dactinomycin and alprostadil

dactinomycin has been researched along with alprostadil in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's4 (28.57)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Fukui, H; Kikuchi, E; Kitano, H; Matsumoto, M; Morimura, M; Nakano, H; Okamoto, Y; Tsujii, T1
Abdel-Malek, ZA; Amornsiripanitch, N; Nordlund, JJ; Swope, VB1
Lin, JX; Vilcek, J; Zhang, Y1
Hakeda, Y; Hiramatsu, M; Ikeda, E; Kumegawa, M; Kurihara, N; Nakatani, Y; Tsunoi, M1
Forray, C; Richelson, E1
Higashida, H; Kato, K; Sano, M1
Lamberts, SW; Oosterom, R; Verleun, T; Zuiderwijk, J1
Endo, N; Harada, S; Nagy, JA; Rodan, GA; Rodan, SB; Sullivan, KA; Thomas, KA1
An, S; Goetzl, EJ; Zeng, L1
Fang, GD; Guerrant, RL; Marcinkiewicz, M; Sarosiek, J; Thielman, NM1

Other Studies

14 other study(ies) available for dactinomycin and alprostadil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
D-galactosamine-induced cell damage enhances specific binding of prostaglandin E1 to rat hepatocytes.
    Biochemical and biophysical research communications, 1992, Apr-30, Volume: 184, Issue:2

    Topics: Alprostadil; Animals; Binding Sites; Binding, Competitive; Carbon Tetrachloride; Cells, Cultured; Cycloheximide; Dactinomycin; Galactosamine; Glucagon; Kinetics; Linoleic Acid; Linoleic Acids; Liver; Male; Norepinephrine; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Prostaglandin E

1992
In vitro modulation of proliferation and melanization of S91 melanoma cells by prostaglandins.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Bucladesine; Cell Division; Cycloheximide; Dactinomycin; Dinoprostone; In Vitro Techniques; Melanins; Melanoma; Monophenol Monooxygenase; Prostaglandin D2; Prostaglandins; Prostaglandins A; Prostaglandins D; Prostaglandins E

1987
Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP.
    The Journal of biological chemistry, 1988, May-05, Volume: 263, Issue:13

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Bucladesine; Cholera Toxin; Cyclic AMP; Dactinomycin; Enzyme Activation; Fibroblasts; Humans; Interleukin-6; Interleukins; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Inductive effects of prostaglandins on alkaline phosphatase in osteoblastic cells, clone MC3T3-E1.
    Journal of biochemistry, 1985, Volume: 97, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Alprostadil; Animals; Bone and Bones; Cell Line; Clone Cells; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Induction; Mice; Osteoblasts; Prostaglandins; Prostaglandins E; Prostaglandins F

1985
Glucocorticoids potentiate the prostaglandin E1-mediated cyclic AMP formation by a cultured murine neuroblastoma clone.
    Journal of neurochemistry, 1985, Volume: 45, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Corticosterone; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Drug Synergism; Glucocorticoids; Indomethacin; Kinetics; Mice; Neuroblastoma; Prostaglandins E

1985
Forskolin induction of S-100 protein in glioma and hybrid cells.
    Journal of cellular physiology, 1985, Volume: 122, Issue:1

    Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Colforsin; Cycloheximide; Dactinomycin; Diterpenes; Glioma; Hybrid Cells; Isoproterenol; Kinetics; Mice; Neuroblastoma; Prostaglandins E; Rats; S100 Proteins; Theophylline

1985
Growth hormone secretion by cultured rat anterior pituitary cells. Effects of culture conditions and dexamethasone.
    Endocrinology, 1983, Volume: 113, Issue:2

    Topics: Alprostadil; Animals; Cells, Cultured; Culture Media; Dactinomycin; Dexamethasone; Dopamine; Female; Growth Hormone; Kinetics; Pituitary Gland, Anterior; Prolactin; Prostaglandins E; Rats; Rats, Inbred Strains; Somatostatin; Theophylline

1983
Induction of vascular endothelial growth factor expression by prostaglandin E2 and E1 in osteoblasts.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:6

    Topics: Alprostadil; Animals; Base Sequence; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Endothelial Growth Factors; Female; Lymphokines; Molecular Sequence Data; Osteoblasts; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tibia; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1994
Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP3 subtype of prostaglandin E2 receptor.
    The Journal of biological chemistry, 1996, Nov-01, Volume: 271, Issue:44

    Topics: Adenine; Alprostadil; Blotting, Northern; Bucladesine; Calcium; Cell Line; Colforsin; Collagenases; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, T-Cell; Matrix Metalloproteinase 9; Misoprostol; Prostaglandins E, Synthetic; Receptors, Prostaglandin E; RNA, Messenger; T-Lymphocytes; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured

1996
Role of platelet-activating factor in Chinese hamster ovary cell responses to cholera toxin.
    The Journal of clinical investigation, 1997, Apr-15, Volume: 99, Issue:8

    Topics: Alprostadil; Animals; Bucladesine; Cell Size; CHO Cells; Cholera Toxin; Cricetinae; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Diterpenes; Ginkgolides; Humans; Lactones; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles

1997