dactinomycin and isoniazid

dactinomycin has been researched along with isoniazid in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Devi, PB; Nallangi, R; Samala, G; Sriram, D; Yogeeswari, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blake, RL; Blake, SL; Kun, E; Loh, HH1
Le, NT; Richardson, DR1
Liang, SX; Richardson, DR1
SAMPEY, JR1
Lui, A; Znidarić, D3

Reviews

2 review(s) available for dactinomycin and isoniazid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
NEW AND OLD DRUGS IN THE MANAGEMENT OF HODGKIN'S DISEASE.
    Medical times, 1964, Volume: 92

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dexamethasone; Folic Acid Antagonists; Hodgkin Disease; Humans; Isoniazid; Mannomustine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Nitrogen Mustard Compounds; Phenylbutazone; Prednisolone; Prednisone; Thiotepa

1964

Other Studies

12 other study(ies) available for dactinomycin and isoniazid

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of 3-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel Mycobacterium tuberculosis pantothenate synthetase inhibitors.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Animals; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Molecular Structure; Mycobacterium tuberculosis; Peptide Synthases; Pyrazoles; Pyridines; Structure-Activity Relationship

2013
The effect of nicotinamide and homologs on the activity of inducible enzymes and NAD content of the rat liver.
    Molecular pharmacology, 1967, Volume: 3, Issue:5

    Topics: Animals; Brain; Dactinomycin; Enzyme Induction; Hydrocortisone; Hypophysectomy; Isoniazid; Kidney; Liver; Male; Muscles; Myocardium; NAD; Niacinamide; Nicotinic Acids; Nikethamide; Pyridines; Rats; Tryptophan Oxygenase; Tyrosine Transaminase

1967
Potent iron chelators increase the mRNA levels of the universal cyclin-dependent kinase inhibitor p21(CIP1/WAF1), but paradoxically inhibit its translation: a potential mechanism of cell cycle dysregulation.
    Carcinogenesis, 2003, Volume: 24, Issue:6

    Topics: Cell Cycle; Cells, Cultured; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Dactinomycin; Deferoxamine; DNA Damage; Gene Expression Regulation; Humans; Iron Chelating Agents; Isoniazid; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Biosynthesis; Receptors, Transferrin; RNA, Messenger; Tumor Suppressor Protein p53

2003
The effect of potent iron chelators on the regulation of p53: examination of the expression, localization and DNA-binding activity of p53 and the transactivation of WAF1.
    Carcinogenesis, 2003, Volume: 24, Issue:10

    Topics: Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dactinomycin; Electrophoretic Mobility Shift Assay; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Iron Chelating Agents; Isoniazid; Protein Synthesis Inhibitors; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53

2003
Regeneration of proximal and distal part of hydra body cut in the middle of gastral cavity and treated with dactinomycine.
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1977, Volume: 91, Issue:2

    Topics: Animals; Dactinomycin; Hydra; Regeneration

1977
Effects of dactinomycine (actinomycine D) on budless hydra and during its budding process.
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1976, Volume: 90, Issue:2

    Topics: Animals; Dactinomycin; Hydra

1976
Effects of ultraviolet light (2535 A) and dactinomycin upon hydra (Pelmatohydra oligactis).
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1981, Volume: 95, Issue:5

    Topics: Animals; Dactinomycin; Hydra; Time Factors; Ultraviolet Rays

1981