dactinomycin and deferoxamine

dactinomycin has been researched along with deferoxamine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's4 (21.05)18.2507
2000's9 (47.37)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Casey, JL; Harford, JB; Horowitz, JA; Klausner, RD; Koeller, DM1
Munro, H; Rogers, J1
MacDonald, RA; MacSween, RN; Pechet, GS1
Chu, LL; Fineberg, RA1
Rittling, SR; Woodworth, RC1
Henderson, BR; Kühn, LC1
Farinelli, SE; Greene, LA; Park, DS; Stefanis, L; Yan, CY1
Bonkovsky, HL; Cable, EE; Donohue, SE; Gildemeister, OS; Lambrecht, RW; Pepe, JA1
Ashcroft, M; Taya, Y; Vousden, KH1
Hirsch-Ernst, KI; Jungermann, K; Kahl, GF; Kietzmann, T; Ziemann, C1
Balkwill, FR; Grimshaw, MJ1
Dong, Z; Force, T; Nishiyama, J; Patel, Y; Saikumar, P; Semenza, GL; Venkatachalam, MA; Wang, J1
Beaumont, C; Bourgeois, M; Martin, ME; Tchernitchko, D1
Fujita, H; Furuyama, K; Hattori, T; Hida, W; Igarashi, K; Kitamuro, T; Nakayama, M; Ogawa, K; Shibahara, S; Shirato, K; Sun, J; Takahashi, K; Takeda, K; Udono-Fujimori, R1
Becker, I; Giffhorn-Katz, S; Immenschuh, S; Katz, N; Ohlmann, A1
Le, NT; Richardson, DR1
Ann, DK; Bertolami, CN; Kelly, AP; Le, AD; Messadi, DV; Tuan, TL; Wu, Y; Zhang, Q1

Reviews

1 review(s) available for dactinomycin and deferoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for dactinomycin and deferoxamine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Sep-01, Volume: 88, Issue:17

    Topics: Animals; Cell Line; Cycloheximide; Dactinomycin; Deferoxamine; Hemin; Humans; Mice; Plasmids; Protein Biosynthesis; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Receptors, Transferrin; RNA, Messenger; Transfection

1991
Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:8

    Topics: Animals; Cell Line; Dactinomycin; Deferoxamine; DNA; Ferritins; Heme; Iron; Liver Neoplasms, Experimental; Macromolecular Substances; Polyribosomes; Protein Biosynthesis; Rats; RNA, Messenger

1987
Iron metabolism by reticuloendothelial cells in vitro. Physical and chemical conditions, lipotrope deficiency, and acute inflammation.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:3

    Topics: Animals; Ascorbic Acid; Cobalt; Copper; Cysteine; Dactinomycin; Deferoxamine; Dinitrophenols; Edetic Acid; Fatty Liver; Fluorides; Fructose; Glucose; Glutathione; Hemochromatosis; Inflammation; Iodoacetates; Iron; Lipotropic Agents; Liver Cirrhosis; Lung; Macrophages; Microscopy, Electron; Potassium Permanganate; Protein Biosynthesis; Puromycin; Rabbits; RNA; Saponins; Sucrose; Surface-Active Agents; Transferrin; Trypsin

1969
On the mechanism of iron-induced synthesis of apoferritin in HeLa cells.
    The Journal of biological chemistry, 1969, Jul-25, Volume: 244, Issue:14

    Topics: Antibodies; Carbon Isotopes; Cycloheximide; Dactinomycin; Deferoxamine; Ferritins; HeLa Cells; Humans; Iron; Iron Isotopes; Leucine; Phenanthrolines; Time Factors

1969
The synthesis and turnover of ferritin in rat L-6 cells. Rates and response to iron, actinomycin D, and desferrioxamine.
    The Journal of biological chemistry, 1984, May-10, Volume: 259, Issue:9

    Topics: Animals; Cell Line; Dactinomycin; Deferoxamine; Ferritins; Iron; Kinetics; Muscles; Rats

1984
Differential modulation of the RNA-binding proteins IRP-1 and IRP-2 in response to iron. IRP-2 inactivation requires translation of another protein.
    The Journal of biological chemistry, 1995, Sep-01, Volume: 270, Issue:35

    Topics: 3T3 Cells; Animals; Cycloheximide; Cytidine Triphosphate; Dactinomycin; Deferoxamine; Iron; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Kinetics; L Cells; Melanoma, Experimental; Mercaptoethanol; Mice; Models, Structural; Protein Biosynthesis; RNA; RNA-Binding Proteins; Transcription, Genetic; Tumor Cells, Cultured

1995
Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells.
    The Journal of biological chemistry, 1996, Sep-06, Volume: 271, Issue:36

    Topics: Acetylcysteine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aurintricarboxylic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Caspase 1; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cysteine Endopeptidases; Dactinomycin; Deferoxamine; Enzyme Activation; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factors; PC12 Cells; Rats; RNA; Serpins; Viral Proteins

1996
Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins.
    European journal of biochemistry, 1996, Aug-15, Volume: 240, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cells, Cultured; Chick Embryo; Dactinomycin; Deferoxamine; Enzyme Inhibitors; Glutethimide; Heme; Heptanoates; Kinetics; Liver; Metalloporphyrins; Porphobilinogen Synthase; Regression Analysis; RNA, Messenger

1996
Stress signals utilize multiple pathways to stabilize p53.
    Molecular and cellular biology, 2000, Volume: 20, Issue:9

    Topics: Blotting, Northern; Camptothecin; Cells, Cultured; Chelating Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dactinomycin; Deferoxamine; Down-Regulation; Enzyme Inhibitors; Fibroblasts; Humans; Immunoblotting; Microscopy, Fluorescence; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Stress, Physiological; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures.
    The Biochemical journal, 2000, Sep-01, Volume: 350 Pt 2

    Topics: Animals; Arteries; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Blotting, Northern; Cells, Cultured; Chelating Agents; Cobalt; Dactinomycin; Deferoxamine; Fluorescent Dyes; Heme; Hepatocytes; Immunoblotting; Male; Nucleic Acid Synthesis Inhibitors; Oxygen; Rats; Rats, Wistar; Rhodamine 123; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Veins

2000
Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation--a potential mechanism.
    European journal of immunology, 2001, Volume: 31, Issue:2

    Topics: Catalase; Cell Cycle Proteins; Cell Hypoxia; Chemotaxis; Dactinomycin; Deferoxamine; Dual Specificity Phosphatase 1; Humans; Immediate-Early Proteins; Inflammation; Macrophages; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monocytes; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; RNA, Messenger; Tumor Necrosis Factor-alpha

2001
Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antimutagenic Agents; Apoptosis; Blotting, Northern; Cell Line; Cell Nucleus; Cells, Cultured; Chelating Agents; Cobalt; Dactinomycin; Deferoxamine; DNA-Binding Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Inhibitor of Apoptosis Proteins; Kidney; Mice; Models, Biological; Nuclear Proteins; Oxidation-Reduction; Oxygen; Protein Synthesis Inhibitors; Proteins; Rats; Stem Cells; Transcription Factors; Transcription, Genetic; Up-Regulation

2001
Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element.
    The Biochemical journal, 2002, May-01, Volume: 363, Issue:Pt 3

    Topics: Alternative Splicing; Animals; Cation Transport Proteins; Dactinomycin; Deferoxamine; Duodenum; Erythropoiesis; Gene Expression Regulation; Half-Life; HT29 Cells; Humans; Iron; Iron Chelating Agents; Iron-Binding Proteins; Kidney; Mice; Nucleic Acid Synthesis Inhibitors; Oxidants; Phenylhydrazines; Polymerase Chain Reaction; RNA, Messenger; Transfection

2002
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.
    The Journal of biological chemistry, 2003, Mar-14, Volume: 278, Issue:11

    Topics: Animals; Basic-Leucine Zipper Transcription Factors; Blotting, Northern; Blotting, Western; Cattle; Cell Line; Cobalt; Dactinomycin; Deferoxamine; Dimerization; Fanconi Anemia Complementation Group Proteins; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoxia; Interferon-gamma; Leucine Zippers; Luciferases; Membrane Proteins; Models, Genetic; Oxidative Stress; Oxygen; Promoter Regions, Genetic; Rats; RNA, Messenger; Time Factors; Transcription Factors; Transfection; Tumor Cells, Cultured

2003
Regulation of heme oxygenase-1 gene expression by anoxia and reoxygenation in primary rat hepatocyte cultures.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:5

    Topics: Allopurinol; Animals; Antioxidants; beta Carotene; Cell Hypoxia; Cells, Cultured; Cycloheximide; Dactinomycin; Deferoxamine; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; HSP70 Heat-Shock Proteins; Iron Chelating Agents; Male; Oxygen; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Reperfusion Injury

2003
Potent iron chelators increase the mRNA levels of the universal cyclin-dependent kinase inhibitor p21(CIP1/WAF1), but paradoxically inhibit its translation: a potential mechanism of cell cycle dysregulation.
    Carcinogenesis, 2003, Volume: 24, Issue:6

    Topics: Cell Cycle; Cells, Cultured; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Dactinomycin; Deferoxamine; DNA Damage; Gene Expression Regulation; Humans; Iron Chelating Agents; Isoniazid; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Biosynthesis; Receptors, Transferrin; RNA, Messenger; Tumor Suppressor Protein p53

2003
Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts.
    The Journal of investigative dermatology, 2003, Volume: 121, Issue:5

    Topics: Adult; Cell Hypoxia; Cells, Cultured; Cycloheximide; Dactinomycin; Deferoxamine; Female; Fibroblasts; Gene Expression Regulation; Half-Life; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Keloid; Male; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors

2003