dactinomycin has been researched along with benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 20 (68.97) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Biemann, HP; Blenis, J; Davis, RJ; Juo, P; Konz, RF; Kuo, CJ; Raingeaud, J; Reynolds, SE | 1 |
| Amarante-Mendes, GP; Cotter, TG; Finucane, DM; Green, DR; Martin, SJ; Salvesen, GS | 1 |
| Diaz, C; Lee, AT; McConkey, DJ; Schroit, AJ | 1 |
| Alnemri, ES; Chen, M; Itoh, T; Moran, J; Pleasure, D; Reddy, UR | 1 |
| Beyaert, R; Contreras, R; De Valck, D; Fiers, W; Heyninck, K; Jeang, KT; Jin, DY; Van de Craen, M | 1 |
| Canzoniero, LM; Choi, WS; Gwag, BJ; Kim, JE; Lee, EB; O'Malley, KL; Oh, TH; Oh, YJ; Sensi, SL; Sohn, S | 1 |
| Adams, JM; Ofir, R; Zhang, LC | 1 |
| Dallaporta, B; Daugas, E; Kroemer, G; Loeffler, M; Maisse, C; Pablo, M; Zamzami, N | 1 |
| Billiar, TR; Li, J; Yang, S | 1 |
| Campbell, JS; Chaisson, M; Fausto, N; Franklin, CC; Kavanagh, TJ; Pierce, RH; Poot, M; Rabinovitch, PS; Stephenson, AB | 1 |
| Colombo, B; Corti, A; Curnis, F; Manfredi, AA; Pelagi, M; Rovere, P; Sacchi, A | 1 |
| Goldstein, JC; Green, DR; Newmeyer, DD; Schuler, M; von Ahsen, O; Waterhouse, NJ | 1 |
| Belka, C; Berdel, WE; Kreuter, M; Los, M; Renz, A; Schulze-Osthoff, K | 1 |
| Baba, K; Goto, Y; Masuda, K; Mizuno, T; Ohno, K; Tsujimoto, H | 1 |
| Filgueira, L; Forte, P; Groscurth, P; Matter-Reissmann, UB; Schneider, MK; Seebach, JD | 1 |
| Gottlieb, RA; Green, DR; Ricci, JE | 1 |
| Li, D; Mehta, JL; Shokeen, M; Zhang, W | 1 |
| Fei, XF; Ikejima, T; Li, TJ; Minami, M; Tashiro, S; Wang, BX; Xing, DJ | 1 |
| Brown, TL; Caserta, TM; Gultice, AD; Reedy, MA; Smith, AN | 1 |
| Hoffarth, S; Huber, C; Milosevic, J; Schuler, M | 1 |
| Ahn, J; Choi, J; Joo, CH; Kim, D; Kim, YK; Lee, H; Seo, I; Yoon, SY | 1 |
| Andreau, K; Castedo, M; Kroemer, G; Larochette, N; Perfettini, JL; Pichart, E; Roumier, T; Souquere, S; Vivet, S | 1 |
| Algeciras-Schimnich, A; Barnhart, BC; Hakem, R; Peter, ME; Pietras, EM; Salmena, L; Sayama, K | 1 |
| Eley, A; Geary, I; Hakimi, H; Hosseinzadeh, S; Pacey, AA | 1 |
| Bhalla, K; Blagosklonny, MV; Broude, EV; Demidenko, ZN; Halicka, HD; Li, CJ; Vivo, C | 1 |
| Greco, NJ; Kurtz, J; Lee, WR; Moroff, G; Seetharaman, S | 1 |
| Liu, S; Liu, Y; Wang, MJ; Zheng, D | 1 |
| Adhikari, A; Davie, J; Kazim, N; Oh, TJ | 1 |
| Chang, H; Qiu, J; Sun, F; Tian, K; Wang, W; Zha, D; Zhou, K | 1 |
29 other study(ies) available for dactinomycin and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone
| Article | Year |
|---|---|
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caenorhabditis elegans Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 1; Caspases; Cysteine Endopeptidases; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Helminth Proteins; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyridines; Serpins; Signal Transduction; Sorbitol; Transcription, Genetic; Viral Proteins | 1997 |
Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death.
Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Etoposide; fas Receptor; HL-60 Cells; Humans; Jurkat Cells; Neoplasms; Oncogenes; Staurosporine | 1998 |
Phosphatidylserine externalization during differentiation-triggered apoptosis of erythroleukemic cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; bcl-X Protein; Caspase Inhibitors; Cell Differentiation; Cell Membrane; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Erythropoiesis; Gene Expression; Genes, bcl-2; Hemin; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Phosphatidylserines; Proto-Oncogene Proteins c-bcl-2 | 1999 |
Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bucladesine; Calcium; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Colforsin; Coumarins; Cyclic AMP; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Gene Expression Regulation, Enzymologic; Neurons; Oligopeptides; Potassium; Protein Synthesis Inhibitors; Rats; Transcription, Genetic | 1999 |
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.
Topics: 3T3 Cells; Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Carrier Proteins; Caspases; Cell Line; Cloning, Molecular; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; DNA-Binding Proteins; DNA, Complementary; fas Receptor; Genes; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Oligonucleotides, Antisense; Protein Binding; Protein Processing, Post-Translational; Proteins; Recombinant Fusion Proteins; RNA, Messenger; Saccharomyces cerevisiae; Serpins; Substrate Specificity; Transfection; Tumor Necrosis Factor alpha-Induced Protein 3; Tumor Necrosis Factor-alpha; Viral Proteins; Zinc Fingers | 1999 |
Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Chloromethyl Ketones; Animals; bcl-2-Associated X Protein; Calcium; Caspases; Cell Death; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Cytosol; Dactinomycin; Dopamine; Dopamine Agents; Emetine; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Mesencephalon; Mice; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 1999 |
Interference with gene expression induces rapid apoptosis in p53-null T lymphoma cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cycloheximide; Dactinomycin; Enzyme Activation; Gene Expression Regulation, Neoplastic; JNK Mitogen-Activated Protein Kinases; Lymphoma, T-Cell; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Suppressor Protein p53 | 1999 |
Proteasome activation as a critical event of thymocyte apoptosis.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Catalase; Cells, Cultured; Cysteine Endopeptidases; Dactinomycin; Dexamethasone; Enzyme Activation; Etoposide; fas Receptor; Female; Mice; Mice, Inbred BALB C; Mitochondria; Multienzyme Complexes; Proteasome Endopeptidase Complex; T-Lymphocytes | 2000 |
Cyclic nucleotides suppress tumor necrosis factor alpha-mediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytochrome c Group; Dactinomycin; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Insulin; Liver; Male; Nucleic Acid Synthesis Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Dactinomycin; DNA-Binding Proteins; Enzyme Activation; Glutathione; Homeostasis; I-kappa B Proteins; Intracellular Membranes; Liver; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondria; NADP; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Protein Binding; Reactive Oxygen Species; Thioctic Acid; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2000 |
Caspase inhibition reveals functional cooperation between p55- and p75-TNF receptors in cell necrosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies, Monoclonal; Antigens, CD; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Cytotoxicity Tests, Immunologic; Dactinomycin; Humans; Mice; Mice, Inbred C57BL; Models, Biological; Necrosis; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cells, Cultured; Cytochrome c Group; Dactinomycin; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Green Fluorescent Proteins; Humans; Intracellular Membranes; Luminescent Proteins; Membrane Potentials; Mice; Microscopy, Confocal; Mitochondria; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Time Factors; Uncoupling Agents | 2001 |
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.
Topics: Adult; Aged; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Biomarkers; Biomarkers, Tumor; Chick Embryo; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; Dactinomycin; Enzyme Inhibitors; Extracellular Space; Female; Hematologic Neoplasms; Humans; Hydrogen Peroxide; Jurkat Cells; L Cells; L-Lactate Dehydrogenase; Male; Mice; Middle Aged; Mitochondria; Necrosis; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Protein Transport; Staurosporine; Tumor Necrosis Factor-alpha | 2001 |
TNF-alpha-induced cell death in feline immunodeficiency virus-infected cells is mediated by the caspase cascade.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cats; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Drug Interactions; Fibroblasts; Immunodeficiency Virus, Feline; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Tumor Necrosis Factor; Transfection; Tumor Necrosis Factor-alpha | 2001 |
Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression.
Topics: Amino Acid Chloromethyl Ketones; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antigens, Heterophile; Apoptosis; Calcium; Cells, Cultured; Coculture Techniques; Cysteine Endopeptidases; Cytotoxicity, Immunologic; Dactinomycin; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; Fas Ligand Protein; Genes, bcl-2; Graft Rejection; Granzymes; Humans; Killer Cells, Natural; Macrolides; Membrane Glycoproteins; Microscopy, Electron; Necrosis; Perforin; Pore Forming Cytotoxic Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Serine Endopeptidases; Staurosporine; Swine; Tumor Necrosis Factor-alpha; Ubiquitin | 2002 |
Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cytochrome c Group; Dactinomycin; Dose-Response Relationship, Drug; Electron Transport; HeLa Cells; Humans; Membrane Potentials; Mitochondria; Models, Biological; Oxygen; Oxygen Consumption; Protein Synthesis Inhibitors; Reactive Oxygen Species; Recombinant Proteins; Ultraviolet Rays | 2003 |
Identification of apoptosis-inducing factor in human coronary artery endothelial cells.
Topics: Amino Acid Chloromethyl Ketones; Angiotensin II; Apoptosis; Apoptosis Inducing Factor; Arteries; Base Sequence; Coronary Circulation; Cysteine Proteinase Inhibitors; Dactinomycin; Endothelium, Vascular; Flavoproteins; Gene Expression Regulation; Humans; Lipoproteins, LDL; Membrane Proteins; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Tumor Necrosis Factor-alpha; Up-Regulation | 2003 |
Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells.
Topics: Alkaloids; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Division; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Evodia; Fibrosarcoma; Fluorouracil; Furans; Gene Expression Regulation, Neoplastic; Genes, bcl-2; HeLa Cells; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Indole Alkaloids; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Melanoma; Mice; Mitochondria; Molecular Structure; Neoplasm Proteins; Oligopeptides; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Rats; Rats, Inbred BUF; Sarcoma 180; Tumor Cells, Cultured | 2003 |
Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzyl Compounds; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Humans; Hydrocarbons, Fluorinated; Jurkat Cells; Mice; Nucleic Acid Synthesis Inhibitors; Quinolines; Rats; Thapsigargin; Transforming Growth Factor beta | 2003 |
The DNA damage-induced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspases.
Topics: Adenocarcinoma; Adenoviridae; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Caspase Inhibitors; Caspases; Cell Transplantation; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Gene Deletion; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; Proteins; Proto-Oncogene Proteins c-bcl-2; Transplantation, Heterologous; Tumor Cells, Cultured; Ultraviolet Rays | 2003 |
Susceptibility of mouse primary cortical neuronal cells to coxsackievirus B.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Cerebral Cortex; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Dactinomycin; Enterovirus B, Human; Mice; Mice, Inbred BALB C; Neurons; Vero Cells; Virus Replication | 2004 |
Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Cell Nucleus; Chromatin; Cisplatin; Cytochromes c; Dactinomycin; DNA; DNA Damage; DNA Fragmentation; DNA Repair; Enzyme Activation; Flow Cytometry; HeLa Cells; Histones; Humans; Matrix Metalloproteinases; Membrane Potentials; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Mitochondria; Phosphatidylserines; Phosphorylation; Protein Binding; RNA, Small Interfering; Staurosporine; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2004 |
CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8.
Topics: Alleles; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Apoptosis; Caspase 8; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Death Domain Receptor Signaling Adaptor Proteins; Drug Resistance, Neoplasm; Enzyme Activation; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mitochondria; Mutation; NF-kappa B; Oligopeptides; Receptors, Tumor Necrosis Factor | 2005 |
Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Chlamydia trachomatis; Cycloheximide; Cysteine Proteinase Inhibitors; Dactinomycin; Ejaculation; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipopolysaccharides; Male; Protein Synthesis Inhibitors; Spermatozoa; Staurosporine; Substrate Specificity | 2005 |
Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor- and cycle-arrest-mediated cytoprotection.
Topics: Amino Acid Chloromethyl Ketones; Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Caspase 9; Caspase Inhibitors; Cell Cycle; Cell Line, Tumor; Cytoprotection; Dactinomycin; Doxorubicin; Enzyme Activation; Flavonoids; HSP70 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Paclitaxel; Piperidines; Protein Biosynthesis; RNA, Small Interfering; Transcriptional Activation | 2006 |
Evaluation of the reactivity of apoptosis markers before and after cryopreservation in cord blood CD34(+) cells.
Topics: Amino Acid Chloromethyl Ketones; Antigens, CD34; Apoptosis; Biomarkers; Cell Separation; Cell Survival; Cryopreservation; Dactinomycin; Dose-Response Relationship, Drug; Fetal Blood; Flow Cytometry; Humans | 2006 |
Actinomycin D enhances TRAIL-induced caspase-dependent and -independent apoptosis in SH-SY5Y neuroblastoma cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cell Line, Tumor; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Neuroblastoma; Protein Synthesis Inhibitors; Reactive Oxygen Species; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Transfection | 2007 |
The transcription elongation factor TCEA3 induces apoptosis in rhabdomyosarcoma.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dactinomycin; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Rhabdomyosarcoma; Transcriptional Elongation Factors; Up-Regulation | 2020 |
Caspase inhibitor z-VAD-FMK increases the survival of hair cells after Actinomycin-D-induced damage in vitro.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Survival; Cochlear Nerve; Culture; Cysteine Proteinase Inhibitors; Dactinomycin; Hair Cells, Auditory; Humans; Infant, Newborn; Organ of Corti; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spiral Ganglion | 2020 |