dactinomycin and nifedipine

dactinomycin has been researched along with nifedipine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's6 (33.33)18.2507
2000's4 (22.22)29.6817
2010's7 (38.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Desnos, C; Laran, MP; Scherman, D1
Morán, J; Rivera-Gaxiola, M1
Gundersen, CB; Umbach, JA1
Kondo, S; Kubo, H; Morimura, T; Nakatsu, S; Takeuchi, J; Yin, D1
Nakata, R; Tsukamoto, I; Wakabayashi, M1
Kondo, S; Morimura, T; Takeuchi, J; Yin, D1
Crist, SA; Humphreys, S; Jacob, RJ; Joshi-Barve, SS; Muthukumar, S; Rangnekar, VM; Sells, SF; Wood, DP1
Ali, C; Lobner, D1
Centurión, D; Cobos-Puc, LE; González-Hernández, A; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM1

Reviews

1 review(s) available for dactinomycin and nifedipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for dactinomycin and nifedipine

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Regulation of the chromaffin granule catecholamine transporter in cultured bovine adrenal medullary cells: stimulus-biosynthesis coupling.
    Journal of neurochemistry, 1992, Volume: 59, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholinesterase; Adrenal Medulla; Animals; Biological Transport; Carbachol; Carrier Proteins; Catecholamine Plasma Membrane Transport Proteins; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Chromogranin A; Chromogranins; Colforsin; Cyclic AMP; Cycloheximide; Dactinomycin; Dopamine beta-Hydroxylase; Membrane Proteins; Membrane Transport Proteins; Nifedipine; Potassium; Protein Kinase C; Tetrabenazine; Time Factors; Tritium; Tyrosine 3-Monooxygenase

1992
Effect of potassium and N-methyl-D-aspartate on the aspartate aminotransferase activity in cultured cerebellar granule cells.
    Journal of neuroscience research, 1992, Volume: 33, Issue:2

    Topics: Analysis of Variance; Animals; Aspartate Aminotransferases; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Kinetics; Magnesium; N-Methylaspartate; Neurons; Nifedipine; Potassium; Quinoxalines; Rats; Tetrodotoxin

1992
Expression of an omega-conotoxin-sensitive calcium channel in Xenopus oocytes injected with mRNA from Torpedo electric lobe.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:15

    Topics: Animals; Barium; Cadmium; Calcium; Dactinomycin; Electric Organ; Ion Channels; Microinjections; Mollusk Venoms; Myocardium; Nifedipine; Nisoldipine; omega-Conotoxin GVIA; Oocytes; Poly A; Rats; RNA; RNA, Messenger; Torpedo; Xenopus laevis

1987
Combination therapy with cisplatin and nifedipine induces apoptosis in cisplatin-sensitive and cisplatin-resistant human glioblastoma cells.
    British journal of cancer, 1995, Volume: 71, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Calcium Channels; Cell Nucleus; Cisplatin; Cycloheximide; Dactinomycin; DNA Damage; DNA, Neoplasm; Drug Resistance; Drug Synergism; Endonucleases; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasm Transplantation; Nifedipine; Nucleosomes; Tumor Cells, Cultured

1995
Regulation of thymidylate synthase in regenerating rat liver after partial hepatectomy.
    Biochemistry and molecular biology international, 1994, Volume: 34, Issue:2

    Topics: Animals; Blotting, Northern; Cloning, Molecular; Cycloheximide; Dactinomycin; Gene Expression Regulation, Enzymologic; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Nifedipine; Phenoxybenzamine; Propranolol; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Thymidylate Synthase; Time Factors; Trifluoperazine

1994
Combination therapy with cisplatin and nifedipine inducing apoptosis in multidrug-resistant human glioblastoma cells.
    Journal of neurosurgery, 1995, Volume: 82, Issue:3

    Topics: Apoptosis; Calcium; Cisplatin; Cycloheximide; Dactinomycin; DNA Damage; Drug Resistance, Multiple; Drug Synergism; Endonucleases; Enzyme Activation; Glioblastoma; Humans; Nifedipine; Tumor Cells, Cultured

1995
Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:4

    Topics: Androgens; Animals; Apoptosis; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Gene Expression Regulation; Ionomycin; Kinetics; Male; Nifedipine; Orchiectomy; Prostate; Rats; Rats, Sprague-Dawley; Receptors, Androgen

1994
Mechanisms of bFGF and NT-4 potentiation of necrotic neuronal death.
    Brain research, 2002, Nov-01, Volume: 954, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Dactinomycin; Fibroblast Growth Factor 2; Glucose; Iron Compounds; Mice; Necrosis; Nerve Growth Factors; Neuroglia; Neurons; Nifedipine; Oxygen; Polymerase Chain Reaction; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Time Factors; Vasodilator Agents

2002
Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
    Steroids, 2011, Volume: 76, Issue:4

    Topics: 4-Aminopyridine; Adenine; Aminoglutethimide; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chlorides; Cycloheximide; Dactinomycin; Dogs; Enzyme Inhibitors; Flutamide; In Vitro Techniques; Male; Nifedipine; Nucleic Acid Synthesis Inhibitors; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Protein Synthesis Inhibitors; Quinoxalines; Testosterone; Vasodilation; Vasodilator Agents

2011