dactinomycin and propylthiouracil

dactinomycin has been researched along with propylthiouracil in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gabrielsen, AE1
D'Angelo, SA; Lombardi, DM; Paul, DH; Wall, NR1
Carrington, H; Herrera, A; Williams, MT1
Braverman, LE; Foster, AE; Ingbar, SH; Vagenakis, AG1
Bakke, JL; Lawrence, N1
Bargoni, N1
Cavallo, F; Coghe, M; Grillo, MA1
Halmi, NS; Polly, RE; Westra, JP1
Imura, H; Inada, M; Ishii, H; Kuma, K; Mashio, Y; Matsuzuka, F; Naito, K; Nishikawa, M; Tanaka, K1
Dickstein, Y; Gordon, A; Gross, J; Schwartz, H1
Bottazzi, C; Demori, I; Fugassa, E1
Beneduce, L; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Pinna, G; Silvestri, E1
GOLDBERG, IH; SEED, RW1
Biswas, A; De, J; Kundu, S; Pramanik, M; Ray, AK; Roy, S1

Reviews

1 review(s) available for dactinomycin and propylthiouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for dactinomycin and propylthiouracil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
The nature of lupus erythematosus in mice.
    Cutis, 1979, Volume: 23, Issue:4

    Topics: Animals; Antigen-Antibody Complex; Dactinomycin; Disease Models, Animal; Female; Lupus Erythematosus, Systemic; Mice; Propylthiouracil; Rodent Diseases; Vincristine

1979
Pituitary thyrotropin (TSH) rebound phenomenon and kinetics of secretion in the goitrous rat: differential effects of thyroxine on synthesis and release of TSH.
    Endocrinology, 1976, Volume: 99, Issue:4

    Topics: Animals; Dactinomycin; Female; Goiter; Kinetics; Metabolic Clearance Rate; Pituitary Gland; Pituitary Gland, Anterior; Propylthiouracil; Puromycin; Rats; Secretory Rate; Thyroid Gland; Thyrotropin; Thyroxine; Uridine

1976
Stimulation of mouse liver glutathione S-transferase activity in propylthiouracil-treated mice in vivo by tri-iodothyronine.
    The Biochemical journal, 1986, Jan-15, Volume: 233, Issue:2

    Topics: Animals; Dactinomycin; Enzyme Induction; Epoxy Compounds; Female; Glutathione Transferase; Hypothyroidism; Liver; Mice; Mice, Inbred C57BL; Nitrophenols; Propylthiouracil; Triiodothyronine

1986
Stimulatory effect of 5-fluorouracil on thyroid serum iodide concentration ratios in the rat.
    Endocrinology, 1971, Volume: 88, Issue:5

    Topics: Animals; Dactinomycin; Female; Fluorouracil; Iodides; Iodine Isotopes; Iodoproteins; Male; Propylthiouracil; Rats; Stimulation, Chemical; Thyroid Gland

1971
The effect of actinomycin-D on TSH formation, release and inhibition by thyroxin.
    European journal of pharmacology, 1968, Volume: 2, Issue:4

    Topics: Animals; Cattle; Dactinomycin; Depression, Chemical; Drug Antagonism; Hypothyroidism; Male; Pituitary Gland; Propylthiouracil; Rats; RNA, Messenger; Starvation; Thyroid Gland; Thyrotropin; Thyroxine

1968
[Aspects of control of thyroid hormones on metabolism].
    Bulletin de la Societe de chimie biologique, 1968, Volume: 50, Issue:12

    Topics: Animals; Carbohydrate Metabolism; Cycloheximide; Dactinomycin; Enterobacter; Ethionine; Fasting; Glucosephosphate Dehydrogenase; Glycolysis; Hexosephosphates; Insulin; Kidney; Kinetics; Lactates; Liver; Malate Dehydrogenase; Muscles; Propylthiouracil; Puromycin; Rabbits; Rats; RNA; Saccharomyces; Thyroid Hormones

1968
Effect of thyroid hormones on some enzymes of nitrogen metabolism.
    Enzymologia, 1968, Dec-31, Volume: 35, Issue:6

    Topics: Ammonia; Animals; Antithyroid Agents; Aspartic Acid; Dactinomycin; Depression, Chemical; Diet; Ethionine; Glutaminase; Glutamine; Hyperthyroidism; Hypothyroidism; Kidney; Ligases; Liver; Male; Ornithine; Phosphotransferases; Propylthiouracil; Puromycin; Rats; Stimulation, Chemical; Thyroid Hormones; Transaminases; Transferases; Urea

1968
Some effects of actinomycin D on iodine metabolism in the rat thyroid.
    Endocrinology, 1966, Volume: 79, Issue:2

    Topics: Animals; Dactinomycin; Hypophysectomy; Iodine; Iodine Isotopes; Propylthiouracil; Rats; Thyroid Gland; Thyrotropin; Triiodothyronine

1966
Induction of outer and inner ring monodeiodinases in human thyroid gland by thyrotropin.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:3

    Topics: Bucladesine; Culture Techniques; Dactinomycin; Enzyme Induction; Graves Disease; Humans; Iodide Peroxidase; Kinetics; Peroxidases; Propylthiouracil; Theophylline; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1983
The metabolism of T4 and T3 in cultured chick-embryo heart cells.
    Molecular and cellular endocrinology, 1980, Volume: 20, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Heart; Myocardium; Propylthiouracil; Thyroxine; Triiodothyronine

1980
Tri-iodothyronine increases insulin-like growth factor binding protein-2 expression in cultured hepatocytes from hypothyroid rats.
    The Journal of endocrinology, 1999, Volume: 161, Issue:3

    Topics: Animals; Anisomycin; Blotting, Northern; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression; Hypothyroidism; Insulin-Like Growth Factor Binding Protein 2; Liver; Male; Methimazole; Propylthiouracil; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Triiodothyronine

1999
Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?
    Endocrinology, 2002, Volume: 143, Issue:2

    Topics: Animals; Antithyroid Agents; Basal Metabolism; Dactinomycin; Diiodothyronines; Enzyme Inhibitors; Hypothyroidism; Iodide Peroxidase; Iopanoic Acid; Liver; Male; Propylthiouracil; Protein Synthesis Inhibitors; Radioimmunoassay; Rats; Rats, Wistar; Thyroid Gland; Triiodothyronine

2002
BIOSYNTHESIS OF THYROGLOBULIN. II. ROLE OF SUBUNITS, IODINATION, AND RIBONUCLEIC ACID SYNTHESIS.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Amino Acids; Animals; Dactinomycin; Halogenation; Iodine Isotopes; Leucine; Metabolism; Pharmacology; Propylthiouracil; Proteins; Puromycin; Research; RNA; Sheep; Thyroglobulin; Thyroid Gland; Thyrotropin; Tritium; Ultracentrifugation

1965
Maintenance of homeostasis for thyroid hormone in the adult rat brain: possible involvement of a nuclear-mediated phenomenon.
    Neuroendocrinology, 2007, Volume: 86, Issue:2

    Topics: Acetylcholinesterase; Age Factors; Animals; Antithyroid Agents; Cell Nucleus; Cerebral Cortex; Cyclic AMP; Cycloheximide; Dactinomycin; Homeostasis; Hypothyroidism; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Propylthiouracil; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Thyroxine; Triiodothyronine

2007