dactinomycin and folic acid

dactinomycin has been researched along with folic acid in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199024 (64.86)18.7374
1990's3 (8.11)18.2507
2000's1 (2.70)29.6817
2010's9 (24.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Clements, GB1
Roth, JJ; Roth, JS1
Didenko, AV1
Grzelakowska-Sztabert, B1
Da Costa, M; Rothenberg, SP1
Bonney, RJ; Maley, F1
Miyachi, H; Ohnuma, T; Sekiguchi, S; Takemura, Y1
Chacko, KV; Hise, MK1
Flam, F; Lundström, V1
Meerson, FZ; Rozanova, LS1
Brade, W; Herken, H; Kolbe, H; Voss, P1
Herman, RH; Rosensweig, NS; Stifel, FB1
Catovsky, D; Das, KC; Hoffbrand, V; Tripp, E1
Greene, HL; Hagler, L; Herman, RH; Lufkin, EG; Stifel, FB; Taunton, OD1
Frank, W1
Bezborodov, VA; Bredov, VI; Dergachev, VV; Krylov, OA; Oreshuk, FA1
Hollatz, R; Tempel, K1
Jähde, H; Tempel, K1
Viñuela, E1
Ohara, O; Silber, R1
Bloch, A1
Das, KC; Hoffbrand, AV1
Motycka, K; Pristoupilová, K; Slavík, K; Soucek, J1
Taylor, DM; Threlfall, G1
Bublitz, C; Priest, RE1
Lurain, JR1
BROCKMAN, RW1
Clarke-Pearson, DL; Kirkpatrick, JP; Sampson, JH; Soper, JT; Spillman, M; Wolf, JK1
Chiang, EP; Wang, YC1
Berkowitz, RS; Bernstein, MR; Goldstein, DP; Horowitz, NS; Maestá, I; Ramírez, LA1
Kovalev, VI; Vekshin, NL1
Finnell, RH; Toriyama, M; Wallingford, JB1
Li, J; Li, S; Lu, X; Wang, J; Xu, C; Yu, H1

Reviews

5 review(s) available for dactinomycin and folic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Selection of biochemically variant, in some cases mutant, mammalian cells in culture.
    Advances in cancer research, 1975, Volume: 21

    Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Base Sequence; Carbohydrates; Cell Fusion; Cell Separation; Cells, Cultured; Cricetinae; Dactinomycin; Deoxycytidine; Drug Resistance; Epitopes; Folic Acid; Genes; Genes, Regulator; Guinea Pigs; Hot Temperature; Humans; Immunoglobulins; Mice; Mutation; Nucleosides; Phenotype; Purines; Puromycin; Rabbits; Rats; Temperature; Thymidine; Time Factors; Uracil; Uridine

1975
Management of high-risk gestational trophoblastic disease.
    The Journal of reproductive medicine, 1998, Volume: 43, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cyclophosphamide; Dactinomycin; Etoposide; Female; Folic Acid; Humans; Liver Neoplasms; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine

1998
MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.
    Advances in cancer research, 1963, Volume: 7

    Topics: Alkylating Agents; Antineoplastic Agents; Azaserine; Dactinomycin; DNA; Drug Resistance; Drug Resistance, Microbial; Drug Tolerance; Folic Acid; Humans; Leucine; Metabolism; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; RNA; Steroids; Tissue Culture Techniques

1963
The efficacy and safety of first-line single-agent chemotherapy regimens in low-risk gestational trophoblastic neoplasia: A network meta-analysis.
    Gynecologic oncology, 2018, Volume: 148, Issue:2

    Topics: Antineoplastic Agents; Dactinomycin; Drug Administration Schedule; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Infusions, Intravenous; Injections, Intramuscular; Methotrexate; Nausea; Pregnancy; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vomiting

2018

Other Studies

32 other study(ies) available for dactinomycin and folic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thymidylate synthetase activity in the Novikoff hepatoma.
    Cancer research, 1976, Volume: 36, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Folic Acid; Liver Neoplasms; Male; Methotrexate; Methyltransferases; Neoplasms, Experimental; Puromycin; Rats; Tetrahydrofolates; Thymidylate Synthase

1976
[Effect of inhibitors and stimulators of protein metabolism on the resting potentials of Retzius neurons in the leech].
    Doklady Akademii nauk SSSR, 1979, Volume: 246, Issue:4

    Topics: Animals; Dactinomycin; Flavoproteins; Folic Acid; In Vitro Techniques; Leeches; Membrane Potentials; Neurons; RNA; Stimulation, Chemical

1979
Uptake of folate and its analogue-amethopterin by mouse L-cells.
    Acta biochimica Polonica, 1976, Volume: 23, Issue:4

    Topics: Animals; Cells, Cultured; Chloromercuribenzoates; Cycloheximide; Dactinomycin; Folic Acid; Kinetics; L Cells; Methionine; Methotrexate; Mice; Vitamin B 12

1976
Studies with the folate binding protein in chronic granulocytic leukaemia cells. I. Synthesis and release of binder by cells in short-term culture.
    British journal of haematology, 1976, Volume: 34, Issue:4

    Topics: Carrier Proteins; Chromatography, Agarose; Dactinomycin; Folic Acid; Humans; Leukemia, Myeloid; Protein Binding; Time Factors

1976
Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver.
    Cancer research, 1975, Volume: 35, Issue:8

    Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Liver; Liver Regeneration; Methotrexate; Methyltransferases; Protein Biosynthesis; Puromycin; Rats; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase

1975
A human leukemia cell line made resistant to two folate analogues, trimetrexate and N10-propargyl-5,8-dideazafolic acid (CB3717).
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line; Cisplatin; Cross Reactions; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Folic Acid; Humans; Leucovorin; Membrane Glycoproteins; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinazolines; RNA, Messenger; Thymidylate Synthase; Trimetrexate; Vincristine

1991
Regulation of ornithine decarboxylase in rat kidney.
    Nephron, 1990, Volume: 55, Issue:4

    Topics: Animals; Carcinogens; Cycloheximide; Dactinomycin; Diterpenes; Folic Acid; Homeostasis; Kidney; Liver; Male; Nephrectomy; Ornithine Decarboxylase; Protein Kinase C; Rats; Rats, Inbred Strains; Reference Values; Terpenes; Tetradecanoylphorbol Acetate

1990
Twenty years' experience of treating gestational trophoblastic neoplasia in Sweden.
    Acta obstetricia et gynecologica Scandinavica, 1989, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Combined Modality Therapy; Dactinomycin; Female; Folic Acid; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Prognosis; Sweden; Trophoblastic Neoplasms; Uterine Neoplasms

1989
[The effect of actinomycin 2703 and a complex stimulating nucleic acid synthesis on the development of fatigue and training state].
    Doklady Akademii nauk SSSR, 1966, Jan-11, Volume: 166, Issue:2

    Topics: Animals; Behavior, Animal; Dactinomycin; Fatigue; Folic Acid; Mice; Nucleic Acids; Orotic Acid; Vitamin B 12

1966
Induction of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in the regenerating kidney after lesions by drugs.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:4

    Topics: Animals; Carbon Isotopes; Cycloheximide; Dactinomycin; Depression, Chemical; Enzyme Induction; Folic Acid; Glucose; Glucosephosphate Dehydrogenase; Ischemia; Kidney; Male; Pentosephosphates; Phosphogluconate Dehydrogenase; Pyrimidines; Rats; Regeneration; Ribose; Stimulation, Chemical; Styrenes

1970
Dietary regulation of glycolytic enzymes. XI. Effect of inhibitors of protein synthesis on the adaptation of certain jejunal glycolytic and folate-metabolizing enzymes to diet and sex steroids.
    Biochimica et biophysica acta, 1971, Jun-22, Volume: 237, Issue:3

    Topics: Aldehyde-Lyases; Animals; Caseins; Dactinomycin; Dietary Carbohydrates; Dietary Proteins; Enzyme Induction; Estradiol; Ethionine; Fasting; Female; Folic Acid; Fructose; Fructosephosphates; Glycolysis; Jejunum; Male; Metabolism; NAD; Oxidoreductases; Pyruvate Kinase; Rats; RNA; Serine; Testosterone; Time Factors; Transferases

1971
Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis.
    British journal of haematology, 1973, Volume: 25, Issue:4

    Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Culture Techniques; Cyclic AMP; Dactinomycin; Deoxyuridine; DNA; Folic Acid; Humans; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; Mitosis; Phosphodiesterase Inhibitors; Puromycin; RNA; Theophylline; Thymidine; Tritium

1973
Hormonal regulation of hepatic and jejunal formiminotransferase activity in man and rat.
    Biochimica et biophysica acta, 1974, Jul-04, Volume: 354, Issue:2

    Topics: Animals; Child; Child, Preschool; Cyclic AMP; Dactinomycin; Epinephrine; Folic Acid; Formates; Glucagon; Glutamates; Humans; Imines; Insulin; Intestinal Mucosa; Jejunum; Liver; Male; Organ Specificity; Puromycin; Rats; Species Specificity; Tetrahydrofolates; Time Factors; Transferases; Tritium

1974
[On the influence of RNA and protein synthesis in ascites cells].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1967, Volume: 22, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Arginase; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Dactinomycin; Folic Acid; Glycerolphosphate Dehydrogenase; Histones; In Vitro Techniques; L-Lactate Dehydrogenase; Leucine; Neoplasm Proteins; Protamines; Rats; Ribonucleases; RNA, Neoplasm; Tritium; Uridine

1967
[Relation of an inhibitor of DNA-dependent RNA synthesis and stimulators of nucleic acid and protein metabolism to the electrical activity of skin mechanoreceptors].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1974, Volume: 60, Issue:6

    Topics: Animals; Dactinomycin; Depression, Chemical; DNA; Folic Acid; Male; Mechanoreceptors; Neural Conduction; Orotic Acid; Proteins; Rats; RNA; Skin; Stimulation, Chemical; Vitamin B 12

1974
[Induction effects in the mouse under the influence of polyanions].
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 210, Issue:1

    Topics: Aniline Compounds; Animals; Carbon Radioisotopes; Dactinomycin; DNA; Enzyme Induction; Female; Folic Acid; In Vitro Techniques; Kidney; Mice; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Orotic Acid; Phenobarbital; Phenylalanine; Polysaccharides; Protein Biosynthesis; RNA; Sulfuric Acids

1974
[Regneration of mouse kidney after damage by folic acid, whole body x-ray irradiation, 2,4,6-triethyl enimino-1,3,5-triazine, and polyanions].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:12

    Topics: Animals; Dactinomycin; DNA; Female; Folic Acid; Kidney; Mice; Polysaccharides; Polyvinyls; Prednisolone; Protein Biosynthesis; Proteins; Puromycin; Radiation; Radiation Effects; Regeneration; Triazines

1972
Virus-specific proteins in Escherichia coli infected with the RNA bacteriophage MS2.
    Bulletin de la Societe de chimie biologique, 1968, Volume: 50, Issue:12

    Topics: Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Dactinomycin; Detergents; Electrophoresis; Escherichia coli; Eukaryota; Folic Acid; Genetic Code; Histidine; Kinetics; Leucine; Methionine; Molecular Weight; Peptides; Protoplasts; RNA, Viral; Tritium; Uracil; Viral Proteins; Virus Replication

1968
Studies on the regulation of one-carbon metabolism. The effects of folate concentration in the growth medium on the activity of three folate-dependent enzymes in Lactobacillus casei.
    The Journal of biological chemistry, 1969, Apr-25, Volume: 244, Issue:8

    Topics: Chloramphenicol; Culture Media; Dactinomycin; Depression, Chemical; DNA Nucleotidyltransferases; Enzyme Repression; Folic Acid; Folic Acid Antagonists; Glucosephosphate Dehydrogenase; Hexokinase; Lactobacillus; Ligases; Oxidoreductases; Stimulation, Chemical; Temperature; Tetrahydrofolate Dehydrogenase; Thymine

1969
Induction of the dihydrofolate reductase of Streptococcus faecium var. Durans by folic acid and by some of its derivatives.
    Biochimica et biophysica acta, 1970, Feb-24, Volume: 201, Issue:2

    Topics: Cell-Free System; Chemical Phenomena; Chemistry; Chloramphenicol; Culture Media; Dactinomycin; Enzyme Induction; Folic Acid; Leucovorin; Methotrexate; Purines; Streptococcus; Tetrahydrofolate Dehydrogenase; Thymine; Time Factors

1970
Studies of folate uptake by phytohaemagglutinin-stimulated lymphocytes.
    British journal of haematology, 1970, Volume: 19, Issue:2

    Topics: Adult; Anemia, Macrocytic; Anemia, Pernicious; Autoradiography; Biological Transport, Active; Carbon Isotopes; Cell Division; Culture Techniques; Dactinomycin; Folic Acid; Humans; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Methotrexate; Phenytoin; RNA; Stimulation, Chemical; Temperature; Tritium

1970
The treatment of experimental mouse hemoblastosis. VI.
    Neoplasma, 1968, Volume: 15, Issue:1

    Topics: Aminopterin; Animals; Bromine; Coenzymes; Dactinomycin; Folic Acid; Leukemia, Experimental; Liver; Spleen

1968
Modification of folic acid-induced changes in renal nucleic acid and protein synthesis by actinomycin D and cycloheximide.
    European journal of biochemistry, 1969, Volume: 8, Issue:4

    Topics: Animals; Carbon Isotopes; Cycloheximide; Dactinomycin; Depression, Chemical; DNA Replication; Folic Acid; Kidney; Lysine; Male; Protein Biosynthesis; Rats; RNA; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Uridine

1969
The influence of ascorbic acid and tetrahydropteridine on the synthesis of hydroxyproline by cultured cells.
    Laboratory investigation; a journal of technical methods and pathology, 1967, Volume: 17, Issue:4

    Topics: Animals; Ascorbic Acid; Carbon Isotopes; Culture Media; Culture Techniques; Dactinomycin; Folic Acid; Hydroxyproline; Mercaptoethanol; Mice; Mitosis; Pteridines; RNA; RNA, Messenger

1967
High-risk gestational trophoblastic neoplasia with brain metastases: individualized multidisciplinary therapy in the management of four patients.
    Gynecologic oncology, 2007, Volume: 104, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Cisplatin; Craniotomy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Methotrexate; Neoplasm Staging; Pregnancy; Radiosurgery; Risk Factors; Vincristine

2007
Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo.
    Molecular medicine (Cambridge, Mass.), 2012, May-09, Volume: 18

    Topics: Animals; Antirheumatic Agents; Dactinomycin; Dexamethasone; Enzyme Inhibitors; Folic Acid; Gene Expression Regulation; Hep G2 Cells; Humans; Male; Methionine; Methionine Adenosyltransferase; Methotrexate; Mice; Mice, Inbred C57BL; RNA, Messenger; S-Adenosylmethionine

2012
Relationship between race and clinical characteristics, extent of disease, and response to chemotherapy in patients with low-risk gestational trophoblastic neoplasia.
    Gynecologic oncology, 2015, Volume: 138, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asian; Black or African American; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Risk Factors; White People; Young Adult

2015
Nucleotide carriers for anti-tumour actinomycin antibiotics.
    Journal of biochemistry, 2016, Volume: 159, Issue:1

    Topics: Adenine; Antibiotics, Antineoplastic; Caffeine; Dactinomycin; DNA; Drug Carriers; Fluorescent Dyes; Folic Acid; Guanine; Nucleotides; Thymine

2016
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017, Volume: 31, Issue:8

    Topics: Animals; Cilia; Dactinomycin; Embryo, Mammalian; Embryo, Nonmammalian; Embryonic Development; Folic Acid; Gene Expression Regulation, Developmental; Hedgehog Proteins; HEK293 Cells; Humans; Methylation; Mice; Neural Tube; Neural Tube Defects; Plasmids; Septins; Signal Transduction; Xenopus

2017