dactinomycin has been researched along with mevalonic acid in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (57.69) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aiyar, AS; Gopalaswamy, UV | 1 |
| Chandrasekaran, C; Cooper, AD; Ellsworth, JL | 1 |
| Bansal, N; Houle, A; Melnykovych, G | 1 |
| Barbu, V; Dautry, F | 1 |
| Bankhurst, AD; Cutts, JL; Scallen, TJ; Watson, J | 1 |
| Dugan, RE; Lakshmanan, MR; Nepokroeff, CM; Ness, GC; Porter, JW | 2 |
| Kirsten, ES; Watson, JA | 1 |
| Kandutsch, AA; Saucier, SE | 1 |
| Jakoi, L; Quarfordt, SH | 1 |
| Durr, IF; Hasan, N | 1 |
| Berndt, J; Gaumert, R; Löwel, M | 1 |
| Berndt, J; Heil, T | 1 |
| Edwards, PA; Gould, RG | 1 |
| De Matteis, F | 2 |
| Berndt, J; Gaumert, R | 1 |
| Löser, R; Moreth, W; Schliack, M | 1 |
| Keller, RK; Ness, GC; Zhao, Z | 1 |
| Kanayama, Y; Negoro, N; Okamura, M; Takeda, T; Umetani, N | 1 |
| Abe, K; Goto, D; Kuwano, M; Okimoto, T; Ono, M; Shimotsu, H; Tsujita, Y | 1 |
| Choi, JW; Jung, SE | 1 |
| Bertoglio, J; Blaie, S; Bolla, M; Boquet, P; Créminon, C; Degraeve, F; Habib, A; Lévy-Toledano, S; Quéré, I | 1 |
| Hohl, RJ; Holstein, SA; Wohlford-Lenane, CL | 1 |
| Trenin, AS | 1 |
| Maruyama, K; Morishita, E; Ohtake, S; Sekiya, A; Torishima, H | 1 |
26 other study(ies) available for dactinomycin and mevalonic acid
| Article | Year |
|---|---|
Actinomycin D-induced enhancement of ubiquinone biosynthesis in rat.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Biological Transport, Active; Cholesterol; Cycloheximide; Dactinomycin; In Vitro Techniques; Kidney; Liver; Male; Mevalonic Acid; Puromycin; Rats; Ubiquinone | 1976 |
Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells.
Topics: Acetates; Animals; Blood; Blotting, Northern; Blotting, Western; Cholesterol; Dactinomycin; DNA; DNA Probes; Electrophoresis, Polyacrylamide Gel; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lipoproteins, LDL; Liver Neoplasms, Experimental; Male; Mevalonic Acid; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains; Receptors, LDL; RNA, Neoplasm; Sterols; Tumor Cells, Cultured | 1991 |
Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents.
Topics: Cell Division; Cell Survival; Cycloheximide; Dactinomycin; Deoxyribonucleases; Dexamethasone; DNA Damage; Humans; Hydroxycholesterols; In Vitro Techniques; Leukemia, T-Cell; Lovastatin; Mevalonic Acid; Mifepristone; Nuclear Proteins; Tumor Cells, Cultured | 1991 |
Mevalonate deprivation alters the induction of fos and myc by growth factors.
Topics: Blotting, Northern; Cells, Cultured; Dactinomycin; Epidermal Growth Factor; Gene Expression; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Mevalonic Acid; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Role of mevalonic acid in the regulation of natural killer cell cytotoxicity.
Topics: Cell Line; Cell Survival; Cells, Cultured; Cholesterol; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Dolichols; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lovastatin; Mevalonic Acid; Sterols | 1989 |
Regulation of the diurnal rhythm of rat liver beta-hydroxy-beta-methylglutaryl coenzmye A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone.
Topics: Alcohol Oxidoreductases; Animals; Bucladesine; Carbon Radioisotopes; Chromatography, Paper; Circadian Rhythm; Dactinomycin; Diabetes Mellitus; Glucagon; Glutarates; Hydrocortisone; Insulin; Male; Mevalonic Acid; Microsomes, Liver; Orotic Acid; Rats; Streptozocin; Theophylline; Time Factors | 1974 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.
Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Chromatography, Thin Layer; Coenzyme A; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Glutarates; Half-Life; Kinetics; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Microsomes; Neoplasms, Experimental; Rats; Time Factors; Tritium; Ultracentrifugation | 1974 |
Prevention of cyclic and triton-induced increases in hydroxymethylglutaryl coenzyme A reductase and sterol synthesis by puromycin.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Carbon Isotopes; Chromatography, Gas; Circadian Rhythm; Coenzyme A; Dactinomycin; Depression, Chemical; Fatty Acids; Glutarates; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Male; Methods; Mevalonic Acid; Mice; Microsomes; NADP; Puromycin; Sterols; Stimulation, Chemical; Surface-Active Agents | 1969 |
The induction of hepatic cholesterol synthesis in the rat by lecithin mesophase infusions.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Carbon Dioxide; Carbon Radioisotopes; Cholesterol; Coenzyme A; Cycloheximide; Dactinomycin; Eggs; Injections, Intravenous; Liver; Male; Mevalonic Acid; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Rats; Surface Properties | 1974 |
Induction of beta-galactosidase in Lactobacillus plantarum.
Topics: Acetates; Biotin; Carbon Radioisotopes; Cell-Free System; Chloramphenicol; Chromatography, Thin Layer; Dactinomycin; Enzyme Induction; Enzyme Repression; Fructose; Galactose; Galactosidases; Glucose; Lactobacillus; Lactose; Maltose; Mannitol; Mevalonic Acid; Mitomycins; Thioglycosides | 1974 |
Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in hypophysectomized rats by L-triiodothyronine.
Topics: Alcohol Oxidoreductases; Animals; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Glutarates; Hydrocortisone; Hypophysectomy; In Vitro Techniques; Kinetics; Mevalonic Acid; Microsomes, Liver; Rats; Stimulation, Chemical; Triiodothyronine | 1973 |
[Influence of protein biosynthesis inhibitors on the circadian rhythm of hydroxymethylglutaryl-CoA-reductase in the mouse liver].
Topics: Alcohol Oxidoreductases; Animals; Cholesterol; Circadian Rhythm; Coenzyme A; Cycloheximide; Dactinomycin; Fasting; Glutarates; Liver; Mevalonic Acid; Mice; Puromycin | 1972 |
[Cholesterol biosynthesis in the mouse liver following combination of roentgen irradiation and administration of actinomycin D].
Topics: Acetates; Animals; Cholesterol; Dactinomycin; Liver; Male; Mevalonic Acid; Mice; Radiation Dosage; Radiation Effects | 1973 |
Dependence of the circadian rhythm of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A on ribonucleic acid synthesis. A possible second site of inhibition by dietary cholesterol.
Topics: Alcohol Oxidoreductases; Animals; Cholesterol; Cholesterol, Dietary; Circadian Rhythm; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Epinephrine; Glutarates; Intubation, Gastrointestinal; Male; Mevalonic Acid; Microsomes, Liver; Rats; RNA; Time Factors | 1974 |
Liver cholesterol metabolism following trauma. Evidence for increased rate of cholesterol synthesis and breakdown.
Topics: Acetates; Adrenal Glands; Adrenalectomy; Animals; Carbon Dioxide; Carbon Isotopes; Cholesterol; Dactinomycin; Depression, Chemical; Dietary Fats; Ethionine; Fatty Acids; Feedback; Hindlimb; Hypophysectomy; Ischemia; Laparotomy; Liver; Male; Mevalonic Acid; Organ Size; Pituitary Gland; Rats; Stimulation, Chemical; Thyroid Gland; Thyroidectomy; Time Factors; Wounds and Injuries | 1969 |
The in vitro biosynthesis of cholesterol and the cholesterol content in the liver of x-irradiated mice.
Topics: Acetates; Animals; Carbon Isotopes; Cholesterol; Dactinomycin; Liver; Male; Mevalonic Acid; Mice; Puromycin; Radiation Effects; Rats; Time Factors | 1970 |
Stimulation of liver cholesterol synthesis by actinomycin D.
Topics: Acetates; Adrenalectomy; Alcohol Oxidoreductases; Animals; Carbon Dioxide; Carbon Isotopes; Cholesterol; Dactinomycin; Diet; Ethionine; Fatty Acids; In Vitro Techniques; Ketone Bodies; Liver; Male; Mevalonic Acid; Puromycin; Rats; Stimulation, Chemical | 1968 |
Mode of action of terbufibrol (INN) a hypolipidemic agent on rat liver sterol synthesis.
Topics: Animals; Anticholesteremic Agents; Benzoates; Cholesterol; Circadian Rhythm; Cycloheximide; Dactinomycin; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Mevalonic Acid; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Sterols; Triglycerides | 1982 |
Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase.
Topics: Animals; Blotting, Northern; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Dactinomycin; Dimethylallyltranstransferase; Enzyme Induction; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Immunoblotting; Kinetics; Liver; Male; Mevalonic Acid; Rats; Rats, Sprague-Dawley; Receptors, LDL; RNA, Messenger; Tricarboxylic Acids | 1994 |
Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages.
Topics: Cell Line; Dactinomycin; Enzyme Inhibitors; Farnesol; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Macrophages; Membrane Proteins; Mevalonic Acid; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class B; Tetradecanoylphorbol Acetate | 1996 |
Upregulation of low density lipoprotein receptor by gemfibrozil, a hypolipidemic agent, in human hepatoma cells through stabilization of mRNA transcripts.
Topics: Carcinoma, Hepatocellular; Dactinomycin; ErbB Receptors; Gemfibrozil; Gene Expression Regulation, Neoplastic; Genes, Reporter; Half-Life; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver Neoplasms; Mevalonic Acid; Neoplasm Proteins; Pravastatin; Promoter Regions, Genetic; Receptors, LDL; RNA, Messenger; RNA, Neoplasm; Transfection; Tumor Cells, Cultured; Up-Regulation | 1997 |
Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells.
Topics: Anticholesteremic Agents; Apoptosis; Cell Division; Cell Line; Chromatin; Cycloheximide; Dactinomycin; DNA Fragmentation; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Microscopy, Electron; Microscopy, Fluorescence; Neuroglia; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
Topics: Amides; Aorta; Apoptosis; Bacterial Proteins; Bacterial Toxins; Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dactinomycin; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; Interleukin-1; Isoenzymes; Leucine; Lovastatin; Membrane Proteins; Mevalonic Acid; Muscle, Smooth; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Protein Prenylation; Pyridines; rho GTP-Binding Proteins; Time Factors | 2001 |
Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line; Cycloheximide; Dactinomycin; Humans; K562 Cells; Lovastatin; Mevalonic Acid; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Synthesis Inhibitors; rap1 GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; RNA; Time Factors; Transcription, Genetic; Up-Regulation | 2002 |
[Microbial model of Halobacterium salinarum for screening inhibitors of sterol biosynthesis].
Topics: Antibiotics, Antineoplastic; Automation, Laboratory; Bacterial Proteins; Dactinomycin; Drug Discovery; Halobacterium salinarum; High-Throughput Screening Assays; Humans; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Mevalonic Acid; Microbial Viability; Mitomycin; Sterols; Streptonigrin | 2013 |
Fluvastatin Upregulates the Expression of Tissue Factor Pathway Inhibitor in Human Umbilical Vein Endothelial Cells.
Topics: Anticoagulants; Antigens; Blotting, Western; Cells, Cultured; Chromones; Dactinomycin; Fatty Acids, Monounsaturated; Fluvastatin; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Indoles; Lipoproteins; Luciferases; Maleimides; Mevalonic Acid; Morpholines; Pyridines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2015 |