dactinomycin has been researched along with morphine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (62.50) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Badawy, AA; Evans, M | 1 |
| Maneckjee, R; Minna, JD | 1 |
| Calignano, A; Capasso, A; Persico, P; Sorrentino, L | 1 |
| Gavitt, J; Karmin, M; Smith, AA | 1 |
| Cox, BM; Osman, OH | 2 |
| Fuller, GC; Lal, H; Olshan, A; Puri, SK | 1 |
| Jóhanneson, T; Steele, WJ | 1 |
| Roberge, M; Witschi, H | 1 |
| Ginsburg, M | 1 |
| Yano, I | 1 |
| Loh, HH; Shen, FH; Way, EL | 1 |
| Cox, BM; Ginsburg, M; Osman, OH | 1 |
| Miranda, HF; Wolstenholme, WW | 1 |
| Chuang, LF; Chuang, RY; Doi, RH; Suzuki, S | 1 |
| BOUSQUET, WF; DRIEVER, CW | 1 |
| COHEN, M; KEATS, AS; KRIVOY, W; UNGAR, G | 1 |
| Itoh, T; Ohara, T; Takahashi, M | 1 |
| Capasso, A | 1 |
| Chen, F; Jing, L; Lawrence, AJ; Liang, JH; Luo, J; Qin, WJ; Zhang, M | 1 |
| Alpert, LI; Kornfeld, P; Kott, E; Norio, M; Osserman, KE; Rule, A | 1 |
1 review(s) available for dactinomycin and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
23 other study(ies) available for dactinomycin and morphine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
The effects of acute and chronic nicotine hydrogen (+)-tartrate administration and subsequent withdrawal on rat liver tryptophan pyrrolase activity and their comparison with those of morphine, phenobarbitone and ethanol.
Topics: Animals; Cycloheximide; Dactinomycin; Ethanol; Humans; Hydrocortisone; Liver; Male; Morphine; NADP; Nicotinyl Alcohol; Phenobarbital; Premedication; Pyridines; Rats; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase | 1975 |
Nonconventional opioid binding sites mediate growth inhibitory effects of methadone on human lung cancer cells.
Topics: Binding Sites; Calcium; Cell Death; Cell Division; Cell Membrane; Cyclic AMP; Cycloheximide; Dactinomycin; Growth Inhibitors; Humans; Methadone; Morphine; Naltrexone; Nicotine; Pertussis Toxin; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Stereoisomerism; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
The action of dexamethasone on electrically-induced contractions of guinea-pig isolated ileum.
Topics: Animals; Cycloheximide; Dactinomycin; Dexamethasone; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mifepristone; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Receptors, Glucocorticoid | 1991 |
Tolerance to the lenticular effects of opiates.
Topics: Animals; Dactinomycin; Drug Tolerance; Epinephrine; Female; Lens, Crystalline; Levorphanol; Methadone; Mice; Morphine; Puromycin; Reserpine | 1967 |
The role of protein synthesis inhibition in the prevention of morphine tolerance.
Topics: Animals; Brain; Carbon Isotopes; Cycloheximide; Dactinomycin; Drug Tolerance; Fluorouracil; Lysine; Mercaptopurine; Morphine; Protein Biosynthesis; Puromycin; Rats; RNA | 1969 |
Induction of hepatic drug metabolism in rats by methylchloroform inhalation.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Animals; Chloroform; Cycloheximide; Cytochromes; Dactinomycin; Enzyme Induction; Hexobarbital; In Vitro Techniques; Liver; Male; Meprobamate; Microsomes, Liver; Morphine; NADP; Protein Binding; Rats; Reflex; Zoxazolamine | 1970 |
Actinomycin D and development of tolerance to morphine analgesia in rats.
Topics: Analgesia; Animals; Dactinomycin; Drug Tolerance; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methods; Morphine; Rats; Reaction Time | 1973 |
Incorporation of uridine into ribonucleic acid in rat brain slices after 9 -tetrahydrocannabinol and cannabis.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Cannabis; Carbon Isotopes; Cerebellum; Cerebral Cortex; Dactinomycin; Dronabinol; Hypothalamus; Injections, Intraperitoneal; Male; Morphine; Phytotherapy; Pituitary Gland; Rats; RNA; Uridine | 1972 |
The biochemical pharmacology of tolerance to opioid analgesics.
Topics: Animals; Brain; Dactinomycin; Drug Tolerance; Methadone; Morphine; Nalorphine; Protein Biosynthesis; Rats | 1971 |
[Dependence on central analgesics. 1. Electron microscopic studies of the changes of the zona fasciculata of the adrenal cortex of morphine addicted rats].
Topics: Adrenal Glands; Animals; Dactinomycin; Humans; Hypophysectomy; Injections, Subcutaneous; Male; Microscopy, Electron; Mitochondria; Morphine; Morphine Dependence; Pituitary Gland; Rats | 1971 |
Inhibition of the development of tolerance to morphine in rats by drugs which inhibit ribonucleic acid or protein synthesis.
Topics: Animals; Brain; Carbon Isotopes; Cycloheximide; Dactinomycin; Depression, Chemical; Drug Tolerance; Female; Fluorouracil; Lysine; Male; Mercaptopurine; Morphine; Orotic Acid; Protein Biosynthesis; Puromycin; Rats; RNA | 1970 |
Effect of dactinomycin on the acute toxicity and brain uptake of morphine.
Topics: Animals; Blood-Brain Barrier; Body Weight; Brain; Dactinomycin; Female; Heroin; Lethal Dose 50; Male; Mice; Morphine; Permeability | 1971 |
Acute tolerance to narcotic analgesic drugs in rats.
Topics: Analgesia; Analgesics; Animals; Dactinomycin; Drug Tolerance; Female; Heroin; Injections, Intravenous; Male; Meperidine; Morphine; Narcotics; Rats | 1968 |
Testosterone and tolerance in rat vas deferens.
Topics: Animals; Castration; Cycloheximide; Dactinomycin; Drug Tolerance; Ethanol; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Testosterone; Vas Deferens | 1984 |
Morphine suppresses lymphocyte apoptosis by blocking p53-mediated death signaling.
Topics: Analgesics, Opioid; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Death; Cell Survival; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Humans; Lymphocytes; Models, Biological; Morphine; Naloxone; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Opioid, mu; Retinoblastoma Protein; Signal Transduction; Time Factors; Tumor Suppressor Protein p53 | 2003 |
STRESS-DRUG INTERACTIONS: EVIDENCE FOR RAPID ENZYME INDUCTION.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Blood; Corticosterone; Dactinomycin; Drug Interactions; Enzyme Induction; Hexobarbital; Hypophysectomy; Liver; Meprobamate; Metabolism; Morphine; Pentobarbital; Pharmacology; Phenobarbital; Physiology; Rats; Research; Stress, Physiological | 1965 |
EFFECT OF ACTINOMYCIN D ON MORPHINE TOLERANCE.
Topics: Dactinomycin; Drug Tolerance; Mice; Morphine; Peptides; Pharmacology; Proteins; Rats; Research; RNA | 1965 |
Immunosuppression by morphine-induced lymphocyte apoptosis: is it a real issue?
Topics: Annexin A5; Apoptosis; Cells, Cultured; Coculture Techniques; Dactinomycin; fas Receptor; Flow Cytometry; Humans; Immune Tolerance; Lymphocytes; Morphine; Proto-Oncogene Proteins c-bcl-2 | 2005 |
Glucocorticoids involvement in the control of CNS excitability.
Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Dactinomycin; Dexamethasone; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Male; Morphine; Motor Activity; Serotonin | 2007 |
Transcription and protein synthesis inhibitors reduce the induction of behavioural sensitization to a single morphine exposure and regulate Hsp70 expression in the mouse nucleus accumbens.
Topics: Animals; Behavior, Animal; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Hyperkinesis; Male; Mice; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Protein Synthesis Inhibitors; Time Factors | 2011 |
Studies in myasthenia gravis: cellular hypersensitivity to skeletal muscle.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antibodies; Antigens; Cell Migration Inhibition; Complement Fixation Tests; Dactinomycin; Female; Fluorescent Antibody Technique; Humans; Hypersensitivity; Immunity, Cellular; Lymphocytes; Male; Meconium; Middle Aged; Muscles; Myasthenia Gravis; Myosins; Thymectomy; Thymus Gland | 1972 |