dactinomycin and staurosporine

dactinomycin has been researched along with staurosporine in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's47 (56.63)18.2507
2000's28 (33.73)29.6817
2010's8 (9.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y1
Araujo, LM; Bazzocchi, IL; Jiménez, IA; Llanos, GG; Moujir, LM1
Bohnert, M; Dahse, HM; Hoffmeister, D; König, S; Scherer, O; Werz, O; Wiechmann, K1
Hue, L; Maisin, L; Marchand, MJ; Rousseau, GG1
Chen, T; Mathews, S; Meier, RW; Niklaus, G; Tobler, A1
al-Awqati, Q; Herzlinger, D; Koseki, C1
Ikeda, K; Kikuchi, T; Matsumoto, T; Morimoto, K; Nakano, T; Ogata, E; Okazaki, R; Sakamoto, A; Urakawa, K1
Schatz-Munding, M; Ullrich, V1
Inui, J; Kusuhara, H; Shimada, O1
Ishihara, H; Shikita, M; Takeuchi, K; Tsuneoka, K1
Norman-O'Guin, K; Shafit-Zagardo, B; Sharma, N1
Coffee, KA; Cook, JA; Geisel, J; Halushka, PV; Wise, WC1
Faucon Biguet, N; Mallet, J; Vyas, S1
Moore, JJ; Moore, RM; Vander Kooy, D1
Honma, Y; Hozumi, M; Kasukabe, T; Okabe-Kado, J; Umezawa, K1
Choi, BM; Chung, HT; Jun, CD; Kim, HM; Kwak, HJ; Lee, BS; Paik, SG; Um, JY1
Brozna, JP; Carson, SD; Forman, M1
Jenkins, MK; Mondino, A1
Catravas, JD; Ganapathy, V; Leibach, FH; Papapetropoulos, A; Ramamoorthy, JD; Ramamoorthy, S1
Jenkins, TA; Snyder, TL; Wuthrich, RP1
Hirata, Y; Imai, T; Kanno, K; Marumo, F1
Bates, SE; Dickstein, B; Fojo, AT; Lee, JS; Spolyar, M1
Blok, LJ; Gong, Y; Lindzey, JK; Perry, JE; Tindall, DJ1
Armelin, HA; Armelin, MC; Kimura, E; Sonobe, MH1
LaPointe, MC; Sitkins, JR1
Mitchell, MD; Pollard, JK1
Collins, JL; Manning, K; Powell, CB1
Kameoka, M; Kamiya, T; Kojima, K; Tanaka, Y; Tohno, Y; Yoshihara, K1
D'Adamio, L; Lacanà, E; Vito, P1
Iversen, PO; Lopez, AF; To, LB1
Bali, JP; Combettes, S; Hollande, F; Magous, R1
Gess, B; Kurtz, A; Sandner, P1
Benahmed, M; Kolodié, L; Le Magueresse-Battistoni, B; Pernod, G1
Grumbles, RM; Howell, DS; Jeffrey, JJ; Shao, L1
Chhatwal, GS; Jungnitz, H; Rohde, M; Valentin-Weigand, P; Zock, A1
Benahmed, M; Kolodié, L; Le Magueresse-Battistoni, B; Morera, AM; Pernod, G1
Beyaert, R; Declercq, W; Fiers, W; Vandenabeele, P; Vercammen, D1
Gschwendt, M; Kittstein, W; Krammer, PH; Möller, P; Sträter, J; von Reyher, U1
Harnett, MM; Houslay, MD; Michie, AM; Rena, G1
Arioka, M; Kitamoto, K; Kouhashi, M; Takatsuki, A; Yamasaki, M; Yoda, K1
Brennand, JE; Calder, AA; Greer, IA; Kelly, RW; Leask, R1
Kamp, DW; Panos, RJ; Pollack, N; Sporn, PH; Wu, KI1
Kuusisto, E; Kyrylenko, S; Roschier, M; Salminen, A1
Adams, GE; Hasan, NM; Joiner, MC1
Amarante-Mendes, GP; Cotter, TG; Finucane, DM; Green, DR; Martin, SJ; Salvesen, GS1
Anand-Srivastava, MB; Ge, C; Palaparti, A1
Amarante-Mendes, GP; Cotter, TG; Finucane, DM; Green, DR; Waterhouse, NJ1
Canzoniero, LM; Choi, WS; Gwag, BJ; Kim, JE; Lee, EB; O'Malley, KL; Oh, TH; Oh, YJ; Sensi, SL; Sohn, S1
Humphreys, DT; Wilson, MR1
Amendola, A; Oliverio, S; Piacentini, M; Rodolfo, C; Spinedi, A1
Asai, A; Kirino, T; Kuchino, Y; Narita, Y1
Ehleiter, D; Fuks, Z; Haimovitz-Friedman, A; Kolesnick, R; Liao, WC; Lozano, J; Menendez, S; Morales, A; Wagman, R1
Büssing, A; Pfüller, U; Schietzel, M; Stein, GM1
Adorno, D; Amadori, S; Boffo, V; Campagnano, L; Casciani, CU; Cococcetta, NY; Iacona, A; Sconocchia, G1
Biller-Ckovric, I; Cordes, V; Ferrando-May, E; Görlich, D; Mirkovic, J; Nicotera, P1
Banerjee, PR; Bhadra, R; Deshpande, M; Mitra, D; Mitra, DK; Pal, S; Parab, P; Prasad, DV; Saha, B; Sharma, S; Venuprasad, K1
Belka, C; Berdel, WE; Kreuter, M; Los, M; Renz, A; Schulze-Osthoff, K1
Adrain, C; Creagh, EM; Martin, SJ1
Igarashi, A; Yamaguchi, M1
Aspegren, A; Bridge, E1
Kim, EJ; Park, TH; Rhee, WJ1
Filgueira, L; Forte, P; Groscurth, P; Matter-Reissmann, UB; Schneider, MK; Seebach, JD1
Baran, V; Fabian, D; Koppel, J; Rehak, P1
Li, C; Schwartz, SM; Shah, PK; Sharifi, BG; Wallner, K; Wu, KJ1
Ando, K; Chang, YC; Magae, J; Nakajima, H; Ozawa, S; Togashi, M; Tsuruga, M1
Andreau, K; Castedo, M; Kroemer, G; Larochette, N; Perfettini, JL; Pichart, E; Roumier, T; Souquere, S; Vivet, S1
Acosta, TJ; Bah, MM; Korzekwa, A; Okuda, K; Shibaya, M; Skarzynski, DJ; Woclawek-Potocka, I1
Eley, A; Geary, I; Hakimi, H; Hosseinzadeh, S; Pacey, AA1
Adams, SR; Goldstein, JC; Green, DR; Kelekar, A; Muñoz-Pinedo, C; Ricci, JE; Schuler, M; Tsien, RY1
Gajkowska, B; Orzechowski, A; Pajak, B1
Allenspach, R; Erne, P; Ivanov, D; Joshi, MB; Philippova, M; Resink, TJ1
Bober, A; Korzekwa, A; Okuda, K; Skarzynski, DJ; Woclawek-Potocka, I1
Colbère-Garapin, F; Labadie, K; Martin-Latil, S; Saulnier, A1
Chander, R; Deorukhkar, AA; Pandey, R; Sainis, KB1
Daniel, PT; Essmann, F; Gillissen, BF; Graupner, V; Jänicke, RU; Neise, D; Schulze-Osthoff, K1
Bechthold, A; Luzhetskyy, A; Méndez, C; Salas, JA1
Inoue, M; Li, Q; Sato, EF; Zhu, X1
He, GW; Kamei, K; Lee, KB; Radu, CG; Shu, CJ; Silverman, R; Takahashi, H; Tseng, HR; Wang, X; Witte, ON; Yu, ZT1
Beck, GR; Chang, SH; Cho, MH; Hwang, SK; Kim, JE; Lee, KH; Minai-Tehrani, A; Park, J; Yu, KN1
Miteva, K; Schnichels, S; Schultheiss, M; Spitzer, MS; Szurman, P; Van Linthout, S; Warstat, K1
Breitenbuecher, F; Guyot, M; Hoffarth, S; Höhn, Y; Meiler, J; Schuler, M; Wesarg, E1
Darwich, Z; Klymchenko, AS; Kucherak, OA; Mély, Y; Richert, L1
Akagi, J; Darzynkiewicz, Z; Dobrucki, J; Errington, R; Kordon, M; Matuszek, A; Smith, PJ; Takeda, K; Wlodkowic, D; Zhao, H1

Other Studies

83 other study(ies) available for dactinomycin and staurosporine

ArticleYear
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites

2011
Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Chlorocebus aethiops; Humans; Inhibitory Concentration 50; Plant Extracts; Structure-Activity Relationship; Vero Cells; Withania; Withanolides

2012
Melleolides induce rapid cell death in human primary monocytes and cancer cells.
    Bioorganic & medicinal chemistry, 2014, Aug-01, Volume: 22, Issue:15

    Topics: Apoptosis; Cell Survival; Cells, Cultured; HeLa Cells; Humans; K562 Cells; Microscopy; Monocytes; Oligopeptides; Staurosporine; Structure-Activity Relationship

2014
Activation of 6-phosphofructo-2-kinase by pp60v-src is an indirect effect.
    The Biochemical journal, 1992, Jul-15, Volume: 285 ( Pt 2)

    Topics: Alkaloids; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Dactinomycin; Enzyme Activation; Enzyme Stability; Fibroblasts; Fructosediphosphates; Hot Temperature; Kinetics; Liver; Oncogene Protein pp60(v-src); Phosphofructokinase-2; Phosphotransferases; Protein Kinase C; Staurosporine; Substrate Specificity

1992
The differentiation pathway of HL60 cells is a model system for studying the specific regulation of some myeloid genes.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:10

    Topics: Actins; Alkaloids; Antigens, CD; Base Sequence; CD18 Antigens; Cell Differentiation; Dactinomycin; Gene Expression Regulation, Leukemic; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Male; Molecular Sequence Data; Monocytes; Muramidase; Neoplasm Proteins; Neoplastic Stem Cells; Peroxidase; Protein Kinase C; RNA, Neoplasm; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Apoptosis in metanephric development.
    The Journal of cell biology, 1992, Volume: 119, Issue:5

    Topics: Alkaloids; Animals; Apoptosis; Cycloheximide; Dactinomycin; Embryonic Induction; Epidermal Growth Factor; Epidermis; Mesoderm; Nephrons; Organ Culture Techniques; Phorbol Esters; Protein Kinase C; Rats; Spinal Cord; Staurosporine; Ureter

1992
Transcriptional activation of c-fos and c-jun protooncogenes by serum growth factors in osteoblast-like MC3T3-E1 cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Cell Differentiation; Cycloheximide; Dactinomycin; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Growth Substances; Insulin-Like Growth Factor I; Isoquinolines; Mice; Osteoblasts; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transforming Growth Factor beta

1992
Priming of human polymorphonuclear leukocytes with granulocyte-macrophage colony-stimulating factor involves protein kinase C rather than enhanced calcium mobilisation.
    European journal of biochemistry, 1992, Mar-01, Volume: 204, Issue:2

    Topics: Alkaloids; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Cations, Divalent; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate

1992
Effect of 25-hydroxycholesterol on cholesteryl ester formation in Caco-2 cells.
    Lipids, 1992, Volume: 27, Issue:6

    Topics: Alkaloids; Cell Line; Cholesterol Esters; Cycloheximide; Dactinomycin; Humans; Hydroxycholesterols; Intestinal Mucosa; Intestines; Kinetics; Microsomes; Protein Kinase C; Staurosporine; Sterol O-Acyltransferase

1992
Barbiturates enhance retinoic acid or 1,25-dihydroxyvitamin D3-induced differentiation of leukemia HL-60 cells.
    Biochemical and biophysical research communications, 1991, Jul-15, Volume: 178, Issue:1

    Topics: Alkaloids; Barbiturates; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Pentobarbital; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin

1991
Phorbol-12-myristate-13-acetate (PMA) and inhibitors of protein kinase C alter glial fibrillary acidic protein (GFAP) mRNA levels.
    Glia, 1991, Volume: 4, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Astrocytoma; Dactinomycin; Glial Fibrillary Acidic Protein; Humans; Isoquinolines; Piperazines; Protein Kinase C; RNA; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1991
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
    Biochimica et biophysica acta, 1991, Aug-20, Volume: 1085, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Camptothecin; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Endotoxins; Enterotoxins; Enzyme Activation; Isoquinolines; Macrophages; Male; Piperazines; Protein Biosynthesis; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2

1991
Transcriptional and post-transcriptional regulation of tyrosine hydroxylase gene by protein kinase C.
    The EMBO journal, 1990, Volume: 9, Issue:11

    Topics: Alkaloids; Animals; Blotting, Northern; Cell Line; Dactinomycin; Gene Expression; Gene Expression Regulation, Enzymologic; Protein Kinase C; Rats; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tyrosine 3-Monooxygenase

1990
Protein kinase-C activation is required for oxytocin-induced prostaglandin production in human amnion cells.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases

1991
Inhibition of abl oncogene tyrosine kinase induces erythroid differentiation of human myelogenous leukemia K562 cells.
    Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:11

    Topics: Alkaloids; Antibiotics, Antineoplastic; Azepines; Benzoquinones; Cell Differentiation; Cell Division; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Erythrocytes; Genes, abl; Genistein; Humans; Hydroquinones; In Vitro Techniques; Isoflavones; Lactams, Macrocyclic; Leukemia, Myeloid; Myosin-Light-Chain Kinase; Oligonucleotides, Antisense; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Quinones; Rifabutin; RNA, Messenger; Sphingosine; Staurosporine

1990
Synergistic cooperation between phorbol ester and IFN-gamma for induction of nitric oxide synthesis in murine peritoneal macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Oct-15, Volume: 153, Issue:8

    Topics: Alkaloids; Amino Acid Oxidoreductases; Animals; Base Sequence; Cells, Cultured; Dactinomycin; DNA Primers; Drug Synergism; Gene Expression; Interferon-gamma; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mycobacterium bovis; Mycobacterium Infections; Nitric Oxide; Nitric Oxide Synthase; Polymyxin B; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

1994
Staurosporine blocks down-regulation of monocyte-associated tissue factor.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1994, Volume: 5, Issue:6

    Topics: Alkaloids; Base Sequence; Cells, Cultured; Dactinomycin; Humans; Lipopolysaccharides; Molecular Sequence Data; Monocytes; Naphthalenes; Polycyclic Compounds; Polymerase Chain Reaction; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Thromboplastin

1994
Accumulation of sequence-specific RNA-binding proteins in the cytosol of activated T cells undergoing RNA degradation and apoptosis.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: Alkaloids; Animals; Antibodies, Monoclonal; Apoptosis; Base Sequence; Blotting, Northern; Columbidae; Cyclosporine; Cytochrome c Group; Cytosol; Dactinomycin; Enzyme Inhibitors; Hybridomas; Interleukin-2; Lymphocyte Activation; Lymphokines; Molecular Sequence Data; Receptors, Antigen, T-Cell; Restriction Mapping; RNA; RNA Probes; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Staurosporine; T-Lymphocytes; Uridine

1995
Cyclic AMP-independent up-regulation of the human serotonin transporter by staurosporine in choriocarcinoma cells.
    The Journal of biological chemistry, 1995, Jul-21, Volume: 270, Issue:29

    Topics: Alkaloids; Carrier Proteins; Cholera Toxin; Choriocarcinoma; Cocaine; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Female; Humans; Isoquinolines; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Pregnancy; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1995
Regulation of cytokine-stimulated vascular cell adhesion molecule-1 expression in renal tubular epithelial cells.
    Transplantation, 1993, Volume: 55, Issue:1

    Topics: Alkaloids; Animals; Cell Adhesion Molecules; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Epithelium; Female; Kidney Tubules; Mice; Mice, Inbred C3H; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1

1993
Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:1

    Topics: Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Blotting, Northern; Calmodulin; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Interleukin-1; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Protein Kinase C; Rats; Recombinant Proteins; RNA, Messenger; Staurosporine; Sulfonamides

1993
Differential modulation of P-glycoprotein transport by protein kinase inhibition.
    Biochemistry, 1993, Sep-07, Volume: 32, Issue:35

    Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carrier Proteins; Cyclosporine; Dactinomycin; Dihydropyridines; Drug Resistance; Humans; Isoenzymes; Membrane Glycoproteins; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine

1993
Calcium regulation of androgen receptor expression in the human prostate cancer cell line LNCaP.
    Endocrinology, 1995, Volume: 136, Issue:5

    Topics: Alkaloids; Apoptosis; Blotting, Northern; Blotting, Western; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Line; Cell Nucleus; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression; Humans; Kinetics; Male; Prostatic Neoplasms; Protein Kinase C; Receptors, Androgen; RNA, Messenger; RNA, Neoplasm; Staurosporine; Terpenes; Thapsigargin; Tumor Cells, Cultured

1995
Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives.
    Molecular endocrinology (Baltimore, Md.), 1993, Volume: 7, Issue:11

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alkaloids; Animals; Bucladesine; Colforsin; Cycloheximide; Dactinomycin; Enzyme Induction; Genes, fos; Genes, jun; Kinetics; Mice; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Phorbol ester stimulates the synthesis and secretion of brain natriuretic peptide from neonatal rat ventricular cardiocytes: a comparison with the regulation of atrial natriuretic factor.
    Molecular endocrinology (Baltimore, Md.), 1993, Volume: 7, Issue:10

    Topics: Alkaloids; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Dactinomycin; Heart Ventricles; Kinetics; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1993
Tumor necrosis factor alpha stimulates amnion prostaglandin biosynthesis primarily via an action on fatty acid cyclooxygenase.
    Prostaglandins, 1993, Volume: 46, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1993
Interferon-alpha (IFN alpha) induces a cytolytic mechanism in ovarian carcinoma cells through a protein kinase C-dependent pathway.
    Gynecologic oncology, 1993, Volume: 50, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Emetine; Female; Humans; Interferon alpha-2; Interferon-alpha; Isoquinolines; Ovarian Neoplasms; Piperazines; Protein Biosynthesis; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Inhibition and down-regulation of poly(ADP-ribose) polymerase results in a marked resistance of HL-60 cells to various apoptosis-inducers.
    Cellular and molecular biology (Noisy-le-Grand, France), 1995, Volume: 41, Issue:6

    Topics: Adenosine; Alkaloids; Apoptosis; Calcimycin; Camptothecin; Dactinomycin; DNA, Neoplasm; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Enzyme Inhibitors; HL-60 Cells; Humans; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Staurosporine; Teniposide

1995
Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3.
    Science (New York, N.Y.), 1996, Jan-26, Volume: 271, Issue:5248

    Topics: Alkaloids; Alzheimer Disease; Amino Acid Sequence; Animals; Apoptosis; Apoptosis Regulatory Proteins; Calcium; Calcium-Binding Proteins; Cell Line; Cloning, Molecular; Dactinomycin; Dexamethasone; DNA, Complementary; Fas Ligand Protein; fas Receptor; Hybridomas; Interleukin-2; Membrane Glycoproteins; Membrane Proteins; Mice; Molecular Sequence Data; Presenilin-2; Receptors, Antigen, T-Cell; Signal Transduction; Staurosporine; T-Lymphocytes; Transfection; Up-Regulation

1996
Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-02, Volume: 93, Issue:7

    Topics: Acute Disease; Alkaloids; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Cycloheximide; Cytokines; Dactinomycin; Enzyme Inhibitors; Genistein; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Isoflavones; Kinetics; Leukemia, Myeloid; Phosphorylation; Point Mutation; Protein Kinase C; Protein-Tyrosine Kinases; Reference Values; Staurosporine; Stem Cell Factor

1996
Gastrin stimulation of histamine synthesis in enterochromaffin-like cells from rabbit fundic mucosa.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Alkaloids; Animals; Cells, Cultured; Cholera Toxin; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Gastric Fundus; Gastric Mucosa; Gastrins; Gene Expression; Histamine; Histidine Decarboxylase; Kinetics; Pertussis Toxin; Polymyxin B; Protein Kinase C; Rabbits; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1996
Differential effects of kinase inhibitors on erythropoietin and vascular endothelial growth factor gene expression in rat hepatocytes.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:3

    Topics: Alkaloids; Animals; Base Sequence; Cells, Cultured; Dactinomycin; Endothelial Growth Factors; Enzyme Inhibitors; Erythropoietin; Gene Expression Regulation, Developmental; Genistein; Glyceraldehyde-3-Phosphate Dehydrogenases; Isoflavones; Liver; Molecular Sequence Data; Oxygen Consumption; Phosphotransferases; Protein Kinase C; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Staurosporine; Uridine

1996
Plasminogen activator inhibitor-1 regulation in cultured rat peritubular cells by basic fibroblast growth factor and transforming growth factor-alpha.
    Endocrinology, 1996, Volume: 137, Issue:10

    Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Fibroblast Growth Factor 2; Kidney Tubules; Plasminogen Activator Inhibitor 1; Protein Kinase C; Rats; Recombinant Proteins; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha

1996
Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D3, interleukin-1 beta, and okadaic acid.
    Journal of cellular biochemistry, 1996, Dec-15, Volume: 63, Issue:4

    Topics: Actins; Animals; Blotting, Northern; Carcinogens; Cartilage; Cells, Cultured; Cholecalciferol; Collagenases; Dactinomycin; DNA, Complementary; Electrophoresis, Agar Gel; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, Reporter; Interleukin-1; Male; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection

1996
Characterization of group B streptococcal invasion in HEp-2 epithelial cells.
    FEMS microbiology letters, 1997, Feb-01, Volume: 147, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cadaverine; Calcium; Cells, Cultured; Cytoskeleton; Dactinomycin; Enzyme Inhibitors; Epithelium; Genistein; Humans; Isoflavones; Liver; Microscopy, Electron; Microscopy, Electron, Scanning; Nocodazole; Signal Transduction; Staurosporine; Streptococcal Infections; Streptococcus agalactiae; Virulence

1997
Tumor necrosis factor-alpha regulates plasminogen activator inhibitor-1 in rat testicular peritubular cells.
    Endocrinology, 1997, Volume: 138, Issue:3

    Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Isoflavones; Male; Plasminogen Activator Inhibitor 1; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Staurosporine; Testis; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Up-Regulation

1997
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
    Cytokine, 1997, Volume: 9, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Apoptosis; Dactinomycin; Enzyme Inhibitors; fas Receptor; Humans; Lithium Chloride; Mice; Necrosis; Nucleic Acid Synthesis Inhibitors; Serine Proteinase Inhibitors; Staurosporine; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.
    Cancer research, 1998, Feb-01, Volume: 58, Issue:3

    Topics: Antigens, Neoplasm; Apoptosis; Brefeldin A; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Cycloheximide; Cyclopentanes; Dactinomycin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Humans; Immunologic Capping; Interferon-gamma; Intestinal Mucosa; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Upregulation of cAMP-specific PDE-4 activity following ligation of the TCR complex on thymocytes is blocked by selective inhibitors of protein kinase C and tyrosyl kinases.
    Cell biochemistry and biophysics, 1998, Volume: 28, Issue:2-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Alkaloids; Animals; Benzophenanthridines; CD3 Complex; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Mice; Mice, Inbred BALB C; Nucleic Acid Synthesis Inhibitors; Phenanthridines; Protein Kinase C; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymus Gland; Up-Regulation

1998
Multidrug resistance phenotype conferred by overexpressing bfr2+/pad1+/sks1+ or pap1+ genes and mediated by bfr1+ gene product, a structural and functional homologue of P-glycoprotein in Schizosaccharomyces pombe.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:2

    Topics: Anti-Bacterial Agents; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brefeldin A; Carbazoles; Cyclopentanes; Cytochalasin B; Dactinomycin; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Fungal Proteins; Gene Expression Regulation, Fungal; Indole Alkaloids; Macrolides; Mycotoxins; Pancreatitis-Associated Proteins; Phenotype; Protein Kinase C; Protein Synthesis Inhibitors; Repressor Proteins; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Sequence Analysis, DNA; Staurosporine

1998
Mechanisms involved in the stimulatory effect of amniotic fluid on prostaglandin production by human fetal membranes.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:5

    Topics: Amniotic Fluid; Cells, Cultured; Cesarean Section; Chorion; Cycloheximide; Dactinomycin; Dinoprost; Dinoprostone; Enzyme Inhibitors; Extraembryonic Membranes; Female; Genistein; Humans; Labor, Obstetric; Pregnancy; Prostaglandins; Staurosporine

1998
Keratinocyte growth factor promotes alveolar epithelial cell DNA repair after H2O2 exposure.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aphidicolin; Cell Death; Cycloheximide; Dactinomycin; DNA Damage; DNA Repair; Enzyme Inhibitors; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Genistein; Growth Substances; Humans; Hydrogen Peroxide; Kinetics; Lung Neoplasms; Naphthalenes; Protein Kinase C; Protein-Tyrosine Kinases; Pulmonary Alveoli; Rats; Staurosporine; Tumor Cells, Cultured

1998
Expression of seizure-related PTZ-17 is induced by potassium deprivation in cerebellar granule cells.
    Biochemical and biophysical research communications, 1998, Nov-09, Volume: 252, Issue:1

    Topics: Aging; Animals; Apoptosis; Cells, Cultured; Cerebellum; Dactinomycin; Nerve Tissue Proteins; Neurons; Okadaic Acid; Oncogene Proteins; Potassium Deficiency; Rats; Rats, Wistar; RNA, Messenger; Seizures; Staurosporine; Transcription, Genetic

1998
Effect of serum starvation on expression and phosphorylation of PKC-alpha and p53 in V79 cells: implications for cell death.
    International journal of cancer, 1999, Jan-29, Volume: 80, Issue:3

    Topics: Animals; Apoptosis; Cells, Cultured; Cricetinae; Cricetulus; Culture Media, Serum-Free; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Fibroblasts; Isoenzymes; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53

1999
Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death.
    Cell death and differentiation, 1998, Volume: 5, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Etoposide; fas Receptor; HL-60 Cells; Humans; Jurkat Cells; Neoplasms; Oncogenes; Staurosporine

1998
Angiotensin II enhances the expression of Gialpha in A10 cells (smooth muscle): relationship with adenylyl cyclase activity.
    Archives of biochemistry and biophysics, 1999, May-01, Volume: 365, Issue:1

    Topics: Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cell Line; Colforsin; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Staurosporine

1999
Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells.
    Experimental cell research, 1999, Aug-25, Volume: 251, Issue:1

    Topics: Apoptosis; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspase 3; Caspases; Cell Nucleus; Cell Size; Cytochrome c Group; Dactinomycin; DNA Fragmentation; Enzyme Activation; Etoposide; Fluorescent Dyes; HL-60 Cells; Humans; Intracellular Membranes; Jurkat Cells; Membrane Potentials; Mitochondria; Oxidative Phosphorylation; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Staurosporine

1999
Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.
    Experimental neurology, 1999, Volume: 159, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Chloromethyl Ketones; Animals; bcl-2-Associated X Protein; Calcium; Caspases; Cell Death; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Cytosol; Dactinomycin; Dopamine; Dopamine Agents; Emetine; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Mesencephalon; Mice; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine

1999
Modes of L929 cell death induced by TNF-alpha and other cytotoxic agents.
    Cytokine, 1999, Volume: 11, Issue:10

    Topics: Animals; Annexin A5; Apoptosis; Azides; Cell Membrane; Cell Membrane Permeability; Cell Nucleus; Cell Size; Colchicine; Dactinomycin; DNA Fragmentation; Fluorescent Dyes; Kinetics; L Cells; Mice; Phosphatidylserines; Staurosporine; Tumor Necrosis Factor-alpha

1999
Inhibition of "tissue" transglutaminase increases cell survival by preventing apoptosis.
    The Journal of biological chemistry, 1999, Nov-26, Volume: 274, Issue:48

    Topics: Apoptosis; Calcimycin; Cell Death; Cell Survival; Cycloheximide; Dactinomycin; DNA, Antisense; Gene Expression Regulation, Enzymologic; Humans; Naphthalenes; RNA, Antisense; Staurosporine; Transcription, Genetic; Transfection; Transglutaminases; Tretinoin; Tumor Cells, Cultured

1999
Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cisplatin; Dactinomycin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glioblastoma; Humans; Nimustine; Staurosporine; Tumor Cells, Cultured

2000
Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.
    The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Ceramides; Culture Media, Serum-Free; Dactinomycin; Fibroblasts; Gene Deletion; Mice; Mice, Knockout; Radiation Tolerance; Radiation, Ionizing; Sphingomyelin Phosphodiesterase; Staurosporine; Tumor Necrosis Factor-alpha

2001
Expression of interleukin-4 in apoptotic cells: stimulation of the type-2 cytokine by different toxins in human peripheral blood mononuclear and tumor cells.
    Cytometry, 2000, Dec-01, Volume: 41, Issue:4

    Topics: Apoptosis; Brefeldin A; Caspase Inhibitors; Caspases; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Cycloheximide; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Humans; In Situ Nick-End Labeling; Interferon-gamma; Interleukin-4; Mitochondria; Oxidative Phosphorylation; Plant Preparations; Plant Proteins; Proto-Oncogene Proteins c-bcl-2; Ribosome Inactivating Proteins, Type 2; Staurosporine; T-Lymphocytes; Toxins, Biological; Tumor Cells, Cultured

2000
CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin-6 production.
    Blood, 2001, Jun-01, Volume: 97, Issue:11

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Dactinomycin; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Gene Expression; Genistein; Humans; Hyaluronan Receptors; Hyaluronic Acid; Immunoglobulin Fab Fragments; Interferon-gamma; Interleukin-6; Kinetics; Mice; Neutrophils; Protein Kinase Inhibitors; Rabbits; Receptors, Fc; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Transcription, Genetic

2001
Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis.
    Cell death and differentiation, 2001, Volume: 8, Issue:5

    Topics: Active Transport, Cell Nucleus; Apoptosis; Caspase Inhibitors; Caspases; Dactinomycin; DNA-Binding Proteins; Enzyme Activation; Female; HeLa Cells; Humans; Immunohistochemistry; Karyopherins; Microscopy, Fluorescence; Molecular Chaperones; Nuclear Envelope; Nuclear Pore; Nuclear Pore Complex Proteins; Nuclear Proteins; Permeability; Proto-Oncogene Proteins; ran GTP-Binding Protein; RNA, Messenger; Signal Transduction; Staurosporine

2001
Immunobiology of CD28 expression on human neutrophils. I. CD28 regulates neutrophil migration by modulating CXCR-1 expression.
    European journal of immunology, 2001, Volume: 31, Issue:5

    Topics: Adult; CD28 Antigens; Cells, Cultured; Chemotaxis, Leukocyte; Cross-Linking Reagents; Dactinomycin; Down-Regulation; Flow Cytometry; Gene Expression Regulation; Humans; Interleukin-8; Neutrophil Infiltration; Neutrophils; Receptors, Interleukin-8A; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

2001
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Adult; Aged; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Biomarkers; Biomarkers, Tumor; Chick Embryo; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; Dactinomycin; Enzyme Inhibitors; Extracellular Space; Female; Hematologic Neoplasms; Humans; Hydrogen Peroxide; Jurkat Cells; L Cells; L-Lactate Dehydrogenase; Male; Mice; Middle Aged; Mitochondria; Necrosis; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Protein Transport; Staurosporine; Tumor Necrosis Factor-alpha

2001
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2.
    The EMBO journal, 2001, Dec-03, Volume: 20, Issue:23

    Topics: Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Caspase Inhibitors; Caspases; Cell Line; Cytochrome c Group; Cytosol; Dactinomycin; Daunorubicin; DNA Damage; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Gamma Rays; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Kinetics; Microscopy, Fluorescence; Mitochondria; Mitochondrial Proteins; Models, Biological; Protein Binding; Protein Synthesis Inhibitors; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Subcellular Fractions; Time Factors; Tissue Distribution; Ultraviolet Rays

2001
Characterization of the increase in bone 66 kDa protein component with healing rat fractures: stimulatory effect of zinc.
    International journal of molecular medicine, 2002, Volume: 9, Issue:5

    Topics: Animals; Bone and Bones; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Estradiol; Flavonoids; Fracture Healing; Fractures, Bone; Insulin-Like Growth Factor I; Male; Parathyroid Hormone; Phosphoproteins; Rats; Rats, Wistar; Staurosporine; Time Factors; Transforming Growth Factor beta; Zinc

2002
Release of snRNP and RNA from transcription sites in adenovirus-infected cells.
    Experimental cell research, 2002, Jun-10, Volume: 276, Issue:2

    Topics: Adenoviridae; Cell Compartmentation; Cell Nucleus; Dactinomycin; DNA-Directed RNA Polymerases; Enzyme Inhibitors; Eukaryotic Cells; Gene Expression Regulation, Viral; HeLa Cells; Humans; Nucleic Acid Synthesis Inhibitors; Ribonucleoproteins, Small Nuclear; RNA; RNA Splicing; RNA, Messenger; RNA, Viral; Staurosporine; Temperature; Transcription, Genetic; Virus Replication

2002
Silkworm hemolymph as a potent inhibitor of apoptosis in Sf9 cells.
    Biochemical and biophysical research communications, 2002, Jul-26, Volume: 295, Issue:4

    Topics: Animals; Apoptosis; Bombyx; Camptothecin; Caspase 1; Caspases; Cell Line; Dactinomycin; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Hemolymph; Insecta; Mass Spectrometry; Protein Synthesis Inhibitors; Staurosporine; Time Factors

2002
Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression.
    Xenotransplantation, 2002, Volume: 9, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antigens, Heterophile; Apoptosis; Calcium; Cells, Cultured; Coculture Techniques; Cysteine Endopeptidases; Cytotoxicity, Immunologic; Dactinomycin; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; Fas Ligand Protein; Genes, bcl-2; Graft Rejection; Granzymes; Humans; Killer Cells, Natural; Macrolides; Membrane Glycoproteins; Microscopy, Electron; Necrosis; Perforin; Pore Forming Cytotoxic Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Serine Endopeptidases; Staurosporine; Swine; Tumor Necrosis Factor-alpha; Ubiquitin

2002
Nucleolus in apoptosis-induced mouse preimplantation embryos.
    Zygote (Cambridge, England), 2003, Volume: 11, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Blastocyst; Blastomeres; Camptothecin; Cell Nucleolus; Cell Survival; Chromosomal Proteins, Non-Histone; Dactinomycin; Female; Fluorescent Antibody Technique, Indirect; Mice; Mice, Inbred ICR; Nuclear Proteins; Nucleophosmin; Phosphoproteins; Pregnancy; Staurosporine

2003
EGF-Like domain of tenascin-C is proapoptotic for cultured smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carotid Arteries; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cricetinae; Cysteine Proteinase Inhibitors; Dactinomycin; Dipeptides; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mesocricetus; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligopeptides; Peptide Fragments; Protease Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Staurosporine; Tenascin

2004
Characterization of 4-O-methyl-ascochlorin-induced apoptosis in comparison with typical apoptotic inducers in human leukemia cell lines.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cycloheximide; Cytochromes c; Dactinomycin; DNA Fragmentation; fas Receptor; Fas-Associated Death Domain Protein; Humans; Immunoglobulin M; Jurkat Cells; Oligopeptides; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Terpenes

2004
Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Cell Nucleus; Chromatin; Cisplatin; Cytochromes c; Dactinomycin; DNA; DNA Damage; DNA Fragmentation; DNA Repair; Enzyme Activation; Flow Cytometry; HeLa Cells; Histones; Humans; Matrix Metalloproteinases; Membrane Potentials; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Mitochondria; Phosphatidylserines; Phosphorylation; Protein Binding; RNA, Small Interfering; Staurosporine; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53

2004
Phytoestrogens modulate prostaglandin production in bovine endometrium: cell type specificity and intracellular mechanisms.
    Experimental biology and medicine (Maywood, N.J.), 2005, Volume: 230, Issue:5

    Topics: Animals; Cattle; Dactinomycin; Endometrium; Epithelial Cells; Estradiol; Estrenes; Female; Glycine max; Oxytocin; Phytoestrogens; Prostaglandins; Pyrrolidinones; Staurosporine; Stromal Cells; Tetradecanoylphorbol Acetate

2005
Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide.
    Human reproduction (Oxford, England), 2005, Volume: 20, Issue:9

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Chlamydia trachomatis; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Ejaculation; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipopolysaccharides; Male; Protein Synthesis Inhibitors; Spermatozoa; Staurosporine; Substrate Specificity

2005
Cytochrome c is released in a single step during apoptosis.
    Cell death and differentiation, 2005, Volume: 12, Issue:5

    Topics: Apoptosis; Biomarkers; Cytochromes c; Dactinomycin; Enzyme Inhibitors; Green Fluorescent Proteins; HeLa Cells; Humans; Jurkat Cells; Kinetics; Ligands; Membrane Potentials; Microscopy, Video; Mitochondria; Protein Synthesis Inhibitors; Staurosporine; Temperature; Tumor Necrosis Factor-alpha; Ultraviolet Rays

2005
Cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis in human colorectal cancer cell line COLO 205; role of FLIP and metabolic inhibitors.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56 Suppl 3

    Topics: Apoptosis; Calcimycin; Calcium; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Survival; Chelating Agents; Colorectal Neoplasms; Cycloheximide; Dactinomycin; Drug Synergism; Edetic Acid; Egtazic Acid; Enzyme Activation; Enzyme Activators; Humans; Ionophores; Protein Kinase C; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Escape; Tumor Necrosis Factor-alpha

2005
T-cadherin protects endothelial cells from oxidative stress-induced apoptosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:12

    Topics: Adenoviridae; Androstadienes; Apoptosis; Cadherins; Caspases; Cell Survival; Cells, Cultured; Dactinomycin; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoblotting; Immunohistochemistry; Immunosuppressive Agents; MAP Kinase Signaling System; Microscopy, Fluorescence; Models, Biological; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction; Sirolimus; Staurosporine; Time Factors; Tumor Necrosis Factor-alpha; Wortmannin

2005
Equol and para-ethyl-phenol stimulate prostaglandin F(2alpha) secretion in bovine corpus luteum: intracellular mechanisms of action.
    Prostaglandins & other lipid mediators, 2006, Volume: 79, Issue:3-4

    Topics: Animals; Calcium; Cattle; Cells, Cultured; Corpus Luteum; Dactinomycin; Diet; Dinoprost; Equol; Estrenes; Female; Glycine max; Isoflavones; Luteinizing Hormone; Phenols; Phytoestrogens; Pyrrolidinones; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate

2006
Reduced apoptosis in human intestinal cells cured of persistent poliovirus infection.
    Journal of virology, 2007, Volume: 81, Issue:6

    Topics: Apoptosis; Caco-2 Cells; Cell Differentiation; Chronic Disease; Clone Cells; Dactinomycin; Disease Susceptibility; Enzyme Inhibitors; Humans; Intestines; Membrane Proteins; Nucleic Acid Synthesis Inhibitors; Poliomyelitis; Poliovirus; Receptors, Virus; Staurosporine

2007
A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:3

    Topics: Alkenes; Alkylation; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dactinomycin; Diploidy; DNA Fragmentation; DNA, Neoplasm; Enzyme Inhibitors; Lymphoma, T-Cell; Mice; Necrosis; Prodigiosin; Pyrroles; Rats; Sarcoma 180; Staurosporine; Tetrazolium Salts; Thiazoles

2008
Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.
    Oncogene, 2008, Feb-28, Volume: 27, Issue:10

    Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cell Line, Tumor; Dactinomycin; Enzyme Inhibitors; Genes, Reporter; Green Fluorescent Proteins; Humans; Mitochondria; Signal Transduction; Staurosporine; TNF-Related Apoptosis-Inducing Ligand

2008
Deoxysugars in bioactive natural products: development of novel derivatives by altering the sugar pattern.
    Current topics in medicinal chemistry, 2008, Volume: 8, Issue:8

    Topics: Biological Products; Dactinomycin; Deoxy Sugars; Multigene Family; Plasmids; Staurosporine

2008
A simultaneous release of SOD1 with cytochrome c regulates mitochondria-dependent apoptosis.
    Molecular and cellular biochemistry, 2009, Volume: 322, Issue:1-2

    Topics: Apoptosis; Cytochromes c; Dactinomycin; DNA Fragmentation; HL-60 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Staurosporine; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Voltage-Dependent Anion Channels

2009
Integrated microfluidic devices for combinatorial cell-based assays.
    Biomedical microdevices, 2009, Volume: 11, Issue:3

    Topics: Animals; Annexin A5; Antibiotics, Antineoplastic; Apoptosis; Bioreactors; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Equipment Design; Fibroblasts; Fibronectins; Genes, Reporter; Green Fluorescent Proteins; HeLa Cells; Humans; Melanoma, Experimental; Mice; Microfluidic Analytical Techniques; NIH 3T3 Cells; Staurosporine; Transcriptional Activation; Transfection

2009
Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells.
    International journal of oncology, 2012, Volume: 40, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptotic Protease-Activating Factor 1; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytochromes c; Dactinomycin; GTP Phosphohydrolases; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Membrane Proteins; Mitochondria; Molecular Chaperones; RNA Interference; Signal Transduction; Staurosporine; Thiolester Hydrolases; Time Factors; Transfection

2012
Staurosporine-induced differentiation of the RGC-5 cell line leads to apoptosis and cell death at the lowest differentiating concentration.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2012, Volume: 250, Issue:8

    Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 7; Cell Death; Cell Differentiation; Cell Proliferation; Cell Survival; Dactinomycin; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Retinal Ganglion Cells; RNA, Messenger; Staurosporine

2012
Individual dose and scheduling determine the efficacy of combining cytotoxic anticancer agents with a kinase inhibitor in non-small-cell lung cancer.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Antagonism; Drug Synergism; Etoposide; Humans; Immunoblotting; Lung Neoplasms; Paclitaxel; Protein Kinase C; Signal Transduction; Staurosporine; Time Factors

2012
Detection of apoptosis through the lipid order of the outer plasma membrane leaflet.
    Biochimica et biophysica acta, 2012, Volume: 1818, Issue:12

    Topics: Apoptosis; Camptothecin; Cell Line, Tumor; Cell Membrane; Cholesterol; Dactinomycin; Fluorescent Dyes; HeLa Cells; Humans; Lipid Bilayers; Lipids; Microscopy, Fluorescence; Oxazines; Spectrometry, Fluorescence; Sphingomyelins; Staurosporine

2012
Real-time cell viability assays using a new anthracycline derivative DRAQ7®.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2013, Volume: 83, Issue:2

    Topics: Anthracyclines; Apoptosis; Benzamides; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Dactinomycin; DNA Damage; Etoposide; Flow Cytometry; Fluorescent Dyes; Histones; Humans; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Nitrophenols; Piperazines; Rhodamines; Staurosporine; Sulfonamides; Sulfones

2013