AMP Response Element-Binding Protein; Dactinomycin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Immunoblotting; Ischemic Preconditioning, Myocardial; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardium; Nitriles; Nucleic Acid Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; RNA, Messenger; Swine; Transcription Factors

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Butadienes; Carrier Proteins; Cell Line; Chromones; Cricetinae; Cricetulus; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; JNK Mitogen-Activated Protein Kinases; Lung; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction

Topics: 3T3 Cells; Animals; Biological Transport; Butadienes; Cycloheximide; Dactinomycin; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kinetics; Mice; Naphthalenes; Nitriles; Osteoblasts; Phosphates; Protein Kinase C; Sodium; Time Factors

Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butadienes; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dactinomycin; Enzyme Inhibitors; Female; Gene Expression Profiling; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Melanoma; Mitogen-Activated Protein Kinase Kinases; Nitriles; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Paclitaxel

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Agents; Apoptosis; Butadienes; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Melanoma; Mice; Nitriles; Phosphorylation; Protein Kinase C; Tumor Necrosis Factor-alpha

Topics: Animals; Antioxidants; Blotting, Northern; Blotting, Western; Butadienes; Cell Line; Cells, Cultured; Dactinomycin; DNA, Complementary; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Genes, Dominant; Kidney Tubules; Kinetics; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Nitriles; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Puromycin; Rats; RNA; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Up-Regulation

Topics: Aldosterone; Animals; Butadienes; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hydrocortisone; Kidney Cortex; Kidney Tubules, Collecting; Mice; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-raf

Topics: Aged; Aged, 80 and over; Aspartic Acid Endopeptidases; Astrocytes; Butadienes; Cell Division; Cell Hypoxia; Cell Line, Tumor; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Humans; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Nitriles; Oligopeptides; Optic Disk; Protease Inhibitors; Tumor Necrosis Factor-alpha

Topics: Animals; Animals, Newborn; Blotting, Western; Butadienes; Cardiomegaly; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Silencing; Genistein; Imidazoles; Janus Kinases; Myocytes, Cardiac; Nitriles; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Stress, Mechanical

Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Benzhydryl Compounds; Blood Glucose; Butadienes; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Fulvestrant; Half-Life; Leptin; MAP Kinase Kinase 1; Mice; Nitriles; Nucleic Acid Synthesis Inhibitors; Phenols; Phosphorylation; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Resistin; RNA Stability; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation

Topics: Animals; Butadienes; Carbazoles; Cyclic AMP; Dactinomycin; Emetine; Extracellular Signal-Regulated MAP Kinases; Female; Guanine Nucleotide Exchange Factors; Hippocampus; Isoproterenol; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Synaptic Transmission; Transcription, Genetic

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Butadienes; Cell Death; Cell Line, Tumor; Chromones; Dactinomycin; Drug Resistance, Neoplasm; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oncogene Proteins, Fusion; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; RNA, Small Interfering; Sarcoma, Ewing; Signal Transduction; Transcription Factors; Transfection

Topics: Animals; Butadienes; Cell Cycle; Cell Line; Dactinomycin; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Imidazoles; MAP Kinase Kinase 4; Mice; Microtubules; Nitriles; Nocodazole; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; RNA; Signal Transduction; Tubulin; Tumor Necrosis Factor-alpha

Topics: Animals; Butadienes; Coronary Vessels; Dactinomycin; Disease Models, Animal; Endothelin-1; Endothelin-3; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Ischemia; Nitriles; Organ Culture Techniques; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Time Factors; Transcription, Genetic; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms

Topics: 3T3-L1 Cells; Adipose Tissue; Androstadienes; Animals; Anthracenes; Butadienes; Chromones; Dactinomycin; Endothelin-1; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Morpholines; Nitriles; Oligopeptides; Piperidines; Proto-Oncogene Proteins c-akt; Resistin; Signal Transduction; STAT3 Transcription Factor; Tyrphostins; Wortmannin

Topics: Butadienes; Cell Differentiation; Dactinomycin; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; MCF-7 Cells; Nitriles; RNA Stability; Signal Transduction

Topics: Animals; Butadienes; Calcium Channels, L-Type; Cells, Cultured; Cycloheximide; Dactinomycin; Guinea Pigs; MAP Kinase Signaling System; Muscle Cells; Muscle, Smooth; Nitriles; Peptides, Cyclic; Trachea; Tumor Necrosis Factor-alpha