dactinomycin and podophyllotoxin

dactinomycin has been researched along with podophyllotoxin in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199024 (77.42)18.7374
1990's4 (12.90)18.2507
2000's1 (3.23)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Soloway, MS1
Dombernowsky, P; Nissen, NI1
Albain, KS; Le Beau, MM; Schumacher, H; Ullirsch, R1
Aristoff, PA; Fisher, JF1
Newlands, ES1
Bearden, JD; Caldwell, RD; Case, LD; Cooper, MR; Jackson, DV; Muss, HB; Nelson, EC; Powell, BL; Richards, F; Zekan, PJ1
de Camargo, B; Lederman, H; Pinus, J; Saba, L1
Beck, WT; Cirtain, MC; Danks, MK; Felsted, RL; Safa, AR; Suttle, DP; Trent, JM; Wolverton, JS1
Inaba, M1
Montgomery, JA; Struck, RF1
Whittaker, JR1
Freshney, RI; Kaye, SB; Merry, S1
Geller, RL; Lilien, J1
Bonnet, F; Cany, L; Coindre, JM; de Mascarel, A; Robert, J; Vergier, B1
Behm, FG; Bowman, LC; Head, DR; Heaton, D; Hurwitz, CA; Pui, CH; Raimondi, SC; Sandoval, C1
Bloss, H; Krebs, D1
Lemmel, EM; Motycka, K; Nouza, K; Soucek, J1
Norpoth, K; Rauen, HM1
Begemann, H; Schick, P; Trepel, F1
Bergemann, H; Kaboth, W; Schick, P; Trepel, F; Wernekke, G1
Goldenberg, DM; Witte, S1
Gini, RA; Lista, GA; Schajris, MJ1
Clément, F1
Mizel, SB; Wilson, L1
GOLDENBERG, DM1
FALKSON, G; SCHULZ, EJ1
MERCIER-PAROT, L; TUCHMANN-DUPLESSIS, H1

Reviews

4 review(s) available for dactinomycin and podophyllotoxin

ArticleYear
Intravesical and systemic chemotherapy of murine bladder cancer.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Ethoglucid; FANFT; Female; Fluorouracil; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiotepa; Urinary Bladder Neoplasms

1977
Implication of prior treatment with drug combinations including inhibitors of topoisomerase II in therapy-related monocytic leukemia with a 9;11 translocation.
    Genes, chromosomes & cancer, 1990, Volume: 2, Issue:1

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Iatrogenic Disease; Leukemia, Monocytic, Acute; Mastectomy, Radical; Middle Aged; Podophyllotoxin; Radiotherapy; Tamoxifen; Topoisomerase II Inhibitors; Translocation, Genetic

1990
The chemistry of DNA modification by antitumor antibiotics.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1988, Volume: 32

    Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Dactinomycin; DNA; Duocarmycins; Indoles; Leucomycins; Mitomycins; Podophyllotoxin; Topoisomerase II Inhibitors

1988
The relationship of the metabolism of anticancer agents to their activity.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1973, Volume: 17

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azirines; Dactinomycin; Dichlorodiphenyldichloroethane; DNA, Neoplasm; Folic Acid Antagonists; Glutamine; Humans; Hydrazones; Mesylates; NADH, NADPH Oxidoreductases; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Podophyllotoxin; Procarbazine; Purines; Pyrimidines; Steroids; Triazenes

1973

Trials

1 trial(s) available for dactinomycin and podophyllotoxin

ArticleYear
Improvement of long-term survival in extensive small-cell lung cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prognosis; Random Allocation; Vincristine

1988

Other Studies

26 other study(ies) available for dactinomycin and podophyllotoxin

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Combination chemotherapy with 4'Demethylepipodophyllotoxin 9-(4,6-0-ethylidene-beta-D-glucopyranoside), VP 16-213 (NSC 141540) in L1210 leukemia.
    European journal of cancer, 1976, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Podophyllotoxin; Vincristine

1976
VP-16 in combinations for first-line treatment of malignant germ-cell tumors and gestational choriocarcinoma.
    Seminars in oncology, 1985, Volume: 12, Issue:1 Suppl 2

    Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Choriocarcinoma; Chorionic Gonadotropin; Cyclophosphamide; Cytarabine; Dactinomycin; Etoposide; Female; Humans; Male; Methotrexate; Neoplasms, Germ Cell and Embryonal; Podophyllotoxin; Pregnancy; Uterine Neoplasms; Vincristine

1985
Intrascrotal metastasis from Wilms' tumor.
    Medical and pediatric oncology, 1988, Volume: 16, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Combined Modality Therapy; Dactinomycin; Doxorubicin; Genital Neoplasms, Male; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Podophyllotoxin; Scrotum; Vincristine; Wilms Tumor

1988
Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Banding; Chromosomes, Human, Pair 13; Colchicine; Dactinomycin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Membrane Glycoproteins; Molecular Weight; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Verapamil; Vinblastine; Vinca Alkaloids

1987
[Studies on the mechanism of multidrug resistance].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Naphthacenes; Podophyllotoxin; Quinacrine; Vinca Alkaloids; Vincristine

1987
Segregation during ascidian embryogenesis of egg cytoplasmic information for tissue-specific enzyme development.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:7

    Topics: Acetylcholinesterase; Animals; Catechol Oxidase; Cell Division; Colchicine; Cytochalasin B; Cytoplasm; Dactinomycin; Female; Histocytochemistry; Monophenol Monooxygenase; Ovum; Podophyllotoxin; Puromycin; RNA; Urochordata

1973
Cross-resistance to cytotoxic drugs in human glioma cell lines in culture.
    British journal of cancer, 1984, Volume: 50, Issue:6

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Glioma; Humans; Melphalan; Podophyllotoxin; Vincristine

1984
Repair of a calcium-dependent adhesive mechanism of embryonic neural retina cells: kinetic and molecular analysis.
    Journal of cell science, 1983, Volume: 60

    Topics: Animals; Calcium; Cell Adhesion; Cell Aggregation; Chick Embryo; Colchicine; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Kinetics; Monensin; Podophyllotoxin; Retina; Time Factors; Trypsin; Tunicamycin

1983
Expression of MDR1/P glycoprotein in human sarcomas.
    British journal of cancer, 1993, Volume: 68, Issue:6

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Carrier Proteins; Dactinomycin; Drug Resistance; Gene Expression; Hemangiosarcoma; Histiocytoma, Benign Fibrous; Histocytochemistry; Humans; Immunoblotting; In Situ Hybridization; Leiomyosarcoma; Liposarcoma; Membrane Glycoproteins; Neoplasm Proteins; Podophyllotoxin; Rhabdomyosarcoma; RNA, Messenger; RNA, Neoplasm; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Tumor Cells, Cultured; Vinca Alkaloids

1993
Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:6

    Topics: Acute Disease; Adolescent; Alkylating Agents; Antineoplastic Agents; Child; Combined Modality Therapy; Dactinomycin; Doxorubicin; Female; Humans; Intercalating Agents; Leukemia, Myeloid; Male; Neoplasms, Second Primary; Podophyllotoxin; Radiotherapy; Topoisomerase II Inhibitors; Translocation, Genetic

1993
[Experimental studies on the action of various cytostatic substances on the growth of aerobic and anaerobic microorganisms].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 1966, Volume: 200, Issue:4

    Topics: Alkylating Agents; Antineoplastic Agents; Azirines; Bacteria; Bacteroides; Corynebacterium; Dactinomycin; Escherichia coli; Lactobacillus acidophilus; Methotrexate; Plants, Medicinal; Plants, Toxic; Podophyllum; Pseudomonas aeruginosa; Staphylococcus; Streptococcus; Triaziquone

1966
[The influence of age and experimentally-induced disease on the tolerance of cytostatically-active materials in mice].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:2

    Topics: Age Factors; Aminopterin; Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Tolerance; Graft vs Host Disease; Immunosuppressive Agents; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Skin Transplantation; Thioguanine; Transplantation, Homologous

1967
[Growth stimulation by sibliminal concentrations of growth-inhibiting substances].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:8

    Topics: Anilides; Animals; Bacteria; Chick Embryo; Dactinomycin; Extraembryonic Membranes; Growth Substances; Neoplasms, Experimental; Neurospora; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Pyrimidines; Thalidomide

1966
[Morphological and functional alterations of the blood cell system of guinea pigs after treatment with cytostatic agents, prednisolone and phenylbutazone. I. Alterations of different leukocyte and lymphocyte subgroups in the blood].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1968, Volume: 148, Issue:4

    Topics: Animals; Antineoplastic Agents; Blood Cells; Cyclophosphamide; Dactinomycin; Guinea Pigs; Leukocytes; Leukopenia; Lymphocytes; Mercaptopurine; Phenylbutazone; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisolone; Triethylenemelamine; Vinblastine

1968
[Morphological and functional alterations of the blood cell system of guinea pigs after treatment with cytostatic agents and prednisolone. II. Variations of cell distribution and DNA-, RNA- and protein synthesis in Haematopoietic tissues].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1968, Volume: 148, Issue:4

    Topics: Animals; Antineoplastic Agents; Autoradiography; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Dactinomycin; Guinea Pigs; Lymph Nodes; Lymphatic System; Mercaptopurine; Nucleic Acids; Nucleoproteins; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisolone; Spleen; Triethylenemelamine; Tritium; Vinblastine

1968
[Tumor-host relations in the comprehension of chemotherapeutic effects].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1968, Volume: 1, Issue:6

    Topics: Animals; Antineoplastic Agents; Cheek; Cricetinae; Dactinomycin; Humans; Hyperemia; Neoplasm Transplantation; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Transplantation, Heterologous

1968
[Autoimmune disease].
    Prensa medica argentina, 1970, Mar-20, Volume: 57, Issue:3

    Topics: Alkylating Agents; Antilymphocyte Serum; Antimetabolites; Autoimmune Diseases; Dactinomycin; Humans; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum

1970
[The chemotherapy of cancer].
    Praxis, 1967, Dec-07, Volume: 56, Issue:49

    Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Sarcoma, Ewing; Thiotepa; Vincristine

1967
Nucleoside transport in mammalian cells. Inhibition by colchicine.
    Biochemistry, 1972, Jul-04, Volume: 11, Issue:14

    Topics: Adenosine; Alkaloids; Aminoisobutyric Acids; Animals; Carbon Isotopes; Carcinoma; Cell Line; Cells, Cultured; Colchicine; Cricetinae; Cytarabine; Dactinomycin; Fetus; Fibroblasts; Guanosine; HeLa Cells; Hexoses; Humans; Lung; Mouth Neoplasms; Nucleic Acids; Nucleosides; Phosphorus Isotopes; Plants, Medicinal; Plants, Toxic; Podophyllum; Skin; Thymidine; Tritium; Uridine

1972
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
    Diseases of the chest, 1963, Volume: 51

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine

1963
SKIN CHANGES CAUSED BY CANCER CHEMOTHERAPY.
    The British journal of dermatology, 1964, Volume: 76

    Topics: Alopecia; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dermatology; Erythema; Ethoglucid; Fluorouracil; Neoplasms; Pathology; Podophyllum; Skin; Sweat Glands; Toxicology; Ulcer

1964
[REPERCUSSIONS OF NEUROLEPTIC AND ANTITUMOR AGENTS ON PRENATAL DEVELOPMENT].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1964, Volume: 20

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Antipsychotic Agents; Barbiturates; Colchicine; Dactinomycin; Folic Acid Antagonists; Glutethimide; Mice; Nitrogen Mustard Compounds; Parasympatholytics; Podophyllin; Podophyllum; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Research; Thalidomide; Toxicology; Tranquilizing Agents; Urethane

1964