dactinomycin has been researched along with spironolactone in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (42.11) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 11 (28.95) | 29.6817 |
| 2010's | 8 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Handler, JS; Keiser, HR; Zusman, RM | 1 |
| Kishikawa, T; Kugai, N; Nishiki, K; Ogata, E | 1 |
| Edelman, IS; Law, PY | 1 |
| Bittar, EE; Tallitsch, RB | 2 |
| Hayashi, T; Miyabo, S; Nakai, T | 1 |
| Ozaki, N; Suzuki, S; Takamura, S; Yoshida, J | 1 |
| Taylor, SG | 1 |
| Japundzić, I; Japundzić, M; Szabo, S | 1 |
| Benjamin, WB; Singer, I | 1 |
| Japundzić, I; Japurdzić, M; Mimić-Oka, J; Szabó, S | 1 |
| Greengard, P; Liu, AY | 1 |
| Leaf, A; Sharp, GW | 1 |
| Porter, GA | 1 |
| Garg, BD; Khandekar, JD; Kovacs, K; Tuchweber, B | 1 |
| Krajny, M; Solymoss, B; Varga, S; Werringloer, J | 1 |
| Chu, LL; Edelman, IS; Swaneck, GE | 1 |
| Asano, Y; Ebata, S; Kawakami, K; Muto, S; Nemoto, J | 1 |
| Amemiya, M; Asano, Y; Ebata, S; Muto, S; Nemoto, J; Okada, K; Saito, T | 1 |
| Harvey, BJ; Higgins, M | 1 |
| Asano, Y; Ebata, S; Muto, S; Okada, K; Saito, T | 1 |
| Albermann, L; Oberleithner, H; Schäfer, C; Shahin, V | 1 |
| Alzamora, R; Gonzalez, M; Marusic, ET; Michea, L | 1 |
| Abe, T; Arima, S; Ito, S; Kohagura, K; Satoh, F; Sugawara, A; Takeuchi, K; Xu, HL | 1 |
| Hansen, PB; Jensen, BL; Nørregaard, R; Schjerning, J; Skøtt, O; Sorensen, GL; Uhrenholt, TR | 1 |
| Duke, BJ; Eaton, DC; Holzman, JL; Kemendy, AE; Liu, L | 1 |
| Hopfer, U; Jose, PA; Pinho, MJ; Pinto, V; Soares-da-Silva, P | 1 |
| Leite-Dellova, DC; Malnic, G; Mello-Aires, M; Oliveira-Souza, M | 1 |
| de Mello-Aires, M; Leite-Dellova, D; Pergher, PS | 1 |
| Ehsan, A; Huang, PL; Iyer, LK; Jaffe, IZ; McGraw, AP; Mendelsohn, ME; Mohammad, NN; Newfell, BG; Rosano, G | 1 |
| James, RW; Mach, F; Maturana, AD; Pagano, S; Python, M; Rossier, MF; Roux-Lombard, P; Vuilleumier, N | 1 |
| Carretero, OA; D'Ambrosio, MA; Garvin, JL; Kutskill, K; Leung, P; Peterson, EL; Ren, Y; Wang, H | 1 |
| Kalamarz-Kubiak, H; Kleszczyńska, A; Kulczykowska, E | 1 |
2 review(s) available for dactinomycin and spironolactone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The stimulation of sodium transport by aldosterone.
Topics: Aldosterone; Animals; Binding Sites; Biological Transport, Active; Bufo marinus; Carbon Dioxide; Carbon Isotopes; Coenzyme A; Dactinomycin; Epithelial Cells; Epithelium; Glucose; Kidney; Mineralocorticoid Receptor Antagonists; Protein Binding; Protein Biosynthesis; Puromycin; Rats; Receptors, Drug; RNA; Sodium; Spironolactone; Stimulation, Chemical; Tritium; Urinary Bladder; Vasopressins | 1971 |
36 other study(ies) available for dactinomycin and spironolactone
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Effect of adrenal steroids on vasopressin-stimulated PGE synthesis and water flow.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Arachidonic Acids; Arginine Vasopressin; Body Water; Bufo marinus; Cycloheximide; Dactinomycin; Dexamethasone; In Vitro Techniques; Progesterone; Prostaglandins E; Sodium; Spironolactone; Triamcinolone; Urinary Bladder; Vasopressins | 1978 |
Oxidative response to aldosterone of pyridine nucleotide in rat kidney in situ.
Topics: Adenine Nucleotides; Aldosterone; Animals; Calcitonin; Cycloheximide; Dactinomycin; Desoxycorticosterone; Dexamethasone; Dinitrophenols; Dose-Response Relationship, Drug; Energy Metabolism; Glycyrrhetinic Acid; Hemorrhage; Kidney; Male; Malonates; NAD; Ouabain; Oxidation-Reduction; Pyruvates; Rats; Rotenone; Spironolactone; Water | 1977 |
Effect of aldosterone on incorporation of amino acids into renal medullary proteins.
Topics: Adrenalectomy; Aldosterone; Amino Acids; Animals; Calcium; Cytosol; Dactinomycin; Dexamethasone; Kidney; Kidney Medulla; Leucine; Male; Methionine; Mineralocorticoid Receptor Antagonists; Proteins; Rats; RNA; Sodium; Spironolactone | 1978 |
Stimulation by aldosterone of the sodium efflux in barnacle muscle fibres: effects of RNA inhibitors and spironolactone.
Topics: Aldosterone; Amanitins; Animals; Biological Transport; Dactinomycin; Deoxyadenosines; Dose-Response Relationship, Drug; In Vitro Techniques; Muscles; Sodium; Spironolactone; Thoracica | 1975 |
Mode of stimulation by aldosterone of the sodium efflux in barnacle muscle fibres: effects of ouabain, ethacrynic acid, diphenylhydantoin, (ATPMg)(2-), adenine translocase inhibitors, pyruvate and oxythiamine.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Atractyloside; Biological Transport, Active; Bongkrekic Acid; Dactinomycin; Ethacrynic Acid; In Vitro Techniques; Muscles; Ouabain; Oxythiamine; Phenytoin; Phosphatidylserines; Pyruvates; Sodium; Spironolactone; Stimulation, Chemical | 1976 |
Glucocorticoids increase Ca2+ uptake and [3H]dihydropyridine binding in A7r5 vascular smooth muscle cells.
Topics: Amiloride; Analysis of Variance; Androstanols; Animals; Calcium; Calcium Channels; Cell Count; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Dihydropyridines; Electric Conductivity; Glucocorticoids; Indomethacin; Kinetics; Muscle, Smooth, Vascular; Potassium; Proteins; Rats; Receptors, Glucocorticoid; Spironolactone; Water | 1991 |
Effect of aldosterone antagonists on aldosterone-induced activation of Mg2+ -HCO3- -ATPase and carbonic anhydrase in rat intestinal mucosa.
Topics: Adenosine Triphosphatases; Adrenalectomy; Aldosterone; Animals; Ca(2+) Mg(2+)-ATPase; Canrenoic Acid; Carbonic Anhydrases; Dactinomycin; Duodenum; Enzyme Activation; Intestinal Mucosa; Jejunum; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Spironolactone | 1985 |
Common medical problems in disseminated cancer.
Topics: Androgens; Brain Neoplasms; Chlorothiazide; Dactinomycin; Estrogens; Humans; Hypercalcemia; Lymphedema; Methotrexate; Neoplasm Metastasis; Pain Management; Palliative Care; Pleural Effusion; Prednisolone; Spinal Cord Compression; Spironolactone | 1970 |
Induction of ethylmorphine demethylation and aniline p-hydroxylation by various catatoxic steroids in regenerating rat liver.
Topics: Androstenols; Aniline Compounds; Animals; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Hepatectomy; Ketosteroids; Liver; Liver Regeneration; Mixed Function Oxygenases; Morphinans; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Propionates; Rats; Spectrophotometry; Spironolactone; Steroids; Steroids, Fluorinated; Time Factors | 1974 |
Aldosterone-induced protein in toad urinary bladder.
Topics: Aldosterone; Animals; Biological Transport, Active; Bufo marinus; Dactinomycin; In Vitro Techniques; Insulin; Kinetics; Membrane Potentials; Methionine; Mineralocorticoid Receptor Antagonists; Molecular Weight; Peptide Biosynthesis; Protein Biosynthesis; Sodium; Spironolactone; Stimulation, Chemical; Sulfur Radioisotopes; Urinary Bladder | 1974 |
Influence of spironolactone and dexamethasone on phosphoprotein phosphatase in the rat liver, kidney and spleen.
Topics: Animals; Caseins; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Female; Kidney; Liver; Microsomes; Phosphoproteins; Phosphoric Monoester Hydrolases; Proadifen; Rats; Spironolactone; Spleen | 1972 |
Aldosterone-induced increase in protein phosphatase activity of toad bladder.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Autoradiography; Bufo marinus; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Activation; In Vitro Techniques; Microsomes; Mineralocorticoid Receptor Antagonists; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Proteins; Puromycin; Spironolactone; Urinary Bladder | 1974 |
The action of aldosterone on transepithelial sodium transport in isolated ventral toad skin.
Topics: Aldosterone; Animals; Anura; Biological Transport, Active; Cycloheximide; Dactinomycin; Depression, Chemical; Electrophysiology; Glucose; Hexoses; In Vitro Techniques; Ouabain; Skin Physiological Phenomena; Sodium; Spironolactone; Stimulation, Chemical | 1971 |
Influence of dactinomycin on the ultrastructural changes induced in rat hepatocytes by spironolactone and pregnelonone-16 -carbonitrile.
Topics: Animals; Dactinomycin; Endoplasmic Reticulum; Female; Injections, Intravenous; Liver; Nitriles; Pregnenolone; Rats; Spironolactone | 1971 |
Suppression by nucleic acid- and protein-synthesis inhibitors of drug detoxication induced by spironolactone or ethylestrenol.
Topics: Anesthesia; Animals; Antimetabolites; Chloramphenicol; Cycloheximide; Dactinomycin; Ethylestrenol; Female; Mercaptopurine; Pentobarbital; Protein Biosynthesis; Puromycin; Rats; RNA; Spironolactone | 1970 |
Stereospecific binding of aldosterone to renal chromatin.
Topics: Aldosterone; Animals; Binding Sites; Centrifugation, Density Gradient; Chymotrypsin; Dactinomycin; Deoxyribonucleases; Drug Stability; Estradiol; Fludrocortisone; Glycerol; Hydrocortisone; Kidney; Male; Metabolism; Mineralocorticoids; Nucleoproteins; Progesterone; Protein Binding; Rats; Ribonucleases; Spironolactone; Tritium; Trypsin | 1970 |
Corticosterone and 11-dehydrocorticosterone stimulate Na,K-ATPase gene expression in vascular smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; Corticosterone; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Mifepristone; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1998 |
Aldosterone activates Na+/H+ exchange in vascular smooth muscle cells by nongenomic and genomic mechanisms.
Topics: Aldosterone; Animals; Aorta, Thoracic; Cells, Cultured; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Hormone Antagonists; Hydrogen-Ion Concentration; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sodium-Hydrogen Exchangers; Spironolactone; Transcription, Genetic | 1999 |
Nongenomic effects of aldosterone on Ca2+ in M-1 cortical collecting duct cells.
Topics: Aldosterone; Animals; Biological Transport; Calcium; Cell Line; Dactinomycin; Enzyme Inhibitors; Genome; Intracellular Membranes; Kidney Cortex; Kidney Tubules, Collecting; Mice; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; Nucleic Acid Synthesis Inhibitors; Osmolar Concentration; Ouabain; Protein Kinase C; Sodium; Spironolactone | 2000 |
Glucocorticoid modulates Na+/H+ exchange activity in vascular smooth muscle cells by nongenomic and genomic mechanisms.
Topics: Animals; Cells, Cultured; Corticosterone; Cycloheximide; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Genome; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Mifepristone; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Steroid; RNA, Messenger; Sodium-Hydrogen Exchangers; Spironolactone | 2000 |
Route of steroid-activated macromolecules through nuclear pores imaged with atomic force microscopy.
Topics: Aldosterone; Animals; Calcium; Cell Nucleus; Chelating Agents; Dactinomycin; Electrophysiology; Microscopy, Atomic Force; Mineralocorticoid Receptor Antagonists; Models, Biological; Nuclear Pore; Nucleic Acid Synthesis Inhibitors; Receptors, Mineralocorticoid; Ribonuclease, Pancreatic; Spironolactone; Steroids; Time Factors; Xenopus | 2003 |
Nongenomic effect of aldosterone on Na+,K+-adenosine triphosphatase in arterial vessels.
Topics: Aldosterone; Animals; Aorta, Thoracic; Catalytic Domain; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Eplerenone; Indoles; Ionophores; Male; Maleimides; Mineralocorticoid Receptor Antagonists; Monensin; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase; Spironolactone; Transcription, Genetic | 2003 |
Nongenomic vascular action of aldosterone in the glomerular microcirculation.
Topics: Aldosterone; Animals; Arterioles; Calcium Channel Blockers; Capillaries; Cycloheximide; Dactinomycin; Endothelium, Vascular; In Vitro Techniques; Kidney Glomerulus; Male; Mineralocorticoid Receptor Antagonists; Neomycin; Protein Synthesis Inhibitors; Rabbits; Spironolactone; Vascular Resistance; Vasoconstriction | 2003 |
Rapid inhibition of vasoconstriction in renal afferent arterioles by aldosterone.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Aorta; Arterioles; Benzoquinones; Calcium; Cells, Cultured; Chromones; Dactinomycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Heart Ventricles; Humans; In Vitro Techniques; Kidney; Lactams, Macrocyclic; Male; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinones; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Vasoconstriction | 2003 |
Transactivation of the IGF-1R by aldosterone.
Topics: Aldosterone; Animals; Cell Line; Dactinomycin; Epithelial Cells; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Kidney; Mifepristone; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptor, Insulin; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Transcriptional Activation; Xenopus laevis; Xenopus Proteins | 2007 |
Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.
Topics: Aldosterone; Amiloride; Animals; Cell Line; Cytochalasin B; Dactinomycin; Gene Expression Regulation; Genome; Guanidines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunoblotting; Kidney Tubules, Proximal; Methacrylates; Mifepristone; Oxidative Stress; Protein Isoforms; Rats; Rats, Inbred SHR; Receptors, Mineralocorticoid; RNA, Messenger; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2008 |
Genomic and nongenomic dose-dependent biphasic effect of aldosterone on Na+/H+ exchanger in proximal S3 segment: role of cytosolic calcium.
Topics: Aldosterone; Ammonium Chloride; Animals; Calcium; Calcium Signaling; Cycloheximide; Cytosol; Dactinomycin; Gene Expression; Guanidines; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Male; Methacrylates; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2008 |
Direct action of aldosterone on bicarbonate reabsorption in in vivo cortical proximal tubule.
Topics: Aldosterone; Animals; Bicarbonates; Cycloheximide; Dactinomycin; Hydrogen-Ion Concentration; Kidney Cortex; Kidney Tubules, Proximal; Male; Microelectrodes; Mineralocorticoid Receptor Antagonists; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Spironolactone | 2009 |
Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways.
Topics: Aldosterone; Animals; Aorta; Atherosclerosis; Cells, Cultured; Dactinomycin; Endothelium, Vascular; Gene Expression Profiling; Gene Expression Regulation; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Myocytes, Smooth Muscle; Oxidative Stress; RNA, Messenger; Spironolactone | 2011 |
Antiapolipoprotein A-1 IgG chronotropic effects require nongenomic action of aldosterone on L-type calcium channels.
Topics: Aldosterone; Animals; Animals, Newborn; Apolipoprotein A-I; Calcium Channels, L-Type; Cells, Cultured; Dactinomycin; Electrophysiology; Eplerenone; Immunoglobulin G; Myocytes, Cardiac; Oxidation-Reduction; Oxygen; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone; Time Factors | 2012 |
Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30.
Topics: Aldosterone; Amiloride; Animals; Arterioles; Cycloheximide; Dactinomycin; Epithelial Sodium Channels; Eplerenone; Feedback; Kidney Tubules; Male; Rabbits; Receptors, G-Protein-Coupled; Receptors, Mineralocorticoid; Spironolactone | 2014 |
Cortisol stimulates arginine vasotocin and isotocin release from the hypothalamo-pituitary complex of round goby (Neogobius melanostomus): Probable mechanisms of action.
Topics: Animals; Dactinomycin; Female; Hydrocortisone; Hypothalamus; In Vitro Techniques; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Oxytocin; Perciformes; Pituitary Gland; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Vasotocin | 2015 |