dactinomycin has been researched along with orotic acid in 186 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 181 (97.31) | 18.7374 |
| 1990's | 3 (1.61) | 18.2507 |
| 2000's | 1 (0.54) | 29.6817 |
| 2010's | 1 (0.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Abeles, FB; Beall, FA; Dinterman, RE; Thompson, WL; Wannemacher, RW | 1 |
| Chatterjee, B; Dutchak, D; Hopkins, J; Roy, AK | 1 |
| Murty, CN; Sidransky, H; Verney, E | 3 |
| Seifert, J; Vácha, J | 1 |
| Brysch, B; Chorazy, M | 1 |
| Ishikawa, K; Ogata, K; Sato, T | 1 |
| Castle, T; Kreamer, W; Liu, DS; Richardson, A | 1 |
| Borney, C; Martelly, I; Moigne, AL | 1 |
| Murty, CN; Reid, M; Sarma, DS; Sidransky, H; Verney, E | 1 |
| Gross, V; Heinrich, PC; Northemann, W; Scheurlen, M; Weiss, E | 1 |
| Anderson, J; Nievel, JG; Robinson, N | 1 |
| Anderson, J; Nievel, JG; Skrbic, TR | 1 |
| Endo, Y; Natori, Y; Tominaga, H | 2 |
| Artemenko, NK; Freidlin, IS; Lyzlova, SN; Nersesova, LS; Petrova, TA | 1 |
| Gupta, SR; Prasanna, HR; Venkitasubramanian, TA; Viswanathan, L | 1 |
| Brown, CS; Heath, TD; Stern, WH | 1 |
| Bhadra, R; Datta, AG; Roy, AK; Sarkar, J | 1 |
| Handmaker, SD; Kay, JE | 1 |
| Korner, A; Oravec, M | 1 |
| Granick, S; Sassa, S | 1 |
| Ord, MG; Stocken, LA | 1 |
| Cihák, A; Garret, C; Pitot, HC | 1 |
| Carr, J; Hollingsworth, JW | 1 |
| Cihák, A; Harrap, KR; Veselý, J | 1 |
| Heuck, CC | 1 |
| Galabov, GP; Popov, PG; Vaptzarova, KI | 1 |
| Boctor, A; Grossman, A | 1 |
| Korner, A | 1 |
| Lazda, V; Starr, JL | 1 |
| Eker, P; Pihl, A | 1 |
| MacGregor, RR; Mahler, HR | 1 |
| Meerson, FZ; Rozanova, LS | 1 |
| Saito, S | 1 |
| Otaka, T; Uchyama, M | 1 |
| Aleksandrovskaia, MM; Geĭnisman, IuIa; Larina, VN; Meerson, FZ; Rozanova, LS | 1 |
| Kummer, D | 1 |
| Fanburg, BL; Matsushita, S; Raben, MS | 1 |
| Singhal, RL; Srivastava, SK; Weber, G | 4 |
| DeLuca, HF; Stohs, SJ; Zull, JE | 1 |
| Webb, TE | 1 |
| Sprecher-Goldberger, S | 1 |
| Hirschowitz, BI; Sachs, G; Tsuji, T | 1 |
| Kwan, SW; Morris, HP; Webb, TE | 1 |
| Content, J | 1 |
| Gaudernack, G; Prydz, H | 1 |
| Lawson, DE | 1 |
| Raisz, LG; Simmons, H; Trummel, CL | 1 |
| Schwartz, AL | 1 |
| Hoogenraad, NJ; Lee, DC | 1 |
| Dugan, RE; Lakshmanan, MR; Nepokroeff, CM; Ness, GC; Porter, JW | 1 |
| Harper, AE; Tews, JK | 1 |
| Farese, RV | 1 |
| Milholland, RJ; Rosen, F | 1 |
| Bakay, B; Nyhan, WL | 1 |
| Cihak, A; Pitot, HC; Wilkinson, D | 1 |
| Carlone, MF; King, SW; Magus, RD; Phillips, MW | 1 |
| Komáromy, L; Molnár, J; Tigyi, A | 2 |
| Brykina, EV; Chernovskaya, TV; Lerman, MI; Podobed, OV | 1 |
| Bezborodov, VA; Bredov, VI; Dergachev, VV; Krylov, OA; Oreshuk, FA | 1 |
| Hollatz, R; Tempel, K | 1 |
| Heuser, JE; Jablecki, CK; Kaufman, S | 1 |
| Linét, O | 1 |
| Ichii, S; Izawa, M | 2 |
| Eddy, R; Hadwiger, LA; Von Broembsen, S | 1 |
| Fanburg, BL; Matsushita, S | 1 |
| Garrett, CT; Pitot, HC; Tweedle, JW; Wilkinson, DS | 1 |
| Gravela, E | 1 |
| Abe, S; Fujisawa, T; Kawada, T; Ogata, K; Satake, M | 1 |
| Kato, K; Nawata, H | 1 |
| Witschi, H | 2 |
| Montanaro, L; Novello, F; Stirpe, F | 1 |
| Andrieu, A; Moulé, Y; Sarasin, A | 1 |
| Daniels, D | 1 |
| Christoffersen, T; Jervell, KF; Mörland, J | 1 |
| Roberts, JJ; Warwick, GP | 1 |
| Cihak, A; Pitot, HC; Wilkinson, DS | 1 |
| Murty, CN; Sidransky, H | 2 |
| Dawson, KM | 1 |
| Avakyan, ER; Coutelle, C; Georgiev, GP; Mantieva, VL; Ryskov, AP | 1 |
| Sidransky, H; Verney, E | 1 |
| Chandler, AM; Johnson, LR | 1 |
| Hiai, S; Hirai, Y; Oura, H; Tsukada, K | 1 |
| Niessing, J; Sekeris, CE | 1 |
| Leĭtin, VL; Lerman, MI; Podobed, OV | 1 |
| Baserga, R; Estensen, RD; Petersen, RO | 1 |
| Czarnowska-Misztal, E; DeLuca, HF; Zull, JE | 1 |
| Koenig, E | 1 |
| Jarrett, RJ; Keen, H; Track, N | 1 |
| Aonuma, S; Hama, T; Okumura, H; Tamaki, N | 1 |
| Cox, BM; Osman, OH | 1 |
| Dvorkin, B; Makman, MH; Nakagawa, S; White, A | 1 |
| Brossard, M; Nicole, L | 1 |
| Antoni, F; Bölöni, E; Hidvégi, EJ; Holland, J; Várterész, V | 1 |
| Veselý, J | 1 |
| Dolbeare, F; Koenig, H | 1 |
| Henderson, AR | 1 |
| Jant, BA; Johnson, JD; Kaufman, S; Sokoloff, L | 1 |
| Abe, S; Fujisawa, T; Ogata, K; Satake, M | 1 |
| Hiai, S; Nakashima, S; Oura, H; Tsukada, K | 1 |
| Reid, IM; Sarma, DS; Sidransky, H | 1 |
| Mansbridge, JN; Woodcock, DM | 1 |
| Frieden, EH; Ku, CC | 1 |
| Ito, K; Uchino, H | 1 |
| Kawada, T; Suda, S; Sugano, H; Sugano, I | 1 |
| Faloona, GR; Fried, M; Stewart, BN | 1 |
| Bongiorno, M; Sarma, DS; Sidransky, H; Verney, E | 1 |
| Frayssinet, C; Moulé, Y | 1 |
| Sanchez, S | 1 |
| Manis, J; Schachter, D; Yoshino, Y | 1 |
| Gallwitz, D; Schütz, G; Sekeris, CE | 1 |
| Goswami, A; Skipper, JK; Williams, WL | 1 |
| Fujisawa, T; Muramatsu, M | 1 |
| Hadwiger, LA; Schwochau, ME | 1 |
| Imblum, RL; O'Dell, RG; Prosky, L; Roberts, B | 1 |
| Daginawala, HF; Rappoport, DA | 1 |
| Farber, E; Stewart, GA | 1 |
| Ono, H; Terayama, H | 1 |
| Chandler, AM; Neuhaus, OW | 1 |
| Liu, AY; Neuhaus, OW | 1 |
| Spadoni, MA; Ticca, M | 1 |
| Barnabei, O; Ottolenghi, C | 1 |
| Hogan, BL; Korner, A | 1 |
| Feigelson, P; Yu, FL | 1 |
| Farber, E; Goldblatt, PJ; Sullivan, RJ | 2 |
| Fausto, N | 1 |
| Gros, F; Gupta, SL; Tawler, GP | 1 |
| Stinebring, WR; Taube, SE; Youngner, JS | 1 |
| Appel, SH | 1 |
| Greenman, DL; Kenney, FT; Wicks, WD | 1 |
| Clifford, JI; Rees, KR | 1 |
| Rowe, PB; Wyngaarden, JB | 1 |
| Tata, JR; Widnell, CC | 1 |
| Bhuyan, BK; Camiener, GW; Gray, GD | 1 |
| Busch, H; Hodnett, JL; Muramatsu, M; Steele, WJ | 1 |
| Busch, H; Steele, WJ | 1 |
| Earl, DC; Korner, A | 1 |
| Cohen, PP; Kim, KH; Nakagawa, H | 1 |
| Busch, H; Jacob, ST; Steele, WJ | 1 |
| Bresnick, E; Mossé, H; Williams, SS | 1 |
| Garofalo, M; Schwartz, HS | 1 |
| Hoagland, MB; Wilson, SH | 1 |
| Cohen, S; Hoober, JK | 1 |
| Crook, EM; Johnston, IR; Trewavas, AJ | 1 |
| Edelman, IS; Fanestil, DD; Fimognari, GM | 1 |
| Sacher, JA | 1 |
| Jackson, CD; Sells, BH | 1 |
| Niemann, I; Raisz, LG | 1 |
| Cain, DF | 1 |
| Franecki, G; Galasiński, W; Lorenc, R | 1 |
| Hikino, H; Murayama, M | 1 |
| Le Moigne, A; Martelly, I | 1 |
| Ogata, K; Usami, K | 1 |
| Castro-Osuna, G; Collado, ML; Hicks, JJ | 1 |
| Afanasova, NV; Bizer, VA; Timukhina, VN | 1 |
| Farber, E; Koo, P; Nagai, MK | 1 |
| Fransvea, E; La Piana, G; Laconi, E; Lofrumento, NE; Marzulli, D; Rajalakshmi, S; Rao, PM; Sarma, DS; Vasudevan, S | 1 |
| JERVELL, KF; OSNES, JB | 1 |
| KORNER, A; MUNRO, AJ | 1 |
| SOVIK, O; WALAAS, O | 1 |
| HIATT, HH; REVEL, M | 1 |
| LIEBERMAN, I; TSUKADA, K | 1 |
| VENIS, MA | 1 |
| GARREN, LD; HOWELL, RR; TOMKINS, GM | 1 |
| PERAINO, C; PITOT, HC | 1 |
| BARNABEI, O; SERENI, F | 1 |
| BUSCH, H; HODNETT, JL; MURAMATSU, M | 1 |
| GAROFALO, M; SCHWARTZ, HS; SODERGREN, JE; STERNBERG, SS | 1 |
| KANE, P; LIEBERMAN, I | 1 |
| BRUNS, GP; FISCHER, S; LOWY, BA | 1 |
| SOVIK, O | 1 |
| POPOVIC, DA | 1 |
| KANE, P; LIEBERMAN, I; SHORT, J | 1 |
| BALASIEWICZ, W; JASINSKA, J; JASINSKI, W; KIERYLOWICZ, A; MICHALOWSKI, A | 1 |
| Loukanina, N; Stasolla, C; Thorpe, TA; Yeung, EC | 1 |
2 review(s) available for dactinomycin and orotic acid
| Article | Year |
|---|---|
Vitamin D: new findings on its metabolism and its role in calcium nutrition.
Topics: Animals; Biological Assay; Calcium; Calcium Isotopes; Chickens; Cholecalciferol; Chromatography; Dactinomycin; Intestinal Absorption; Isomerism; Kidney; Orotic Acid; Protein Biosynthesis; Rats; RNA; Tritium; Vitamin D; Vitamin D Deficiency | 1971 |
The effect of pyrimidine analogues and tryptophan on enzyme synthesis and degradation in rat liver.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Caseins; Centrifugation, Density Gradient; Cortisone; Cytidine; Dactinomycin; Enzyme Induction; Fluorine; L-Serine Dehydratase; Leucine; Liver; Lyases; Male; Nucleoproteins; Nucleosides; Ornithine; Orotic Acid; Phenylpyruvic Acids; Protein Hydrolysates; Pyrimidines; Rats; Ribosomes; RNA; Time Factors; Transaminases; Triazines; Tritium; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase | 1970 |
184 other study(ies) available for dactinomycin and orotic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Influence of the adrenal glucocorticoids on the stimulation of synthesis of hepatic ribonucleic acid and plasma acute-phase globulins by leucocytic endogenous mediator.
Topics: alpha-Macroglobulins; Animals; Cycloheximide; Dactinomycin; Haptoglobins; Hydrocortisone; Leukocytes; Liver; Male; Orotic Acid; Proteins; Rats; RNA | 1976 |
Superinduction of alpha 2u globulin by actinomycin D: evidence for drug-mediated increase in alpha 2u mRNA.
Topics: Alpha-Globulins; Amanitins; Animals; Castration; Cycloheximide; Dactinomycin; Deoxyadenosines; Female; Liver; Orotic Acid; Protein Biosynthesis; Rats; RNA, Messenger; Transcription, Genetic | 1979 |
Turnover of messenger RNA in transplantable hepatomas and host liver of rats.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Female; Liver; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; Poly A; Polyribosomes; Rats; Rats, Inbred BUF; Ribonucleases; RNA, Messenger; RNA, Neoplasm; Transplantation, Isogeneic | 1978 |
Microsomal inducers of drug-metabolizing enzymes suppress cytidine nucleotide biosynthesis in rat liver.
Topics: Animals; Antimetabolites; Azauridine; Barbiturates; Benzopyrenes; Carbon Tetrachloride; Colchicine; Cycloheximide; Cytarabine; Cytosine Nucleotides; Dactinomycin; DDT; Hydrocortisone; Liver; Male; Methylcholanthrene; Microsomes, Liver; Orotic Acid; Puromycin; Rats; Spermidine | 1975 |
Isolation and properties of poly(A)-containing RNA from the cytoplasm of rat liver cells.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Radioisotopes; Cells, Cultured; Chromatography, Affinity; Chromatography, Gel; Cytoplasm; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Hydrogen-Ion Concentration; Liver; Methods; Nucleic Acid Denaturation; Nucleotides; Orotic Acid; Phosphates; Phosphorus Radioisotopes; Poly A-U; Polynucleotides; Rats; RNA; Temperature; Tritium; Ultrafiltration; Uridine | 1975 |
Characterization of ribonucleoprotein particles released from isolated nuclei of regenerating rat liver in two different in vitro systems.
Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Cytosol; Dactinomycin; Liver; Liver Regeneration; Molecular Weight; Nucleoproteins; Orotic Acid; Rats; Ribonucleoproteins; Ribosomes; RNA; Saccharomyces cerevisiae; Spermidine; Temperature | 1977 |
Characterization of RNA synthesis by isolated hepatocytes in suspension.
Topics: Animals; Cell Nucleus; Dactinomycin; Female; In Vitro Techniques; Kinetics; Liver; Orotic Acid; Poly A; Rats; RNA; Transcription, Genetic; Uracil; Uridine | 1979 |
[Demonstration of 2 phases in RNA synthesis during regeneration of planarian (Polycelis tenuis-nigra)].
Topics: Animals; Dactinomycin; Orotic Acid; Planarians; Regeneration; RNA; Turbellaria | 1976 |
Effect of aflatoxin B1 on hepatic polyribosomes and protein synthesis in the rat.
Topics: Aflatoxins; Amino Acids; Animals; Dactinomycin; In Vitro Techniques; Liver; Male; Orotic Acid; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Polyribosomes; Protein Biosynthesis; Rats; Ribosomes; Time Factors; Tryptophan Oxygenase | 1977 |
Comparative studies of the effects of galactosamine and actinomycin D on nuclear ribonucleoprotein particles from rat liver.
Topics: Cell Nucleus; Cytidine; Dactinomycin; Galactosamine; Liver; Nucleoproteins; Orotic Acid; Ribonucleoproteins; RNA | 1977 |
Changes in nucleotide metabolism of the liver and fate of [14C]orotate among various pyrimidines at the outset and during induction of drug-metabolizing enzymes and hepatomegaly.
Topics: Animals; Azauridine; Butylated Hydroxytoluene; Coumarins; Dactinomycin; DNA Replication; Enzyme Induction; Hepatomegaly; Liver; Orotic Acid; Phenobarbital; Protein Biosynthesis; Rats; Ribonucleotides; Transcription, Genetic; Uracil | 1976 |
Studies on the relationship between induction of drug-metabolizing enzymes, liver enlargement and ascorbic acid excretion in rodents.
Topics: Animals; Ascorbic Acid; Azauridine; Butylated Hydroxytoluene; Coumarins; Dactinomycin; Enzyme Induction; Female; Glucuronates; Hepatomegaly; Liver; Orotic Acid; Phenobarbital; Proadifen; Rats; Transcription, Genetic; Uracil; Uracil Nucleotides | 1976 |
Effect of tryptophan on polyriboadenylic acid and polyadenylic acid-messenger ribonucleic acid in rat liver.
Topics: Adenosine; Animals; Cycloheximide; Dactinomycin; Deoxyadenosines; Fasting; Female; Leucine; Liver; Orotic Acid; Poly A; Polyribosomes; Proteins; Rats; RNA; RNA, Messenger; Tryptophan | 1976 |
The state of messenger ribonucleic acid and ribosomes in the cytoplasm of ethionine-treated rat liver.
Topics: Animals; Cytoplasm; Dactinomycin; Ethionine; Female; Liver; Nucleoproteins; Orotic Acid; Polyribosomes; Rats; Ribosomes; RNA, Messenger; RNA, Transfer | 1975 |
[Changes in the functional activity of macrophages, their morphology and metabolism under the influence of several biologically active substances].
Topics: Ascorbic Acid; Carbon Radioisotopes; Cathepsins; Chloramphenicol; Chloroquine; Creatine Kinase; Culture Techniques; Cycloheximide; Dactinomycin; Lipopolysaccharides; Lysine; Macrophages; Orotic Acid; Peritoneum; Phagocytosis; Protein Biosynthesis; Puromycin; Rifampin; RNA; Tetracycline; Uridine | 1975 |
A comparative study of the effects of aflatoxin B1, alpha-amanitin and actinomycin-D on RNA synthesis by rat liver.
Topics: Aflatoxins; Amanitins; Animals; Dactinomycin; Liver; Male; Orotic Acid; Rats; RNA; Subcellular Fractions | 1975 |
Ocular cicatricial disease. Drug effects in vitro on cell proliferation, contraction, and viability.
Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Cicatrix; Dactinomycin; Daunorubicin; Orotic Acid; Rabbits; Retinal Diseases; Skin; Tunicamycin | 1990 |
Effect of amines on fibrinogen synthesis.
Topics: Animals; Dactinomycin; Epinephrine; Fibrinogen; Isoproterenol; Leucine; Liver; Orotic Acid; Phosphates; Rats; Rats, Inbred Strains; RNA; Serotonin; Time Factors | 1985 |
Uridine incorporation and RNA synthesis during stimulation of lymphocytes by PHA.
Topics: Aspartic Acid; Cycloheximide; Dactinomycin; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Orotic Acid; Phosphotransferases; Prostaglandins; RNA; Stimulation, Chemical; Time Factors; Tritium; Uridine | 1970 |
Stimulation of synthesis of DNA-like and ribosomal RNA by growth hormone.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA; Growth Hormone; Guanidines; Hypophysectomy; Liver; Male; Methionine; Molecular Weight; Nucleosides; Orotic Acid; Rats; Ribosomes; RNA; RNA, Ribosomal; Tritium | 1971 |
Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Acyltransferases; Allyl Compounds; Animals; Chick Embryo; Culture Techniques; Dactinomycin; Depression, Chemical; Enzyme Induction; Etiocholanolone; Half-Life; Heme; Hexachlorocyclohexane; Leucine; Liver; Orotic Acid; Pyridones; RNA, Messenger; Time Factors | 1970 |
Uptake of amino acids and nucleic acid precursors by regenerating rat liver.
Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine | 1972 |
Labeling of cytoplasmic liver RNA by (6- 14 C)orotic and 5-fluoro(2- 14 C)orotic acids. Effect of several inhibitors.
Topics: Animals; Aza Compounds; Azacitidine; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cytoplasm; Dactinomycin; Fluorine; Liver; Male; Orotic Acid; Polyribosomes; Rats; RNA; RNA, Messenger; RNA, Ribosomal; Time Factors | 1973 |
3H-uridine incorporation as a T lymphocyte indicator in the rat.
Topics: Adenine; Adenosine; Animals; Ascitic Fluid; Autoradiography; Cycloheximide; Cytidine; Dactinomycin; Female; Lymphocyte Depletion; Lymphopenia; Male; Orotic Acid; Phosphorus Isotopes; Polyethylenes; Puromycin; Rats; Rats, Inbred Strains; T-Lymphocytes; Thoracic Duct; Tritium; Uridine | 1973 |
Enhancement of rat liver uridine kinase activity by various metabolic inhibitors.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Azauridine; Carbon Radioisotopes; Cell-Free System; Cycloheximide; Dactinomycin; Daunorubicin; Diet; Doxorubicin; In Vitro Techniques; Liver; Male; Orotic Acid; Phosphotransferases; Puromycin; Pyrimidines; Rats; Stimulation, Chemical; Thioacetamide; Thymus Gland; Uridine | 1974 |
RNA synthesis in islets of Langerhans from rats during glucose stimulation in vivo and in vitro.
Topics: Animals; Biological Transport; Dactinomycin; Glucose; In Vitro Techniques; Islets of Langerhans; Male; Molecular Weight; Orotic Acid; Rats; RNA; Stimulation, Chemical; Uridine | 1973 |
Tyrosine-alpha-ketoglutarate aminotransferase activity in rat liver after spinal cord section.
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Carbon Isotopes; Corticosterone; Cycloheximide; Dactinomycin; Enzyme Induction; Glucose; Hydrocortisone; Hypophysectomy; Kinetics; Liver; Male; Orotic Acid; Peritoneum; Pituitary Gland; Rats; Spinal Cord; Tritium; Tyrosine Transaminase | 1973 |
Differential sensitivity of rat liver and rat hepatoma cells to alpha-amanitin.
Topics: Adrenalectomy; Animals; Basidiomycota; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Dactinomycin; DNA-Directed RNA Polymerases; Enzyme Induction; Hydrocortisone; Liver; Liver Neoplasms; Mycotoxins; Nucleotides; Oligopeptides; Orotic Acid; Peptides, Cyclic; Rats; Tritium; Tyrosine Transaminase; Uracil; Uridine | 1973 |
Regulation of the rate of synthesis of messenger ribonucleic acid by growth hormone.
Topics: Animals; Dactinomycin; Growth Hormone; Hypophysectomy; In Vitro Techniques; Nucleotidyltransferases; Orotic Acid; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger | 1964 |
The stability of messenger ribonucleic acid in antibody synthesis.
Topics: Animals; Antibody Formation; Dactinomycin; DNA; gamma-Globulins; Hemagglutination Tests; In Vitro Techniques; Nucleosides; Orotic Acid; Rabbits; Ribosomes; RNA; RNA, Messenger; Spleen | 1965 |
Biochemical effects of prednisolone on human liver cells in tissue culture.
Topics: Alanine; Carbon Isotopes; Cell Division; Dactinomycin; DNA; Fructose-Bisphosphatase; Glucokinase; Glucose; Glucose-6-Phosphatase; Glycogen; Hexokinase; Humans; Liver; Methionine; Orotic Acid; Prednisolone; Proteins; Puromycin; Pyruvates; RNA; Thymidine | 1966 |
RNA synthesis in intact rat liver nuclei.
Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Dactinomycin; Deoxyribonucleases; Fluorides; Histones; In Vitro Techniques; Liver; Magnesium; Male; Manganese; Nucleotides; Nucleotidyltransferases; Orotic Acid; Quaternary Ammonium Compounds; Rats; Ribonucleases; RNA; Thymus Gland; Triamcinolone | 1967 |
[The effect of actinomycin 2703 and a complex stimulating nucleic acid synthesis on the development of fatigue and training state].
Topics: Animals; Behavior, Animal; Dactinomycin; Fatigue; Folic Acid; Mice; Nucleic Acids; Orotic Acid; Vitamin B 12 | 1966 |
[Growth hormone].
Topics: Alkaline Phosphatase; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Animals; Carbon Isotopes; Dactinomycin; Diaphragm; Dwarfism, Pituitary; Growth Hormone; Humans; Hydroxyproline; In Vitro Techniques; Leucine; Leucyl Aminopeptidase; Liver; Male; Nitrogen; Orotic Acid; Protein Biosynthesis; Puromycin; Pyruvates; Radioisotopes; Rats; RNA | 1967 |
Stimulatory effect of ecdysterone on RNA synthesis in mouse liver.
Topics: Amino Acids; Animals; Carbon Isotopes; Cholestanes; Cytoplasm; Dactinomycin; Liver; Male; Mice; Orotic Acid; RNA; RNA, Messenger; Sucrose; Ultracentrifugation | 1969 |
[Comparative evaluation of the effect of actinomycin 2703 and of orotic acid on the dimensions of spinal motor neurons subjected to motor load].
Topics: Animals; Cell Nucleus; Cytoplasm; Dactinomycin; Fatigue; Male; Mice; Motor Neurons; Orotic Acid; Physical Exertion; RNA; Spinal Nerves | 1967 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Nucleic acid metabolism in cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Dactinomycin; DNA; Male; Myocardium; Nucleic Acid Precursors; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Orotic Acid; Pyrimidine Nucleotides; Pyrophosphatases; Rats; Ribonucleotides; RNA; RNA, Ribosomal; RNA, Transfer | 1973 |
Effect of nutritional state on hormonal regulation of liver enzymes.
Topics: Animals; Cortisone; Dactinomycin; Ethionine; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; In Vitro Techniques; Insulin; Liver; Orotic Acid; Rats; RNA; Starvation; Subcellular Fractions; Triamcinolone | 1965 |
Vitamin D stimulation of [3H]orotic acid incorporation into ribonucleic acid of rat intestinal mucosa.
Topics: Animals; Calcium; Cholecalciferol; Chromatography, Paper; Dactinomycin; Drug Antagonism; Injections, Intraperitoneal; Intestinal Mucosa; Kidney; Liver; Male; Orotic Acid; Rats; RNA; Spectrophotometry; Tritium; Vitamin D Deficiency | 1967 |
Polyribosome breakdown in rat liver following administration of 8-azaguanine.
Topics: Animals; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellular; Dactinomycin; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Orotic Acid; Rats; Ribosomes; RNA, Messenger | 1967 |
The existence of two different metabolic patterns for the synthesis of RNA viruses.
Topics: Adenine; Animals; Antimetabolites; Chick Embryo; Culture Media; Dactinomycin; Enterovirus; Fibroblasts; Formates; Histones; Influenza A virus; Methotrexate; Nucleosides; Orotic Acid; Phenylalanine; Puromycin; Radiation Effects; RNA Viruses; RNA, Viral; Thymidine; Ultraviolet Rays; Uridine | 1966 |
Murine hepatitis virus: effect on liver RNA.
Topics: Alanine Transaminase; Animals; Carbon Isotopes; Dactinomycin; Hepatitis A; Hepatitis, Animal; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Liver; Mice; Murine hepatitis virus; Orotic Acid; RNA | 1968 |
Diversity and nature of ribosomal pools in hepatoma 7800 and host liver.
Topics: Animals; Azaguanine; Carbon Isotopes; Carbon Tetrachloride; Carcinoma, Hepatocellular; Dactinomycin; Ferritins; Liver; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Puromycin; Rats; Ribosomes | 1968 |
Virus growth inhibition by ethidium chloride and other dyes.
Topics: Acridines; Animals; Carbon Isotopes; Chick Embryo; Coloring Agents; Culture Techniques; Dactinomycin; Encephalitis Viruses; Encephalomyocarditis virus; Fibroblasts; Herpesviridae; Influenza A virus; Light; Newcastle disease virus; Orotic Acid; Poliovirus; Uridine; Vaccinia virus; Virus Replication | 1969 |
Studies on the biosynthesis of factor VII (proconvertin). The mode of action of warfarin.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Blood Coagulation Tests; Carbon Isotopes; Cyclic AMP; Cycloheximide; Dactinomycin; Diphosphates; Edetic Acid; Factor VII; In Vitro Techniques; Leucine; Ligases; Liver; Magnesium; Male; Membranes; Microsomes, Liver; Orotic Acid; Potassium; Puromycin; Pyruvate Kinase; Pyruvates; Rats; Sodium; Time Factors; Tritium; Ultrasonics; Warfarin | 1971 |
Induction of bone resorption in tissue culture. Prolonged response after brief exposure to parathyroid hormone or 25-hydroxycholecalciferol.
Topics: Alkaloids; Animals; Bone Resorption; Calcitonin; Calcium; Calcium Isotopes; Cholecalciferol; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Fetus; Magnesium; Orotic Acid; Parathyroid Hormone; Phosphates; Plicamycin; Prostaglandins; RNA; Theophylline; Time Factors; Tritium; Uridine; Vitamin A | 1972 |
Influence of glucagon, 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate and triamcinolone on the arginine synthetase system in perinatal rat liver.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Citrulline; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Gestational Age; Glucagon; Hydrocortisone; Leucine; Ligases; Liver; Lyases; Microscopy, Electron; Organ Culture Techniques; Orotic Acid; Pregnancy; Rats; Triamcinolone | 1972 |
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; DNA, Neoplasm; Glutamine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleotides; Rats; Ribonucleotides; RNA, Neoplasm; Uridine | 1974 |
Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone.
Topics: Alcohol Oxidoreductases; Animals; Bucladesine; Carbon Radioisotopes; Chromatography, Paper; Circadian Rhythm; Dactinomycin; Diabetes Mellitus; Glucagon; Glutarates; Hydrocortisone; Insulin; Male; Mevalonic Acid; Microsomes, Liver; Orotic Acid; Rats; Streptozocin; Theophylline; Time Factors | 1974 |
Effect of actinomycin D, cycloheximide and puromycin on hepatic adenosine 3',5'-monophosphate in rats treated with glucagon.
Topics: Animals; Carbon Radioisotopes; Cyclic AMP; Cycloheximide; Dactinomycin; Glucagon; Half-Life; In Vitro Techniques; Leucine; Liver; Male; Orotic Acid; Puromycin; RNA; Time Factors; Tritium | 1974 |
Effects of actinomycin D on ACTH-induced corticosteroidogenesis.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cattle; Dactinomycin; Hexosephosphates; In Vitro Techniques; NADP; Orotic Acid; Rats; RNA | 1966 |
Effects of casein hydrolysate on the induction and regulation of tyrosine-alpha-ketoglutarate transaminase in rat liver.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Caseins; Cycloheximide; Dactinomycin; Dietary Proteins; Drug Synergism; Enzyme Induction; Hydro-Lyases; Hydrocortisone; Liver; Orotic Acid; Peroxidases; Protein Biosynthesis; Rats; RNA; Serine; Time Factors; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase | 1968 |
Effects of thalidomide and chlorcyclizine on the biosynthesis of nucleic acids and proteins in fetal and maternal tissues of the rat.
Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography, Thin Layer; Dactinomycin; DNA; Female; Fetus; Glycine; Histamine H1 Antagonists; Kidney; Leucine; Liver; Nucleic Acids; Orotic Acid; Piperazines; Pregnancy; Pregnancy, Animal; Protein Biosynthesis; Rats; RNA; Spleen; Thalidomide; Thymidine; Tritium | 1970 |
Enhancement by carbon tetrachloride treatment of hepatic tyrosine amino-transferase induction in the presence of net polyribosome breakdown in the rat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Carbon Tetrachloride; Centrifugation, Density Gradient; Dactinomycin; Enzyme Induction; Fluorouracil; Hydrocortisone; Hypophysectomy; Kinetics; Liver; Male; Orotic Acid; Pituitary Gland; Rats; Ribosomes; RNA; Tryptophan Oxygenase; Tyrosine Transaminase | 1972 |
Electron microscopic study of the nuclear ribonucleoprotein components containing dRNA.
Topics: Animals; Carbon Radioisotopes; Cell Nucleus; Dactinomycin; Fasting; Female; Liver; Male; Microscopy, Electron; Nucleoproteins; Orotic Acid; Rats; Rats, Inbred Strains; RNA; Time Factors | 1974 |
Lack of correlation between the lifetimes of mRNA and the initial lengths of their poly A segments.
Topics: Adenine; Adenosine Monophosphate; Animals; Base Sequence; Carbon Radioisotopes; Dactinomycin; Drug Stability; Electrophoresis, Polyacrylamide Gel; Isotope Labeling; Kinetics; Liver; Mice; Molecular Weight; Orotic Acid; Pancreas; Polyribosomes; Ribonucleases; Ribonucleotides; RNA, Messenger; Time Factors | 1974 |
[Relation of an inhibitor of DNA-dependent RNA synthesis and stimulators of nucleic acid and protein metabolism to the electrical activity of skin mechanoreceptors].
Topics: Animals; Dactinomycin; Depression, Chemical; DNA; Folic Acid; Male; Mechanoreceptors; Neural Conduction; Orotic Acid; Proteins; Rats; RNA; Skin; Stimulation, Chemical; Vitamin B 12 | 1974 |
[Induction effects in the mouse under the influence of polyanions].
Topics: Aniline Compounds; Animals; Carbon Radioisotopes; Dactinomycin; DNA; Enzyme Induction; Female; Folic Acid; In Vitro Techniques; Kidney; Mice; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Orotic Acid; Phenobarbital; Phenylalanine; Polysaccharides; Protein Biosynthesis; RNA; Sulfuric Acids | 1974 |
Autoradiographic localization of new RNA synthesis in hypertrophying skeletal muscle.
Topics: Animals; Autoradiography; Cell Fractionation; Connective Tissue; Dactinomycin; Fibroblasts; Hypertrophy; Macrophages; Microscopy, Electron; Microscopy, Phase-Contrast; Muscles; Orotic Acid; Rats; RNA; Time Factors; Tissue Extracts; Tritium; Uridine | 1973 |
The heterogeneity of informofer. II. Differential effect of actinomycin-D on nuclear particles containing different types of dRNA.
Topics: Animals; Carbon Radioisotopes; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Histocytochemistry; Liver; Male; Microscopy, Electron; Nucleoproteins; Orotic Acid; Rats; RNA; Spectrophotometry, Ultraviolet; Time Factors | 1972 |
Contribution to the existence of regulatory mechanisms at the adrenal level.
Topics: Adrenal Glands; Animals; Butanones; Carbon Isotopes; Corticosterone; Cycloheximide; Dactinomycin; Hydrocortisone; In Vitro Techniques; Leucine; Male; Orotic Acid; Rats; RNA; Time Factors; Tissue Extracts | 1972 |
Studies on ribonucleic acid turnover in rat organs: effects of cortisol, actinomycin D, and cycloheximide.
Topics: Adrenalectomy; Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Fasting; Hydrocortisone; Kidney; Liver; Male; Orotic Acid; Rats; RNA; Spleen; Stimulation, Chemical; Tritium | 1972 |
Increased template activity in chromatin from cadmium chloride treated pea tissues.
Topics: Ammonia-Lyases; Cadmium; Carbon Isotopes; Chlorides; Chromatin; Cinnamates; Dactinomycin; DNA-Directed RNA Polymerases; Kinetics; Orotic Acid; Phenylalanine; Plant Cells; RNA; Templates, Genetic; Tritium; Water | 1973 |
The effect of calcium on labeling of nucleic acids with radioactive precursors in heart tissue slices.
Topics: Animals; Calcium; Chromatography, Thin Layer; Culture Media; Culture Techniques; Cytidine; Dactinomycin; DNA; Male; Myocardium; Orotic Acid; Perfusion; Pyrimidine Nucleotides; Rats; RNA; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Uracil; Uracil Nucleotides; Uridine | 1973 |
Effect of 5-fluoroorotic acid administration of the 32 P base composition, DNA-RNA hybridization properties, and labeling of polyadenylate-rich RNA in the cytoplasm of rat liver cells.
Topics: Adenosine Monophosphate; Animals; Base Sequence; Centrifugation, Density Gradient; Chromatography, Gel; Cytosol; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Liver; Male; Microsomes, Liver; Nucleic Acid Hybridization; Orotic Acid; Phosphorus Isotopes; Polyribosomes; Rats; RNA; RNA, Ribosomal; Tritium | 1973 |
Evidence for a reduced active life-span of messenger RNA in liver of rats poisoned with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Dactinomycin; Liver; Male; Orotic Acid; Polyribosomes; Rats; RNA, Messenger; RNA, Ribosomal; Tritium | 1973 |
RNA turnover in bound and free ribosomes from rat liver. Effects of cortisol, actinomycin D, and cycloheximide.
Topics: Animals; Cycloheximide; Dactinomycin; Half-Life; Hydrocortisone; Liver; Orotic Acid; Rats; RNA, Ribosomal; Tritium | 1973 |
Studies on the processing of 45-S RNA in rat liver nucleolus with specific reference to 29.5-S RNA.
Topics: Animals; Carbon Radioisotopes; Cell Nucleolus; Cytoplasm; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Isotope Labeling; Kinetics; Liver; Liver Regeneration; Methods; Molecular Weight; Nucleic Acid Conformation; Orotic Acid; Phenols; Rats; RNA; Sodium Dodecyl Sulfate; Temperature; Thioacetamide; Time Factors; Tritium | 1973 |
Ribonucleic acid synthesis in porphyric rat liver induced by 3,5-dicarbethoxy-1,4-dihydrocollidine.
Topics: 5-Aminolevulinate Synthetase; Animals; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Dicarboxylic Acids; DNA; Enzyme Induction; Kinetics; Liver; Orotic Acid; Phosphorus Radioisotopes; Polyribosomes; Porphyrias; Proteins; Pyridines; Rats; RNA; Time Factors | 1973 |
Qualitative and quantitative aspects of the biosynthesis of ribonucleic acid and of protein in the liver and the lung of the Syrian golden hamster.
Topics: Animals; Aspartate Carbamoyltransferase; Carbon Radioisotopes; Carboxy-Lyases; Cricetinae; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Leucine; Liver; Lung; Orotic Acid; Pentosyltransferases; Phosphotransferases; Protein Biosynthesis; Pyrimidine Nucleotides; Pyrimidines; Ribonucleotides; RNA; Uridine | 1973 |
Inhibition of ribonucleic acid and of protein synthesis in the organs of rats and mice poisoned with alpha-amanitin.
Topics: Animals; Basidiomycota; Carbon Radioisotopes; Cell Nucleus; Dactinomycin; DNA-Directed RNA Polymerases; Glutathione; Kidney; Liver; Male; Mice; Mycotoxins; Oligopeptides; Organ Specificity; Orotic Acid; Peptides, Cyclic; Phenylalanine; Protein Biosynthesis; Rats; Ribosomes; RNA; Species Specificity; Time Factors | 1973 |
Studies on mRNA of the livers of rats force-fed a threonine-devoid or complete diet.
Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Dactinomycin; Deficiency Diseases; Deoxycholic Acid; Diet; Disease Models, Animal; Female; Kwashiorkor; Leucine; Liver; Orotic Acid; Polyribosomes; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Ribosomal; Subcellular Fractions; Threonine | 1974 |
[40 S ribonucleoproteins from rat liver nuclei. II. Properties of the RNA of these particles].
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Nucleus; Cell-Free System; Dactinomycin; Escherichia coli; Leucine; Liver; Male; Nucleoproteins; Nucleotides; Orotic Acid; Phosphorus Isotopes; Protein Biosynthesis; Puromycin; Rats; Ribosomes; RNA; Spectrophotometry; Time Factors; Ultraviolet Rays | 1969 |
Effects of actinomycin D on memory and brain RNA synthesis in an appetitive learning task.
Topics: Animals; Appetitive Behavior; Brain; Carbon Isotopes; Cerebral Cortex; Dactinomycin; Depression, Chemical; Exploratory Behavior; Hippocampus; Male; Memory; Motor Activity; Orotic Acid; Rats; RNA; Sodium Chloride; Thalamus | 1971 |
Studies on the 3-methylcholanthrene induction and carbohydrate repression of rat liver dimethylaminoazobenzene reductase.
Topics: Animals; Dactinomycin; Enzyme Repression; Ethionine; In Vitro Techniques; Liver; Methylcholanthrene; Orotic Acid; Oxidoreductases; p-Dimethylaminoazobenzene; Rats; RNA | 1965 |
Covalent binding of 4-dimethylaminophenylazo-3H-benzene (butter yellow) metabolites with liver ribosomal RNA: the dissociation of the binding mechanism from the orotic acid incorporating system.
Topics: Animals; Dactinomycin; Liver; Male; Orotic Acid; p-Dimethylaminoazobenzene; Rats; Ribosomes; RNA | 1966 |
Inhibition of ribosomal ribonucleic acid maturation in rat liver by 5-fluoroorotic acid resulting in the selective labeling of cytoplasmic messenger ribonucleic acid.
Topics: Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Edetic Acid; Electrophoresis; Fluorine; Liver; Male; Molecular Weight; Nucleoproteins; Orotic Acid; Rats; Ribosomes; RNA, Messenger; RNA, Ribosomal; Time Factors | 1971 |
The effect of tryptophan on messenger RNA of the liver of fasted mice.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Fasting; Female; Isotope Labeling; Liver; Mice; Orotic Acid; Ribosomes; RNA; RNA, Messenger; RNA, Ribosomal; Subcellular Fractions; Time Factors; Tryptophan; Ultracentrifugation | 1972 |
A comparative study of in vivo RNA and protein synthesis in rat liver and lung.
Topics: Amines; Animals; Carbon Isotopes; Carbon Tetrachloride; Cycloheximide; Dactinomycin; Ethionine; Female; Leucine; Liver; Lung; Male; Nickel; Nitroso Compounds; Orotic Acid; Protein Biosynthesis; Rats; RNA; Urethane; Uridine | 1972 |
Time course of the effect of AAF on mouse liver nucleic acid synthesis and its modification by inhibitors.
Topics: Acetates; Animals; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA; Fluorenes; Hydroxyurea; Leucine; Liver; Male; Mice; Orotic Acid; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; RNA, Ribosomal; RNA, Transfer; Thymidine; Time Factors; Tritium; Uridine; Urinary Bladder | 1972 |
On the structure of transcriptional unit in mammalian cells.
Topics: Animals; Base Sequence; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; DNA; DNA Replication; Liver; Mice; Molecular Weight; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Orotic Acid; Phosphates; Rats; RNA; RNA, Messenger; RNA, Ribosomal; Tritium | 1972 |
Effect of diet and tryptophan on hepatic polyribosomal disaggregation due to actinomycin D.
Topics: Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cortisone; Dactinomycin; Diet; Enzyme Induction; Female; Food Deprivation; Injections, Intraperitoneal; Leucine; Liver; Orotic Acid; Polyribosomes; Protein Biosynthesis; Rats; RNA; Tritium; Tryptophan; Tryptophan Oxygenase | 1972 |
Pentagastrin-stimulated incorporation of 14 C-orotic acid into RNA of gastric and duodenal mucosa.
Topics: Animals; Carbon Isotopes; Dactinomycin; Duodenum; Gastric Mucosa; Intestinal Mucosa; Liver; Orotic Acid; Pentagastrin; Rats; RNA; Stimulation, Chemical | 1972 |
Studies on the turnover of mRNA in free and membrane-bound polyribosomes in rat liver.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Female; Half-Life; Isotope Labeling; Liver; Membranes; Orotic Acid; Polyribosomes; Rats; Ribonucleases; RNA, Messenger; RNA, Ribosomal; Time Factors | 1972 |
Stimulating effect of Panax ginseng extract on RNA polymerase activity in rat liver nuclei.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Cytosine Nucleotides; Dactinomycin; Leucine; Liver; Male; Orotic Acid; Panax; Plant Extracts; Plants, Medicinal; Puromycin; Rats; RNA Nucleotidyltransferases; Stimulation, Chemical; Tritium | 1971 |
Further studies on nuclear ribonucleoprotein particles containing DNA-like RNA from rat liver.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Detergents; Electrophoresis; Kinetics; Liver; Male; Mycotoxins; Nucleoproteins; Orotic Acid; Rats; Ribonucleases; RNA; Sulfuric Acids; Tritium | 1971 |
[Cytoplasmic precursors of polyribosomes].
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Male; Orotic Acid; Rats; Ribosomes; RNA, Messenger | 1971 |
Inhibition of DNA synthesis in Ehrlich ascites cells by actinomycin D. II. The presynthetic block in the cell cycle.
Topics: Animals; Autoradiography; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Division; Dactinomycin; DNA, Neoplasm; In Vitro Techniques; Mice; Orotic Acid; RNA; RNA, Neoplasm; Thymidine; Thymidine Kinase; Tritium; Ultracentrifugation; Uridine | 1965 |
On the relationship between vitamin D action and actinomycin-sensitive processes.
Topics: Animals; Biological Transport; Calcium; Dactinomycin; Intestinal Absorption; Intestinal Mucosa; Orotic Acid; Puromycin; Rats; Vitamin D | 1966 |
Synthetic mechanisms in the axon. IV. In vitro incorporation of [3H]precursors into axonal protein and RNA.
Topics: Adenine; Animals; Axons; Chloramphenicol; Dactinomycin; In Vitro Techniques; Leucine; Microscopy, Phase-Contrast; Nerve Tissue Proteins; Orotic Acid; Photomicrography; Rabbits; Ribonucleases; RNA; Spinal Nerves; Tritium | 1967 |
Glucose and RNA synthesis in mammalian islets of Langerhans.
Topics: Animals; Carbon Isotopes; Dactinomycin; Glucose; In Vitro Techniques; Islets of Langerhans; Orotic Acid; Rats; Ribonucleases; RNA | 1967 |
Orotate as a beta-alanine donor for anserine and carnosine biosynthesis, and effects of actinomycin D and azauracil on their pathway.
Topics: Alanine; Amino Acids; Animals; Autoanalysis; Autoradiography; Body Weight; Carbon Isotopes; Chromatography, Paper; Dactinomycin; Depression, Chemical; Dipeptides; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Muscle Proteins; Muscles; Orotic Acid; Rats; RNA; Skeleton; Stimulation, Chemical; Temperature; Time Factors; Triazines; Uracil | 1969 |
Inhibition of the development of tolerance to morphine in rats by drugs which inhibit ribonucleic acid or protein synthesis.
Topics: Animals; Brain; Carbon Isotopes; Cycloheximide; Dactinomycin; Depression, Chemical; Drug Tolerance; Female; Fluorouracil; Lysine; Male; Mercaptopurine; Morphine; Orotic Acid; Protein Biosynthesis; Puromycin; Rats; RNA | 1970 |
Inhibitory effects of cortisol and antibiotics on substrate entry and ribonucleic acid synthesis in rat thymocytes in vitro.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Glycine; Hydrocortisone; Male; Orotic Acid; Progesterone; Protein Biosynthesis; Puromycin; Rats; RNA; RNA Nucleotidyltransferases; Thymus Gland; Tritium; Uridine | 1970 |
Effects of actinomycin D on the synthesis of polydisperse, rapidly labelled, nucleoplasmic RNA in rat liver.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Depression, Chemical; Injections, Intraperitoneal; Liver; Male; Orotic Acid; Rats; RNA; Tritium | 1970 |
The effect of whole-body x-irradiation of guinea pigs on liver ribonucleic acid synthesis.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Genetic Code; Guinea Pigs; Liver; Male; Microsomes, Liver; Orotic Acid; Phenylalanine; Radiation Effects; RNA; RNA Nucleotidyltransferases | 1970 |
Enhanced DNA-dependent RNA polymerase and RNA synthesis in rat liver nuclei after administration of L-tryptophan.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Cell Nucleus; Dactinomycin; DNA; Enzyme Activation; Liver; Magnesium; Nucleosides; Orotic Acid; Quaternary Ammonium Compounds; Rats; RNA; RNA Nucleotidyltransferases; Stimulation, Chemical; Sulfates; Tritium; Tryptophan | 1970 |
Fractionation of rat liver chromatins: effects of cations, hepatectomy and actinomycin D.
Topics: Animals; Calcium; Calcium Isotopes; Centrifugation, Density Gradient; Chromosomes; Dactinomycin; DNA; Hepatectomy; Liver; Liver Regeneration; Magnesium; Orotic Acid; Phospholipids; Potassium; Rats; RNA; Sodium | 1970 |
The effect of feeding with a tryptophan-free amino acid mixture on rat liver magnesium ion-activated deoxyribonucleic acid-dependent ribonucleic acid polymerase.
Topics: Amino Acids; Animals; Cell Nucleus; Cycloheximide; Dactinomycin; Diet; DNA; Enzyme Activation; Guanine Nucleotides; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Male; Nucleotides; Orotic Acid; Protein Biosynthesis; Puromycin; Rats; RNA; RNA Nucleotidyltransferases; Starvation; Time Factors; Tritium; Tryptophan | 1970 |
Effects of ionic strength on the RNA polymerase activities of isolated nuclei and nucleoli of rat liver.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Dactinomycin; Depression, Chemical; Liver; Magnesium; Male; Manganese; Orotic Acid; Osmolar Concentration; Quaternary Ammonium Compounds; Rats; RNA; RNA Nucleotidyltransferases; Stimulation, Chemical; Sulfates | 1971 |
Rat liver nucleolar 29.5S RNA as the precursor of nucleolar 28S RNA.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Dactinomycin; Densitometry; Deoxyribonucleases; Electrophoresis; Injections, Intraperitoneal; Liver; Orotic Acid; Rats; RNA | 1971 |
Stimulating effect of the roots of Panax ginseng C. A. Meyer on the incorporation of labeled precursors into rat liver RNA.
Topics: Animals; Carbon Isotopes; Dactinomycin; Injections, Intraperitoneal; Liver; Male; Medicine, East Asian Traditional; Orotic Acid; Panax; Phosphates; Phosphorus Isotopes; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Ribosomes; RNA; Tritium | 1971 |
Actinomycin D and hepatic polyribosomal disaggregation. Evidence for different half-lives of mRNA of free and membrane-boudn polyribosomes.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Depression, Chemical; Female; Half-Life; In Vitro Techniques; Leucine; Liver; Mice; Microscopy, Electron; Orotic Acid; Protein Biosynthesis; Ribosomes; RNA, Messenger | 1971 |
Effect of actinomycin D on turnover rate of messenger ribonucleic acid in rat liver.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Female; Half-Life; Kinetics; Liver; Orotic Acid; Rats; Ribonucleases; Ribosomes; RNA, Messenger; Time Factors | 1971 |
Rapidly labelled ribonucleoprotein particles in rat liver cytoplasm and their relevance to the transport of messenger RNA.
Topics: Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Cesium; Chlorides; Cycloheximide; Cytoplasm; Dactinomycin; Female; Liver; Magnesium; Male; Microsomes, Liver; Nucleoproteins; Orotic Acid; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; RNA; RNA, Messenger; RNA, Ribosomal; Sucrose; Surface-Active Agents; Tritium | 1971 |
Acute effects of testosterone propionate upon RNA synthesis in mouse kidney.
Topics: Animals; Carbon Isotopes; Chromatography; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Female; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Mice; Orotic Acid; RNA; Testosterone; Time Factors; Uracil Nucleotides | 1971 |
Control of pyrimidine biosynthesis in human lymphocytes. Induction of glutamine-utilizing carbamyl phosphate synthetase and operation of orotic acid pathway during blastogenesis.
Topics: Adult; Anhydrides; Carbamates; Carbon Dioxide; Carbon Isotopes; Cell Differentiation; Cell Line; Chemical Precipitation; Chromatography, Ion Exchange; Chromatography, Paper; Citrulline; Culture Techniques; Dactinomycin; Electrophoresis; Enzyme Induction; Glutamates; Glutamine; Humans; Hydrolysis; Lectins; Lymphocytes; Orotic Acid; Paper; Phosphoric Acids; Phosphotransferases; Puromycin; Pyrimidines; Quaternary Ammonium Compounds; Sulfates; Uracil; Uracil Nucleotides | 1971 |
Characterization of rapidly labeled 40-S ribonucleoprotein particles in rat liver cytoplasm.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; In Vitro Techniques; Liver; Nucleoproteins; Nucleotides; Orotic Acid; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; RNA, Messenger; RNA, Ribosomal | 1971 |
The effects of actinomycin D on the siosynthesis of plasma lipoproteins.
Topics: Animals; Carbon Isotopes; Centrifugation, Zonal; Dactinomycin; Depression, Chemical; Lipoproteins; Liver; Lysine; Male; Orotic Acid; Perfusion; Proteins; Rats; Templates, Genetic; Tritium | 1968 |
Effect of dietary tryptophan on hepatic polyribosomes and protein synthesis in fasted mice.
Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Diet; Fasting; Female; In Vitro Techniques; Isoleucine; Leucine; Liver; Methionine; Mice; Microsomes; Orotic Acid; Phenylalanine; Protein Biosynthesis; Ribosomes; RNA; Threonine; Time Factors; Tryptophan | 1968 |
Effect of aflatoxin on transcription in liver cell.
Topics: Aflatoxins; Animals; Carbon Isotopes; Dactinomycin; DNA; DNA Nucleotidyltransferases; In Vitro Techniques; Liver; Male; Micrococcus; Orotic Acid; Rats; RNA; RNA Nucleotidyltransferases; Templates, Genetic; Thymidine; Tritium | 1968 |
[Effects of actinomycin D on the cellular components and on RNA metabolism in oocytes of the sea urchin (Paracentrotus lividus). Autoradiographic study].
Topics: Animals; Arginine; Autoradiography; Cell Nucleus; Cytoplasm; Dactinomycin; Echinodermata; Germ Cells; Microscopy; Microscopy, Electron; Orotic Acid; RNA; Tritium | 1968 |
Regulation of ferritin synthesis in rat liver.
Topics: Animals; Antigens; Carbon Isotopes; Chlorides; Dactinomycin; Dextrans; Ferritins; Horses; Immune Sera; Intestinal Mucosa; Iron; Iron Isotopes; Kidney; Lactates; Leucine; Liver; Male; Molecular Biology; Orotic Acid; Precipitin Tests; Rabbits; Rats; Spleen; Stimulation, Chemical; Sulfates; Testis | 1968 |
Rapidly labelled high molecular RNA from rat liver.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Liver; Male; Orotic Acid; Phosphorus Isotopes; Rats; RNA; Surface-Active Agents; Time Factors; Tritium | 1968 |
Stimulation of fatty acid synthesis in vitro by gonadotrophin-induced testicular ribonucleic acid.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gas; Coenzyme A; Dactinomycin; Depression, Chemical; Enzyme Induction; Fatty Acids; Follicle Stimulating Hormone; Hypophysectomy; In Vitro Techniques; Luteinizing Hormone; Male; Microsomes; Orotic Acid; Pituitary Gland; Protein Biosynthesis; Protein Denaturation; Puromycin; Rats; RNA; RNA, Messenger; Testis; Tritium | 1968 |
Methylation of ribosomal RNA precursor and tRNA in rat liver.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Paper; Cytoplasm; Dactinomycin; Depression, Chemical; Kinetics; Liver; Methionine; Methylation; Orotic Acid; Rats; Ribosomes; RNA; RNA, Transfer; Tritium; Ultrasonics | 1968 |
Stimulation of pisatin production in Pisum sativum by actinomycin D and other compounds.
Topics: Carbon Isotopes; Dactinomycin; Enzyme Induction; Flavonoids; Leucine; Nucleosides; Orotic Acid; Phenylalanine; Plants; Protein Biosynthesis; RNA | 1968 |
Differential effects of actinomycin D on nucleic acid and protein synthesis in rat liver.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Leucine; Liver; Male; Orotic Acid; Protein Biosynthesis; Rats; RNA; Tritium | 1968 |
Changes in nuclear RNA of brain induced by olfaction in catfish.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Cell Nucleus; Chromatography; Chromatography, Ion Exchange; Cytoplasm; Dactinomycin; DNA; Electroencephalography; Electrophysiology; Fishes; Limbic System; Morpholines; Nucleotides; Odorants; Orotic Acid; RNA; Smell; Spectrophotometry | 1968 |
The rapid acceleration of hepatic nuclear ribonucleic acid breakdown by actinomycin but not by ethionine.
Topics: Adenine; Animals; Carbon Isotopes; Dactinomycin; Ethionine; Liver; Methionine; Orotic Acid; Rats; RNA | 1968 |
Amino acid incorporation into proteins in isolated rat liver nuclei.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Chloramphenicol; Chromosomes; Cycloheximide; Dactinomycin; Deoxyribonucleases; Depression, Chemical; Hydrogen-Ion Concentration; Leucine; Liver; Male; Membranes; Nucleoproteins; Orotic Acid; Peptide Biosynthesis; Puromycin; Rats; Ribonucleases; RNA | 1968 |
Injury and plasma protein biosynthesis. I. Hepatic nucleic acid metabolism.
Topics: Animals; Blood Proteins; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA; Glycoproteins; Hepatectomy; Laparotomy; Liver; Liver Regeneration; Male; Mucoproteins; Orotic Acid; Quaternary Ammonium Compounds; Rats; RNA; RNA Nucleotidyltransferases; Serum Albumin; Thymidine; Time Factors; Tritium; Wounds and Injuries | 1968 |
Injury and plasma protein biosynthesis. II. Hepatic microsomal activity and polysomal organization.
Topics: Animals; Blood Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Depression, Chemical; Hydrogen-Ion Concentration; Laparotomy; Leucine; Liver; Male; Microsomes; Orotic Acid; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; RNA; Time Factors; Wounds and Injuries | 1968 |
Effect of the administration of xanthine on the appearance of xanthine oxidase activity in the liver of growing rats.
Topics: Aging; Animals; Carbon Isotopes; Cortisone; Cycloheximide; Dactinomycin; Leucine; Liver; Orotic Acid; Phenylalanine; Rats; RNA; Xanthine Oxidase; Xanthines | 1968 |
Glucocorticoid control of nuclear synthesis and of microsomal hydrolysis of ribonucleic acid and its possible significance in the hormonal response of liver.
Topics: Animals; Animals, Newborn; Carbon Isotopes; Cell Nucleus; Chloromercuribenzoates; Cortisone; Dactinomycin; Liver; Male; Microsomes; Orotic Acid; Perfusion; Phosphotransferases; Puromycin; Rats; Ribonucleases; RNA | 1968 |
Ribosomal subunits of Landschütz ascites cells during changes in polysome distribution.
Topics: Amino Acids; Animals; Ascitic Fluid; Carbon Isotopes; Centrifugation, Density Gradient; Culture Media; Culture Techniques; Dactinomycin; Female; Liver; Male; Mice; Neoplasms, Experimental; Orotic Acid; Peritoneum; Rats; Ribosomes; Surface-Active Agents; Tritium; Ultracentrifugation; Uridine | 1968 |
Effects of cortisone and actinomycin-D upon pyrimidine nucleotide and RNA metabolism in rat liver.
Topics: Animals; Cell Nucleus; Cortisone; Dactinomycin; Depression, Chemical; Drug Synergism; Hydrogen-Ion Concentration; Liver; Male; Microsomes; Mitochondria, Liver; Nucleotides; Orotic Acid; Pyrimidines; Rats; RNA; Solubility; Stimulation, Chemical; Time Factors; Tritium; Uracil Nucleotides | 1969 |
Morphologic and metabolic alterations in hepatic cell nucleoli induced by varying doses of actinomycin D.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Cytoplasm; Dactinomycin; Depression, Chemical; DNA; Female; Injections, Intraperitoneal; Liver; Microscopy, Electron; Orotic Acid; Rats; RNA | 1969 |
Induction of partial nucleolar segregation in hepatic parenchymal cells by actinomycin D following inhibition of ribonucleic acid synthesis by ethionine.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Dactinomycin; Ethionine; Female; Liver; Microscopy, Electron; Orotic Acid; Rats; RNA; Time Factors | 1969 |
Studies on ornithine decarboxylase activity in normal and regenerating livers.
Topics: Acetates; Amides; Amino Acids; Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Caseins; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Male; Ornithine; Orotic Acid; Puromycin; Radiation Effects; Rats; Ribosomes; RNA; Time Factors | 1969 |
Effect of growth hormone on ribonucleic acid metabolism. 3. Nature and characteristics of nuclear subfractions stimulated by hormone treatment.
Topics: Animals; Cell Nucleus; Chemistry Techniques, Analytical; Dactinomycin; Growth Hormone; In Vitro Techniques; Liver; Orotic Acid; Rats; Ribosomes; RNA; RNA, Messenger | 1964 |
Influence of inhibitors of protein synthesis on interferon formation in mice.
Topics: Animals; Antimetabolites; Carbon Isotopes; Dactinomycin; In Vitro Techniques; Interferons; Leucine; Liver; Mice; Orotic Acid; Protein Biosynthesis; Puromycin | 1965 |
Effect of inhibition of RNA synthesis on neural information storage.
Topics: Animals; Behavior, Animal; Brain Chemistry; Carbon Isotopes; Dactinomycin; Electroshock; Male; Mannitol; Memory; Mice; Orotic Acid; Psychopharmacology; Radiometry; RNA | 1965 |
Stimulation of ribonucleic acid synthesis by steroid hormones. II. High molecular weight components.
Topics: Animals; Dactinomycin; Hydrocortisone; In Vitro Techniques; Liver; Male; Orotic Acid; Rats; Ribosomes; RNA; Seminal Vesicles; Testosterone | 1965 |
Aflatoxin: a site of action in the rat liver cell.
Topics: Aflatoxins; Animals; Cattle; Dactinomycin; DNA; Leucine; Liver; Orotic Acid; Oxidoreductases; Rats; RNA; Thymus Gland | 1966 |
The mechanism of dietary alterations in rat hepatic xanthine oxidase levels.
Topics: Animals; Dactinomycin; Dietary Proteins; Fluorouracil; In Vitro Techniques; Leucine; Liver; Orotic Acid; Puromycin; Rats; RNA; Xanthine Oxidase | 1966 |
Ribonucleic acid synthesis during the early action of thyroid hormones.
Topics: Animals; Cycloheximide; Dactinomycin; Fluorouracil; In Vitro Techniques; Liver; Nucleotidyltransferases; Orotic Acid; Phenylalanine; Phosphates; Polynucleotides; Puromycin; Rats; Ribosomes; RNA; Thyroidectomy; Thyroxine; Triiodothyronine | 1966 |
Nogalamycin effects in rat liver: inhibition of tryptophan pyrrolase induction and nucleic acid biosynthesis.
Topics: Animals; Anti-Bacterial Agents; Carbon Isotopes; Dactinomycin; DNA; Enzymes; Female; Hepatectomy; Hydrocortisone; Leucine; Liver; Liver Regeneration; Orotic Acid; Oxygenases; Protein Biosynthesis; Rats; RNA; Streptomyces; Thymidine; Toxins, Biological; Tritium; Tryptophan Oxygenase | 1966 |
Synthesis of 28-S RNA in the nucleolus.
Topics: Animals; Cell Nucleolus; Centrifugation, Density Gradient; Dactinomycin; In Vitro Techniques; Kinetics; Liver; Orotic Acid; Rats; RNA | 1966 |
Studies on the ribonucleic acid components of the nuclear ribonucleoprotein network.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Dactinomycin; Liver; Male; Orotic Acid; Phosphorus Isotopes; Rats; RNA; Ultracentrifugation | 1966 |
Effect of actinomycin on cardiac ribosomes and polysomes.
Topics: Amino Acids; Animals; Dactinomycin; In Vitro Techniques; Muscle Proteins; Myocardium; Orotic Acid; Rats; Ribosomes; RNA | 1966 |
Studies on ribonucleic acid synthesis in tadpole liver during metamorphosis induced by thyroxine. I. Relation of synthesis of ribonucleic acid and of carbamyl phosphate synthetase.
Topics: Animals; Anura; Dactinomycin; Enzyme Induction; In Vitro Techniques; Ligases; Liver; Metamorphosis, Biological; Orotic Acid; RNA; Thyroxine | 1967 |
Turnover of 45 S RNA of regenerating liver and Walker tumor.
Topics: Animals; Carcinoma 256, Walker; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; In Vitro Techniques; Liver; Liver Regeneration; Orotic Acid; Rats; RNA | 1967 |
Rates of turnover of deoxythymidine kinase and of its template RNA in regenerating and control liver.
Topics: Animals; Antifungal Agents; Cycloheximide; Dactinomycin; Hepatectomy; In Vitro Techniques; Leucine; Liver; Liver Regeneration; Orotic Acid; Phosphotransferases; Rats; RNA; RNA, Messenger; Transferases | 1967 |
Degradation of RNA in liver of rats treated with actinomycin D.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Injections, Intravenous; Liver; Male; Orotic Acid; Rats; RNA; Sodium Chloride | 1967 |
Physiology of rat-liver polysomes. The stability of messenger ribonucleic acid and ribosomes.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chemical Precipitation; Chromosomes; Cytoplasm; Dactinomycin; Diet; Female; Injections, Intraperitoneal; Leucine; Liver; Orotic Acid; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Spectrophotometry; Starvation; Trichloroacetic Acid; Ultracentrifugation | 1967 |
Epidermal growth factor. I. The stimulation of protein and ribonucleic acid synthesis in chick embryo epidermis.
Topics: Animals; Carbon Isotopes; Chick Embryo; Culture Techniques; Dactinomycin; Growth Substances; Lysine; Orotic Acid; Protein Biosynthesis; Proteins; Puromycin; RNA; Skin; Submandibular Gland; Thymidine; Uridine | 1967 |
The effects of some auxins on the levels of phosphate esters in Avena sativa coleoptile sections.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbon Isotopes; Dactinomycin; Edible Grain; In Vitro Techniques; Indoleacetic Acids; Orotic Acid; Phosphates; Phosphorus Isotopes; Plant Growth Regulators; RNA; Uracil Nucleotides | 1967 |
Induction of RNA and protein synthesis in the action of aldosterone in the rat.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Cortisone; Creatinine; Dactinomycin; Desoxycorticosterone; Diet; Estradiol; Fludrocortisone; In Vitro Techniques; Kidney; Leucine; Male; Methylprednisolone; Natriuresis; Orotic Acid; Potassium; Progesterone; Protein Biosynthesis; Rats; RNA; Tritium | 1967 |
Studies of permeability, RNA and protein turnover during ageing of fruit and leaf tissues.
Topics: Aging; Cell Membrane Permeability; Dactinomycin; Fruit; Leucine; Orotic Acid; Plant Growth Regulators; Plant Proteins; Plants, Edible; RNA | 1967 |
The effect of bovine growth hormone on formation of RNA by rat liver slices.
Topics: Animals; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Dactinomycin; Female; Growth Hormone; Hypophysectomy; Liver; Orotic Acid; Rats; Ribosomes; RNA; RNA, Transfer; Tritium | 1967 |
Early effects of parathyroid hormone and thyrocalcitonin on bone in organ culture.
Topics: Animals; Biological Transport; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Calcium Isotopes; Carbon Isotopes; Culture Techniques; Dactinomycin; Drug Antagonism; Female; Orotic Acid; Parathyroid Hormone; Pregnancy; Rats; RNA; Tritium; Uridine | 1967 |
Biosynthesis of RNA in slices of guinea pig cerebral cortex.
Topics: Adenine; Animals; Carbon Isotopes; Cerebral Cortex; Chromatography, Thin Layer; Dactinomycin; Electrophoresis; Guinea Pigs; In Vitro Techniques; Orotic Acid; Paper; Phosphorus Isotopes; RNA; Tritium; Uracil; Uracil Nucleotides; Uridine | 1967 |
[Effect of Actinomycin D on the incorporation of 6-C14 orotic acid into RNA during oxygen adaptation of yeast].
Topics: Carbon Isotopes; Dactinomycin; Orotic Acid; Oxygen Consumption; RNA; Saccharomyces | 1967 |
Stimulating actions on ribonucleic acid biosynthesis of aconitines, diterpenic alkaloids of Aconitum roots.
Topics: Aconitine; Aconitum; Alkaloids; Animals; Dactinomycin; Diterpenes; DNA-Directed RNA Polymerases; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred Strains; Orotic Acid; Plants, Medicinal; Rats; Rats, Inbred Strains; Ribonucleases; RNA | 1984 |
[Comparison of the effects of actinomycin D on RNA synthesis of young and adult regenerating planarians].
Topics: Animals; Dactinomycin; Kinetics; Orotic Acid; Planarians; Regeneration; Ribonucleotides; RNA; Turbellaria | 1980 |
Release of newly synthesized nucleoplasmic ribosomal subunits or their precursor particles from isolated nuclei of regenerating rat liver.
Topics: Animals; Cell Nucleus; Dactinomycin; Kinetics; Leucine; Liver; Liver Regeneration; Molecular Weight; Orotic Acid; Rats; Ribosomes; RNA | 1980 |
Effect of rabbit spermatozoa on the incorporation of labeled precursors into endometrial macromolecules.
Topics: Animals; Bucladesine; Carbonic Anhydrases; Cycloheximide; Dactinomycin; Endometrium; Female; Leucine; Male; Orotic Acid; Protein Biosynthesis; Rabbits; RNA; Spermatozoa | 1980 |
[Programs for the radiation and drug treatment of metastases of Ewing's sarcoma to the lungs in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carubicin; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Gamma Rays; Humans; Lung Neoplasms; Melphalan; Methotrexate; Orotic Acid; Prednisolone; Radiotherapy Dosage; Sarcoma, Ewing; Time Factors; Vincristine | 1983 |
Multiple sites of control of glutathione S-transferase P1-1 in rat liver.
Topics: Animals; Cell Nucleus; Dactinomycin; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Isoenzymes; Kinetics; Lead; Liver; Male; Nitrates; Orotic Acid; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; RNA Processing, Post-Transcriptional; RNA, Messenger; Time Factors; Transcription, Genetic | 1994 |
Cycloheximide sensitivity of orotic acid biosynthesis induced by ammonia and glycine administration.
Topics: Ammonium Chloride; Animals; Carbamyl Phosphate; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Glycine; Isoxazoles; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Models, Biological; Ornithine Decarboxylase; Orotic Acid; Rats; Rats, Inbred F344 | 1998 |
FURTHER STUDIES ON THE EFFECTS OF CORTISONE ON THE RIBONUCLEIC ACID METABOLISM IN RAT LIVER.
Topics: Adrenalectomy; Carbon Isotopes; Cortisone; Dactinomycin; Liver; Orotic Acid; Peptide Hydrolases; Proteins; Rats; Research; RNA; Tryptophan | 1963 |
MESSENGER RIBONUCLEIC ACID OF RAT LIVER CYTOPLASM.
Topics: Centrifugation; Cytoplasm; Dactinomycin; Liver; Metabolism; Nucleoproteins; Orotic Acid; Pharmacology; Phosphates; Phosphorus Isotopes; Proteins; Rats; Research; Ribosomes; RNA; RNA, Messenger; Tritium | 1964 |
INSULIN STIMULATION OF GLYCOGEN SYNTHESIS IN THE ISOLATED RAT DIAPHRAGM IN THE ABSENCE AND IN THE PRESENCE OF PUROMYCIN AND ACTINOMYCIN D.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Carbohydrate Metabolism; Carbon Isotopes; Dactinomycin; Diaphragm; Glucose; Glucosyltransferases; Glycogen; Insulin; Muscles; Orotic Acid; Oxidation-Reduction; Pharmacology; Proteins; Puromycin; Rats; Research; RNA | 1964 |
THE STABILITY OF LIVER MESSENGER RNA.
Topics: Carbon Isotopes; Cell Nucleus; Cytoplasm; Dactinomycin; DNA; Escherichia coli; Leucine; Liver; Mitochondria; Orotic Acid; Pharmacology; Phenylalanine; Proteins; Rats; Research; RNA; RNA, Bacterial; RNA, Messenger; Valine | 1964 |
METABOLISM OF NUCLEOLAR RIBONUCLEIC ACID AFTER PARTIAL HEPATECTOMY.
Topics: Amides; Carbon Isotopes; Cell Nucleus; Dactinomycin; Hepatectomy; Liver; Liver Diseases; Liver Regeneration; Metabolism; Orotic Acid; Pharmacology; Phenylalanine; Photometry; Puromycin; Rats; Research; RNA; Sulfhydryl Compounds | 1964 |
INDUCTION OF ENZYMATIC ACTIVITY BY INDOLYL-3-ACETIC ACID AND ITS DEPENDENCE ON SYNTHESIS OF RIBONUCLEIC ACID.
Topics: Amino Acids; Aspartic Acid; Benzoates; Carbon Isotopes; Chromatography; Dactinomycin; Indoleacetic Acids; Leucine; Metabolism; Orotic Acid; Proteins; Puromycin; Radiometry; Research; RNA; RNA, Messenger | 1964 |
MAMMALIAN ENZYME INDUCTION BY HYDROCORTISONE: THE POSSIBLE ROLE OF RNA.
Topics: Dactinomycin; Enzyme Induction; Hydrocortisone; Liver; Orotic Acid; Pharmacology; Proteins; Rats; Research; RNA; RNA, Messenger; Transaminases; Valine | 1964 |
CORRELATION OF GLUCOCORTICOID-INDUCED SYNTHESIS OF HEPATIC GLUCONEOGENIC ENZYMES WITH AMINO ACID LEVEL AND RNA METABOLISM.
Topics: Amino Acids; Dactinomycin; Fructose-Bisphosphatase; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; L-Lactate Dehydrogenase; Lipogenesis; Liver; Liver Glycogen; Malate Dehydrogenase; Nitrogen; Orotic Acid; Pharmacology; Proteins; Rats; Research; RNA; Triamcinolone | 1964 |
STUDIES ON THE INDUCTION AND REPRESSION OF ENZYMES IN RAT LIVER. I. INDUCTION OF THREONINE DEHYDRASE AND ORNITHINE-DELTA-TRANSAMINASE BY ORAL INTUBATION OF CASEIN HYDROLYSATE.
Topics: Adrenalectomy; Caseins; Dactinomycin; Hydro-Lyases; Intubation; Liver; Ornithine; Orotic Acid; Pharmacology; Protein Hydrolysates; Puromycin; Rats; Research; Threonine; Threonine Dehydratase; Transaminases | 1964 |
CORTISOL-INDUCED INCREASE OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE IN THE ISOLATED PERFUSED RAT LIVER AND ITS RELATION TO RIBONUCLEIC ACID SYNTHESIS.
Topics: Blood; Chloramphenicol; Dactinomycin; Ethionine; Hydrocortisone; Ketoglutaric Acids; Liver; Metabolism; Mitomycin; Mitomycins; Nucleotidyltransferases; Orotic Acid; Perfusion; Pharmacology; Puromycin; Rats; Research; RNA; Transaminases; Tyrosine; Tyrosine Transaminase | 1964 |
STUDIES ON THE "INDEPENDENCE" OF NUCLEOLAR RIBONUCLEIC ACID SYNTHESIS.
Topics: Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Dactinomycin; Liver; Metabolism; Orotic Acid; Pharmacology; Rats; Research; RNA | 1964 |
ROLE OF ENZYMES IN HOMEOSTASIS. VII. EARLY EFFECTS OF CORTICOSTEROID HORMONES ON HEPATIC GLUCONEOGENIC ENZYMES, RIBONUCLEIC ACID METABOLISM, AND AMINO ACID LEVEL.
Topics: Adrenal Cortex Hormones; Amino Acids; Body Weight; Cortisone; Dactinomycin; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Homeostasis; Liver; Liver Glycogen; Metabolism; Nitrogen; Organ Size; Orotic Acid; Pharmacology; Rats; Research; RNA; Triamcinolone | 1965 |
INSULIN: SUPPRESSOR OF BIOSYNTHESIS OF HEPATIC GLUCONEOGENIC ENZYMES.
Topics: Animals; Blood Glucose; Dactinomycin; Diabetes Mellitus, Experimental; Enzyme Repression; Ethionine; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Injections; Injections, Intraperitoneal; Insulin; Ligases; Liver; Metabolism; Orotic Acid; Pharmacology; Puromycin; Rats; Research; RNA; Triamcinolone | 1965 |
ACTINOMYCIN D. EFFECTS ON NUCLEIC ACID AND PROTEIN METABOLISM IN INTACT AND REGENERATING LIVER OF RATS.
Topics: Carbon Isotopes; Colorimetry; Dactinomycin; DNA; Leucine; Liver; Liver Regeneration; Metabolism; Nucleic Acids; Orotic Acid; Pathology; Peroxidases; Pharmacology; Proteins; Radiometry; Rats; Research; RNA; Thymidine; Toxicology | 1965 |
SYNTHESIS OF RIBOSOMES IN THE LIVER AFTER PARTIAL HEPATECTOMY.
Topics: Carbon Isotopes; Dactinomycin; DNA; Hepatectomy; Liver; Liver Circulation; Metabolism; Nucleotidyltransferases; Orotic Acid; Pharmacology; Phenylalanine; Physiology; Radiometry; Rats; Research; Ribosomes; RNA | 1965 |
A STUDY OF THE SYNTHESIS AND INTERRELATIONSHIPS OF RIBONUCLEIC ACIDS IN DUCK ERYTHROCYTES.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation; Chemical Precipitation; Cytoplasm; Dactinomycin; Ducks; Erythrocytes; Formates; Metabolism; Nucleosides; Orotic Acid; Pharmacology; Poultry; Radiometry; Research; RNA; Spectrum Analysis | 1965 |
EFFECT OF INSULIN ON THE ISOLATED RAT DIAPHRAGM IN THE PRESENCE AND IN THE ABSENCE OF PUROMYCIN AND ACTINOMYCIN D.
Topics: Blood Glucose; Carbohydrate Metabolism; Dactinomycin; Diaphragm; Glucose; Glycogen; Insulin; Muscles; Orotic Acid; Pharmacology; Puromycin; Rats; Research; RNA; Xylose | 1965 |
[ANTIBIOTICS AS INHIBITORS OF RNA BIOSYNTHESIS IN NEOPLASTIC TISSUE. INCORPORATION OF 2-C-14 OROTIC ACID INTO THE RNA OF EHRLICH CARCINOMA IN VARIOUS CONCENTRATIONS OF ACTINOMYCIN D].
Topics: Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Dactinomycin; Dermatologic Agents; Neoplasms; Orotic Acid; Research; RNA; RNA, Neoplasm | 1964 |
THE PORTAL VEIN AND THE CONTROL OF LIVER RIBONUCLEIC ACID METABOLISM.
Topics: Adrenalectomy; Carbon Isotopes; Dactinomycin; Hepatectomy; Liver; Metabolism; Nephrectomy; Nucleosides; Nucleotides; Nucleotidyltransferases; Orotic Acid; Portal Vein; Rats; Research; Ribose; RNA; Sodium Chloride; Tritium | 1965 |
The influence of actinomycin K on the incorporation of orotic acid-C-14 into rat tissues.
Topics: Animals; Antineoplastic Agents; Dactinomycin; Orotic Acid; Rats | 1962 |
Alterations in pyrimidine nucleotide metabolism as an early signal during the execution of programmed cell death in tobacco BY-2 cells.
Topics: Apoptosis; Dactinomycin; Hydrogen Peroxide; Nicotiana; Nitric Oxide; Orotic Acid; Phosphotransferases (Alcohol Group Acceptor); Pyrimidine Nucleotides; Signal Transduction; Thymidine; Time Factors; Transferases; Uracil; Uridine | 2004 |