dactinomycin and cyclosporine

dactinomycin has been researched along with cyclosporine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (48.72)18.2507
2000's11 (28.21)29.6817
2010's8 (20.51)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Smyth, MJ1
Norihisa, Y; Ortaldo, JR; Smyth, MJ1
Gollapudi, S; Gupta, S; Tsuruo, T1
Borger, P; Dokter, WH; Halie, MR; Hendriks, D; van der Horst, I; Vellenga, E1
Evans, GA; Farrar, WL; Wahl, LM1
Malkovsky, M; Manning, JK; Meager, A1
Hata, D; Heike, T; Higaki, Y; Horiguchi, Y; Ishigami, T; Katamura, K; Kim, KM; Mayumi, M; Mikawa, H1
Antoniadis, A; Christodoulou, D; Dimitriadou, A; Exindari, M; Haitoglou, K; Malissiovas, N; Trakatellis, A1
Jenkins, MK; Mondino, A1
Marakhova, II; Toropova, FV; Vereninov, AA; Vinogradova, TA1
Bates, SE; Dickstein, B; Fojo, AT; Lee, JS; Spolyar, M1
Cowie, F; Pinkerton, CR1
Heitman, J; Hemenway, CS1
Arron, J; Choi, Y; Wong, B1
Chan, HS; Doyle, J; Greenberg, ML; Karaskov, V; Koren, G; Malkin, D; Moncica, I; Theis, JG2
Billah, MM; Egan, RW; Nahrebne, DK; Razac, S; Shah, H; Umland, SP1
Ishaq, M; Natarajan, V; Zhang, YM1
Cosimi, AB; Ingelfinger, JR; Pascual, M; Swinford, RD; Tolkoff-Rubin, N; Williams, WW1
Chi, JG; Cho, SS; Choi, EY; Chung, DH; Hwang, DH; Jang, JJ; Jun, BH; Kim, SH; Lee, IS; Park, SH; Sohn, HW; Sung, UA1
Okunuki, H; Onose, J; Sawada, J; Teshima, R1
Gierman, JL; Jaligam, VR; Kantrow, SP; Lancaster, JR; Piantadosi, CA; Summer, WR; Zhang, P1
Mitchell, JB; Smith, J1
Basinger, SF; Le, WD; Wu, SM; Yang, CY; Yang, JH1
Adams, V; Barten, MJ; Boldt, A; Dhein, S; Gummert, JF; Mohr, FW; Sagner, A1
Manna, SK; Raghavendra, PB; Ramesh, GT; Sreenivasan, Y1
Goodisman, J; Jones, E; Souid, AK; Tao, Z1
Bryne, M; Halstensen, TS; Husvik, C1
Del Rosso, JQ; Momin, SB; Peterson, A1
Edlich, F; Falquez-Medina, H; Fimm-Todt, F; Funk, K; Jahreis, G; Klesse, R; Lauterwasser, J; Luo, X; O'Neill, K; Oelgeklaus, A; Schreiner, A; van der Laan, M; Zerbes, RM1

Reviews

3 review(s) available for dactinomycin and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Multidrug resistant gene 1 product in human T cell subsets: role of protein kinase C isoforms and regulation by cyclosporin A.
    Advances in experimental medicine and biology, 1992, Volume: 323

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cycloheximide; Cyclosporine; Dactinomycin; Drug Resistance; Gene Expression Regulation; Humans; Isoenzymes; Lymphocyte Activation; Membrane Glycoproteins; Mice; Models, Biological; Phytohemagglutinins; Protein Kinase C; T-Lymphocyte Subsets

1992
A status report on drug-associated acne and acneiform eruptions.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:6

    Topics: Acne Vulgaris; Acneiform Eruptions; Adrenal Cortex Hormones; Cyclosporine; Dactinomycin; ErbB Receptors; Humans; Lithium Carbonate; Sirolimus; Tumor Necrosis Factor-alpha

2010

Trials

1 trial(s) available for dactinomycin and cyclosporine

ArticleYear
Increased systemic toxicity of sarcoma chemotherapy due to combination with the P-glycoprotein inhibitor cyclosporin.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Cyclophosphamide; Cyclosporine; Dactinomycin; Drug Interactions; Etoposide; Fever; Humans; Ifosfamide; Immunosuppressive Agents; Neutropenia; Patient Admission; Retrospective Studies; Sarcoma; Sepsis; Soft Tissue Neoplasms; Vincristine

1998

Other Studies

35 other study(ies) available for dactinomycin and cyclosporine

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Mechanisms of cytotoxicity used by human peripheral blood T-cell subsets.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Bucladesine; CD4 Antigens; CD8 Antigens; Cholera Toxin; Cycloheximide; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Egtazic Acid; Emetine; Humans; Lymphocyte Activation; Mitomycin; T-Lymphocyte Subsets; Tumor Necrosis Factor-alpha

1992
Multiple cytolytic mechanisms displayed by activated human peripheral blood T cell subsets.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jan-01, Volume: 148, Issue:1

    Topics: Antigens, Differentiation, T-Lymphocyte; CD3 Complex; CD4-Positive T-Lymphocytes; CD8 Antigens; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Gene Expression; Granzymes; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Membrane Glycoproteins; Membrane Proteins; Mitomycin; Perforin; Pore Forming Cytotoxic Proteins; Protein Synthesis Inhibitors; Receptors, Antigen, T-Cell; Serine Endopeptidases; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; Tumor Necrosis Factor-alpha

1992
Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level.
    Blood, 1992, Dec-01, Volume: 80, Issue:11

    Topics: Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Cycloheximide; Cyclosporine; Dactinomycin; Gene Expression Regulation; Humans; Interleukin-4; Receptors, Interleukin-4; Receptors, Mitogen; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1992
Interleukin-2-dependent phosphorylation of the retinoblastoma-susceptibility-gene product p110-115RB in human T-cells.
    The Biochemical journal, 1992, Mar-15, Volume: 282 ( Pt 3)

    Topics: Cell Cycle; Cells, Cultured; Cyclosporine; Dactinomycin; Genes, Retinoblastoma; Humans; Interleukin-2; Lymphocyte Activation; Mitogens; Nuclear Proteins; Phosphorylation; Retinoblastoma Protein; Signal Transduction; Stimulation, Chemical; T-Lymphocytes

1992
Modulation of anti-tumor cytotoxicity of cultured mast cells by metabolic inhibitors.
    International archives of allergy and immunology, 1992, Volume: 98, Issue:2

    Topics: Animals; Cholera Toxin; Cyclosporine; Cytotoxicity, Immunologic; Dactinomycin; Immunity, Cellular; In Vitro Techniques; Mast Cells; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1992
Anti-IgM antibody-induced cell death in a human B lymphoma cell line, B104, represents a novel programmed cell death.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jan-15, Volume: 148, Issue:2

    Topics: Antibodies, Anti-Idiotypic; Calcium; Cell Death; Cycloheximide; Cyclosporine; Dactinomycin; DNA; DNA Damage; Humans; Immunoglobulin M; Lymphoma, B-Cell; Tumor Cells, Cultured

1992
Effect of combination of deoxypyridoxine with known anti-proliferative or immunosuppressive agents on lymphocyte serine hydroxymethyltransferase.
    Postgraduate medical journal, 1994, Volume: 70 Suppl 1

    Topics: Antineoplastic Agents; Asparaginase; Cells, Cultured; Cyclosporine; Cytarabine; Dactinomycin; Glycine Hydroxymethyltransferase; Humans; Immunosuppressive Agents; Lymphocytes; Pyridoxine

1994
Accumulation of sequence-specific RNA-binding proteins in the cytosol of activated T cells undergoing RNA degradation and apoptosis.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: Alkaloids; Animals; Antibodies, Monoclonal; Apoptosis; Base Sequence; Blotting, Northern; Columbidae; Cyclosporine; Cytochrome c Group; Cytosol; Dactinomycin; Enzyme Inhibitors; Hybridomas; Interleukin-2; Lymphocyte Activation; Lymphokines; Molecular Sequence Data; Receptors, Antigen, T-Cell; Restriction Mapping; RNA; RNA Probes; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Staurosporine; T-Lymphocytes; Uridine

1995
Long-term enhancement of Na,K-ATPase pump during blasttransformation of human lymphocytes is controlled first by translational, then by transcriptional mechanisms.
    FEBS letters, 1995, Jul-10, Volume: 368, Issue:1

    Topics: Cell Cycle; Cell Division; Cells, Cultured; Cyclosporine; Dactinomycin; Humans; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Protein Biosynthesis; Sodium-Potassium-Exchanging ATPase; Transcription, Genetic

1995
Differential modulation of P-glycoprotein transport by protein kinase inhibition.
    Biochemistry, 1993, Sep-07, Volume: 32, Issue:35

    Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carrier Proteins; Cyclosporine; Dactinomycin; Dihydropyridines; Drug Resistance; Humans; Isoenzymes; Membrane Glycoproteins; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine

1993
Enhanced toxicity of dactinomycin and vincristine by cyclosporine given to reverse multidrug resistance.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Dactinomycin; Drug Resistance; Humans; Male; Neoplasms; Vincristine

1994
Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast.
    The Journal of biological chemistry, 1996, Aug-02, Volume: 271, Issue:31

    Topics: Amino Acid Isomerases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin; Calmodulin-Binding Proteins; Carrier Proteins; Cyclosporine; Dactinomycin; DNA-Binding Proteins; Drug Resistance, Multiple; Heat-Shock Proteins; Humans; Immunosuppressive Agents; Methyltransferases; Mice; Mutation; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Plasmodium falciparum; Saccharomyces cerevisiae; Tacrolimus; Tacrolimus Binding Proteins

1996
T cell receptor signals enhance susceptibility to Fas-mediated apoptosis.
    The Journal of experimental medicine, 1997, Dec-01, Volume: 186, Issue:11

    Topics: Animals; Apoptosis; Calcium; Cyclosporine; Dactinomycin; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Fas Ligand Protein; fas Receptor; Hybridomas; Immunosuppressive Agents; Ionomycin; Ionophores; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 4, Group A, Member 1; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors

1997
Interleukin-5 mRNA stability in human T cells is regulated differently than interleukin-2, interleukin-3, interleukin-4, granulocyte/macrophage colony-stimulating factor, and interferon-gamma.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:5

    Topics: Antibodies, Monoclonal; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclosporine; Dactinomycin; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Interleukin-3; Interleukin-4; Interleukin-5; Interleukins; Kinetics; Nucleic Acid Synthesis Inhibitors; RNA, Messenger; Transcription, Genetic

1998
Activation-induced down-regulation of retinoid receptor RXRalpha expression in human T lymphocytes. Role of cell cycle regulation.
    The Journal of biological chemistry, 1998, Aug-14, Volume: 273, Issue:33

    Topics: Base Sequence; CD3 Complex; Cell Cycle; Cloning, Molecular; Cycloheximide; Cyclosporine; Dactinomycin; DNA Primers; Down-Regulation; Gene Expression Regulation; Humans; In Vitro Techniques; Lymphocyte Activation; Molecular Sequence Data; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Messenger; T-Lymphocytes

1998
Chronic rejection and chronic cyclosporin toxicity in renal allografts.
    Immunology today, 1998, Volume: 19, Issue:11

    Topics: Animals; Blotting, Northern; Cell Line; Chronic Disease; Cyclosporine; Dactinomycin; Graft Rejection; Growth Substances; Humans; Immunosuppressive Agents; Kidney Transplantation; Nucleic Acid Synthesis Inhibitors; Rats; RNA, Messenger; Transforming Growth Factor beta

1998
Engagement of CD99 induces apoptosis through a calcineurin-independent pathway in Ewing's sarcoma cells.
    The American journal of pathology, 1998, Volume: 153, Issue:6

    Topics: 12E7 Antigen; Antibodies, Monoclonal; Antigens, CD; Apoptosis; Calcineurin; Calcium; Caspase Inhibitors; Caspases; Cell Adhesion Molecules; Cell Differentiation; Cyclosporine; Dactinomycin; Fluorescent Antibody Technique, Indirect; Humans; Membrane Potentials; Microscopy, Confocal; Microscopy, Electron; Neuroblastoma; Neuroectodermal Tumors, Primitive; Sarcoma, Ewing; Tacrolimus; Tumor Cells, Cultured

1998
Effect of Ca(2+) ATPase inhibitors on MCP-1 release from bone marrow-derived mast cells and the involvement of p38 MAP kinase activation.
    International archives of allergy and immunology, 2000, Volume: 121, Issue:1

    Topics: Animals; Blotting, Western; Bone Marrow Cells; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Chemokine CCL2; Cyclosporine; Dactinomycin; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Female; Hydroquinones; Indoles; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2000
Assessment of systemic toxicity in children receiving chemotherapy with cyclosporine for sarcoma.
    Medical and pediatric oncology, 2000, Volume: 34, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Transfusion; Chi-Square Distribution; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Dactinomycin; Etoposide; Female; Fever; Humans; Ifosfamide; Male; Neutropenia; Pilot Projects; Platelet Transfusion; Retrospective Studies; Sarcoma; Sepsis; Treatment Outcome; Vincristine

2000
Regulation of tumor necrosis factor cytotoxicity by calcineurin.
    FEBS letters, 2000, Oct-20, Volume: 483, Issue:2-3

    Topics: Animals; Apoptosis; Calcineurin; Caspases; Cell Death; Cyclosporine; Cytochrome c Group; Dactinomycin; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Intracellular Membranes; L-Lactate Dehydrogenase; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Rats; Rats, Sprague-Dawley; Tacrolimus; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
D-amino acid residues in peptides and proteins.
    Proteins, 2003, Mar-01, Volume: 50, Issue:4

    Topics: Amino Acids; Artifacts; Crystallography, X-Ray; Cyclosporine; Dactinomycin; Databases, Protein; Gramicidin; Melitten; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Secondary; Proteins; Stereoisomerism

2003
Mechanisms of apoptosis in human retinal pigment epithelium induced by TNF-alpha in conditions of heavy metal ion deficiency.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:3

    Topics: Apoptosis; Caspase 3; Caspases; Cell Line; Chelating Agents; Cyclosporine; Dactinomycin; Drug Combinations; Enzyme Activation; Ethylenediamines; Fluorescent Dyes; Humans; Ion Channels; Membrane Potentials; Metals, Heavy; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pigment Epithelium of Eye; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2005
The influence of immunosuppressive drugs on T- and B-cell apoptosis via p53-mediated pathway in vitro and in vivo.
    Transplantation, 2006, Aug-15, Volume: 82, Issue:3

    Topics: Apoptosis; B-Lymphocytes; Cyclosporine; Dactinomycin; Drug Therapy, Combination; Heart Transplantation; Humans; Immunosuppressive Agents; Mycophenolic Acid; Signal Transduction; T-Lymphocytes; Tacrolimus; Tumor Suppressor Protein p53

2006
Cardiac glycoside induces cell death via FasL by activating calcineurin and NF-AT, but apoptosis initially proceeds through activation of caspases.
    Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:2

    Topics: Antibodies; Apoptosis; bcl-X Protein; Calcineurin; Calcineurin Inhibitors; Calcium; Cardenolides; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Nucleus; Cyclosporine; Dactinomycin; DNA; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lipids; Membrane Fluidity; Necrosis; NFATC Transcription Factors; Oligopeptides; Protein Transport; Sodium-Potassium-Exchanging ATPase

2007
Quantitative measure of cytotoxicity of anticancer drugs and other agents.
    Analytical biochemistry, 2008, Oct-01, Volume: 381, Issue:1

    Topics: Antineoplastic Agents; Caffeine; Cell Death; Cell Respiration; Cyclosporine; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Jurkat Cells; Platinum Compounds; Tirapazamine; Triazines

2008
c-Jun N-terminal kinase negatively regulates epidermal growth factor-induced cyclooxygenase-2 expression in oral squamous cell carcinoma cell lines.
    European journal of oral sciences, 2009, Volume: 117, Issue:6

    Topics: Anthracenes; Calcineurin Inhibitors; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Cyclosporine; Dactinomycin; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mouth Neoplasms; NFATC Transcription Factors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Transcription, Genetic

2009
Hexokinases inhibit death receptor-dependent apoptosis on the mitochondria.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 08-17, Volume: 118, Issue:33

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line; Cyclosporine; Dactinomycin; Doxorubicin; Enzyme Inhibitors; Fas Ligand Protein; Gene Deletion; Gene Expression Regulation, Enzymologic; Hexokinase; Humans; Mitochondria; TNF-Related Apoptosis-Inducing Ligand

2021