Compounds > dactinomycin

dactinomycin and chenodeoxycholic acid

dactinomycin has been researched along with chenodeoxycholic acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Campana, G; Di Toro, R; Murari, G; Spampinato, S1
Kim, KH; Kwon, TK; Lee, SJ; Park, BJ; Park, SW; Roh, JL; Sung, MW1
Abe, T; Goto, J; Hishinuma, T; Kobayashi, M; Mano, N; Okada, M; Takeuchi, T; Unno, M; Yamaguchi, H1

Reviews

1 review(s) available for dactinomycin and chenodeoxycholic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for dactinomycin and chenodeoxycholic acid

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Effects of specific bile acids on c-fos messenger RNA levels in human colon carcinoma Caco-2 cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 11, Issue:4

    Topics: Bile Acids and Salts; Caco-2 Cells; Chenodeoxycholic Acid; Cholagogues and Choleretics; Dactinomycin; Dose-Response Relationship, Drug; Genes, fos; Humans; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; RNA, Messenger; Transcription, Genetic; Ursodeoxycholic Acid

2000
Bile acid induces cyclo-oxygenase-2 expression in cultured human pharyngeal cells: a possible mechanism of carcinogenesis in the upper aerodigestive tract by laryngopharyngeal reflux.
    The Laryngoscope, 2003, Volume: 113, Issue:6

    Topics: Bile Acids and Salts; Cell Transformation, Neoplastic; Chenodeoxycholic Acid; Cyclooxygenase 2; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Esophageal Neoplasms; Gastroesophageal Reflux; Humans; Isoenzymes; Laryngeal Neoplasms; Larynx; Membrane Proteins; Pharyngeal Neoplasms; Pharynx; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tumor Cells, Cultured

2003
Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.
    Cancer letters, 2008, Feb-18, Volume: 260, Issue:1-2

    Topics: Antineoplastic Agents; Camptothecin; Chenodeoxycholic Acid; Dactinomycin; Docetaxel; Fluorescent Dyes; Humans; Irinotecan; Kinetics; Lysine; Mitoxantrone; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Signal Processing, Computer-Assisted; Solute Carrier Organic Anion Transporter Family Member 1B3; Spectrometry, Fluorescence; Taxoids; Transfection

2008