dactinomycin has been researched along with indomethacin in 73 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (43.84) | 18.7374 |
| 1990's | 25 (34.25) | 18.2507 |
| 2000's | 9 (12.33) | 29.6817 |
| 2010's | 7 (9.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Burrow, GN; Zusman, DR | 1 |
| Arrigoni-Martelli, E; Binderup, L; Bramm, E | 1 |
| Di Rosa, M; Persico, P | 1 |
| Duval, D; Paing, M; Russo-Marie, F | 1 |
| Bacchetti, P; Giri, SN; Rice, S | 1 |
| Arend, W; Firestein, GS; Tsai, V; Zvaifler, NJ | 1 |
| Bunning, RA; Fawthrop, FW; Oyajobi, BO; Russell, RG | 1 |
| Hayashi, T; Miyabo, S; Nakai, T | 1 |
| Danielová, V; Holubová, J; Sourek, J | 1 |
| Belizario, JE; Dinarello, CA | 1 |
| McKenna, TM | 1 |
| Allison, AC; Schurman, DJ; Smith, RL | 1 |
| Ardaillou, R; Baud, L; Friedlander, G; Perez, J | 1 |
| Bomalaski, JS; Clark, MA; Hirata, F | 1 |
| Covington, M; Newton, RC | 1 |
| Forray, C; Richelson, E | 1 |
| Dayer, JM; Meyer, FA; Yaron, I; Yaron, M | 1 |
| Bartolini, G; Chiricolo, M; Fidan, M; Franceschi, C; Guerrini, F; Minghetti, L; Orlandi, M; Tomasi, V | 1 |
| Gerritsen, ME; Gordon, GG; Southren, AL; Weinstein, BI | 1 |
| Beliard, R; Bocquet, J; Daireaux, M; Jouis, V; Langris, M; Loyau, G; Pujol, JP | 1 |
| Bekemeier, H; Hirschelmann, R | 1 |
| Reilly, MA; Schayer, RW | 1 |
| Houck, JC; Sharma, VK | 1 |
| Gladner, JA; Houck, JC; Patel, YM; Sharma, VK | 1 |
| Borel, JF | 1 |
| Finkelstein, RA; Goth, A; Lexomboon, U | 1 |
| Forbes, IJ; Smith, JL | 1 |
| Bakker, O; Bisschop, A; Meerman, JH; Stavenuiter, JF; van der Heijden, CA; van Wijk, R | 1 |
| Balint, GA; Varro, V | 1 |
| Buchanan, KD; Cantwell, B; Collins, PG; Fennelly, JJ; Fielding, JF; FitzGerald, O | 1 |
| Kuramoto, A; Matsui, I; Morisawa, S; Otani, S; Pegg, AE | 1 |
| Alfonso, M; Coll, J; Segarra, M; Subiza, JL | 1 |
| Amagaya, S; Higuchi, H; Ogihara, Y | 1 |
| Kurihara, A; Ojima, F; Tsurufuji, S | 1 |
| Mikami, T; Miyasaka, K | 1 |
| Bozzini, CE; Giglio, MJ | 1 |
| Goldsmith, LA; Lesiewicz, J; Morrison, DM | 1 |
| Baier, LD; Daphna-Iken, D; DuMaine, J; Morrison, AR; Srivastava, SK; Tetsuka, T | 1 |
| Cunha, FQ; Ferreira, SH; Klein, A | 1 |
| Endo, T; Hayashi, Y; Ogura, T; Ogushi, F; Sone, S; Taketani, Y; Ueda, N; Yamamoto, S | 1 |
| Damoulis, PD; Hauschka, PV | 1 |
| Armstead, WM; Leffler, CW; Mirro, R; Shibata, M | 1 |
| Bjerve, KS; Brekke, OL; Espevik, T | 1 |
| Campbell, IK; Hamilton, JA; Ianches, G | 1 |
| Bry, K; Hallman, M; Lappalainen, U | 1 |
| Castedo, M; Dutilleul, V; Geuskens, M; Kroemer, G; Marchetti, P; Rawadi, G; Roman-Roman, S; Susin, S | 1 |
| Chang, KJ; Im, WB; Kim, JW; Kwon, HB; Lee, J; Schuetz, AW | 1 |
| Heyes, MP; Markey, SP; Noma, A; Saito, K; Seishima, M | 1 |
| Okabe, S; Takahashi, S | 1 |
| Kudo, I; Matsumoto, H; Murakami, M; Naraba, H; Oh-ishi, S; Ueno, A; Yamaki, K | 1 |
| Goto, K; Kasuya, Y; Kimura, S; Masaki, T; Wei, S; Yanagisawa, M | 1 |
| Okabe, S; Takahashi, S; Yamazaki, T | 1 |
| Keles, I; Murray, RD; Woldehiwet, Z | 1 |
| Holland, E; Knox, AJ; Pang, L | 2 |
| Balzarini, J; De Clercq, E; Hatse, S | 1 |
| Ikeda, K; Kanematsu, M; Sato, T; Takai, H; Watanabe, K; Yamada, Y | 1 |
| Deachapunya, C; O'Grady, SM | 1 |
| Levine, L | 2 |
| Valentine, JF | 1 |
| Bradbury, D; Corbett, L; Knox, AJ; Pang, L; Stocks, J | 1 |
| Liu, Z; Sena, J | 1 |
| Berberich, N; Bihari, P; Khandoga, AG; Krombach, F; Lerchenberger, M; Rehberg, M; Reichel, CA; Zahler, S | 1 |
| He, BS; Mi, QY; Pan, YQ; Tai, T; Xie, HG; Zhao, SL | 1 |
1 review(s) available for dactinomycin and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
72 other study(ies) available for dactinomycin and indomethacin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Thyroid-stimulating hormone regulation of ornithine decarboxylase activity in the thyroid.
Topics: Adrenocorticotropic Hormone; Aminophylline; Animals; Bucladesine; Carboxy-Lyases; Dactinomycin; Growth Hormone; Hypophysectomy; Indomethacin; Luteinizing Hormone; Male; Ornithine Decarboxylase; Pituitary Gland; Rats; Thyroid Gland; Thyrotropin; Time Factors | 1975 |
Actinomycin D peritonitis in rats: a tool for the study of early events in inflammation.
Topics: Animals; Cell Movement; Cyclic AMP; Cyclic GMP; Dactinomycin; Disease Models, Animal; Female; Fluprednisolone; Glucuronidase; Indomethacin; L-Lactate Dehydrogenase; Leukocytes; Peritonitis; Prostaglandins E; Prostaglandins F; Rats | 1976 |
Mechanism of inhibition of prostaglandin biosynthesis by hydrocortisone in rat leucocytes.
Topics: Animals; Dactinomycin; Hydrocortisone; Indomethacin; Kinetics; Leukocytes; Male; Phagocytosis; Prostaglandins; Rats | 1979 |
Involvement of glucocorticoid receptors in steroid-induced inhibition of prostaglandin secretion.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Indomethacin; Kidney Medulla; Kinetics; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Receptors, Glucocorticoid; Receptors, Steroid | 1979 |
Characteristic features of actinomycin D-induced paw inflammation of the rat.
Topics: Acid Phosphatase; Animals; Aspirin; Capillary Permeability; Dactinomycin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extremities; Glucuronidase; Histamine; Hydrocortisone; Indomethacin; Inflammation; Male; Rats | 1975 |
Cytokine-induced differentiation of cultured nonadherent macrophages.
Topics: Adult; Cell Adhesion; Cell Separation; Cell Survival; Cells, Cultured; Dactinomycin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Interferon-gamma; Interleukin-2; Macrophages; Methotrexate; Middle Aged; Phagocytosis; Prostaglandins E; Tumor Necrosis Factor-alpha | 1992 |
The effect of transforming growth factor beta on the plasminogen activator activity of normal human osteoblast-like cells and a human osteosarcoma cell line MG-63.
Topics: Bone Remodeling; Cells, Cultured; Cycloheximide; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Humans; Indomethacin; Interleukin-1; Osteoblasts; Osteosarcoma; Recombinant Proteins; Tissue Plasminogen Activator; Transforming Growth Factor beta; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1992 |
Glucocorticoids increase Ca2+ uptake and [3H]dihydropyridine binding in A7r5 vascular smooth muscle cells.
Topics: Amiloride; Analysis of Variance; Androstanols; Animals; Calcium; Calcium Channels; Cell Count; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Dihydropyridines; Electric Conductivity; Glucocorticoids; Indomethacin; Kinetics; Muscle, Smooth, Vascular; Potassium; Proteins; Rats; Receptors, Glucocorticoid; Spironolactone; Water | 1991 |
Some requirements for the secretion of tumour necrosis factor and its cytotoxic activity in vitro.
Topics: Animals; Cell Line, Transformed; Clostridium; Cytotoxicity, Immunologic; Dactinomycin; Escherichia coli; Female; Hot Temperature; Indomethacin; Macrophages; Mice; Mice, Inbred Strains; Polysaccharides, Bacterial; Tumor Necrosis Factor-alpha | 1991 |
Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle.
Topics: Animals; Cell Cycle; Cholera Toxin; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Fibrosarcoma; G1 Phase; Humans; Indomethacin; Interleukin-1; Interleukin-6; Mice; Premedication; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Prolonged exposure of rat aorta to low levels of endotoxin in vitro results in impaired contractility. Association with vascular cytokine release.
Topics: Animals; Aorta; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Endothelium, Vascular; Endotoxins; In Vitro Techniques; Indomethacin; Interleukin-1; Male; Microscopy, Electron, Scanning; Norepinephrine; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha; Vasoconstriction | 1990 |
Induction of articular cartilage degradation by recombinant interleukin 1 alpha and 1 beta.
Topics: Animals; Cartilage, Articular; Cattle; Chromatography, Gel; Cycloheximide; Dactinomycin; Glycosaminoglycans; Indomethacin; Interleukin-1; Organ Culture Techniques; Papain; Proteoglycans; Recombinant Proteins | 1989 |
Tumor necrosis factor stimulates prostaglandin production and cyclic AMP levels in rat cultured mesangial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprost; Dinoprostone; Glomerular Mesangium; Indomethacin; Kidney Cortex; Kinetics; Prostaglandins; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1988 |
Aspirin inhibits phospholipase C.
Topics: Annexins; Aspirin; Cycloheximide; Dactinomycin; Glycoproteins; Humans; Indomethacin; Salicylates; Type C Phospholipases | 1986 |
The activation of human fibroblast prostaglandin E production by interleukin 1.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Line; Cycloheximide; Dactinomycin; Ethers; Fibroblasts; Humans; Indomethacin; Interleukin-1; Ionomycin; Prostaglandins E; Receptors, Immunologic; Receptors, Interleukin-1; Tetradecanoylphorbol Acetate; Time Factors; Trypsin | 1987 |
Glucocorticoids potentiate the prostaglandin E1-mediated cyclic AMP formation by a cultured murine neuroblastoma clone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Corticosterone; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Drug Synergism; Glucocorticoids; Indomethacin; Kinetics; Mice; Neuroblastoma; Prostaglandins E | 1985 |
Human recombinant interleukin-1 beta stimulates glycosaminoglycan production in human synovial fibroblast cultures.
Topics: Cells, Cultured; Cycloheximide; Dactinomycin; Fibroblasts; Glycosaminoglycans; Humans; Hydrocortisone; Indomethacin; Interleukin-1; Microbial Collagenase; Prostaglandins E; Recombinant Proteins; Synovial Membrane | 1987 |
Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system.
Topics: ABO Blood-Group System; Animals; Aspirin; Blood; Cattle; Dactinomycin; Dinoprostone; Enzyme Induction; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Monocytes; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Thromboxane A2; Thromboxane B2 | 1986 |
Prostaglandin synthesis and release from cultured human trabecular-meshwork cells and scleral fibroblasts.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Fibroblasts; Humans; Indomethacin; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins E; Prostaglandins H; Sclera; Trabecular Meshwork | 1986 |
The role of phospholipase activation in cell killing.
Topics: Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Dexamethasone; HeLa Cells; Humans; Indomethacin; Interleukin-1; Kinetics; L Cells; Lymphotoxin-alpha; Phospholipases; Temperature; Tumor Necrosis Factor-alpha | 1987 |
Mononuclear cell-mediated modulation of synovial cell metabolism. II. Increased hyaluronic acid synthesis by a monocyte cell factor (MCF).
Topics: Aged; Cells, Cultured; Dactinomycin; Female; Glucosamine; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Hyaluronic Acid; Indomethacin; Male; Membrane Proteins; Middle Aged; Molecular Weight; Monokines; Proteins; Synovial Membrane; Transferases; Xenopus Proteins | 1985 |
[Inhibition of the incorporation of 14C-leucine into lymphocytes from peritoneal exudate of the rat by cytostatics, antiphlogistics and selenophenones].
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Ascitic Fluid; Azathioprine; Blood Proteins; Carbon Isotopes; Cyclophosphamide; Dactinomycin; Indomethacin; Leucine; Lymphocytes; Male; Phenylbutazone; Rats; Selenium; Sodium Salicylate | 1970 |
Suppression of inflammation and histidine decarboxylase by protein synthesis inhibitors.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Carrageenan; Cycloheximide; Dactinomycin; Endotoxins; Female; Hydrocortisone; Indomethacin; Inflammation; Mice; Polymyxins; Protein Biosynthesis; Proteins; Puromycin; Pyrroles; Rats; Turpentine | 1968 |
Induction of collagenolytic and proteolytic activities in rat and human fibroblasts by anti-inflammatory drugs.
Topics: Animals; Collagen; Cycloheximide; Dactinomycin; Diploidy; Enzyme Induction; Fibroblasts; Humans; Hydrocortisone; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; L Cells; Microbial Collagenase; Oxyphenbutazone; Peptide Hydrolases; Rats; Stimulation, Chemical | 1968 |
Induction of collagenolytic and proteolytic activities by anti-inflammatory drugs in the skin and fibroblast.
Topics: Animals; Collagen; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Enzyme Induction; Fibroblasts; Glucuronidase; Hydrocortisone; Indomethacin; Male; Microbial Collagenase; Oxyphenbutazone; Peptide Hydrolases; Phenytoin; Puromycin; Rats; RNA; Skin; Stimulation, Chemical | 1968 |
Effect of some drugs on the chemotaxis of rabbit neutrophils in vitro.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chemotaxis; Chloroquine; Cyclic AMP; Cytochalasin B; Dactinomycin; Demecolcine; Dexamethasone; Glucocorticoids; Glucose; Hydrocortisone; Indoleacetic Acids; Indomethacin; Lectins; Mitogens; Neutrophils; Pentetic Acid; Phenylbutazone; Rabbits; Salicylates; Trypsin; Vincristine | 1973 |
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone | 1971 |
Use of human lymphocytes in studies of drug action.
Topics: Azathioprine; Benzoates; Chlorambucil; Chloramphenicol; Cyclophosphamide; Dactinomycin; Hydrocortisone; Indomethacin; Lectins; Lymphocytes; Mercaptopurine; Protein Biosynthesis; Puromycin; Salicylates | 1967 |
Induction of ornithine decarboxylase and augmentation of tyrosine aminotransferase activity by N-hydroxy-2-acetylaminofluorene and 2-acetylaminofluorene in rat liver. Influence of sex, retinylacetate, indomethacin, and pentachlorophenol.
Topics: 2-Acetylaminofluorene; Animals; Bucladesine; Cycloheximide; Dactinomycin; Diterpenes; Dose-Response Relationship, Drug; Enzyme Induction; Hydroxyacetylaminofluorene; Indomethacin; Liver; Male; Ornithine Decarboxylase; Pentachlorophenol; Rats; Rats, Inbred Strains; Retinyl Esters; Sex Factors; Tyrosine Transaminase; Vitamin A | 1984 |
Actinomycin inhibits gastric mucosal protection by prostacyclin in rats.
Topics: Animals; Dactinomycin; Epoprostenol; Female; Gastric Mucosa; Indomethacin; Peptic Ulcer; Prostaglandin Antagonists; Rats; Restraint, Physical | 1981 |
Metastatic pancreatic vipoma: a case report of clinical response following treatment with corticosteroids and actinomycin D.
Topics: Adenoma, Islet Cell; Dactinomycin; Female; Humans; Indomethacin; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Prednisolone; Vasoactive Intestinal Peptide; Vipoma | 1982 |
Induction of spermidine N1-acetyltransferase by sodium n-butyrate and phytohemagglutinin in bovine lymphocytes.
Topics: Acetyltransferases; Animals; Butyrates; Butyric Acid; Cattle; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; In Vitro Techniques; Indomethacin; Lymphocytes; Phytohemagglutinins; Substrate Specificity; Time Factors | 1983 |
[Stimulation of cell division by Ehrlich carcinoma cell surface antibodies].
Topics: Animals; Antibodies, Neoplasm; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Membrane; Cell Nucleus; Colchicine; Cycloheximide; Cytochalasin B; Dactinomycin; DNA, Neoplasm; Female; Immune Sera; Indomethacin; Interphase; Mice; Mitomycin; Mitomycins; Neoplasm Proteins; Rabbits; RNA, Neoplasm | 1984 |
Blockade by anti-glucocorticoids, actinomycin D and cycloheximide of the anti-inflammatory action of some Kampohozai (Chinese traditional medicines) against serotonin.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cycloheximide; Dactinomycin; Dexamethasone; Drugs, Chinese Herbal; Glucocorticoids; Indomethacin; Inflammation; Magnoliopsida; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Methyltestosterone; Mice; Phenylbutazone; Phytotherapy; Progesterone; Serotonin; Serotonin Antagonists; Time Factors | 1984 |
Mechanisms of anti-inflammatory action of dexamethasone: blockade by hydrocortisone mesylate and actinomycin D of the inhibitory effect of dexamethasone on leukocyte infiltration in inflammatory sites.
Topics: Androstenedione; Animals; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Hydrocortisone; Indomethacin; Inflammation; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Inbred Strains | 1984 |
Comparison of the anti-inflammatory effects of dexamethasone, indomethacin and BW755C on carrageenin-induced pleurisy in rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Carrageenan; Dactinomycin; Dexamethasone; Disease Models, Animal; Indomethacin; Male; Pleurisy; Pyrazoles; Rats; Rats, Inbred Strains | 1982 |
Effect of indomethacin on red cell volume, iron kinetics and red cell survival in mice.
Topics: Animals; Dactinomycin; Dose-Response Relationship, Drug; Erythrocyte Aging; Erythrocyte Volume; Erythrocytes; Erythropoiesis; Female; Indomethacin; Iron; Kinetics; Mice; Time Factors | 1982 |
Ornithine decarboxylase in rat skin: 2. Differential response to hair plucking and a tumor promoter.
Topics: Animals; Carboxy-Lyases; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Epidermis; Hair Removal; Half-Life; Indomethacin; Male; Ornithine Decarboxylase; Physical Stimulation; Rats; Skin; Tetradecanoylphorbol Acetate | 1980 |
Cross-talk between cyclooxygenase and nitric oxide pathways: prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1.
Topics: Amino Acid Oxidoreductases; Animals; Base Sequence; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Dinoprostone; DNA Primers; DNA Probes; Enzyme Induction; Gene Expression; Glomerular Mesangium; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Indomethacin; Interleukin-1; Kinetics; Male; Models, Biological; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1994 |
The role of lymphocytes in the neutrophil migration induced by ovalbumin in immunized rats.
Topics: Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Concanavalin A; Cytokines; Dactinomycin; Dexamethasone; Hot Temperature; Indomethacin; Lymphocyte Transfusion; Lymphocytes; Male; Neutrophils; Ovalbumin; Phytohemagglutinins; Rats; Rats, Wistar | 1995 |
Induction of cyclooxygenase-2 is responsible for interleukin-1 beta-dependent prostaglandin E2 synthesis by human lung fibroblasts.
Topics: Base Sequence; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; DNA Primers; Enzyme Induction; Fibroblasts; Gene Expression; Humans; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-4; Lung; Molecular Sequence Data; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides | 1995 |
Cytokines induce nitric oxide production in mouse osteoblasts.
Topics: 3T3 Cells; Animals; Arginine; Cell Line; Cell Survival; Citrulline; Cycloheximide; Cytokines; Dactinomycin; Dexamethasone; Egtazic Acid; Escherichia coli; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Osteoblasts; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Actinomycin D blocks interleukin-1 alpha-induced pial arteriolar dilation and increased prostanoid production in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Blood Gas Analysis; Dactinomycin; Female; Histamine; Indomethacin; Interleukin-1; Male; Prostaglandins; Recombinant Proteins; Swine; Vasodilation | 1994 |
Butylated hydroxyanisole inhibits tumor necrosis factor-induced cytotoxicity and arachidonic acid release.
Topics: Animals; Arachidonic Acid; Butylated Hydroxyanisole; Cell Line; Cell Survival; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Fibrosarcoma; Indomethacin; Kinetics; Mice; Recombinant Proteins; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vitamin E | 1994 |
Production of macrophage colony-stimulating factor (M-CSF) by human articular cartilage and chondrocytes. Modulation by interleukin-1 and tumor necrosis factor alpha.
Topics: Cartilage, Articular; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Humans; Indomethacin; Interleukin-1; Macrophage Colony-Stimulating Factor; Organ Culture Techniques; Tumor Necrosis Factor-alpha | 1993 |
Interleukin-1 binding and prostaglandin E2 synthesis by amnion cells in culture: regulation by tumor necrosis factor-alpha, transforming growth factor-beta, and interleukin-1 receptor antagonist.
Topics: Amnion; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Indomethacin; Interleukin-1; Pregnancy; Receptors, Interleukin-1; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation | 1993 |
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
Topics: Acquired Immunodeficiency Syndrome; Apoptosis; Biological Factors; Cell Differentiation; Cyclooxygenase Inhibitors; Dactinomycin; HL-60 Cells; Hot Temperature; Humans; Indomethacin; Interleukin-1; Interleukin-6; Lymphoma, Large B-Cell, Diffuse; Macrophages; Molecular Weight; Monocytes; Mycoplasma fermentans; Mycoplasma Infections; Phagocytosis; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Prostaglandin production and ovulation during exposure of amphibian ovarian follicles to gonadotropin or phorbol ester in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprost; Enzyme Inhibitors; Female; Gonadotropins; Indomethacin; Ovulation; Phorbol Esters; Protein Synthesis Inhibitors; Radioimmunoassay; Ranidae | 1995 |
Cytokine and drug modulation of kynurenine pathway metabolism by blood mononuclear cells.
Topics: Analysis of Variance; Carbon Isotopes; Cell Line; Dactinomycin; Dexamethasone; Humans; Hydrolases; Indomethacin; Interferon-gamma; Kinetics; Kynurenine; Kynurenine 3-Monooxygenase; Leukemia, Monocytic, Acute; Lipopolysaccharides; Macrophages; Mixed Function Oxygenases; Monocytes; Quinolinic Acid; Radioisotope Dilution Technique; Regression Analysis; Salmonella; Tritium; Tryptophan Oxygenase | 1996 |
The cytoprotective effect of leminoprazole on indomethacin-induced damage to rabbit gastric mucosal cells.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Benzimidazoles; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Gastric Mucosa; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Rabbits | 1996 |
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages.
Topics: Animals; Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprostone; Enzyme Induction; Indomethacin; Intramolecular Oxidoreductases; Isoenzymes; Isomerases; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Nitrobenzenes; Prostaglandin D2; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2 | 1997 |
Studies on endothelium-dependent vasorelaxation by hydralazine in porcine coronary artery.
Topics: Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dactinomycin; Endothelium; Hemoglobins; Hydralazine; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Protein Synthesis Inhibitors; Swine; Vasodilator Agents | 1997 |
Leminoprazole protects cultured gastric mucosal cells against damage caused by ethanol, indometacin and taurocholate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Benzimidazoles; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cholagogues and Choleretics; Cycloheximide; Dactinomycin; Dinoprostone; Ethanol; Gastric Mucosa; Indomethacin; Male; Omeprazole; Oxytocics; Protein Synthesis Inhibitors; Rabbits; Solvents; Taurocholic Acid | 1997 |
Replication of bovine respiratory syncytial virus in bovine and ovine peripheral blood lymphocytes and monocytes and monocytic cell lines.
Topics: Animals; Bone Marrow Cells; Cattle; Cell Line; Cells, Cultured; Dactinomycin; Humans; Indomethacin; Interleukin-2; Kinetics; Leukocytes, Mononuclear; Liver; Lymphocytes; Macrophages, Alveolar; Monocytes; Organ Specificity; Recombinant Proteins; Respiratory Syncytial Virus, Bovine; Sheep; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virus Replication | 1998 |
Impaired cAMP production in human airway smooth muscle cells by bradykinin: role of cyclooxygenase products.
Topics: Adult; Bradykinin; Calcimycin; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Female; Humans; Indomethacin; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Middle Aged; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptor, Bradykinin B2; Receptors, Bradykinin; Sulfonamides; Trachea | 1998 |
Enhanced 9-(2-phosphonylmethoxyethyl)adenine secretion by a specific, indomethacin-sensitive efflux pump in a mutant 9-(2-phosphonylmethoxyethyl)adenine-resistant human erythroleukemia K562 cell line.
Topics: Adenine; Adenine Nucleotides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cycloheximide; Dactinomycin; Drug Resistance, Neoplasm; Extracellular Space; Flow Cytometry; Humans; Immunoblotting; Indomethacin; K562 Cells; Mice; Multidrug Resistance-Associated Proteins; Mutation; Organophosphonates; Prodrugs; Protein Synthesis Inhibitors; Sensitivity and Specificity; Temperature; Zidovudine | 1998 |
Role of cyclo-oxygenase-2 induction in interleukin-1beta induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline.
Topics: Adrenergic beta-Agonists; Adult; Arachidonic Acid; Cell Survival; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Female; Glucocorticoids; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Middle Aged; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Sulfonamides; Trachea; Tumor Necrosis Factor-alpha | 1998 |
Prostaglandin E2 induces expression of receptor activator of nuclear factor-kappa B ligand/osteoprotegrin ligand on pre-B cells: implications for accelerated osteoclastogenesis in estrogen deficiency.
Topics: Animals; B-Lymphocytes; Bone Marrow Cells; Carrier Proteins; Cell Adhesion; Cell Line; Cycloheximide; Dactinomycin; Dinoprostone; Estrogens; Female; Gene Expression Regulation; Indomethacin; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Models, Biological; Osteoclasts; Osteogenesis; Ovariectomy; Protein Biosynthesis; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Stromal Cells; Transcription, Genetic | 2000 |
Epidermal growth factor regulates the transition from basal sodium absorption to anion secretion in cultured endometrial epithelial cells.
Topics: Amiloride; Animals; Biological Transport; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cyclooxygenase Inhibitors; Dactinomycin; Endometrium; Epidermal Growth Factor; Epithelial Cells; Female; Indomethacin; Insulin; Ionomycin; Kinetics; Nitrobenzoates; Prostaglandins; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Transforming Growth Factor alpha | 2001 |
Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cell Line; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Drug Interactions; Glucocorticoids; Indomethacin; Isoenzymes; Liver; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Pyrazoles; Rats; Sulfonamides | 2001 |
Mesalamine induces manganese superoxide dismutase in rat intestinal epithelial cell lines and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Enzyme Induction; Free Radical Scavengers; Humans; Immunoblotting; Indoles; Indomethacin; Intestinal Mucosa; Lipopolysaccharides; Lipoxygenase Inhibitors; Mesalamine; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Rats; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2001 |
Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors.
Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Kinetics; Liver; Prostaglandin D2; Prostaglandins A; Pyrazoles; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 2001 |
Cytokines upregulate vascular endothelial growth factor secretion by human airway smooth muscle cells: Role of endogenous prostanoids.
Topics: Blotting, Western; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Indomethacin; Interleukin-1; Kinetics; Luciferases; Membrane Proteins; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Trachea; Transforming Growth Factor beta; Up-Regulation; Vascular Endothelial Growth Factor A | 2005 |
Expression of cyclooxygenase genes and production of prostaglandins during ovulation in the ovarian follicles of Xenopus laevis.
Topics: Animals; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprost; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Gonadotropins; Immunoenzyme Techniques; Indomethacin; Isoenzymes; Ovarian Follicle; Ovulation; Progesterone; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Xenopus laevis; Xenopus Proteins | 2008 |
Ccl2 and Ccl3 mediate neutrophil recruitment via induction of protein synthesis and generation of lipid mediators.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Benzoquinones; Cells, Cultured; Chemokine CCL2; Chemokine CCL3; Chemotaxis, Leukocyte; Dactinomycin; Disease Models, Animal; Indoles; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Protein Biosynthesis; Random Allocation; Sensitivity and Specificity | 2009 |
The molecular mechanism underlying the induction of hepatic MRP3 expression and function by omeprazole.
Topics: Biological Transport; Dactinomycin; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Indomethacin; Liver; Multidrug Resistance-Associated Proteins; Omeprazole; RNA, Small Interfering; Up-Regulation | 2015 |