dactinomycin and ascorbic acid

dactinomycin has been researched along with ascorbic acid in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199031 (81.58)18.7374
1990's1 (2.63)18.2507
2000's2 (5.26)29.6817
2010's4 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cardinale, GJ; Kuttan, R; Stassen, FL; Udenfriend, S1
Datta, S; Sanyal, S1
Biswas, NM; Koley, AR1
Anderson, J; Nievel, JG; Skrbic, TR1
Degkwitz, E; Dubberstein, M; Walsch, S; Winter, J2
Banerjee, SK; Chatterjee, GC; Majumder, PK; Ray, B; Roy, RK; Rudrapal, D1
Artemenko, NK; Freidlin, IS; Lyzlova, SN; Nersesova, LS; Petrova, TA1
Bertram, JS1
Iwayama, Y1
Azzi, A; Wilson, DF1
MacDonald, RA; MacSween, RN; Pechet, GS1
Cardinale, GJ; Stassen, FL; Udenfriend, S1
Aarts, EM1
Kawada, S; Nakashima, Y; Sanada, H; Suzue, R1
Bader, M; Klinger, W; Thrum, H1
Artemenko, NK; Dzharak'ian, OT; Freĭdlin, IS1
Banerjee, SK; Chatterjee, GC; Majumder, PK; Roy, RK2
Seifert, J1
Nowosielski, J; Padzik, H; Paszko, Z; Pronaszko-Kurczyńska, A1
Nichol, AW1
Suzuki, Y; Takakuwa, S1
Hvitefelt, J; Santti, RS1
Jeffrey, JJ; Martin, GR1
Bublitz, C; Priest, RE1
Fouts, JR; Magus, RD1
Bukin, IuV; Levchuk, AA; Raushenbakh, MO; Rubtsov, IA; Smirnova, KD1
Chao, CC; Chiang, CD; Song, EJ; Yang, VC1
DEMATTEIS, F1
FUNAHASHI, S; SHICHI, H; SUGIMURA, Y1
De Gara, L; de Pinto, MC; Marra, E; Passarella, S; Vacca, RA; Valenti, D1
Lai, WL; Wong, NS1

Reviews

4 review(s) available for dactinomycin and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Relationships of protein and mineral intake to L-ascorbic acid metabolism, including considerations of some directly related hormones.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Adrenal Glands; Alcohol Oxidoreductases; Alloxan; Animals; Ascorbic Acid; Caseins; Dactinomycin; Diabetes Mellitus, Experimental; Diet; Dietary Proteins; Guinea Pigs; Hormones; Humans; Insulin; Liver; Metals; Phagocytosis; Pituitary Gland; Rats; RNA; Scurvy; Thyroid Gland

1975
Neoplastic transformation in cell cultures: in-vitro/in-vivo correlations.
    IARC scientific publications, 1985, Volume: 67

    Topics: Animals; Antigens, Neoplasm; Ascorbic Acid; Biotransformation; Calcium; Carcinogens; Cell Adhesion; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Dactinomycin; DNA; Glucocorticoids; Growth Substances; Mice; Neoplasms, Experimental; Oncogenes; Phorbol Esters; Protease Inhibitors; Retinoids; Saccharin; Structure-Activity Relationship

1985
Ascorbate stimulation of tyrosine hydroxylase formation.
    Nutrition reviews, 1973, Volume: 31, Issue:3

    Topics: Adrenal Glands; Animals; Ascorbic Acid; Dactinomycin; Guinea Pigs; Immunochemistry; Male; Precipitin Tests; Protein Biosynthesis; Puromycin; Rabbits; Scurvy; Time Factors; Tyrosine 3-Monooxygenase

1973

Other Studies

34 other study(ies) available for dactinomycin and ascorbic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Activation of prolyl hydroxylase in fibroblasts by ascorbic acid.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Ascorbic Acid; Cell Line; Cycloheximide; Dactinomycin; Dithiothreitol; Enzyme Activation; Fibroblasts; Lactates; Procollagen-Proline Dioxygenase; Puromycin

1975
Ascorbic acid depleting action of PGE1 in rat adrenal and ovary and the effect of cycloheximide and actinomycin D treatment.
    The Indian journal of medical research, 1979, Volume: 70

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Cycloheximide; Dactinomycin; Female; Ovary; Prostaglandins E; Rats

1979
Testicular delta5-3beta-hydroxysteroid dehydrogenase, ascorbic acid and dehydroascorbic acid in actinomycin D-treated toads.
    Experientia, 1978, Dec-15, Volume: 34, Issue:12

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Ascorbic Acid; Bufonidae; Dactinomycin; Dehydroascorbic Acid; Male; Testis

1978
Studies on the relationship between induction of drug-metabolizing enzymes, liver enlargement and ascorbic acid excretion in rodents.
    Biochemical Society transactions, 1976, Volume: 4, Issue:3

    Topics: Animals; Ascorbic Acid; Azauridine; Butylated Hydroxytoluene; Coumarins; Dactinomycin; Enzyme Induction; Female; Glucuronates; Hepatomegaly; Liver; Orotic Acid; Phenobarbital; Proadifen; Rats; Transcription, Genetic; Uracil; Uracil Nucleotides

1976
Ascorbic acid and cytochromes.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Adrenal Glands; Aminolevulinic Acid; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Collagen; Cycloheximide; Cytochrome P-450 Enzyme System; Cytochromes; Dactinomycin; Guinea Pigs; Iron; Kidney Cortex; Liver; Phenobarbital; Spleen

1975
[Changes in the functional activity of macrophages, their morphology and metabolism under the influence of several biologically active substances].
    Tsitologiia, 1975, Volume: 17, Issue:2

    Topics: Ascorbic Acid; Carbon Radioisotopes; Cathepsins; Chloramphenicol; Chloroquine; Creatine Kinase; Culture Techniques; Cycloheximide; Dactinomycin; Lipopolysaccharides; Lysine; Macrophages; Orotic Acid; Peritoneum; Phagocytosis; Protein Biosynthesis; Puromycin; Rifampin; RNA; Tetracycline; Uridine

1975
[Collagen biosynthesis in gingival tissues of guinea pig].
    [Osaka Daigaku shigaku zasshi] The journal of Osaka University Dental Society, 1966, Volume: 11, Issue:1

    Topics: Ascorbic Acid; Collagen; Dactinomycin; Dentistry; Gingiva; Puromycin

1966
Stoichiometry and site specificity of uncouplers of mitochondrial oxidative phosphorylation.
    Archives of biochemistry and biophysics, 1968, Volume: 126, Issue:2

    Topics: Adenosine Triphosphatases; Anilides; Animals; Ascorbic Acid; Dactinomycin; Energy Transfer; Glutamates; Malates; Mitochondria, Liver; Oxidative Phosphorylation; Rats; Rotenone; Succinates

1968
Iron metabolism by reticuloendothelial cells in vitro. Physical and chemical conditions, lipotrope deficiency, and acute inflammation.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:3

    Topics: Animals; Ascorbic Acid; Cobalt; Copper; Cysteine; Dactinomycin; Deferoxamine; Dinitrophenols; Edetic Acid; Fatty Liver; Fluorides; Fructose; Glucose; Glutathione; Hemochromatosis; Inflammation; Iodoacetates; Iron; Lipotropic Agents; Liver Cirrhosis; Lung; Macrophages; Microscopy, Electron; Potassium Permanganate; Protein Biosynthesis; Puromycin; Rabbits; RNA; Saponins; Sucrose; Surface-Active Agents; Transferrin; Trypsin

1969
Activation of prolyl hydroxylase in L-929 fibroblasts by ascorbic acid.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:4

    Topics: Animals; Ascorbic Acid; Cell Division; Cell Line; Chromatography, Ion Exchange; Cycloheximide; Dactinomycin; Dithiothreitol; Enzyme Activation; Fibroblasts; Immunoassay; Lactates; Mice; Mixed Function Oxygenases; Procollagen-Proline Dioxygenase; Puromycin; Time Factors

1973
Differentiation of the barbiturate stimulation of the glucuronic acid pathway from de novo enzyme synthesis.
    Biochemical pharmacology, 1966, Volume: 15, Issue:10

    Topics: Alcohol Oxidoreductases; Alkylation; Animals; Ascorbic Acid; Barbiturates; Chlorobutanol; Dactinomycin; Female; Glucuronates; Guinea Pigs; Liver; Microsomes; Monosaccharides; Puromycin; Rats; Silicon Dioxide; Transaminases; Tyrosine Transaminase

1966
Effect of ascorbic acid on tyrosine hydroxylase activity in vivo.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Adrenal Glands; Ammonium Sulfate; Animals; Ascorbic Acid; Chemical Precipitation; Chromatography; Chromatography, Gel; Cytoplasm; Dactinomycin; Dialysis; Enzyme Induction; Guinea Pigs; Hydroxyapatites; Male; Precipitin Tests; Puromycin; Rabbits; Scurvy; Tyrosine 3-Monooxygenase

1972
Actinomycin D: influence on induction of liver microsomal enzymes.
    Acta biologica et medica Germanica, 1974, Volume: 32, Issue:1

    Topics: Aminopyrine N-Demethylase; Ascorbic Acid; Dactinomycin; Drug Interactions; Enzyme Induction; Hexobarbital; Microsomes, Liver; Sleep

1974
[Effect of some biologically active substances on the intensity of the cleansing of bacteriophage T2 particles from the blood channel in mice].
    Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1974, Issue:9

    Topics: Animals; Ascorbic Acid; Blood Bactericidal Activity; Chloramphenicol; Chloroquine; Coliphages; Dactinomycin; Depression, Chemical; Histones; Lectins; Lipopolysaccharides; Mice; Olivomycins; Phagocytosis; Protein Biosynthesis; Rifamycins; Stimulation, Chemical; Tetracycline; Time Factors; Transcription, Genetic

1974
Effect of insulin on the metabolism of L-ascorbic acid in animals.
    Biochemical pharmacology, 1973, Mar-15, Volume: 22, Issue:6

    Topics: Alcohol Oxidoreductases; Animals; Ascorbic Acid; Cycloheximide; Dactinomycin; Diabetes Mellitus, Experimental; Esterases; Insulin; Kidney; Lactones; Liver; Male; Rats

1973
Effect of hydrocortisone on the metabolism of L-ascorbic acid in rats.
    Biochemical pharmacology, 1973, Aug-01, Volume: 22, Issue:15

    Topics: Adrenal Glands; Adrenalectomy; Animals; Ascorbic Acid; Dactinomycin; Hydrocortisone; Kidney; Lactones; Liver; Male; Oxidoreductases; Rats; Spleen

1973
Tryptophan pyrrolase in rat liver after phenobarbital administration.
    Toxicology, 1973, Volume: 1, Issue:3

    Topics: Animals; Ascorbic Acid; Dactinomycin; Enzyme Activation; Enzyme Induction; Heme; Hydrocortisone; Liver; Male; Phenobarbital; Proteins; Rats; Time Factors; Tryptophan; Tryptophan Oxygenase

1973
The effect of actinomycin D on nucleic acid, protein, and lipid synthesis and contents of ascorbic acid and cholesterol influenced by LH in the luteinized rat ovary.
    Archivum immunologiae et therapiae experimentalis, 1973, Volume: 21, Issue:5

    Topics: Animals; Anticholesteremic Agents; Ascorbic Acid; Cholesterol; Dactinomycin; Depression, Chemical; DNA; Drug Synergism; Female; Lipids; Luteinizing Hormone; Ovary; Protein Biosynthesis; Rats; RNA; Time Factors

1973
Influence of L-ascorbate on the contents of cytochromes P-450 and b5 in several organs of guinea pigs.
    Enzyme, 1973, Volume: 16, Issue:1

    Topics: Adrenal Glands; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Cytochrome P-450 Enzyme System; Cytochromes; Dactinomycin; Ferritins; Gluconates; Guinea Pigs; Iron; Kidney; Levulinic Acids; Liver; Microsomes; Microsomes, Liver; Mitochondria, Liver; Organ Specificity; Phenobarbital; Spleen; Time Factors

1973
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
    Biochimica et biophysica acta, 1970, Oct-27, Volume: 222, Issue:1

    Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles

1970
Ascorbate oxidase formation in the cucumber seedling.
    Enzymologia, 1971, Sep-30, Volume: 41, Issue:3

    Topics: Ascorbic Acid; Carbamates; Catechol Oxidase; Chloramphenicol; Cycloheximide; Dactinomycin; Depression, Chemical; Disulfides; Ethionine; Formates; Manometry; Phenylthiourea; Plant Development; Plants; Purines; Sodium; Sulfhydryl Compounds

1971
Tryptophan pyrrolase in the liver of guinea pig: the absence of hydrocortisone induction.
    Biochimica et biophysica acta, 1972, Feb-28, Volume: 258, Issue:2

    Topics: Animals; Ascorbic Acid; Dactinomycin; Enzyme Induction; Female; Guinea Pigs; Hydrocortisone; Liver; Male; Oxidation-Reduction; Prednisolone; RNA; Solubility; Thymus Gland; Time Factors; Tritium; Tryptophan; Tryptophan Oxygenase; Uridine

1972
The role of ascorbic acid in the biosynthesis of collagen. II. Site and nature of ascorbic acid participation.
    Biochimica et biophysica acta, 1966, Jun-29, Volume: 121, Issue:2

    Topics: Animals; Ascorbic Acid; Bone and Bones; Chick Embryo; Collagen; Culture Techniques; Dactinomycin; DNA; Hydroxyproline; RNA; Tibia; Uridine

1966
The influence of ascorbic acid and tetrahydropteridine on the synthesis of hydroxyproline by cultured cells.
    Laboratory investigation; a journal of technical methods and pathology, 1967, Volume: 17, Issue:4

    Topics: Animals; Ascorbic Acid; Carbon Isotopes; Culture Media; Culture Techniques; Dactinomycin; Folic Acid; Hydroxyproline; Mercaptoethanol; Mice; Mitosis; Pteridines; RNA; RNA, Messenger

1967
Multiple action of 2'-diethylaminoethyl 2,2-diphenylpentanoate HCl (SKF 525-A) on rat liver tryptophan pyrrolase in vivo.
    Biochemical pharmacology, 1967, Jul-07, Volume: 16, Issue:7

    Topics: Adrenal Glands; Adrenalectomy; Animals; Ascorbic Acid; Cycloheximide; Dactinomycin; Enzyme Induction; Hydrocortisone; Hypophysectomy; Liver; Male; Proadifen; Puromycin; Rats; Spectrophotometry; Tryptophan Oxygenase

1967
[Effect of L-ascorbic and D-isoascorbic acids on induced formation of tyrosine aminotransferase in rat liver].
    Voprosy meditsinskoi khimii, 1981, Volume: 27, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Animals; Ascorbic Acid; Dactinomycin; Enzyme Induction; Hydrocortisone; Liver; Male; Rats; Rats, Inbred Strains; Tyrosine Transaminase

1981
Ascorbic acid increases drug accumulation and reverses vincristine resistance of human non-small-cell lung-cancer cells.
    The Biochemical journal, 1994, Aug-01, Volume: 301 ( Pt 3)

    Topics: Ascorbic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cisplatin; Colchicine; Dactinomycin; Doxorubicin; Drug Resistance; Gene Expression; Humans; Lung Neoplasms; Membrane Glycoproteins; Tumor Cells, Cultured; Vinblastine; Vincristine

1994
INCREASED SYNTHESIS OF L-ASCORBIC ACID CAUSED BY DRUGS WHICH INDUCE PORPHYRIA.
    Biochimica et biophysica acta, 1964, Mar-16, Volume: 82

    Topics: Acetates; Amides; Ascorbic Acid; Barbiturates; Chlorobutanol; Dactinomycin; Ethionine; Fluorescence; Glucose; Hexachlorocyclohexane; Hypnotics and Sedatives; Metabolism; Oxidoreductases; Pharmacology; Porphyrias; Pyridines; Rats; Research; Sulfones; Urine

1964
HAEMPROTEINS IN HEART MICROSOMES. II. A POSSIBLE ROLE FOR HAEMPROTEOLIPID IN HAEMPROTEIN BIOSYNTHESIS.
    Biochimica et biophysica acta, 1965, Mar-08, Volume: 97

    Topics: Ascorbic Acid; Chloramphenicol; Dactinomycin; Heme; Hemeproteins; Iron; Iron Isotopes; Microsomes; Myocardium; NAD; Pharmacology; Phenylalanine; Porphyrins; Proteins; Research; Surface-Active Agents

1965
Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco Bright-Yellow 2 cells.
    Plant physiology, 2004, Volume: 134, Issue:3

    Topics: Apoptosis; Ascorbate Peroxidases; Ascorbic Acid; Base Sequence; Cell Line; Cycloheximide; Cytosol; Dactinomycin; DNA, Plant; Energy Metabolism; Free Radical Scavengers; Heat-Shock Response; Kinetics; Mitochondria; Nicotiana; Peroxidases; Reactive Oxygen Species; RNA, Messenger; RNA, Plant

2004
ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene.
    Free radical biology & medicine, 2005, Jun-15, Volume: 38, Issue:12

    Topics: Antioxidants; Ascorbic Acid; CCAAT-Enhancer-Binding Proteins; Dactinomycin; Fenretinide; Flavanones; HeLa Cells; HT29 Cells; Humans; Lipoxygenase Inhibitors; Promoter Regions, Genetic; Reactive Oxygen Species; RNA, Messenger; Transcription Factor CHOP; Transcription Factors; Transcription, Genetic; Umbelliferones

2005