dactinomycin has been researched along with caffeine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (71.43) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 3 (7.14) | 29.6817 |
| 2010's | 7 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Götz von Olenhusen, KG; Jücker, H; Wohlfarth-Bottermann, KE | 1 |
| Claycomb, WC | 1 |
| Clarke, CH; Shankel, DM | 1 |
| Dewey, WC; Tomasovic, SP | 1 |
| Kohn, KW; Ross, WE; Zwelling, LA | 1 |
| Chubykin, VL; Lebedeva, LI | 1 |
| Allewell, NM; Oles, J; Wolfe, J | 1 |
| Aĭrapetian, LG; Sevan'kaev, AV | 1 |
| Belyaeva, ES; Semeshin, VF; Sherudilo, AI | 1 |
| Sancar, A; Selby, CP | 1 |
| Craig, RW; Kastan, MB; Onyekwere, O; Sidransky, D; Vogelstein, B | 1 |
| Pardee, AB; Schlegel, R | 1 |
| Johnson, MD; Lambert, ME; Okin, E; Ronai, ZA; Weinstein, IB | 1 |
| Delbono, O; Muchnik, S; Obejero Paz, CA | 1 |
| Ono, J; Shimazu, Y | 1 |
| Davies, DR | 1 |
| Arlett, CF | 2 |
| Cleaver, JE | 1 |
| Oliver, IT; Yeung, D | 1 |
| Fukui, N | 1 |
| Sasaki, MS; Tonomura, A | 1 |
| Kiefer, J | 1 |
| Bootsma, D; Hoeksema, JL; Kleijer, WJ; Sluyter, ML | 1 |
| Jeter, WS; Klesius, PH; Laux, DC | 1 |
| Oravec, M; Sourkes, TL; Young, SN | 1 |
| Rahwan, RG | 1 |
| Nishikawa, H; Shio, I | 1 |
| Dehn, F; LeValley, SE; Lombrozo, L; Mitoma, C | 1 |
| Best, JB; Morita, M | 1 |
| Kleppe, K; Lossius, I; Sandlie, I; Sjåstad, K | 1 |
| Mathinos, PR; Randall, JL; Ritter, EJ; Scott, WJ; Wilson, JG | 1 |
| Bedner, E; Darzynkiewicz, Z; Du, L; Traganos, F | 1 |
| Huseby, NE; Johannessen, M; Moens, U; Pandur, S; Pankiv, S | 1 |
| Goodisman, J; Jones, E; Souid, AK; Tao, Z | 1 |
| Ma, H; Pederson, T | 1 |
| Kovalev, VI; Vekshin, NL | 1 |
4 review(s) available for dactinomycin and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antimutagenesis in microbial systems.
Topics: Acridines; Antipsychotic Agents; Bacteria; Caffeine; Chloramphenicol; Dactinomycin; Dibenzocycloheptenes; DNA Repair; Escherichia coli; Fungi; Genes; Histidine; Manganese; Mutagens; Mutation; Phenothiazines; Polyamines; Purine Nucleosides; Quinacrine; Radiation Effects; Rosaniline Dyes; Ultraviolet Rays; Uracil; Warfarin | 1975 |
The biochemical and pharmacological basis of learning and memory.
Topics: Amphetamine; Azaguanine; Brain Chemistry; Caffeine; Cycloheximide; Dactinomycin; Glutamates; Learning; Memory; Memory, Short-Term; Nerve Tissue Proteins; Neurons; Pemoline; Puromycin; Quaternary Ammonium Compounds; RNA; Strychnine; Time Factors; Vitamin B 12 | 1971 |
Planarians as a model system for in vitro teratogenesis studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Behavior, Animal; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cadmium; Caffeine; Chlordan; Colchicine; Dactinomycin; Demecolcine; Drug Evaluation, Preclinical; Ethanol; Lead; Mercury; Models, Biological; Planarians; Puromycin; Reproduction; Teratogens; Thalidomide; Turbellaria | 1982 |
38 other study(ies) available for dactinomycin and caffeine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Induction of a plasmodial stage of Physarum without plasmalemma invaginations.
Topics: Caffeine; Cell Membrane; Cytoplasm; Cytoskeleton; Dactinomycin; Microscopy, Electron; Movement; Physarum; Time Factors | 1979 |
Poly(adenosine diphosphate ribose) polymerase activity and nicotinamide adenine dinucleotide in differentiating cardiac muscle.
Topics: Adenosine Triphosphate; Animals; Bucladesine; Caffeine; Cell Differentiation; Cell Nucleus; Dactinomycin; DNA; DNA Nucleotidyltransferases; Heart; Isoproterenol; Myocardium; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Proteins; Rats; Theophylline; Thymidine; Xanthines | 1976 |
Comparative studies of the effects of drugs on X-ray-induced G2 delay.
Topics: Benzimidazoles; Caffeine; Cell Cycle; Cells, Cultured; Dactinomycin; Deoxyadenosines; Dimethyl Sulfoxide; Lucanthone; Mitosis; RNA; Sulfhydryl Compounds; Theophylline; Time Factors; X-Rays | 1978 |
Relationship between cytotoxicity and DNA strand breakage produced by adriamycin and other intercalating agents.
Topics: Animals; Caffeine; Cell Survival; Cells, Cultured; Dactinomycin; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Doxorubicin; Drug Interactions; Ellipticines; Intercalating Agents; Leukemia L1210; Mice | 1979 |
[Formation of structural chromosome mutations in metaphase of mitosis].
Topics: Acridine Orange; Animals; Caffeine; Cells, Cultured; Chromosome Aberrations; Chromosomes; Dactinomycin; Ethidium; Fibroblasts; Hydroxylamines; Metaphase; Mice; Mice, Inbred BALB C; Mutation; Puromycin; Ultraviolet Rays | 1979 |
A physicochemical analysis of conjugation in Tetrahymena pyriformis.
Topics: Amino Acids; Animals; Caffeine; Calcium; Colchicine; Conjugation, Genetic; Culture Media; Cycloheximide; Dactinomycin; Dithiothreitol; Egtazic Acid; Kinetics; Magnesium; Manganese; Potassium; Sodium; Temperature; Tetrahymena pyriformis; Theophylline; Zinc | 1976 |
[Action of caffeine and actinomycin D on the frequency of chromosome aberrations in a human lymphocyte culture after irradiation at various stages of the cell cycle].
Topics: Caffeine; Cells, Cultured; Chromosome Aberrations; Dactinomycin; Gamma Rays; Humans; Lymphocytes; Mitosis; Time Factors | 1977 |
Nucleoli formation under inhibited RNA synthesis.
Topics: Caffeine; Cell Line; Cell Nucleolus; Cell Nucleus; Dactinomycin; Diploidy; Dose-Response Relationship, Drug; Mitosis; RNA | 1975 |
Noncovalent drug-DNA binding interactions that inhibit and stimulate (A)BC excinuclease.
Topics: Binding Sites; Bisbenzimidazole; Caffeine; Dactinomycin; DNA; DNA Repair; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Ethidium; Intercalating Agents; Kinetics; Plasmids; Protein Binding | 1991 |
Participation of p53 protein in the cellular response to DNA damage.
Topics: Bone Marrow Cells; Caffeine; Cell Cycle; Cycloheximide; Dactinomycin; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Exons; Flow Cytometry; Genes, p53; Humans; Mutation; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1991 |
Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells.
Topics: Animals; Caffeine; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; DNA Replication; Interphase; Mitosis; RNA | 1986 |
Induction of asynchronous replication of polyoma DNA in rat cells by ultraviolet irradiation and the effects of various inhibitors.
Topics: Animals; Base Sequence; Caffeine; Cell Line; Cycloheximide; Dactinomycin; DNA; DNA Damage; DNA Replication; Polyomavirus; Rats; Ultraviolet Rays; Virus Replication | 1987 |
Effects of actinomycin D on contractile properties of denervated rat skeletal muscle.
Topics: Animals; Caffeine; Dactinomycin; Membrane Potentials; Muscle Contraction; Muscle Denervation; Muscles; Organ Size; Rats; Rats, Inbred Strains | 1986 |
Ultraviolet reactivation of a bacteriophage containing a single-stranded deoxyribonucleic acid as a genetic element.
Topics: Caffeine; Chloramphenicol; Coliphages; Dactinomycin; DNA, Viral; In Vitro Techniques; Radiation Effects; Ultraviolet Rays | 1966 |
Repair mechanisms and variations in UV sensitivity within the cell cycle.
Topics: Acridines; Caffeine; Cell Division; Chloramphenicol; Dactinomycin; DNA; Eukaryota; Light; Radiation Genetics; Ultraviolet Rays | 1965 |
A failure of specific inhibitors to affect survival of Chinese hamster cells exposed to ultra-violet light.
Topics: Acridines; Animals; Caffeine; Chloramphenicol; Clone Cells; Cricetinae; Cycloheximide; Dactinomycin; Puromycin; Radiation Effects; Theophylline; Ultraviolet Rays | 1967 |
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Depression; DNA; DNA Replication; Floxuridine; Gentian Violet; HeLa Cells; Humans; Hydroxyurea; Iodoacetates; L Cells; Mice; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |
Induction of phosphopyruvate carboxylase in neonatal rat liver by adenosine 3',5'-cyclic monophosphate.
Topics: Adenine Nucleotides; Animals; Animals, Newborn; Caffeine; Carboxy-Lyases; Cyclic AMP; Dactinomycin; Enzyme Induction; Ergotamine; Fetus; Fructose-Bisphosphatase; Insulin; Liver; Nitrogen; Nucleotides; Prostaglandins; Pyruvate Kinase; Pyruvates; Radioisotopes; Rats | 1968 |
Factors regulating thymidine kinase in regenerating liver.
Topics: Adrenocorticotropic Hormone; Animals; Caffeine; Carbon Isotopes; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Female; Growth Hormone; Hepatectomy; Hypophysectomy; In Vitro Techniques; Liver; Liver Regeneration; Rats; Thymidine; Thymidine Kinase; Tritium | 1971 |
A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.
Topics: Alkanesulfonates; Alkylating Agents; Anemia, Aplastic; Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Chloramphenicol; Chromosome Aberrations; Chromosomes; Cobalt Isotopes; Dactinomycin; DNA Repair; Humans; Lymphocytes; Mechlorethamine; Methoxsalen; Mitomycins; Nitrosoguanidines; Quinolines; Radiation Effects; Ultraviolet Rays | 1973 |
The effect of some nucleic acid-binding metabolic inhibitors on split-dose sparing in u.v.-and electron-irradiated diploid yeast.
Topics: Acridines; Anaerobiosis; Caffeine; Dactinomycin; Diploidy; DNA Repair; Electrons; Formaldehyde; Hydroxylamines; Radiation Dosage; Radiation Effects; Saccharomyces cerevisiae; Ultraviolet Rays | 1973 |
Effects of inhibitors on repair of DNA in normal human and xeroderma pigmentosum cells after exposure to x-rays and ultraviolet irradiation.
Topics: Acridines; Anti-Bacterial Agents; Caffeine; Cells, Cultured; Dactinomycin; Dinitrophenols; DNA; DNA Repair; Edetic Acid; Fibroblasts; Gentian Violet; HeLa Cells; Humans; Iodoacetates; Kidney; Potassium; Radiation Dosage; Ultraviolet Rays; Xeroderma Pigmentosum | 1973 |
Suppressive effects of caffeine on the immune response of the mouse to sheep erythrocytes.
Topics: Animals; Antibody Formation; Caffeine; Carbon Radioisotopes; Cells, Cultured; Dactinomycin; Depression, Chemical; DNA; Erythrocytes; Hemolysin Proteins; Immunization; Immunosuppressive Agents; Isoleucine; Mice; Protein Biosynthesis; Puromycin; Sheep; Spleen; Thymidine; Tritium; Uridine | 1973 |
The effect of theophylline on tryptophan pyrrolase in the hypophysectomized rat and some observations on the validity of tryptophan pyrrolase assays.
Topics: Animals; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Paper; Cycloheximide; Dactinomycin; Enzyme Activation; Hydrocortisone; Hypophysectomy; Kinetics; Liver; Male; Models, Chemical; Perfusion; Pituitary Gland; Rats; Theophylline; Tryptophan; Tryptophan Oxygenase | 1974 |
Effect of caffeine on adenylosuccinate lyase synthesis in Bacillus subtilis.
Topics: Bacillus subtilis; Caffeine; Culture Media; Dactinomycin; Lyases; Nucleosides; Nucleotides; Oxidoreductases; Puromycin; Succinates; Theobromine; Theophylline; Time Factors; Transferases; Xanthines | 1969 |
The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation.
Topics: Acridines; Animals; Caffeine; Chloramphenicol; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; Hydroxylamines; Hydroxyurea; Protein Binding; Protein Biosynthesis; Puromycin; Radiation Effects; Temperature; Thymidine | 1970 |
Nature of the effect of caffeine on the drug-metabolizing enzymes.
Topics: 17-Hydroxycorticosteroids; Acetanilides; Amino Acids; Aminopyrine; Aniline Compounds; Animals; Caffeine; Cytochromes; Dactinomycin; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Methylation; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnanes; Pyridones; Rats; Stimulation, Chemical; Time Factors; Zoxazolamine | 1969 |
Mechanism of caffeine-induced inhibition of DNA synthesis in escherichia coli.
Topics: Caffeine; Dactinomycin; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Kinetics; Nalidixic Acid; Novobiocin | 1983 |
Potentiative interactions between caffeine and various teratogenic agents.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Emetine; Female; Fetal Death; Floxuridine; Hydroxyurea; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry.
Topics: Caffeine; Dactinomycin; DNA; Electrophoresis, Agar Gel; Flow Cytometry; Fluorescence; Fluorescent Dyes; HL-60 Cells; Humans; Intercalating Agents; Kinetics; Lasers; Models, Chemical; Propidium; Staining and Labeling | 2001 |
Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells.
Topics: Animals; Caffeine; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cycloheximide; Dactinomycin; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Oxidative Stress; ras Proteins; Rats; RNA, Messenger; Signal Transduction; Vitamin K 3 | 2007 |
Quantitative measure of cytotoxicity of anticancer drugs and other agents.
Topics: Antineoplastic Agents; Caffeine; Cell Death; Cell Respiration; Cyclosporine; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Jurkat Cells; Platinum Compounds; Tirapazamine; Triazines | 2008 |
The nucleolus stress response is coupled to an ATR-Chk1-mediated G2 arrest.
Topics: Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Proteins; Cell Nucleolus; Checkpoint Kinase 1; Dactinomycin; DNA Damage; G2 Phase Cell Cycle Checkpoints; HeLa Cells; Histones; Humans; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Single-Cell Analysis; Stress, Physiological | 2013 |
Nucleotide carriers for anti-tumour actinomycin antibiotics.
Topics: Adenine; Antibiotics, Antineoplastic; Caffeine; Dactinomycin; DNA; Drug Carriers; Fluorescent Dyes; Folic Acid; Guanine; Nucleotides; Thymine | 2016 |