dactinomycin and eflornithine

dactinomycin has been researched along with eflornithine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199015 (57.69)18.7374
1990's9 (34.62)18.2507
2000's1 (3.85)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fong, WF; Hau, KP; Wong, PC1
Arcot, SS; Gillespie, MN; Haven, CA; Olson, JW1
Carper, SW; Chen, JR; Clay, L; Fuller, DJ; Gerner, EW1
Borghgraef, R; De Smedt, H; Geuns, J; Parys, JB; Van Den Bosch, L1
Welsh, N1
Egyházi, E; Emanuelsson, H; Heby, O; Långström, E; Löwkvist, B; Sjöberg, J1
Wells, MR1
Campbell, RM; Scanes, CG1
Bardocz, S; Hesketh, JE1
Goldstone, AD; Koenig, H; Lu, CY1
Bacchi, CJ; Bitonti, AJ; Garofalo, J; Hannan, JC; McCann, PP; Santana, A1
Gawel-Thompson, KJ; Greene, RM1
Caldarera, CM; Carati, D; Flamigni, F; Rossoni, C; Stefanelli, C1
Greene, RM; Pisano, MM1
Baylin, SB; Casero, RA; Celano, P; Giardiello, FM; Nelkin, BD1
Bjornsson, TD; Dryjski, M; Korner, G; Kuo, BS1
Lawson, DE; Steeves, RM1
Gurpide, E; Holinka, CF1
Cruz, NF; Dienel, GA1
Gerner, EW; Ignatenko, NA1
Cantabrana, B; Hidalgo, A; Revuelta, MP3
Bass, BL; Li, J; Patel, AR; Wang, JY1
Dai, YR; Galston, AW; Kaur-Sawhney, R1

Other Studies

26 other study(ies) available for dactinomycin and eflornithine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Relationship between Ca2+ and L-asparagine in the induction of ornithine decarboxylase in H-35 rat hepatoma cells.
    Biochemistry international, 1992, Volume: 28, Issue:1

    Topics: Animals; Asparagine; Calcium; Cations; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Induction; Half-Life; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Signal Transduction; Tumor Cells, Cultured

1992
Polyamine transport and ornithine decarboxylase activity in hypoxic pulmonary artery smooth muscle cells.
    American journal of respiratory cell and molecular biology, 1992, Volume: 7, Issue:3

    Topics: Animals; Biological Transport; Blotting, Northern; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Eflornithine; Kinetics; Muscle, Smooth, Vascular; Ornithine Decarboxylase; Oxygen; Pulmonary Artery; Spermidine

1992
Polyamine regulation of heat-shock-induced spermidine N1-acetyltransferase activity.
    The Biochemical journal, 1990, May-01, Volume: 267, Issue:3

    Topics: Acetyltransferases; Animals; Biogenic Amines; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; Diamines; Eflornithine; Enzyme Induction; Hot Temperature; Humans; Putrescine; Transcription, Genetic

1990
Regulation of the Na(+)-dependent and the Na(+)-independent polyamine transporters in renal epithelial cells (LLC-PK1).
    Journal of cellular physiology, 1990, Volume: 144, Issue:3

    Topics: Animals; Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Cells, Cultured; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Eflornithine; Epithelial Cells; Epithelium; Kidney; Mitoguazone; Polyamines; Putrescine; Serum Albumin, Bovine; Sodium; Spermidine; Spermine; Swine

1990
A role for polyamines in glucose-stimulated insulin-gene expression.
    The Biochemical journal, 1990, Oct-15, Volume: 271, Issue:2

    Topics: Animals; Cell Nucleus; Culture Techniques; Cycloheximide; Dactinomycin; Eflornithine; Gene Expression; Glucose; Insulin; Islets of Langerhans; Male; Mice; Mitoguazone; Polyamines; RNA, Messenger; Spermidine; Spermine

1990
Transcriptional inhibition in early chick embryos as a result of polyamine depletion.
    Developmental biology, 1986, Volume: 116, Issue:2

    Topics: Amanitins; Animals; Autoradiography; Cell Cycle; Chick Embryo; Dactinomycin; Dichlororibofuranosylbenzimidazole; DNA; Eflornithine; Electrophoresis, Agar Gel; Gene Expression Regulation; Ornithine; Polyamines; Protein Biosynthesis; Ribonucleotides; RNA; Transcription, Genetic

1986
Changes of ornithine decarboxylase activity in dorsal root ganglion cells after axon injury: possible relationship to alterations in neuronal chromatin.
    Experimental neurology, 1987, Volume: 95, Issue:2

    Topics: Animals; Autoradiography; Axons; Cell Nucleus; Dactinomycin; Eflornithine; Ganglia, Spinal; Male; Ornithine Decarboxylase; Peripheral Nerve Injuries; Rats; Rats, Inbred Strains; RNA; Time Factors

1987
Pharmacological investigations on the lipolytic and antilipolytic effects of growth hormone (GH) in chicken adipose tissue in vitro: evidence for involvement of calcium and polyamines.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:2

    Topics: Adipose Tissue; Animals; Calcimycin; Calcium; Chickens; Chlorpromazine; Cycloheximide; Dactinomycin; Eflornithine; Growth Hormone; Lipolysis; Male; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Synthesis Inhibitors; RNA; Spermidine; Verapamil

1988
Effect of RNA synthesis inhibitors on insulin-induced protein synthesis by 3T3 cells.
    The International journal of biochemistry, 1989, Volume: 21, Issue:11

    Topics: Amanitins; Animals; Cell Line; Dactinomycin; Dichlororibofuranosylbenzimidazole; Eflornithine; Fibroblasts; Insulin; Mice; Phenylalanine; Polyamines; Protein Biosynthesis; Ribosomes; RNA

1989
Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin.
    Journal of neurochemistry, 1989, Volume: 52, Issue:1

    Topics: Animals; Aspirin; Blood-Brain Barrier; Brain; Brain Injuries; Cold Temperature; Cycloheximide; Dactinomycin; Dexamethasone; Eflornithine; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; Verapamil

1989
Trypanosoma brucei brucei: regulation of ornithine decarboxylase in procyclic forms and trypomastigotes.
    Experimental parasitology, 1989, Volume: 68, Issue:4

    Topics: Animals; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Induction; Half-Life; Male; Ornithine Decarboxylase; Putrescine; Rats; Spermidine; Spermine; Trypanosoma brucei brucei

1989
Epidermal growth factor: modulator of murine embryonic palate mesenchymal cell proliferation, polyamine biosynthesis, and polyamine transport.
    Journal of cellular physiology, 1989, Volume: 140, Issue:2

    Topics: Animals; Cell Division; Cycloheximide; Dactinomycin; DNA; Dose-Response Relationship, Drug; Eflornithine; Epidermal Growth Factor; Female; Male; Mesoderm; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Polyamines; Putrescine; Time Factors

1989
Accumulation of N1-acetylspermidine in heart and spleen of isoprenaline-treated rats.
    The Biochemical journal, 1986, Aug-01, Volume: 237, Issue:3

    Topics: Animals; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Eflornithine; Female; Heart; Isoproterenol; Myocardium; Propranolol; Rats; Rats, Inbred Strains; Spermidine; Spleen

1986
Epidermal growth factor potentiates the induction of ornithine decarboxylase activity by prostaglandins in embryonic palate mesenchymal cells: effects on cell proliferation and glycosaminoglycan synthesis.
    Developmental biology, 1987, Volume: 122, Issue:2

    Topics: Animals; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprost; Dinoprostone; DNA Replication; Eflornithine; Enzyme Induction; Epidermal Growth Factor; Female; Glycosaminoglycans; Kinetics; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Palate; Pregnancy; Prostaglandins E; Prostaglandins F

1987
Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Actins; Cell Cycle; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Gene Expression Regulation; Half-Life; Histones; Humans; Ornithine Decarboxylase; Polyamines; Proto-Oncogenes; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured

1988
Role of polyamines in the stimulation of synthesis and secretion of plasminogen activator from bovine aortic endothelial cells.
    Journal of cellular physiology, 1988, Volume: 137, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Eflornithine; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Glycoproteins; Mitoguazone; Plasminogen Activators; Plasminogen Inactivators; Polyamines; Putrescine; Spermidine; Spermine

1988
Effect of 1,25-dihydroxyvitamin D on S-adenosylmethionine decarboxylase in chick intestine.
    Biochimica et biophysica acta, 1985, Sep-06, Volume: 841, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Calcitriol; Calcium; Carboxy-Lyases; Chickens; Dactinomycin; Dose-Response Relationship, Drug; Duodenum; Eflornithine; Enzyme Induction; Intestinal Absorption; Intestinal Mucosa; Kinetics; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Spermine; Steroids

1985
Ornithine decarboxylase activity in human endometrium and endometrial cancer cells.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1985, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Cell Division; Cell Line; Corpus Luteum; Cycloheximide; Dactinomycin; Eflornithine; Endometrium; Female; Follicular Phase; Humans; Molybdenum; Ornithine; Ornithine Decarboxylase; Progesterone; Putrescine; Time Factors; Uterine Neoplasms

1985
Induction of brain ornithine decarboxylase during recovery from metabolic, mechanical, thermal, or chemical injury.
    Journal of neurochemistry, 1984, Volume: 42, Issue:4

    Topics: Animals; Brain; Brain Injuries; Dactinomycin; Eflornithine; Hot Temperature; Hypoxia; Injections, Intraventricular; Male; Mannitol; Ornithine; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Stress, Mechanical

1984
Growth arrest- and polyamine-dependent expression of spermidine/spermine N1-acetyltransferase in human tumor cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:4

    Topics: Acetyltransferases; Blotting, Northern; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Enzyme Induction; Enzyme Repression; Heat-Shock Response; Humans; Polyamines; Putrescine; RNA; Spermidine; Spermine; Tumor Cells, Cultured

1996
Transcriptional mechanisms involved in the relaxant effect of zeranol on isolated rat uterus.
    General pharmacology, 1997, Volume: 28, Issue:4

    Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Inhibitors; Estrogen Antagonists; Estrogens, Non-Steroidal; Female; In Vitro Techniques; Ornithine Decarboxylase Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Tamoxifen; Transcription, Genetic; Uterus; Zeranol

1997
Pharmacological evidence for the contribution of polyamines as mediators of the transcriptional component involved in smooth muscle relaxation elicited by forskolin.
    Life sciences, 1997, Volume: 61, Issue:25

    Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Inhibitors; Female; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Transcription, Genetic

1997
Expression of the transforming growth factor-beta gene during growth inhibition following polyamine depletion.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Animals; Antibodies; Cell Division; Cell Line; Cell Nucleus; Dactinomycin; Eflornithine; Gene Expression Regulation; Half-Life; Intestinal Mucosa; Intestines; Kinetics; Polyamines; Rats; RNA, Messenger; Time Factors; Transcription, Genetic; Transforming Growth Factor beta

1998
Mechanisms involved in kaempferol-induced relaxation in rat uterine smooth muscle.
    Life sciences, 2000, Jun-08, Volume: 67, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Animals; Antimetabolites; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dideoxyadenosine; Drug Synergism; Eflornithine; Enzyme Inhibitors; Female; Flavonoids; In Vitro Techniques; Kaempferols; Muscle Relaxation; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Synthesis Inhibitors; Quercetin; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Spermine; Thionucleotides; Tosylphenylalanyl Chloromethyl Ketone; Uterine Contraction; Uterus

2000
Effect of inhibitors of polyamine biosynthesis on gibberellin-induced internode growth in light-grown dwarf peas.
    Plant & cell physiology, 1986, Volume: 27, Issue:2

    Topics: Arginine; Carboxy-Lyases; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Inhibitors; Gibberellins; Pisum sativum; Plant Growth Regulators; Polyamines; Protein Synthesis Inhibitors; Putrescine; RNA, Plant; Spermidine

1986