dactinomycin has been researched along with allopurinol in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (40.63) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Badawy, AA; Evans, M | 2 |
| Frydman, J; Frydman, RB; Tomaro, ML | 1 |
| Moochhala, SM; Renton, KW | 1 |
| Heintz, NH; Janssen, YM; Manohar, M; Marsh, JP; Mossman, BT; Periasamy, M; Shull, S | 1 |
| Dozono, H; Ishibashi, M; Miwa, K; Motoya, T; Nagata, Y; Nakamura, K; Nakamura, S; Shinmura, R | 1 |
| Bergevin, PR; Blom, J; Tormey, DC | 1 |
| Greengard, O; Thorndike, J | 1 |
| Wyngaarden, JB | 1 |
| Cangir, A; Sullivan, MP; Sutow, WW; Taylor, G | 1 |
| Dekker, CA; Holloman, WK | 1 |
| Fischer, DS | 1 |
| Spadoni, MA; Ticca, M | 1 |
| Rowe, PB; Wyngaarden, JB | 1 |
| Kazura, JW; Reiner, NE | 1 |
| Badawy, AA | 1 |
| Fanburg, BL; Hassoun, PM; Lanzillo, JJ; Shedd, AL; Thannickal, VJ; Yu, FS; Zulueta, JJ | 1 |
| Fanburg, BL; Thannickal, VJ | 1 |
| Chen, F; Demers, LM; Gaydos, LJ; Kuhn, DC | 1 |
| Garcia, I; Maier, RV; Mendez, C | 1 |
| Garattini, E; Kurosaki, M; Li Calzi, M; Terao, M; Zanotta, S | 1 |
| Gabriel, A; Gandhi, CR; Kuddus, RH; Rao, AS; Watkins, WD | 1 |
| Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N | 1 |
| Becker, I; Giffhorn-Katz, S; Immenschuh, S; Katz, N; Ohlmann, A | 1 |
| Kim, PH; Lee, WH; Lee, YW | 1 |
| Andriantsitohaina, R; Freyssinet, JM; MartÃnez, MC; Mostefai, HA; Rottner, M; Tual-Chalot, S | 1 |
4 review(s) available for dactinomycin and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Guide to the use of cancer chemotherapeutic agents.
Topics: Alkylating Agents; Allopurinol; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Asparaginase; Azaserine; Azauridine; Bleomycin; Camptothecin; Carmustine; Cell Division; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Fluorouracil; Humans; Kinetics; Neoplasms; Nitrogen Mustard Compounds; Procarbazine; Triazines; Vincristine | 1972 |
Changing enzyme patterns in chick organs during development.
Topics: Aging; Animals; Brain; Chick Embryo; Chickens; Dactinomycin; Energy Metabolism; Enzymes; Fructose-Bisphosphate Aldolase; Glycogen Synthase; Guinea Pigs; Hormones; Isoenzymes; Kidney; Liver; Myocardium; Nitrogen; Nutritional Physiological Phenomena; Pyruvate Kinase; Rats; RNA; Xanthine Oxidase | 1974 |
The use of drugs in various types of cancer. 1.
Topics: Allopurinol; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Cyclophosphamide; Dactinomycin; Diethylstilbestrol | 1970 |
1 trial(s) available for dactinomycin and allopurinol
| Article | Year |
|---|---|
[Prevention of stomatitis induced by anti-cancer drugs].
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Mouth Mucosa; Mouthwashes; Random Allocation; Stomatitis; Vincristine | 1989 |
27 other study(ies) available for dactinomycin and allopurinol
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Animal liver tryptophan pyrrolases: Absence of apoenzyme and of hormonal induction mechanism from species sensitive to tryptophan toxicity.
Topics: Allopurinol; Animals; Apoenzymes; Cats; Cattle; Cricetinae; Cycloheximide; Dactinomycin; Enzyme Induction; Gerbillinae; Guinea Pigs; Hydrocortisone; Liver; Mice; Poultry; Rabbits; Rats; Sheep; Swine; Tryptophan; Tryptophan Oxygenase | 1976 |
Heme oxygenase induction by CoCl2, Co-protoporphyrin IX, phenylhydrazine, and diamide: evidence for oxidative stress involvement.
Topics: Allopurinol; Animals; Antioxidants; Cobalt; Cycloheximide; Dactinomycin; Diamide; Enzyme Induction; Female; Heme Oxygenase (Decyclizing); Kinetics; Liver; Phenylhydrazines; Protoporphyrins; Rats; Rats, Inbred Strains; Vitamin E | 1991 |
A role for xanthine oxidase in the loss of cytochrome P-450 evoked by interferon.
Topics: Allopurinol; Aminopyrine N-Demethylase; Animals; Biotransformation; Concanavalin A; Cricetinae; Cytochrome P-450 Enzyme System; Dactinomycin; Enzyme Induction; Hypoxanthines; In Vitro Techniques; Interferon Type I; Interferons; Male; Mesocricetus; Microsomes, Liver; Poly I-C; Recombinant Proteins; Vitamin E; Xanthine Oxidase | 1991 |
Differential regulation of antioxidant enzymes in response to oxidants.
Topics: Animals; Blotting, Northern; Blotting, Western; Catalase; Cell Cycle; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Glutathione Peroxidase; Humans; RNA, Messenger; Superoxide Dismutase; Trachea; Xanthine Oxidase | 1991 |
Genetic control of enzyme activity in higher organisms.
Topics: Animals; Arginase; Cell Differentiation; Dactinomycin; Dexamethasone; Diet; Enzyme Induction; Enzyme Repression; Enzymes; Feedback; Fluorouracil; Genes; Genetic Code; Gluconeogenesis; Liver; Molecular Biology; Protein Biosynthesis; Puromycin; Rabbits; RNA; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase; Xanthine Oxidase | 1970 |
Vincristine sulfate in management of Wilms' tumor. Replacement of preoperative irradiation by chemotherapy.
Topics: Allopurinol; Child; Child, Preschool; Dactinomycin; Female; Humans; Lung Neoplasms; Male; Neoplasm Metastasis; Nephrectomy; Preoperative Care; Sulfates; Vincristine; Wilms Tumor | 1967 |
Guinea-pig liver tryptophan pyrrolase. Absence of detectable apoenzyme activity and of hormonal induction by cortisol and possible regulation by tryptophan.
Topics: Aging; Allopurinol; Animals; Apoproteins; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Precursors; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; Male; Rats; Tryptophan; Tryptophan Oxygenase | 1974 |
Control by cesium and intermediates of the citric acid cycle of extracellular ribonuclease and other enzymes involved in the assimilation of nitrogen.
Topics: Ammonia; Cesium; Chlorides; Citrates; Citric Acid Cycle; Cycloheximide; Dactinomycin; Enzyme Induction; Fumarates; Fungi; Galactosidases; Glutarates; Histidine; Lyases; Malates; Mercaptopurine; Methylamines; Nitrates; Nitrogen; Oxaloacetates; Oxidoreductases; Phenylalanine; Ribonucleases; Succinates; Sucrase; Xanthine Oxidase | 1971 |
Effect of the administration of xanthine on the appearance of xanthine oxidase activity in the liver of growing rats.
Topics: Aging; Animals; Carbon Isotopes; Cortisone; Cycloheximide; Dactinomycin; Leucine; Liver; Orotic Acid; Phenylalanine; Rats; RNA; Xanthine Oxidase; Xanthines | 1968 |
The mechanism of dietary alterations in rat hepatic xanthine oxidase levels.
Topics: Animals; Dactinomycin; Dietary Proteins; Fluorouracil; In Vitro Techniques; Leucine; Liver; Orotic Acid; Puromycin; Rats; RNA; Xanthine Oxidase | 1966 |
Oxidant-mediated damage of Leishmania donovani promastigotes.
Topics: Acetaldehyde; Animals; Cycloheximide; Dactinomycin; Leishmania; Oxidation-Reduction; Oxygen; Peroxides; Puromycin; Superoxides; Xanthine Oxidase | 1982 |
Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.
Topics: Allopurinol; Animals; Corticosterone; Dactinomycin; Glucose; Liver; Male; NAD; NADP; Propranolol; Rats; Starvation; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase | 1981 |
Regulation of endothelial cell xanthine dehydrogenase xanthine oxidase gene expression by oxygen tension.
Topics: Adipose Tissue; Animals; Base Sequence; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Epididymis; Gene Expression; Intracellular Membranes; Male; Molecular Probes; Molecular Sequence Data; Osmolar Concentration; Oxygen; RNA, Messenger; Swine; Xanthine Dehydrogenase; Xanthine Oxidase | 1994 |
Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1.
Topics: Animals; Arginine; Cell Line; Cycloheximide; Dactinomycin; Electron Transport; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Hydrogen Peroxide; Interleukin-1; Kinetics; Lung; Microsomes; Mitochondria; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Swine; Time Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1995 |
Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA-primed THP-1 cells.
Topics: Allopurinol; Antimetabolites; Arginine; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Humans; Leukemia, Monocytic, Acute; Lipopolysaccharides; Monocytes; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Synthesis Inhibitors; RNA, Messenger; Silicon Dioxide; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthine Oxidase | 1996 |
Oxidants augment endotoxin-induced activation of alveolar macrophages.
Topics: Animals; Blood Coagulation Factors; Cells, Cultured; CHO Cells; Cricetinae; Dactinomycin; Diamide; Electrophoresis; Endotoxins; Glucose Oxidase; Glutathione; Humans; Infant, Newborn; Macrophages, Alveolar; Male; Multiple Organ Failure; NF-kappa B; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Synthesis Inhibitors; Rabbits; Reactive Oxygen Species; Respiratory Distress Syndrome, Newborn; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1996 |
Expression of xanthine oxidoreductase in mouse mammary epithelium during pregnancy and lactation: regulation of gene expression by glucocorticoids and prolactin.
Topics: Animals; Cycloheximide; Dactinomycin; Dexamethasone; Epithelium; Female; Gene Expression Regulation, Enzymologic; Genistein; In Situ Hybridization; Isoflavones; Lactation; Mammary Glands, Animal; Mice; Mice, Inbred Strains; Mifepristone; Pregnancy; Pregnancy, Animal; Prolactin; RNA, Messenger; Time Factors; Transcription, Genetic; Vanadates; Xanthine Oxidase | 1996 |
Superoxide-induced changes in endothelin (ET) receptors in hepatic stellate cells.
Topics: Adipocytes; Animals; Arachidonic Acid; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelin-1; Liver; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Superoxides; Xanthine Oxidase | 1998 |
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Edetic Acid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Neutrophils; Nitrates; Protein Biosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Xanthine Oxidase | 1999 |
Regulation of heme oxygenase-1 gene expression by anoxia and reoxygenation in primary rat hepatocyte cultures.
Topics: Allopurinol; Animals; Antioxidants; beta Carotene; Cell Hypoxia; Cells, Cultured; Cycloheximide; Dactinomycin; Deferoxamine; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; HSP70 Heat-Shock Proteins; Iron Chelating Agents; Male; Oxygen; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Reperfusion Injury | 2003 |
Oxidative mechanisms of IL-4-induced IL-6 expression in vascular endothelium.
Topics: Animals; Aorta; Arachidonic Acid; Cells, Cultured; Dactinomycin; Electron Transport; Endothelium, Vascular; Humans; Interleukin-4; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Oxidation-Reduction; Reactive Oxygen Species; Xanthine Oxidase | 2010 |
Increased oxidative stress induces apoptosis in human cystic fibrosis cells.
Topics: Acetophenones; Allopurinol; Apoptosis; Blotting, Western; Cell Line, Tumor; Cystic Fibrosis; Dactinomycin; Electron Spin Resonance Spectroscopy; Humans; NADPH Oxidases; Oxidative Stress; Superoxide Dismutase; Xanthine Oxidase | 2011 |