dactinomycin and proflavine

dactinomycin has been researched along with proflavine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199028 (87.50)18.7374
1990's3 (9.38)18.2507
2000's0 (0.00)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Denny, WA; Feigon, J; Kearns, DR; Leupin, W1
Herdewijn, P; Maiti, M; Nauwelaerts, K1
Seto, H; Tomasz, A1
Moscona, AA; Sarkar, PK1
Bearden, J; Haidle, CW1
Neidle, S1
Abbott, MT; Griswold, WR; Madrid, VO; Pugh, CS; Shaffer, PM; Tappen, DC1
Dimmock, NJ; Minor, PD1
Chiu, CS; Flanegan, JB; Greenberg, GR1
Chao, L1
Crothers, DM; Dattagupta, N; Hogan, M1
Ekblom, P; Lehtonen, E; Nordling, S; Saxén, L; Wartiovaara, J1
Giessner-Prettre, C; Pullman, B1
Hentschel, CC; Tata, JR1
Chan, H; Recher, L; Sykes, JA1
Khandjian, EW; Turian, G1
Benkert, B; Garbrecht, M; Mertelsmann, R; Neth, R1
Bláha, K; Fric, I; Sponar, J1
Clark, S; Jost, E1
Walter, Z; Wiszkowska, H1
Allfrey, VG; Chen, TA; Cozzolino, A; Sterner, R1
Doerr, CL; Harrington-Brock, K; Moore, MM1
Baldini, G; Varani, G1
Baldini, G; Della Torre, L; Varani, G1
Abraham, Z; Neidle, S1
Ashmarin, IP; Fedorova, TM1
Goppelt, M; Haupt, W; Langowski, J; Maass, G; Mayer, H; Pingoud, A; Urbanke, C1
Attardi, G; Gaines, G1
Kearns, DR; Mirau, PA1
HARTMANN, G; LIERSCH, M1
ALEXANDER, M; FURTH, JJ; HURWITZ, J; MALAMY, M1

Reviews

2 review(s) available for dactinomycin and proflavine

ArticleYear
The molecular basis for the action of some DNA-binding drugs.
    Progress in medicinal chemistry, 1979, Volume: 16

    Topics: Acridines; Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Dactinomycin; Daunorubicin; DNA; Ellipticines; Ethidium; Intercalating Agents; Lucanthone; Models, Chemical; Proflavine

1979
Structural and sequence-dependent aspects of drug intercalation into nucleic acids.
    CRC critical reviews in biochemistry, 1984, Volume: 17, Issue:1

    Topics: Base Sequence; Chemical Phenomena; Chemistry, Physical; Dactinomycin; Daunorubicin; DNA Restriction Enzymes; Echinomycin; Ethidium; Intercalating Agents; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acids; Proflavine; Structure-Activity Relationship; X-Ray Diffraction

1984

Other Studies

30 other study(ies) available for dactinomycin and proflavine

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship

1984
Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing.
    Bioorganic & medicinal chemistry letters, 2012, Feb-15, Volume: 22, Issue:4

    Topics: Aminoglycosides; Antineoplastic Agents; Base Sequence; DEAD-box RNA Helicases; Humans; MicroRNAs; Models, Biological; Molecular Sequence Data; Ribonuclease III; RNA Processing, Post-Transcriptional

2012
Inhibitors of genetic recombination in pneumococci.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:1

    Topics: Dactinomycin; Daunorubicin; DNA, Bacterial; Ethidium; Proflavine; Recombination, Genetic; Streptococcus pneumoniae; Transformation, Genetic

1977
Glutamine synthetase induction in embryonic neural retina. Interactions of receptor-hydrocortisone complexes with cell nuclei.
    Differentiation; research in biological diversity, 1977, Jan-14, Volume: 7, Issue:2

    Topics: Animals; Cell Nucleus; Chick Embryo; Cytosol; Dactinomycin; Enzyme Induction; Glutamate-Ammonia Ligase; Hydrocortisone; Kinetics; Proflavine; Protein Biosynthesis; Receptors, Glucocorticoid; Receptors, Steroid; Retina

1977
Stimulation of bleomycin-induced fragmentation of DNA by intercalating agents.
    Biochemical and biophysical research communications, 1975, Jul-08, Volume: 65, Issue:1

    Topics: Bacillus subtilis; Binding Sites; Bleomycin; Centrifugation, Density Gradient; Dactinomycin; DNA, Bacterial; Escherichia coli; Ethidium; Kinetics; Mercaptoethanol; Molecular Weight; Proflavine; Pronase

1975
Regulation of thymidine metabolism in Neurospora crassa.
    Journal of bacteriology, 1976, Volume: 125, Issue:3

    Topics: Carbon Dioxide; Carboxy-Lyases; Cell-Free System; Dactinomycin; Enzyme Induction; Mixed Function Oxygenases; Mutation; Neurospora; Neurospora crassa; Proflavine; Quaternary Ammonium Compounds; Ribose; Temperature; Thymidine; Thymine

1976
Selective inhibition of influenza virus protein synthesis by inhibitors of DNA function.
    Virology, 1977, May-15, Volume: 78, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Camptothecin; Cell Line; Dactinomycin; Daunorubicin; Echinomycin; Ethidium; Hemagglutinins, Viral; Influenza A virus; Neuraminidase; Newcastle disease virus; Nogalamycin; Plicamycin; Proflavine; Viral Proteins; Virus Replication

1977
Inhibitory effect of agents altering the structure of DNA on the synthesis of pyrimidine deoxyribonucleotides in bacteriophage T4 DNA replication.
    The Journal of biological chemistry, 1977, Sep-10, Volume: 252, Issue:17

    Topics: Coliphages; Cytosine; Dactinomycin; Deoxyribonucleotides; DNA Replication; DNA, Viral; Escherichia coli; Ethidium; Kinetics; Methyl Methanesulfonate; Mitomycins; Proflavine; Pyrimidine Nucleotides; Ultraviolet Rays

1977
Regulation of RNA polymerase subunit synthesis in Escherichia coli: utilization of DNA-Intercalating drugs as a probe.
    Archives of biochemistry and biophysics, 1977, Volume: 183, Issue:1

    Topics: Acridines; Bacterial Proteins; Berberine; Berberine Alkaloids; Dactinomycin; DNA-Directed RNA Polymerases; Escherichia coli; Ethidium; Peptide Fragments; Proflavine; Rifampin; RNA, Bacterial; RNA, Messenger; Uridine

1977
Transient electric dichroism studies of the structure of the DNA complex with intercalated drugs.
    Biochemistry, 1979, Jan-23, Volume: 18, Issue:2

    Topics: Acridines; Animals; Cattle; Chemical Phenomena; Chemistry; Dactinomycin; DNA; Ethidium; Nucleic Acid Conformation; Proflavine; Spectrometry, Fluorescence; Spectrophotometry; Thymus Gland

1979
Metabolic inhibitors and kidney tubule induction.
    Medical biology, 1978, Volume: 56, Issue:6

    Topics: Animals; Cell Differentiation; Cycloheximide; Cytoplasm; Dactinomycin; DNA; Embryonic Induction; Ethidium; Kidney Tubules; Macromolecular Substances; Mice; Micropore Filters; Mitomycins; Proflavine; Protein Biosynthesis; RNA; Spinal Cord

1978
[Proton isoshielding curves of several nucleic acid intercalating agents].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1976, Sep-27, Volume: 283, Issue:6

    Topics: Biophysical Phenomena; Biophysics; Dactinomycin; Ethidium; Molecular Conformation; Nucleic Acids; Proflavine; Protons; Quinacrine

1976
Differential activation of free and template-engaged RNA polymerase I and II during the resumption of development of dormant Artemia gastrulae.
    Developmental biology, 1977, Volume: 57, Issue:2

    Topics: Age Factors; Animals; Cell Nucleus; Dactinomycin; Decapoda; DNA-Directed RNA Polymerases; Heparin; Hibernation; Kinetics; Proflavine; RNA; RNA Polymerase I; RNA Polymerase II; Templates, Genetic

1977
Further studies on the mammalian cell nucleolus.
    Journal of ultrastructure research, 1976, Volume: 56, Issue:2

    Topics: Adenosine; Camptothecin; Cell Line; Cell Nucleolus; Chromatin; Dactinomycin; Hypertonic Solutions; Organoids; Proflavine

1976
Release of RNA--DNA-protein complex during differentiation of the water mould Allomyces arbuscula.
    Cell differentiation, 1976, Volume: 5, Issue:3

    Topics: Cell Differentiation; Centrifugation, Density Gradient; Chromatography; Chytridiomycota; Cycloheximide; Dactinomycin; Deoxyribonucleases; Deoxyribonucleoproteins; DNA; Fungal Proteins; Fungi; Nucleoproteins; Proflavine; Ribonucleases; Ribonucleoproteins; RNA

1976
[The effect of actinomycin d, acridine dyes and related substances on the biosynthesis of nucleic acids in normal and leukemic white blood cells. Comparative investigation in intact cells and in a cell-free system (author's transl)].
    Klinische Wochenschrift, 1975, Aug-15, Volume: 53, Issue:16

    Topics: Acridines; Animals; Cell Membrane; Cell-Free System; Cells, Cultured; Dactinomycin; DNA; DNA-Directed RNA Polymerases; DNA, Neoplasm; Friend murine leukemia virus; Humans; Leukemia; Leukocytes; Mice; Nucleic Acids; Proflavine; RNA; RNA, Neoplasm; Subcellular Fractions; Thymidine; Tritium; Uridine

1975
Basic polypeptides as histone models: circular dichroism of complexes of model polypeptides with DNA.
    Biophysical chemistry, 1975, Volume: 3, Issue:3

    Topics: Binding Sites; Circular Dichroism; Dactinomycin; DNA; Histones; Kinetics; Macromolecular Substances; Molecular Weight; Nucleic Acid Conformation; Peptides; Proflavine; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet

1975
Binding and arrangement of non-histone proteins in chromatin-like structures from mammalian cells.
    FEBS letters, 1975, Dec-01, Volume: 60, Issue:1

    Topics: Acridines; Binding Sites; Chromatin; Dactinomycin; Deoxyribonucleoproteins; DNA; Ethidium; Histones; Nucleic Acid Conformation; Nucleoproteins; Proflavine; Structure-Activity Relationship

1975
Effect of malathion on the initiation and elongation steps of transcription.
    Acta biochimica Polonica, 1990, Volume: 37, Issue:1

    Topics: Animals; Cell Nucleus; Dactinomycin; Kinetics; Malathion; Proflavine; Swine; Thymus Gland; Transcription, Genetic

1990
Reversible and irreversible changes in nucleosome structure along the c-fos and c-myc oncogenes following inhibition of transcription.
    Journal of molecular biology, 1990, Apr-05, Volume: 212, Issue:3

    Topics: Amanitins; Animals; Cell Line; Chromatography, Affinity; Dactinomycin; DNA; Mice; Mice, Inbred BALB C; Molecular Conformation; Nucleosomes; Proflavine; Proto-Oncogenes; RNA Polymerase II; Transcription, Genetic

1990
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
    Mutation research, 1989, Volume: 222, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoacridines; Amsacrine; Animals; Bleomycin; Chromosome Aberrations; Dactinomycin; Dimethyl Sulfoxide; DNA Damage; Doxorubicin; Hazardous Waste; Leukemia L5178; Leukemia, Experimental; Methylcholanthrene; Methylmethacrylate; Methylmethacrylates; Mice; Micronucleus Tests; Mutation; Nitrogen Mustard Compounds; Proflavine; Thymidine Kinase

1989
Solvation effects and the mechanism of drug-DNA binding.
    Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9

    Topics: Alcohols; Dactinomycin; DNA; Ethidium; In Vitro Techniques; Proflavine; Propidium; Solvents

1988
Nonspecific interactions in dye binding to DNA. Influence of alcohols and amides.
    Biophysical chemistry, 1987, Volume: 28, Issue:3

    Topics: Alcohols; Amides; Coloring Agents; Dactinomycin; DNA; Ethidium; Intercalating Agents; Kinetics; Proflavine; Propidium

1987
[DNA-tropic inhibitors of nuclease action on DNA in liver nuclei].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:7

    Topics: Animals; Bleomycin; Carubicin; Cell Nucleus; Chromomycins; Dactinomycin; Deoxyribonucleases; Distamycins; Ethidium; In Vitro Techniques; Liver; Proflavine; Rats

1980
The effect of several nucleic acid binding drugs on the cleavage of d(GGAATTCC) and pBR 322 by the Eco RI restriction endonuclease.
    Nucleic acids research, 1981, Nov-25, Volume: 9, Issue:22

    Topics: Circular Dichroism; Dactinomycin; Distamycins; DNA Restriction Enzymes; Ethidium; Kinetics; Mathematics; Molecular Conformation; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Plasmids; Proflavine

1981
Intercalating drugs and low temperatures inhibit synthesis and processing of ribosomal RNA in isolated human mitochondria.
    Journal of molecular biology, 1984, Feb-05, Volume: 172, Issue:4

    Topics: Dactinomycin; DNA, Mitochondrial; Ellipticines; Ethidium; HeLa Cells; Humans; Intercalating Agents; Mitochondria; Proflavine; RNA Processing, Post-Transcriptional; RNA, Ribosomal; Temperature; Transcription, Genetic

1984
The effect of intercalating drugs on the kinetics of the B to Z transition of poly(dG-dC).
    Nucleic acids research, 1983, Mar-25, Volume: 11, Issue:6

    Topics: Dactinomycin; Ethidium; Intercalating Agents; Kinetics; Nucleic Acid Conformation; Polydeoxyribonucleotides; Proflavine

1983
[THE BONDING OF PROFLAVIN AND ACTINOMYCIN TO DESOXYRIBONUCLEIC ACID. I. THE INFLUENCE OF ION STRENGTH AND PH AS WELL AS THE EFFECTS OF UREA ON THE BONDING].
    Biochemische Zeitschrift, 1964, Sep-28, Volume: 340

    Topics: Acridines; Dactinomycin; DNA; Object Attachment; Osmolar Concentration; Proflavine; Research; Urea

1964
The role of deoxyribonucleic acid in ribonucleic acid synthesis. III. The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin.
    Proceedings of the National Academy of Sciences of the United States of America, 1962, Jul-15, Volume: 48

    Topics: Biochemical Phenomena; Dactinomycin; DNA; Flavins; Proflavine; RNA

1962