dactinomycin and metallothionein

dactinomycin has been researched along with metallothionein in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199030 (69.77)18.7374
1990's13 (30.23)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shaikh, ZA; Smith, JC1
Cousins, RJ; Feldman, SL; Squibb, KS1
Cousins, RJ; Richards, MP3
Brady, FO; Panemangalore, M1
Beall, FA; Canterbury, WJ; Hauer, EC; Sobocinski, PZ1
Bryan, SE; Hidalgo, HA; Koppa, V1
Brady, FO; Coles, BJ; Day, FA1
Cousins, RJ; Markowitz, LA; Shapiro, SG; Squibb, KS1
Premakumar, R; Rajagopalan, KV; Winge, DR1
Steinebach, OM; Wolterbeek, HT2
Sato, M1
Epner, DE; Herschman, HR1
Andrews, GK; De, SK; Enders, GC1
Goodridge, AG; McCormick, CC; Salati, LM1
Raffaniello, RD; Wapnir, RA1
Andrews, GK; Fleet, JC; McCormick, CC1
Gedamu, L; Olsson, PE; Zafarullah, M1
Akner, G; Arner, P; Brönnegård, M; Gustafsson, JA; Hellström, L1
Poirier, LA; Waalkes, MP1
Kachru, DN; Khandelwal, S; Tandon, SK1
Gedamu, L; Sadhu, C1
Klaassen, CD; Sendelbach, LE1
Daniels-McQueen, S; Smith, LL; Thach, RE; Walden, WE1
Ikebuchi, H; Suzuki, K; Terao, T; Teshima, R; Yamane, Y1
Cousins, RJ1
Cousins, RJ; DiSilvestro, RA1
Hjelle, JJ; Klaassen, CD; Waalkes, MP1
Datta, K; Prasad, AR1
Lehman, LD; Poisner, AM1
Cantilena, LR; Klaassen, CD; Waalkes, MP1
Loya, S; Olafson, RW; Sim, RG1
Klaassen, CD; Waalkes, MP; Watkins, JB1
Glauber, JG; Madaras, JG; Starcher, BC1
Canterbury, WJ; Sobocinski, PZ1
Gedamu, L; Heikkila, JJ; Iatrou, K; Schultz, GA1
Andersen, RD; Herschman, HR; Karin, M; Slater, E; Smith, K1
Enger, MD; Hildebrand, CE1
Coyle, P; Philcox, JC; Rofe, AM1
Fischer, J; Lehnert, V; Pallauf, J1
Imura, N; Naganuma, A; Nakagawa, I; Suzuki, M; Yanagiya, T1

Reviews

1 review(s) available for dactinomycin and metallothionein

ArticleYear
Relationship of metallothionein synthesis and degradation to intracellular zinc metabolism.
    Developments in toxicology and environmental science, 1982, Volume: 9

    Topics: Adrenalectomy; Animals; Cycloheximide; Dactinomycin; Dexamethasone; Gene Expression Regulation; Glucagon; Kidney; Liver; Magnesium; Metalloproteins; Metallothionein; Poly A; Rats; Ribosomes; RNA; RNA, Messenger; Zinc

1982

Other Studies

42 other study(ies) available for dactinomycin and metallothionein

ArticleYear
The mechanisms of hepatic and renal metallothionein biosynthesis in cadmium-exposed rats.
    Chemico-biological interactions, 1977, Volume: 19, Issue:2

    Topics: Animals; Cadmium; Cadmium Poisoning; Cycloheximide; Dactinomycin; Kidney; Kinetics; Liver; Male; Metalloproteins; Metallothionein; Organ Specificity; Rats; Subcellular Fractions

1977
Control of zinc-thionein synthesis in rat liver.
    The Biochemical journal, 1977, Apr-15, Volume: 164, Issue:1

    Topics: Animals; Cystine; Cytosol; Dactinomycin; Deoxyadenosines; Liver; Male; Metalloproteins; Metallothionein; Rats; Time Factors; Zinc

1977
Influence of inhibitors of protein synthesis on zinc metabolism.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 156, Issue:3

    Topics: Animals; Chloramphenicol; Cycloheximide; Cytosol; Dactinomycin; Deoxyadenosines; Intestinal Mucosa; Liver; Male; Metallothionein; Protein Biosynthesis; Rats; Zinc

1977
Induction and synthesis of metallothionein in isolated perfused rat liver.
    The Journal of biological chemistry, 1978, Nov-10, Volume: 253, Issue:21

    Topics: Animals; Cadmium; Cycloheximide; Dactinomycin; Deoxyadenosines; In Vitro Techniques; Kinetics; Liver; Male; Metalloproteins; Metallothionein; Perfusion; Protein Biosynthesis; Rats; Zinc

1978
Induction of hypozincemia and hepatic metallothionein synthesis in hypersensitivity reactions.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 160, Issue:2

    Topics: Animals; Dactinomycin; Hypersensitivity; Iron; Liver; Male; Metalloproteins; Metallothionein; Rats; Serum Albumin, Bovine; Zinc

1979
Induction of cadmium-thionein in isolated rat liver cells.
    The Biochemical journal, 1978, Feb-15, Volume: 170, Issue:2

    Topics: Animals; Cadmium; Chromatography, Liquid; Cycloheximide; Cysteine; Dactinomycin; In Vitro Techniques; Liver; Male; Metalloproteins; Metallothionein; Rats

1978
Postinductive actinomycin D effects on the concentrations of cadmium thionein, zinc thionein, and copper chelatin in rat liver.
    Bioinorganic chemistry, 1978, Volume: 8, Issue:2

    Topics: Animals; Cadmium; Copper; Dactinomycin; Kinetics; Liver; Metalloproteins; Metallothionein; Rats; Zinc

1978
Cell-free synthesis of metallothionein directed by rat liver polyadenylated messenger ribonucleic acid.
    The Biochemical journal, 1978, Dec-01, Volume: 175, Issue:3

    Topics: Animals; Cell-Free System; Chromatography, Agarose; Chromatography, Gel; Dactinomycin; In Vitro Techniques; Liver; Male; Metalloproteins; Metallothionein; Poly A; Polyribosomes; Rats; RNA, Messenger; Zinc

1978
Chemistry and biology of copper-chelatin.
    Advances in experimental medicine and biology, 1976, Volume: 74

    Topics: Amino Acids; Animals; Biological Transport; Cadmium; Chelating Agents; Copper; Cycloheximide; Dactinomycin; Liver; Male; Mercury; Metalloproteins; Metallothionein; Rats; Silver; Zinc

1976
Metallothionein and its relationship to the metabolism of dietary zinc in rats.
    The Journal of nutrition, 1976, Volume: 106, Issue:11

    Topics: Animals; Cytosol; Dactinomycin; Dose-Response Relationship, Drug; Homeostasis; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Liver; Male; Metalloproteins; Metallothionein; Protein Binding; Rats; Zinc

1976
Mammalian zinc homeostasis: requirement for RNA and metallothionein synthesis.
    Biochemical and biophysical research communications, 1975, Jun-16, Volume: 64, Issue:4

    Topics: Animals; Chromatography, Gel; Cytosol; Dactinomycin; Homeostasis; Intestinal Mucosa; Ligands; Liver; Metalloproteins; Metallothionein; Protein Biosynthesis; Rats; Receptors, Drug; RNA; RNA, Messenger; Zinc

1975
Effects of cadmium, copper and metallothionein synthesis inhibiting and stimulating compounds on zinc uptake and accumulation in rat hepatoma HTC cells.
    Chemico-biological interactions, 1992, Nov-16, Volume: 84, Issue:3

    Topics: Animals; Cadmium; Cadmium Radioisotopes; Cell Membrane; Chromatography, High Pressure Liquid; Copper; Copper Radioisotopes; Cyclic AMP; Cycloheximide; Cytosol; Dactinomycin; Dexamethasone; Liver Neoplasms, Experimental; Metallothionein; Potassium Radioisotopes; Rats; Tumor Cells, Cultured; Zinc; Zinc Radioisotopes

1992
Dose-dependent increases in metallothionein synthesis in the lung and liver of paraquat-treated rats.
    Toxicology and applied pharmacology, 1991, Volume: 107, Issue:1

    Topics: Animals; Body Weight; Dactinomycin; Dose-Response Relationship, Drug; Lipid Peroxidation; Liver; Lung; Male; Metallothionein; Organ Size; Paraquat; Rats; Rats, Inbred Strains; Superoxides; Zinc

1991
Heavy metals induce expression of the TPA-inducible sequence (TIS) genes.
    Journal of cellular physiology, 1991, Volume: 148, Issue:1

    Topics: Animals; Cadmium; Cells, Cultured; Cycloheximide; Dactinomycin; Down-Regulation; Fibroblasts; Gene Expression Regulation; Genes; Growth Substances; Metallothionein; Mice; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation; Zinc

1991
Metallothionein mRNA stability in chicken and mouse cells.
    Biochimica et biophysica acta, 1991, Oct-08, Volume: 1090, Issue:2

    Topics: Animals; Base Sequence; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Gene Expression Regulation; Metallothionein; Mice; Molecular Sequence Data; RNA, Messenger

1991
Abundance of hepatic metallothionein mRNA is increased by protein-synthesis inhibitors. Evidence for transcriptional activation and post-transcriptional regulation.
    The Biochemical journal, 1991, Jan-01, Volume: 273(Pt 1)

    Topics: Animals; Blotting, Northern; Cells, Cultured; Chick Embryo; Cycloheximide; Dactinomycin; Electrophoresis, Agar Gel; Liver; Metallothionein; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger; Transcription, Genetic; Zinc

1991
Zinc-induced metallothionein synthesis by Caco-2 cells.
    Biochemical medicine and metabolic biology, 1991, Volume: 45, Issue:1

    Topics: Animals; Cell Line; Cycloheximide; Cysteine; Dactinomycin; Intestinal Absorption; Intestinal Mucosa; Intestines; Metallothionein; Zinc

1991
Iron-induced metallothionein in chick liver: a rapid, route-dependent effect independent of zinc status.
    The Journal of nutrition, 1990, Volume: 120, Issue:10

    Topics: Animals; Chickens; Dactinomycin; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Iron; Lipopolysaccharides; Liver; Male; Metallothionein; Zinc

1990
Differential regulation of metallothionein genes in rainbow trout fibroblasts, RTG-2.
    Biochimica et biophysica acta, 1990, Jul-30, Volume: 1049, Issue:3

    Topics: Animals; Base Sequence; Blotting, Northern; Cadmium; Cadmium Chloride; Cell Line; Chlorides; Cycloheximide; Dactinomycin; Fibroblasts; Gene Expression Regulation; Kinetics; Metallothionein; Molecular Sequence Data; RNA, Messenger; Transcription, Genetic; Trout; Zinc; Zinc Compounds

1990
Glucocorticoid receptor messenger ribonucleic acid in different regions of human adipose tissue.
    Endocrinology, 1990, Volume: 127, Issue:4

    Topics: Abdomen; Adipose Tissue; Adult; Buttocks; Dactinomycin; Female; Gene Expression; Gene Expression Regulation; Humans; Hydrocortisone; Immunohistochemistry; Male; Metallothionein; Middle Aged; Nucleic Acid Hybridization; Receptors, Glucocorticoid; RNA, Messenger; Sex Characteristics

1990
Induction of hepatic metallothionein following 5-azacytidine administration.
    Toxicology and applied pharmacology, 1985, Jun-15, Volume: 79, Issue:1

    Topics: Animals; Azacitidine; Cells, Cultured; Chromatography, Gel; Chromatography, Ion Exchange; Dactinomycin; Female; Gene Expression Regulation; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1985
Influence of diethyldithiocarbamate on nickel-induced hepatic metallothionein in rats.
    Toxicology and industrial health, 1989, Volume: 5, Issue:3

    Topics: Animals; Copper; Cycloheximide; Cytosol; Dactinomycin; Ditiocarb; Dose-Response Relationship, Drug; Drug Synergism; Liver; Male; Metallothionein; Nickel; Rats; Time Factors; Zinc

1989
Metal-specific posttranscriptional control of human metallothionein genes.
    Molecular and cellular biology, 1989, Volume: 9, Issue:12

    Topics: Actins; Carcinoma, Hepatocellular; Cell Line; Copper; Cycloheximide; Dactinomycin; Gene Expression Regulation; Genes; Humans; Kinetics; Liver Neoplasms; Metallothionein; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Zinc

1989
Kidney synthesizes less metallothionein than liver in response to cadmium chloride and cadmium-metallothionein.
    Toxicology and applied pharmacology, 1988, Volume: 92, Issue:1

    Topics: Animals; Cadmium; Cadmium Chloride; Dactinomycin; Kidney; Liver; Male; Metallothionein; Mice; Rats

1988
Procedures for enhancing the utility of the metallothionein promoter for the regulated expression of downstream open reading frames.
    Gene, 1987, Volume: 61, Issue:3

    Topics: Animals; Cells, Cultured; Chromosome Mapping; Cycloheximide; Dactinomycin; DNA, Recombinant; Gene Expression Regulation; Genetic Vectors; Metallothionein; Mice; Peptides; Promoter Regions, Genetic; Transcription, Genetic; Zinc

1987
Simultaneous induction of Pb-metallothionein-like protein and Zn-thionein in the liver of rats given lead acetate.
    The Biochemical journal, 1986, Jan-15, Volume: 233, Issue:2

    Topics: Amino Acids; Animals; Chromatography, Gel; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Lead; Liver; Macromolecular Substances; Male; Metallothionein; Organometallic Compounds; Rats; Rats, Inbred Strains

1986
Glucocorticoid independent mediation of interleukin-1 induced changes in serum zinc and liver metallothionein levels.
    Life sciences, 1984, Nov-19, Volume: 35, Issue:21

    Topics: Adrenalectomy; Animals; Dactinomycin; Dexamethasone; Glucocorticoids; Interleukin-1; Liver; Male; Metallothionein; Rats; Zinc

1984
Transient induction of hepatic metallothionein following oral ethanol administration.
    Toxicology and applied pharmacology, 1984, Jun-30, Volume: 74, Issue:2

    Topics: Administration, Oral; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Chromatography, Gel; Cytosol; Dactinomycin; Dose-Response Relationship, Drug; Ethanol; Intestinal Mucosa; Kidney; Liver; Male; Metallothionein; Mice; Organ Size; Pancreas; Pyrazoles; Rats; Rats, Inbred Strains

1984
Evidence for an inducible cadmium binding protein metallothionein in chick embryo.
    Biochemistry international, 1983, Volume: 7, Issue:6

    Topics: Animals; Cadmium; Chick Embryo; Dactinomycin; Liver; Lysine; Metallothionein; Protein Biosynthesis; Tritium

1983
Induction of metallothionein synthesis in cultured human trophoblasts by cadmium and zinc.
    Journal of toxicology and environmental health, 1984, Volume: 14, Issue:2-3

    Topics: Cadmium; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Female; Humans; L-Lactate Dehydrogenase; Metallothionein; Pregnancy; Time Factors; Trophoblasts; Zinc

1984
Alteration of tissue disposition of cadmium by chelating agents.
    Environmental health perspectives, 1984, Volume: 54

    Topics: Animals; Cadmium; Chelating Agents; Dactinomycin; Kidney; Liver; Male; Metallothionein; Mice; Testis; Tissue Distribution

1984
Physiological parameters of prokaryotic metallothionein induction.
    Biochemical and biophysical research communications, 1980, Aug-29, Volume: 95, Issue:4

    Topics: Cadmium; Cyanobacteria; Dactinomycin; Drug Resistance, Microbial; Metalloproteins; Metallothionein; Time Factors

1980
Minimal role of metallothionein in decreased chelator efficacy for cadmium.
    Toxicology and applied pharmacology, 1983, Volume: 68, Issue:3

    Topics: Animals; Cadmium; Cadmium Poisoning; Chelating Agents; Dactinomycin; Kidney; Liver; Metalloproteins; Metallothionein; Pentetic Acid; Rats; Rats, Inbred Strains

1983
Zinc absorption and its relationship to intestinal metallothionein.
    The Journal of nutrition, 1980, Volume: 110, Issue:7

    Topics: Animals; Dactinomycin; Duodenum; Female; Intestinal Absorption; Intestinal Mucosa; Kinetics; Male; Metalloproteins; Metallothionein; Mice; Mice, Inbred Strains; Radioisotope Dilution Technique; Zinc; Zinc Radioisotopes

1980
Hepatic metallothionein induction in inflammation.
    Annals of the New York Academy of Sciences, 1982, Volume: 389

    Topics: Animals; Blood Glucose; Dactinomycin; Endotoxins; Escherichia coli; Glucagon; Inflammation; Insulin; Liver; Male; Metalloproteins; Metallothionein; Mice; Mice, Inbred C3H; Rats; Salmonella typhimurium; Zinc

1982
Expression of a set of fish genes following heat or metal ion exposure.
    The Journal of biological chemistry, 1982, Oct-25, Volume: 257, Issue:20

    Topics: Animals; Cadmium; Cadmium Chloride; Dactinomycin; Gene Expression Regulation; Genes; Heat-Shock Proteins; Hot Temperature; Metallothionein; Metals; Protein Biosynthesis; Salmon; Time Factors; Zinc

1982
Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response.
    Nature, 1980, Jul-17, Volume: 286, Issue:5770

    Topics: Biological Transport; Cycloheximide; Dactinomycin; Dexamethasone; HeLa Cells; Humans; Metalloproteins; Metallothionein; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic; Zinc

1980
Regulation of Cd2+/Zn2+-stimulated metallothionein synthesis during induction, deinduction, and superinduction.
    Biochemistry, 1980, Dec-09, Volume: 19, Issue:25

    Topics: Animals; Calcium; Cell Line; Cricetinae; Cricetulus; Dactinomycin; Female; Metalloproteins; Metallothionein; Ovary; Protein Biosynthesis; Zinc

1980
Metallothionein induction in freshly isolated rat hepatocytes.
    Biological trace element research, 1993, Volume: 36, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Glucagon; Interleukin-1; Interleukin-6; Liver; Male; Metallothionein; Rats; Tumor Necrosis Factor-alpha; Zinc

1993
Role of cytosolic copper, metallothionein and glutathione in copper toxicity in rat hepatoma tissue culture cells.
    Toxicology, 1994, Sep-06, Volume: 92, Issue:1-3

    Topics: Animals; Bucladesine; Cadmium; Chromatography, High Pressure Liquid; Copper; Copper Radioisotopes; Cycloheximide; Dactinomycin; Dexamethasone; Glutathione; L-Lactate Dehydrogenase; Liver Neoplasms, Experimental; Metallothionein; Rats; Superoxide Dismutase; Tumor Cells, Cultured; Zinc

1994
Influence of cAMP-effector-agonists on the synthesis of metallothionein in rat primary hepatocytes.
    Zeitschrift fur Ernahrungswissenschaft, 1995, Volume: 34, Issue:4

    Topics: Analysis of Variance; Animals; Bucladesine; Butyrates; Butyric Acid; Cells, Cultured; Cyclic AMP; Dactinomycin; Epinephrine; Glucagon; Isoproterenol; Kinetics; Liver; Metallothionein; Norepinephrine; Rats; Sulfates; Theophylline; Zinc Compounds; Zinc Sulfate

1995
Effect of glutathione depletion on metallothionein synthesis induced by paraquat in mice.
    The Tohoku journal of experimental medicine, 1995, Volume: 177, Issue:3

    Topics: Animals; Antimetabolites; Blotting, Northern; Buthionine Sulfoximine; Cadmium; Chlorides; Chromatography, Gel; Chromatography, Ion Exchange; Dactinomycin; Dexamethasone; Glucocorticoids; Glutathione; Herbicides; Kidney; Liver; Male; Maleates; Metallothionein; Mice; Mice, Inbred ICR; Paraquat; Protein Synthesis Inhibitors; Zinc Compounds

1995