dactinomycin has been researched along with flutamide in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cantabrana, B; Gutierrez, M; Hidalgo, A; Sánchez Aparicio, JA | 1 |
| Estensen, RD; Ludowese, C; Sinha, AA; Wilson, MJ | 1 |
| Man, RY; Quan, A; Teoh, H | 1 |
| Leung, SW; Man, RY; Quan, A; Teoh, H | 1 |
| Hareramadas, B; Rai, U | 1 |
| González, L; Navarrete, E; Perusquía, M; Villalón, CM | 1 |
| Guarino, G; Spampinato, S | 1 |
| Chavalmane, AK; Desai, KV; Kondaiah, P; Limaye, AM | 1 |
| Díaz, M; Gómez, T; González-Montelongo, MC; Marín, R; Marrero-Alonso, J | 1 |
| Centurión, D; Cobos-Puc, LE; González-Hernández, A; Maassenvandenbrink, A; Muñoz-Islas, E; Ramírez-Rosas, MB; Sánchez-López, A; Villalón, CM | 1 |
| Avellar, MC; Callera, GE; Camargo, LL; Carvalho, MH; Chignalia, AZ; Fortes, ZB; Laurindo, FR; Lopes, LR; Montezano, AC; Schuldt, EZ; Tostes, RC; Touyz, RM | 1 |
1 review(s) available for dactinomycin and flutamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for dactinomycin and flutamide
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Effects of androgens on isolated rat uterus.
Topics: Animals; Cycloheximide; Cyproterone Acetate; Dactinomycin; Dihydrotestosterone; Drug Interactions; Female; Flutamide; In Vitro Techniques; Muscle Contraction; Rats; Rats, Wistar; Uterus | 1993 |
Effects of castration on plasminogen activator activities and plasminogen activator inhibitor type 1 in the rat ventral prostate.
Topics: Amiloride; Androgen Antagonists; Animals; Anti-Inflammatory Agents; Dactinomycin; Diuretics; Electrophoresis, Polyacrylamide Gel; Flutamide; Gene Expression Regulation; Hydrocortisone; Immunoblotting; Male; Orchiectomy; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Prostate; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Testosterone; Tranexamic Acid; Urokinase-Type Plasminogen Activator | 1996 |
Acute impairment of relaxation by low levels of testosterone in porcine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Androgen Receptor Antagonists; Animals; Bradykinin; Calcimycin; Coronary Vessels; Cromakalim; Cycloheximide; Cyproterone; Dactinomycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flutamide; Ionophores; Male; Nitroprusside; Swine; Testosterone; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Differential effects of 17beta-estradiol and testosterone on the contractile responses of porcine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Coronary Vessels; Cycloheximide; Cyproterone; Dactinomycin; Dose-Response Relationship, Drug; Endothelin-1; Estradiol; Estrogen Antagonists; Female; Flutamide; Fulvestrant; In Vitro Techniques; Isotonic Solutions; Male; Potassium Chloride; Receptors, Estrogen; Serotonin; Swine; Tamoxifen; Testosterone; Vasoconstriction | 2000 |
Mechanism of androgen-induced thymic atrophy in the wall lizard, Hemidactylus flaviviridis: an in vitro study.
Topics: Androgen Antagonists; Androgens; Animals; Apoptosis; Caspases; Cell Proliferation; Cycloheximide; Dactinomycin; Dihydrotestosterone; Flutamide; In Vitro Techniques; Lizards; Male; Protein Synthesis Inhibitors; Thymus Gland | 2005 |
The modulatory role of androgens and progestins in the induction of vasorelaxation in human umbilical artery.
Topics: Androgens; Calcium Chloride; Dactinomycin; Dose-Response Relationship, Drug; Flutamide; Humans; Potassium Channels; Progestins; Structure-Activity Relationship; Umbilical Arteries; Vasodilation | 2007 |
Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells.
Topics: Androgen Antagonists; Blotting, Western; Cell Line, Tumor; Dactinomycin; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Nandrolone; Neuroblastoma; Nucleic Acid Synthesis Inhibitors; Plasmids; Promoter Regions, Genetic; Receptors, Opioid, mu; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection | 2008 |
Regulation of mRNAs encoding MMP-9 and MMP-2, and their inhibitors TIMP-1 and TIMP-2 by androgens in the rat ventral prostate.
Topics: Androgens; Animals; Base Sequence; Blotting, Northern; Castration; Dactinomycin; Flutamide; Gelatin; Gene Expression Regulation, Enzymologic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Molecular Sequence Data; Prostate; Protein Binding; Rats; Rats, Wistar; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transcription, Genetic | 2008 |
Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17.
Topics: Amides; Androgens; Animals; Benzophenanthridines; Blotting, Western; Calcium; Colon; Cycloheximide; Dactinomycin; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; In Vitro Techniques; Male; Mice; Models, Biological; Models, Theoretical; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein Kinase C; Pyridines; Receptors, Androgen; rho-Associated Kinases; Signal Transduction; Testosterone | 2010 |
Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.
Topics: 4-Aminopyridine; Adenine; Aminoglutethimide; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Barium Compounds; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chlorides; Cycloheximide; Dactinomycin; Dogs; Enzyme Inhibitors; Flutamide; In Vitro Techniques; Male; Nifedipine; Nucleic Acid Synthesis Inhibitors; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Protein Synthesis Inhibitors; Quinoxalines; Testosterone; Vasodilation; Vasodilator Agents | 2011 |
Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways.
Topics: Androgen Antagonists; Androgens; Animals; Cell Movement; Cells, Cultured; Cycloheximide; Dactinomycin; Flutamide; Immunoblotting; Male; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Testosterone | 2012 |