dactinomycin has been researched along with amsacrine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 8 (36.36) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denny, WA; Feigon, J; Kearns, DR; Leupin, W | 1 |
| Bu, X; Eleftheriou, A; Hayek, C; Parmar, A; Stewart, BW; Wakelin, LP | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Bu, X; Eleftheriou, A; He, Z; Qing, Z; Stewart, BW; Wakelin, LP; Zihlif, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| DeMarini, DM; Lawrence, BK | 2 |
| Leblanc, J; Sikorska, M; Smith, C; Walker, PR; Whitfield, JF; Youdale, T | 1 |
| Doerr, CL; Harrington-Brock, K; Moore, MM | 1 |
| Davies, SL; Davies, SM; Harris, AL; Hickson, ID | 1 |
| Ganapathi, R; Grabowski, D; Israel, M; Schmidt, H; Seshadri, R | 1 |
| Bleumink, AR; Jensen, CG; Wilson, WR | 1 |
| Hanauske, AR; Von Hoff, DD | 1 |
| Kleinerman, ES; Muchmore, AV; Schwartz, R; Zwelling, LA | 1 |
| Behrens, CH; Behrens, DL; Chen, SF; Fredericks, JR; Kirshenbaum, MR; Papp, LM; Polkus, ST; Sipple, P; Stafford, MM; Sun, JH | 1 |
| Cortés, F; López Baena, M; Ortiz, T; Piñero, J | 1 |
| Aplan, PD; Chervinsky, DS; Stanulla, M; Wang, J | 1 |
| Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R | 1 |
| Phan, TN; Tuteja, N | 1 |
| Carabillò, M; Giuliano, M; Lauricella, M; Tesoriere, G; Vassallo, E; Vento, R | 1 |
| Graves, DE | 1 |
1 review(s) available for dactinomycin and amsacrine
| Article | Year |
|---|---|
Clinical correlations with the human tumor cloning assay.
Topics: Aminoacridines; Amsacrine; Anthracenes; Breast Neoplasms; Clinical Trials as Topic; Clone Cells; Culture Techniques; Dactinomycin; Drug Resistance; Female; Head and Neck Neoplasms; Humans; Interferon Type I; Leukemia; Lung Neoplasms; Melanoma; Multiple Myeloma; Neoplasms; Ovarian Neoplasms; Prospective Studies; Retrospective Studies; Tumor Stem Cell Assay | 1985 |
1 trial(s) available for dactinomycin and amsacrine
| Article | Year |
|---|---|
Clinical correlations with the human tumor cloning assay.
Topics: Aminoacridines; Amsacrine; Anthracenes; Breast Neoplasms; Clinical Trials as Topic; Clone Cells; Culture Techniques; Dactinomycin; Drug Resistance; Female; Head and Neck Neoplasms; Humans; Interferon Type I; Leukemia; Lung Neoplasms; Melanoma; Multiple Myeloma; Neoplasms; Ovarian Neoplasms; Prospective Studies; Retrospective Studies; Tumor Stem Cell Assay | 1985 |
21 other study(ies) available for dactinomycin and amsacrine
| Article | Year |
|---|---|
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 1984 |
Bisintercalating threading diacridines: relationships between DNA binding, cytotoxicity, and cell cycle arrest.
Topics: Acridines; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; DNA; DNA, Superhelical; Electrophoresis, Agar Gel; Flow Cytometry; G2 Phase; Guanine; Humans; Hydrogen Bonding; Intercalating Agents; Kinetics; Mitosis; Structure-Activity Relationship | 2003 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
DNA threading bis(9-aminoacridine-4-carboxamides): effects of piperidine sidechains on DNA binding, cytotoxicity and cell cycle arrest.
Topics: Aminoacridines; Cell Cycle; Cell Line, Tumor; Dimerization; DNA; Humans; Molecular Structure; Piperidines; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Prophage induction by DNA topoisomerase II poisons and reactive-oxygen species: role of DNA breaks.
Topics: Amsacrine; Azides; Bacteriophage lambda; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Escherichia coli; Free Radicals; Hydrogen Peroxide; Lysogeny; Nalidixic Acid; Novobiocin; Oxolinic Acid; Oxygen; Paraquat; Sodium Azide; SOS Response, Genetics; Teniposide; Topoisomerase II Inhibitors; Virus Replication | 1992 |
Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.
Topics: Amsacrine; Animals; Cycloheximide; Dactinomycin; Dexamethasone; DNA; Electrophoresis; Etoposide; Flow Cytometry; Lymphocytes; Mitosis; Rats; Rats, Inbred Strains; Teniposide; Thymus Gland; Time Factors; Topoisomerase II Inhibitors | 1991 |
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoacridines; Amsacrine; Animals; Bleomycin; Chromosome Aberrations; Dactinomycin; Dimethyl Sulfoxide; DNA Damage; Doxorubicin; Hazardous Waste; Leukemia L5178; Leukemia, Experimental; Methylcholanthrene; Methylmethacrylate; Methylmethacrylates; Mice; Micronucleus Tests; Mutation; Nitrogen Mustard Compounds; Proflavine; Thymidine Kinase | 1989 |
Isolation of two Chinese hamster ovary cell mutants hypersensitive to topoisomerase II inhibitors and cross-resistant to peroxides.
Topics: Amsacrine; Animals; Cell Line; Cell Survival; Cricetinae; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Female; Mitoxantrone; Mutation; Ovary; Teniposide; Topoisomerase II Inhibitors | 1989 |
Mutagenicity of topoisomerase-active agents in bacteriophage T4.
Topics: Amsacrine; Dactinomycin; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Mutation; Nalidixic Acid; Novobiocin; Oxolinic Acid; T-Phages | 1988 |
Calmodulin inhibitor trifluoperazine selectively enhances cytotoxic effects of strong vs weak DNA binding antitumor drugs in doxorubicin-resistant P388 mouse leukemia cells.
Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Dactinomycin; Daunorubicin; DNA; Doxorubicin; Drug Interactions; Drug Resistance; Leukemia P388; Leukemia, Experimental; Menogaril; Mice; Mitoxantrone; Naphthacenes; Nogalamycin; Trifluoperazine | 1985 |
Effects of amsacrine and other DNA-intercalating drugs on nuclear and nucleolar structure in cultured V79 Chinese hamster cells and PtK2 rat kangaroo cells.
Topics: Aminacrine; Aminoacridines; Amsacrine; Animals; Anthraquinones; Cell Nucleolus; Cell Nucleus; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Dactinomycin; Dipodomys; Doxorubicin; Fibroblasts; Intercalating Agents; Kidney; Microscopy, Electron; Mitoxantrone | 1985 |
Effect of L-phenylalanine mustard, adriamycin, actinomycin D, and 4'-(9-acridinylamino)methanesulfon-m-anisidide on naturally occurring human spontaneous monocyte-mediated cytotoxicity.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cisplatin; Cytotoxicity, Immunologic; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Humans; Immunity, Innate; In Vitro Techniques; Lymphocytes; Melphalan; Monocytes | 1982 |
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Isoquinolines; KB Cells; Kinetics; Leucine; Leukemia L1210; Leukemia P388; Mammary Neoplasms, Experimental; Melanoma; Melanoma, Experimental; Mesylates; Mice; Mitoxantrone; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured; Uridine | 1994 |
Sister chromatid exchange induced by DNA topoisomerases poisons in late replicating heterochromatin: influence of inhibition of replication and transcription.
Topics: Amsacrine; Animals; Aphidicolin; Camptothecin; CHO Cells; Chromatin; Cricetinae; Dactinomycin; DNA Replication; Enzyme Inhibitors; Euchromatin; Heterochromatin; Isomerases; Sister Chromatid Exchange; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic | 1996 |
Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus.
Topics: Amsacrine; Antineoplastic Agents; Base Sequence; Cell Line; Dactinomycin; DNA Damage; DNA, Neoplasm; Doxorubicin; Etoposide; Genes, abl; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Monocytes; Restriction Mapping; Topoisomerase II Inhibitors; Translocation, Genetic | 1997 |
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors | 1997 |
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum | 1998 |
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors.
Topics: Amsacrine; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dactinomycin; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Insulin-Like Growth Factor Binding Protein 3; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Targeting DNA through-covalent interactions of reversible binding drugs.
Topics: Amsacrine; Base Sequence; Binding Sites; Dactinomycin; DNA; DNA Topoisomerases, Type II; Drug Design; Ethidium; In Vitro Techniques; Intercalating Agents; Ligands; Models, Molecular; Nucleic Acid Conformation; Pharmaceutical Preparations; Photochemistry | 2001 |