dactinomycin has been researched along with mitoxantrone in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (32.26) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 10 (32.26) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Denny, WA; Feigon, J; Kearns, DR; Leupin, W | 1 |
| Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Akiyama, S; Baba, M; Furukawa, T; Nitanda, T; Okamoto, M; Sugimoto, Y; Wang, X | 1 |
| Bu, X; Eleftheriou, A; Hayek, C; Parmar, A; Stewart, BW; Wakelin, LP | 1 |
| Gibbons, S; Kaatz, GW; Zloh, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cold, S; Pfeiffer, P; Rose, C | 1 |
| Ashley, SE; Hardy, JR; Jones, AL; Judson, IR; Powles, TJ | 1 |
| Aloyo, MC; Morales, N; Sheardy, RD; Winkle, SA; Zambrano, TY | 1 |
| Durr, FE; White, RJ | 1 |
| Bartkowiak, J; Darzynkiewicz, Z; Kapuscinski, J; Melamed, MR | 1 |
| Davies, SL; Davies, SM; Harris, AL; Hickson, ID | 1 |
| Hamada, H; Ishida, Y; Minato, K; Ohtsu, T; Shimoyama, M; Sugimoto, Y; Tobinai, K; Tsuruo, T | 1 |
| Ganapathi, R; Grabowski, D; Israel, M; Schmidt, H; Seshadri, R | 1 |
| Baldi, A; Crespi, MD; Genovese, J; Ivanier, SE | 1 |
| Bleumink, AR; Jensen, CG; Wilson, WR | 1 |
| Himori, T; Ohnuma, T; Wakui, A | 1 |
| Holland, JF; Richardson, CL; Roboz, J | 1 |
| Behrens, CH; Behrens, DL; Chen, SF; Fredericks, JR; Kirshenbaum, MR; Papp, LM; Polkus, ST; Sipple, P; Stafford, MM; Sun, JH | 1 |
| Cotter, TG; Knox, KA; McGahon, AJ; McKenna, SL; O'Gorman, DM | 1 |
| Weiss, M | 1 |
| Holguin, MH; Morgan, CD | 1 |
| Peng, T; Wang, S; Yang, CF | 1 |
| Abe, T; Goto, J; Hishinuma, T; Kobayashi, M; Mano, N; Okada, M; Takeuchi, T; Unno, M; Yamaguchi, H | 1 |
| Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R | 1 |
| Berkowitz, RS; Elias, KM; Goldstein, DP; Horowitz, NS; Jareemit, N | 1 |
3 review(s) available for dactinomycin and mitoxantrone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Cytotoxic treatment of metastatic breast cancer. Which drugs and drug combinations to use?
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Epirubicin; Etoposide; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplasm Metastasis; Vincristine | 1992 |
Induction therapy of adult acute lymphocytic leukemia without the use of vincristine or prednisone.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Controlled Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Randomized Controlled Trials as Topic; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
1 trial(s) available for dactinomycin and mitoxantrone
| Article | Year |
|---|---|
A randomised trial comparing combination chemotherapy using mitomycin C, mitozantrone and methotrexate (3M) with vincristine, anthracycline and cyclophosphamide (VAC) in advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Female; Humans; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Mitoxantrone; Vincristine | 1991 |
27 other study(ies) available for dactinomycin and mitoxantrone
| Article | Year |
|---|---|
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 1984 |
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; CD4-Positive T-Lymphocytes; Cells, Cultured; Doxorubicin; Drug Resistance, Neoplasm; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Lamivudine; Microbial Sensitivity Tests; Neoplasm Proteins; Reverse Transcriptase Inhibitors; Zidovudine | 2003 |
Bisintercalating threading diacridines: relationships between DNA binding, cytotoxicity, and cell cycle arrest.
Topics: Acridines; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; DNA; DNA, Superhelical; Electrophoresis, Agar Gel; Flow Cytometry; G2 Phase; Guanine; Humans; Hydrogen Bonding; Intercalating Agents; Kinetics; Mitosis; Structure-Activity Relationship | 2003 |
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Enhanced reactivity of a B-Z junction for cleavage by the restriction enzyme MboI.
Topics: Base Sequence; Binding Sites; Cobalt; Dactinomycin; Deoxyribonucleases, Type II Site-Specific; DNA; Ethidium; Kinetics; Macromolecular Substances; Mitoxantrone; Molecular Sequence Data; Nucleic Acid Conformation | 1991 |
Development of mitoxantrone.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Cell Line; Chemistry, Pharmaceutical; Colonic Neoplasms; Cricetinae; Cricetulus; Dactinomycin; DNA; Doxorubicin; Drug Evaluation; Drug Synergism; Female; Heart; Humans; Intercalating Agents; Interphase; Leukemia L1210; Leukemia P388; Melanoma; Mice; Mitoxantrone; RNA; RNA, Double-Stranded; Structure-Activity Relationship | 1985 |
Selective displacement of nuclear proteins by antitumor drugs having affinity for nucleic acids.
Topics: Animals; Antineoplastic Agents; Chromatin; Dactinomycin; Doxorubicin; Ethidium; Intercalating Agents; Kinetics; Ligands; Liver; Mitoxantrone; Nuclear Proteins; Plicamycin; Rats; Rats, Nude | 1989 |
Isolation of two Chinese hamster ovary cell mutants hypersensitive to topoisomerase II inhibitors and cross-resistant to peroxides.
Topics: Amsacrine; Animals; Cell Line; Cell Survival; Cricetinae; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Female; Mitoxantrone; Mutation; Ovary; Teniposide; Topoisomerase II Inhibitors | 1989 |
Multidrug resistance in cultured human leukemia and lymphoma cell lines detected by a monoclonal antibody, MRK16.
Topics: Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Humans; Leukemia; Lymphoma; Membrane Glycoproteins; Mitoxantrone; RNA, Messenger; Tumor Cells, Cultured; Vinblastine; Vincristine; Vindesine | 1989 |
Calmodulin inhibitor trifluoperazine selectively enhances cytotoxic effects of strong vs weak DNA binding antitumor drugs in doxorubicin-resistant P388 mouse leukemia cells.
Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Dactinomycin; Daunorubicin; DNA; Doxorubicin; Drug Interactions; Drug Resistance; Leukemia P388; Leukemia, Experimental; Menogaril; Mice; Mitoxantrone; Naphthacenes; Nogalamycin; Trifluoperazine | 1985 |
Mitoxantrone affects topoisomerase activities in human breast cancer cells.
Topics: Anthraquinones; Breast Neoplasms; Cell Line; Dactinomycin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Enzyme Induction; Humans; Kinetics; Mitoxantrone; Puromycin; Topoisomerase II Inhibitors | 1986 |
Effects of amsacrine and other DNA-intercalating drugs on nuclear and nucleolar structure in cultured V79 Chinese hamster cells and PtK2 rat kangaroo cells.
Topics: Aminacrine; Aminoacridines; Amsacrine; Animals; Anthraquinones; Cell Nucleolus; Cell Nucleus; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Dactinomycin; Dipodomys; Doxorubicin; Fibroblasts; Intercalating Agents; Kidney; Microscopy, Electron; Mitoxantrone | 1985 |
[Differential cell growth inhibition and terminal differentiation induction by chemotherapeutic agents of a human acute myelogenous leukemia cell line (HL-60) in vitro].
Topics: Anthraquinones; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phagocytes; Thioguanine; Vincristine | 1984 |
Competitive fluorescence polarization study of the binding of 1,4-dihydroxy-5,8-bis[(2-[(2-hydroxyethyl) amino] ethyl]amino] 9-10-anthracenedione to DNA.
Topics: Acridine Orange; Anthracenes; Antineoplastic Agents; Binding, Competitive; Chemical Phenomena; Chemistry; Dactinomycin; Daunorubicin; DNA; DNA, Bacterial; Doxorubicin; Fluorescence Polarization; Micrococcus; Mitoxantrone | 1980 |
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Isoquinolines; KB Cells; Kinetics; Leucine; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Melanoma; Melanoma, Experimental; Mesylates; Mice; Mitoxantrone; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured; Uridine | 1994 |
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin | 2000 |
Chemotherapeutic stress mediated by certain antitumor antibiotics induces an atypical CD69+ surface phenotype in peripheral T-lymphocytes.
Topics: Antibiotics, Antineoplastic; Antibodies, Blocking; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bleomycin; Dactinomycin; Dose-Response Relationship, Drug; Humans; Immunophenotyping; Lectins, C-Type; Mannitol; Mitomycin; Mitoxantrone; Plicamycin; Spectrometry, Fluorescence; Stress, Physiological; T-Lymphocytes; Thymidine | 2002 |
Investigation on the interaction of DNA and electroactive ligands using a rapid electrochemical method.
Topics: Animals; Binding Sites; Cattle; Dactinomycin; DNA; Electrochemistry; Fishes; Intercalating Agents; Ligands; Macromolecular Substances; Male; Mitoxantrone; Models, Chemical; Protein Binding; Spermatozoa | 2003 |
Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.
Topics: Antineoplastic Agents; Camptothecin; Chenodeoxycholic Acid; Dactinomycin; Docetaxel; Fluorescent Dyes; Humans; Irinotecan; Kinetics; Lysine; Mitoxantrone; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Signal Processing, Computer-Assisted; Solute Carrier Organic Anion Transporter Family Member 1B3; Spectrometry, Fluorescence; Taxoids; Transfection | 2008 |
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins | 2011 |
EMA vs EMACO in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dactinomycin; Doxorubicin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Mitoxantrone; Multivariate Analysis; Neoplasm Staging; Pregnancy; Retrospective Studies; Vincristine | 2020 |