dactinomycin and azacitidine

dactinomycin has been researched along with azacitidine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199025 (73.53)18.7374
1990's1 (2.94)18.2507
2000's1 (2.94)29.6817
2010's7 (20.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Boutwell, RK; O'Brien, TG; Simsiman, RC1
Furusawa, E; Furusawa, S; Lee, JY; Suzuki, N1
Borsos, T; Ohanian, SH; Segerling, M2
Cihak, A1
Poirier, LA; Waalkes, MP1
Daneo-Moore, L; Higgins, ML3
Cavia, E; Webb, TE1
Martin, DW; Owen, NT1
Daneo-Moore, L; Sayare, M; Shockman, GD1
Cihák, A; Veselý, J1
Karlan, D; Penman, S; Reichman, M1
Cihák, A; Garret, C; Pitot, HC1
Penman, S; Reichman, M1
Cihák, A; Harrap, KR; Veselý, J1
Boothby, D; Daneo-Moore, L; Higgins, ML; Shockman, GD1
Pitot, HC; Weiss, JW1
Lu, LJ; Randerath, K1
Coy, K; Gupta, KC; Hershey, H; Levine, RA; Olivelle, S; Taylor, MW; Zawistowich, L1
Brawner, TA; Fleming, TP; Hollingshead, PG1
Schmidt, SY1
De Petrocellis, B; Maharajan, V; Pratibha, M1
Coy, K; Hershey, H; Levine, RA; Olivelle, S; Taylor, MW1
Lee, SW; Park, JH1
Brodská, B; Holoubek, A1
Bendinelli, P; Desiderio, MA; Locatelli, A; Maroni, P; Matteucci, E1
Ayupe, AC; Beckedorff, FC; Camargo, L; Reis, EM; Tahira, AC; Verjovski-Almeida, S1

Reviews

1 review(s) available for dactinomycin and azacitidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

33 other study(ies) available for dactinomycin and azacitidine

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Adenosylmethionine Decarboxylase; Animals; Azacitidine; Carboxy-Lyases; Carcinogens; Chick Embryo; Croton Oil; Cycloheximide; Dactinomycin; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Induction; Female; Half-Life; Mice; Ornithine Decarboxylase; Phorbols; RNA; Skin; Time Factors

1975
Combination chemotherapy of Rauscher leukemia and ascites tumors by narcissus alkaloid with standard drugs and effect on cellular immunity.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:3

    Topics: Alkaloids; Animals; Antineoplastic Agents; Azacitidine; Blood Cells; Carcinoma, Ehrlich Tumor; Carmustine; Cells, Cultured; Cyclophosphamide; Dactinomycin; Daunorubicin; Drug Synergism; Drug Therapy, Combination; Emetine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Mice, Inbred BALB C; Plants, Medicinal; Rauscher Virus; Spleen; Streptonigrin; Vincristine

1975
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine

1975
Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Binding Sites, Antibody; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Complement C3; Complement C4; Complement System Proteins; Dactinomycin; Doxorubicin; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Puromycin

1975
Character of the stimulatory response of uridine kinase in rat livers to cycloheximide treatment.
    European journal of biochemistry, 1975, Oct-01, Volume: 58, Issue:1

    Topics: Animals; Azacitidine; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Activation; Hydroxyurea; Kinetics; Liver; Male; Mitomycins; Phosphotransferases; Puromycin; Rats; Starvation; Uridine Kinase

1975
Induction of hepatic metallothionein following 5-azacytidine administration.
    Toxicology and applied pharmacology, 1985, Jun-15, Volume: 79, Issue:1

    Topics: Animals; Azacitidine; Cells, Cultured; Chromatography, Gel; Chromatography, Ion Exchange; Dactinomycin; Female; Gene Expression Regulation; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1985
Morphokinetic reaction of Streptococcus faecalis (ATCC 9790) cells to the specific inhibition of macromolecular synthesis: nucleoid condensation on the inhibition of protein synthesis.
    Journal of bacteriology, 1972, Volume: 109, Issue:3

    Topics: Anti-Bacterial Agents; Azacitidine; Bacterial Proteins; Carbon Isotopes; Cell Division; Cell Nucleus; Chloramphenicol; Culture Media; Dactinomycin; DNA Replication; DNA, Bacterial; Enterococcus faecalis; Genetic Code; Leucine; Macromolecular Substances; Microscopy, Electron; Mitomycins; Rifampin; RNA, Bacterial; Threonine; Thymidine; Tritium; Uracil

1972
Morphokinetic reaction of cells of Streptococcus faecalis (ATCC 9790) to specific inhibition of macromolecular synthesis: dependence of mesosome growth on deoxyribonucleic acid synthesis.
    Journal of bacteriology, 1972, Volume: 109, Issue:3

    Topics: Anti-Bacterial Agents; Azacitidine; Bacterial Proteins; Bacteriological Techniques; Carbon Isotopes; Cell Division; Cell Membrane; Chloramphenicol; Culture Media; Dactinomycin; DNA, Bacterial; Enterococcus faecalis; Glycerol; Leucine; Macromolecular Substances; Microscopy, Electron; Mitomycins; Rifampin; RNA, Bacterial; Spectrophotometry; Threonine; Thymidine; Tritium; Uracil

1972
Modified induction of ornithine decarboxylase by factors which affect liver regeneration.
    Biochimica et biophysica acta, 1972, Apr-12, Volume: 262, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Age Factors; Animals; Azacitidine; Azaguanine; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Hepatectomy; Hydrocortisone; Liver; Liver Neoplasms; Liver Regeneration; Male; Ornithine; Rats; Solubility

1972
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
    The Journal of biological chemistry, 1972, Sep-10, Volume: 247, Issue:17

    Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium

1972
Influence of macromolecular biosynthesis on cellular autolysis in Streptococcus faecalis.
    Journal of bacteriology, 1972, Volume: 112, Issue:1

    Topics: Alcohols; Autolysis; Azacitidine; Bacterial Proteins; Bacteriolysis; Benzene Derivatives; Carbon Isotopes; Chloramphenicol; Dactinomycin; DNA, Bacterial; Enterococcus faecalis; Leucine; Mitomycins; Puromycin; Rifampin; RNA, Bacterial; Tetracycline; Thymidine; Tritium; Uracil

1972
Enhanced uridine kinase in rat liver following 5-azacytidine administration. In vivo characterization and properties of partially purified enzyme.
    The Journal of biological chemistry, 1973, Feb-25, Volume: 248, Issue:4

    Topics: Adrenal Glands; Animals; Azacitidine; Cell-Free System; Cytidine; Dactinomycin; DNA; Dose-Response Relationship, Drug; Drug Stability; Injections, Intraperitoneal; Liver; Male; Nucleotidases; Phosphoric Monoester Hydrolases; Phosphotransferases; Protein Biosynthesis; Rats; RNA; Time Factors; Triazines; Uracil Nucleotides; Uridine

1973
Destructive processing of the 45-S ribosomal precursor in the presence of 5-azacytidine.
    Biochimica et biophysica acta, 1973, Feb-23, Volume: 299, Issue:1

    Topics: Azacitidine; Centrifugation, Density Gradient; Dactinomycin; HeLa Cells; Isotope Labeling; RNA, Ribosomal; Sodium Dodecyl Sulfate; Time Factors; Tritium

1973
Labeling of cytoplasmic liver RNA by (6- 14 C)orotic and 5-fluoro(2- 14 C)orotic acids. Effect of several inhibitors.
    European journal of biochemistry, 1973, Apr-02, Volume: 34, Issue:1

    Topics: Animals; Aza Compounds; Azacitidine; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cytoplasm; Dactinomycin; Fluorine; Liver; Male; Orotic Acid; Polyribosomes; Rats; RNA; RNA, Messenger; RNA, Ribosomal; Time Factors

1973
The mechanism of inhibition of protein synthesis by 5-azacytidine in HeLa cells.
    Biochimica et biophysica acta, 1973, Oct-12, Volume: 324, Issue:2

    Topics: Azacitidine; Carbon Radioisotopes; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Half-Life; HeLa Cells; Kinetics; Leucine; Neoplasm Proteins; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; RNA, Neoplasm; Tritium; Uridine

1973
Enhancement of rat liver uridine kinase activity by various metabolic inhibitors.
    Biochemical pharmacology, 1974, Mar-15, Volume: 23, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Azauridine; Carbon Radioisotopes; Cell-Free System; Cycloheximide; Dactinomycin; Daunorubicin; Diet; Doxorubicin; In Vitro Techniques; Liver; Male; Orotic Acid; Phosphotransferases; Puromycin; Pyrimidines; Rats; Stimulation, Chemical; Thioacetamide; Thymus Gland; Uridine

1974
Effect of inhibition of deoxyribonucleic acid and protein synthesis on the direction of cell wall growth in Streptococcus faecalis.
    Journal of bacteriology, 1974, Volume: 118, Issue:2

    Topics: Azacitidine; Bacterial Proteins; Carbon Radioisotopes; Cell Division; Cell Wall; Chloramphenicol; Chromosomes, Bacterial; Dactinomycin; DNA, Bacterial; Enterococcus faecalis; Microscopy, Electron; Mitomycins; Models, Biological; Peptidoglycan; Polysaccharides, Bacterial; Rifampin; RNA, Bacterial; Tritium

1974
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
    Archives of biochemistry and biophysics, 1974, Volume: 160, Issue:1

    Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine

1974
Effect of macromolecular synthesis and lytic capacity on surface growth of Streptococcus faecalis.
    Journal of bacteriology, 1980, Volume: 141, Issue:2

    Topics: Azacitidine; Bacterial Proteins; Cell Wall; Chloramphenicol; Dactinomycin; DNA, Bacterial; Enterococcus faecalis; Mitomycins; RNA, Bacterial

1980
Mechanism of 5-azacytidine-induced transfer RNA cytosine-5-methyltransferase deficiency.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: Animals; Azacitidine; Dactinomycin; Mice; Molecular Weight; RNA; tRNA Methyltransferases

1980
Regulation of de novo purine biosynthesis in Chinese hamster cells.
    The Journal of biological chemistry, 1982, Jan-10, Volume: 257, Issue:1

    Topics: Adenine; Amidophosphoribosyltransferase; Animals; Azacitidine; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cycloheximide; Dactinomycin; Female; Formates; Lung; Ovary; Purines; Ribonucleotides

1982
St. Louis encephalitis virus temperature-sensitive mutants. I. Induction, isolation and preliminary characterization.
    Archives of virology, 1983, Volume: 75, Issue:3

    Topics: Azacitidine; Dactinomycin; Encephalitis Virus, St. Louis; Flavivirus; Fluorouracil; Genetic Complementation Test; Hot Temperature; Methylnitronitrosoguanidine; Mutation; Phenotype; RNA, Viral

1983
Cytidine metabolism in photoreceptor cells of the rat.
    The Journal of cell biology, 1983, Volume: 97, Issue:3

    Topics: Animals; Autoradiography; Azacitidine; Cytidine; Cytidine Diphosphate Diglycerides; Dactinomycin; Light; Nucleoside Diphosphate Sugars; Phosphatidylinositols; Photoreceptor Cells; Rats; Retina; RNA

1983
dCMP-aminohydrolase activity during early sea urchin development. An example of negative enzyme control during embryogenesis.
    Experimental cell research, 1984, Volume: 152, Issue:1

    Topics: Animals; Azacitidine; Dactinomycin; DCMP Deaminase; DNA; Embryo, Nonmammalian; Female; Nucleotide Deaminases; Ovum; p-Fluorophenylalanine; Protein Biosynthesis; Puromycin; RNA; Sea Urchins; Thiouracil

1984
Regulation of de novo purine biosynthesis in Chinese hamster cells.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt A

    Topics: Amidophosphoribosyltransferase; Animals; Azacitidine; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Dactinomycin; Female; Kinetics; Lung; Ovary; Pentosyltransferases; Phosphotransferases; Purines; Ribose-Phosphate Pyrophosphokinase

1984
Hypertonicity induction of melanoma antigen, a tumor-associated antigen.
    Molecules and cells, 2002, Apr-30, Volume: 13, Issue:2

    Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Dactinomycin; Decitabine; Gene Expression Regulation; Humans; Hypertonic Solutions; Melanoma-Specific Antigens; Neoplasm Proteins; Protein Synthesis Inhibitors; RNA Stability; Sodium Chloride; Tumor Cells, Cultured; Up-Regulation

2002
Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors.
    Oxidative medicine and cellular longevity, 2011, Volume: 2011

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Butyrates; Caspase 3; Cell Line, Tumor; Cytostatic Agents; Dactinomycin; Decitabine; DNA Damage; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Vorinostat

2011
Epigenetic control of endothelin-1 axis affects invasiveness of breast carcinoma cells with bone tropism.
    Experimental cell research, 2013, Jul-15, Volume: 319, Issue:12

    Topics: Azacitidine; Bone Neoplasms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Collagen; Dactinomycin; DNA Methylation; Drug Combinations; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Laminin; Mutation; Neoplasm Invasiveness; Peptides, Cyclic; Proteoglycans; Proto-Oncogene Protein c-ets-1; Receptor, Endothelin A; RNA Stability; RNA, Messenger; Transcription, Genetic

2013
Global analysis of biogenesis, stability and sub-cellular localization of lncRNAs mapping to intragenic regions of the human genome.
    RNA biology, 2015, Volume: 12, Issue:8

    Topics: Alpha-Amanitin; Azacitidine; Cell Line, Tumor; Dactinomycin; Decitabine; DNA Modification Methylases; Gene Expression Profiling; Genome, Human; HeLa Cells; Humans; Introns; MCF-7 Cells; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA Polymerase II; RNA Stability; RNA, Antisense; RNA, Long Noncoding

2015