dactinomycin and novobiocin

dactinomycin has been researched along with novobiocin in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199017 (44.74)18.7374
1990's11 (28.95)18.2507
2000's3 (7.89)29.6817
2010's7 (18.42)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Barrows, LR; Ireland, CM; Kokoshka, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bavari, S; Bowlin, TL; Houseweart, C; Moir, DT; Opperman, TJ; Panchal, RG; Peet, NP; Williams, JD1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Ekins, S; Williams, AJ; Xu, JJ1
Martins, T; Melo, IS; Queiroz, SCN; Reyes, FGR; Schinke, C1
Tsuji, K1
Maruo, B; Nishikawa, Y1
Lanskaia, LN; Zhukova, RA1
DeMarini, DM; Lawrence, BK2
Holbrook, NJ; Luethy, JD1
Afanas'ev, VN; Matylevich, NP; Pechatnikhov, VA; Saenko, AS; Smirnov, SG; Synzynys, BI; Zamulaeva, IA1
Desrosiers, R; Tanguay, RM1
Jones, PA; Liu, L; Nyce, J1
Borst, P; Laird, PW; ten Asbroek, AL1
Cheng, KJ; Costerton, JW; MacAlister, T; Sanderson, KE1
Cohen, M; Fagan, G; Panos, C1
Russell, AD1
Boylen, KL; Brock, TD1
Bil'trikova, AA; Egorov, NS; Toropova, EG1
Matsuzawa, H1
Madoc-Jones, H; Mauro, F1
Kleppe, K; Lossius, I; Sandlie, I; Sjåstad, K1
Fox, N; Studzinski, GP1
Marquardt, H; Schaefer, A; Stöcker, U1
Forterre, P; Gadelle, D1
Wu, MH; Yung, BY1
Shuman, S1
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R1
Phan, TN; Tuteja, N1
Cross, M; Erbes, M; Hansch, M; Hauschildt, S; Pfister, M; Thiele, A1
Lilly, JW; Maul, JE; Stern, DB1
GALE, EF1
Adachi, Y; Fujita, Y; Hirooka, K; Inaoka, T; Kim, JY; Matsuoka, H; Murata, M; Ochi, K; Ohki, R1
Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R1

Reviews

5 review(s) available for dactinomycin and novobiocin

ArticleYear
Antibacterial Compounds from Marine Bacteria, 2010-2015.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: Actinobacteria; Anti-Bacterial Agents; Bacteria; Macrolides; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017
The mechanism of action of some antibacterial agents.
    Progress in medicinal chemistry, 1969, Volume: 6

    Topics: Amino Acids; Anti-Bacterial Agents; Bacitracin; Bacteria; Cell Membrane; Cell Wall; Cephalosporins; Chloramphenicol; Cycloserine; Dactinomycin; Edetic Acid; Lysostaphin; Metals; Mitomycins; Mucoproteins; Muramidase; Nalidixic Acid; Novobiocin; Nucleic Acids; Penicillins; Peptide Biosynthesis; Phenols; Polymyxins; Puromycin; Quaternary Ammonium Compounds; Ristocetin; Streptomycin; Tetracycline; Vancomycin

1969
[Physiological role of antibiotics in the biological activity of their producers].
    Antibiotiki, 1970, Volume: 15, Issue:7

    Topics: Actinomyces; Anti-Bacterial Agents; Bacitracin; Bacteria; Chloramphenicol; Dactinomycin; Depression, Chemical; Fermentation; Novobiocin; Oxygen Consumption; Oxytetracycline; Stimulation, Chemical; Streptomyces; Streptomycin; Tyrothricin

1970
[Genetics of bacterial cell wall].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1971, Volume: 16, Issue:9

    Topics: Anti-Bacterial Agents; Bacteria; Bacteriophages; Cell Membrane; Cell Wall; Chromosome Mapping; Dactinomycin; Escherichia coli; Genetics, Microbial; Glucosamine; Lipopolysaccharides; Mutation; Novobiocin; Penicillin Resistance; Penicillins; Peptide Biosynthesis; Polysaccharides, Bacterial; Salmonella

1971
MECHANISMS OF ANTIBIOTIC ACTION.
    Pharmacological reviews, 1963, Volume: 15

    Topics: Anti-Bacterial Agents; Bacitracin; Chloramphenicol; Cycloserine; Dactinomycin; DNA; DNA, Bacterial; Erythromycin; Humans; Novobiocin; Penicillins; Pharmacology; Polymyxins; Proteins; Puromycin; RNA; RNA, Bacterial; Streptomycin; Tetracycline

1963

Other Studies

33 other study(ies) available for dactinomycin and novobiocin

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured

1996
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Bacterial Proteins; Drug Resistance, Bacterial; Indoles; Microbial Sensitivity Tests; Mutation; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Structure-Activity Relationship; Substrate Specificity

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
High-pressure liquid chromatography of antibiotics.
    Methods in enzymology, 1975, Volume: 43

    Topics: Anti-Bacterial Agents; Bacitracin; Chromatography; Clindamycin; Dactinomycin; Daunorubicin; Erythromycin; Griseofulvin; Hydrocarbons; Kanamycin; Novobiocin; Oxytetracycline; Penicillins; Polymers; Pressure; Rifampin; Tetracycline; Virginiamycin

1975
Isolation and characterization of T-even ghost-tolerant mutants of Escherichia coli.
    Journal of bacteriology, 1976, Volume: 127, Issue:1

    Topics: Acridines; Acriflavine; Adsorption; Colicins; Coliphages; Dactinomycin; Deoxycholic Acid; Edetic Acid; Escherichia coli; Lysogeny; Muramidase; Mutation; Novobiocin; Penicillin G; Penicillin Resistance; Phenylethyl Alcohol; Radiation Effects; Sodium Dodecyl Sulfate; Ultraviolet Rays; Viral Proteins

1976
[Selective action of novobiocin on Act. levoris, the producer of levorin and levoristatin].
    Antibiotiki, 1978, Volume: 23, Issue:4

    Topics: Antifungal Agents; Candicidin; Culture Media; Dactinomycin; Dose-Response Relationship, Drug; Genetic Variation; Novobiocin; Streptomyces

1978
Prophage induction by DNA topoisomerase II poisons and reactive-oxygen species: role of DNA breaks.
    Mutation research, 1992, Volume: 267, Issue:1

    Topics: Amsacrine; Azides; Bacteriophage lambda; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Escherichia coli; Free Radicals; Hydrogen Peroxide; Lysogeny; Nalidixic Acid; Novobiocin; Oxolinic Acid; Oxygen; Paraquat; Sodium Azide; SOS Response, Genetics; Teniposide; Topoisomerase II Inhibitors; Virus Replication

1992
Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage.
    Cancer research, 1992, Jan-01, Volume: 52, Issue:1

    Topics: Chloramphenicol O-Acetyltransferase; Dactinomycin; DNA; DNA Damage; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Mutagens; Novobiocin; RNA, Messenger

1992
[DNA replication in mammalian cells after the action of physical, chemical or biological factors. VI. The recovery of DNA synthesis in a culture of irradiated cells].
    Tsitologiia, 1991, Volume: 33, Issue:8

    Topics: Animals; Cell Cycle; Cells, Cultured; Cycloheximide; Dactinomycin; DNA; DNA Replication; Flow Cytometry; Gamma Rays; HeLa Cells; Humans; L Cells; Mice; Novobiocin; Time Factors

1991
Transcriptional inhibitors affecting topoisomerase II induce changes in histone methylation patterns similar to those induced by heat shock.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Animals; Camptothecin; Cells, Cultured; Dactinomycin; Drosophila melanogaster; Ethidium; Histones; Hot Temperature; In Vitro Techniques; Methylation; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Uridine

1989
Mutagenicity of topoisomerase-active agents in bacteriophage T4.
    Teratogenesis, carcinogenesis, and mutagenesis, 1988, Volume: 8, Issue:5

    Topics: Amsacrine; Dactinomycin; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Mutation; Nalidixic Acid; Novobiocin; Oxolinic Acid; T-Phages

1988
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells.
    Nucleic acids research, 1986, May-27, Volume: 14, Issue:10

    Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Fibrosarcoma; Hydroxyurea; Methylation; Nalidixic Acid; Novobiocin

1986
Controlled turnover and 3' trimming of the trans splicing precursor of Trypanosoma brucei.
    Nucleic acids research, 1987, Dec-23, Volume: 15, Issue:24

    Topics: Animals; Cell Nucleus; Chloroquine; Dactinomycin; Novobiocin; Nucleic Acid Precursors; RNA Splicing; RNA, Messenger; Transcription, Genetic; Trypanosoma brucei brucei

1987
Permeability of lipopolysaccharide-deficient (rough) mutants of Salmonella typhimurium to antibiotics, lysozyme, and other agents.
    Canadian journal of microbiology, 1974, Volume: 20, Issue:8

    Topics: Anti-Bacterial Agents; Carbon Radioisotopes; Cell Wall; Dactinomycin; Deoxycholic Acid; Drug Resistance, Microbial; Edetic Acid; Genotype; Heptoses; Lipopolysaccharides; Microbial Sensitivity Tests; Muramidase; Mutation; Novobiocin; Permeability; Polysaccharides, Bacterial; RNA, Bacterial; Salmonella typhimurium; Spheroplasts; Transduction, Genetic; Uracil

1974
Antibiotic inhibition and binding studies with a group A streptococcal L-form.
    Journal of general microbiology, 1967, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Bacitracin; Chloramphenicol; Cycloserine; Dactinomycin; L Forms; Novobiocin; Penicillin G; Polymyxins; Puromycin; Ristocetin; Streptococcus pyogenes; Tritium; Vancomycin

1967
Presence of thermophilic bacteria in laundry and domestic hot-water heaters.
    Applied microbiology, 1973, Volume: 25, Issue:1

    Topics: Bacteria; Bacteriological Techniques; Culture Media; Dactinomycin; Hot Temperature; Laundering; Novobiocin; Penicillin Resistance; Penicillins; Water Microbiology; Water Supply

1973
Age responses of cultured mammalian cells to cytotoxic drugs.
    Cancer research, 1970, Volume: 30, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Benzocycloheptenes; Colchicine; Cricetinae; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Griseofulvin; HeLa Cells; Hydroxylamines; Hydroxyurea; Mechlorethamine; Mitosis; Naphthacenes; Nitrites; Novobiocin; Potassium; Puromycin; RNA; Sulfates; Sulfides; Uracil Mustard; Vinblastine; Vincristine

1970
Mechanism of caffeine-induced inhibition of DNA synthesis in escherichia coli.
    FEBS letters, 1983, Jan-24, Volume: 151, Issue:2

    Topics: Caffeine; Dactinomycin; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Kinetics; Nalidixic Acid; Novobiocin

1983
DNA dependence and inhibition by novobiocin and coumermycin of the nucleolar adenosine triphosphatase (ATPase) of human fibroblasts.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1982, Volume: 30, Issue:4

    Topics: Adenosine Triphosphatases; Aminocoumarins; Anti-Bacterial Agents; Cell Nucleolus; Coumarins; Dactinomycin; DNA; Fibroblasts; Humans; Kinetics; Lung; Microscopy, Electron; Novobiocin; Osmolar Concentration; Transcription, Genetic

1982
DMSO-like rapid decrease in c-myc and c-myb mRNA levels and induction of differentiation in HL-60 cells by the anthracycline antitumor antibiotic aclarubicin.
    Leukemia, 1995, Volume: 9, Issue:1

    Topics: Aclarubicin; Cell Differentiation; Cell Division; Dactinomycin; Dimethyl Sulfoxide; Doxorubicin; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; Novobiocin; Oncogenes; RNA, Messenger; Superoxides

1995
DNA intercalating drugs inhibit positive supercoiling induced by novobiocin in halophilic archaea.
    FEMS microbiology letters, 1994, Oct-15, Volume: 123, Issue:1-2

    Topics: Dactinomycin; DNA-Binding Proteins; Ellipticines; Halobacterium; Indoles; Intercalating Agents; Novobiocin; Plasmids; Topoisomerase I Inhibitors

1994
Cell cycle phase-dependent cytotoxicity of actinomycin D in HeLa cells.
    European journal of pharmacology, 1994, Apr-04, Volume: 270, Issue:2-3

    Topics: Aphidicolin; Cell Cycle; Clone Cells; Colony-Forming Units Assay; Dactinomycin; DNA; HeLa Cells; Humans; Novobiocin; Thymidine

1994
Vaccinia virus DNA ligase: specificity, fidelity, and inhibition.
    Biochemistry, 1995, Dec-12, Volume: 34, Issue:49

    Topics: Adenosine Triphosphate; Animals; Base Composition; Base Sequence; Dactinomycin; Distamycins; DNA Ligases; Enzyme Inhibitors; Ethidium; Isoenzymes; Kinetics; Mammals; Molecular Sequence Data; Novobiocin; Oligodeoxyribonucleotides; Substrate Specificity; Thionucleotides; Vaccinia virus

1995
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
    Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3

    Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors

1997
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
    Biochemical and biophysical research communications, 1998, Mar-27, Volume: 244, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum

1998
Novobiocin is a novel inducer of CD38 on cells of the myelomonocytic lineage.
    Biochimica et biophysica acta, 2002, Jan-30, Volume: 1542, Issue:1-3

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Anti-Bacterial Agents; Antigens, CD; Antigens, Differentiation; Cell Differentiation; Cell Division; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Hydroxyurea; Leukopoiesis; Membrane Glycoproteins; NAD+ Nucleosidase; Novobiocin; Transcription, Genetic; Tumor Cells, Cultured

2002
The Chlamydomonas reinhardtii organellar genomes respond transcriptionally and post-transcriptionally to abiotic stimuli.
    The Plant cell, 2002, Volume: 14, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Chlamydomonas reinhardtii; Chloroplast Proton-Translocating ATPases; Conserved Sequence; Cytochrome b Group; Cytochrome b6f Complex; Cytochromes; Cytochromes f; Dactinomycin; Dicarboxylic Acids; DNA-Directed RNA Polymerases; DNA, Chloroplast; Gene Expression Profiling; Novobiocin; Oligonucleotide Array Sequence Analysis; Organelles; Organophosphorus Compounds; Phosphates; Phylogeny; Protozoan Proteins; Rifampin; RNA, Chloroplast; Sulfates; Transcription, Genetic

2002
Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.
    Journal of bacteriology, 2009, Volume: 191, Issue:10

    Topics: Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Blotting, Northern; Dactinomycin; Drug Resistance, Multiple, Bacterial; Fusidic Acid; Gene Expression Regulation, Bacterial; Mutation; Novobiocin; Operon; Protein Binding; Streptomycin

2009
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
    Plant signaling & behavior, 2011, Volume: 6, Issue:3

    Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins

2011