Compounds > dactinomycin

dactinomycin and methimazole

dactinomycin has been researched along with methimazole in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Sherwin, JR; Tong, W1
Isozaki, O; Kimura, S; Kohn, LD; Kozak, CA1
Bagchi, N; Brown, TR; Shivers, B1
Cohen, JD; Utiger, RD1
Bottazzi, C; Demori, I; Fugassa, E1
Calil-Silveira, J; Nunes, MT; Serrano-Nascimento, C1

Reviews

1 review(s) available for dactinomycin and methimazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for dactinomycin and methimazole

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Stimulatory actions of thyrotropin and dibutyryl cyclic AMP on transcription and translation in the regulation of thyroidal protein synthesis.
    Biochimica et biophysica acta, 1976, Apr-02, Volume: 425, Issue:4

    Topics: Animals; Bucladesine; Cattle; Dactinomycin; Deoxyadenosines; Iodides; Leucine; Methimazole; Protein Biosynthesis; Thyroid Gland; Thyrotropin; Transcription, Genetic

1976
Thyroid peroxidase: rat cDNA sequence, chromosomal localization in mouse, and regulation of gene expression by comparison to thyroglobulin in rat FRTL-5 cells.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:11

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Amanitins; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chromosome Mapping; Cycloheximide; Dactinomycin; DNA; Gene Expression Regulation; Genes; Humans; Insulin; Insulin-Like Growth Factor I; Iodide Peroxidase; Methimazole; Mice; Molecular Sequence Data; Rats; Rats, Inbred F344; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyrotropin

1989
Studies on the mechanism of acute inhibition of thyroglobulin hydrolysis by iodine.
    Acta endocrinologica, 1985, Volume: 108, Issue:4

    Topics: Ammonium Chloride; Animals; Bucladesine; Cells, Cultured; Chloroquine; Cycloheximide; Dactinomycin; Female; Hydrolysis; Iodine; Methimazole; Mice; Sodium Iodide; Thyroglobulin; Thyroid Gland; Time Factors

1985
Metastatic choriocarcinoma associated with hyperthyroidism.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:4

    Topics: Adolescent; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Hormones, Ectopic; Humans; Hydatidiform Mole; Hyperthyroidism; Methimazole; Methotrexate; Neoplasm Metastasis; Pregnancy; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine

1970
Tri-iodothyronine increases insulin-like growth factor binding protein-2 expression in cultured hepatocytes from hypothyroid rats.
    The Journal of endocrinology, 1999, Volume: 161, Issue:3

    Topics: Animals; Anisomycin; Blotting, Northern; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression; Hypothyroidism; Insulin-Like Growth Factor Binding Protein 2; Liver; Male; Methimazole; Propylthiouracil; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Triiodothyronine

1999
Iodide treatment acutely increases pendrin (SLC26A4) mRNA expression in the rat thyroid and the PCCl3 thyroid cell line by transcriptional mechanisms.
    Molecular and cellular endocrinology, 2012, Mar-05, Volume: 350, Issue:1

    Topics: Animals; Antithyroid Agents; Cell Line; Cell Proliferation; Cell Survival; Chloride-Bicarbonate Antiporters; Dactinomycin; Iodides; Male; Methimazole; Perchlorates; Pituitary Gland; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Sulfate Transporters; Thyroid Gland; Thyrotropin; Thyroxine; Transcription, Genetic; Triiodothyronine

2012