dactinomycin has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 19 (76.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garner, CW; Rice, KM | 1 |
| Roques, M; Vidal, H | 1 |
| Cotter, TG; Knox, KA; McGahon, AJ; McKenna, SL; O'Gorman, DM | 1 |
| Cuttle, KA; Goldstein, RH; Kuang, PP; Poliks, CF; Ricupero, DA; Rishikof, DC | 1 |
| Balmanno, K; Chalmers, C; Cook, SJ; Hadfield, K; Ley, R; Molton, SA; Wagner, EF; Weston, CR | 1 |
| Ihn, H; Tamaki, K; Yamane, K | 1 |
| Gajkowska, B; Godlewski, MM; Jank, M; Orzechowski, A; Ostaszewski, P; Sadkowski, T | 1 |
| Hansen, PB; Jensen, BL; Nørregaard, R; Schjerning, J; Skøtt, O; Sorensen, GL; Uhrenholt, TR | 1 |
| Anel, A; Boyer, C; Buferne, M; Martínez-Lorenzo, MJ; Naval, J; Pardo, J; Schmitt-Verhulst, AM | 1 |
| Bonanou, S; Chachami, G; Hatziefthimiou, A; Molyvdas, PA; Paraskeva, E; Simos, G | 1 |
| Chao, MV; Chen, ZY; Lee, FS; Rajagopal, R | 1 |
| Sullivan, CV; Weber, GM | 1 |
| Bentley, JK; Bitar, KN; Fingar, DC; Goldsmith, AM; Hershenson, MB; Jia, Y; Zhou, L | 1 |
| Anfossi, G; Doronzo, G; Mattiello, L; Russo, I; Trovati, M | 1 |
| Bhattacharyya, SP; Mukherjee, D; Paul, S; Sen, U | 1 |
| Kato, Y; Miura, Y; Oiso, Y; Ozaki, N; Yamada, T | 1 |
| Hanai, Y; Kozawa, O; Takai, S; Tokuda, H | 1 |
| Moore, AB; Sullivan, CV; Weber, GM | 1 |
| Ji, G; Lin, Z; Luo, S; Wu, Y; Yuan, C; Yuan, X | 1 |
| Augustin, HG; Ernst, E; Goettsch, C; Goettsch, W; Gryczka, C; Korff, T; Morawietz, H; Schnittler, HJ; Seebach, J | 1 |
| Kawai, G; Matsuhashi, A; Nagano, A; Ohno, T; Saitou, M; Shimizu, K; Takigami, I; Wakahara, K; Yamada, K; Yamamoto, T | 1 |
| Bredow, M; Brünnert, D; Ehrhardt, J; Goyal, P; Piccenini, S; Zygmunt, M | 1 |
| Borst, O; Fröhlich, H; Gawaz, M; Lang, F; Münzer, P; Pelzl, L; Schmid, E; Schmidt, EM; Tolios, A; Walker, B | 1 |
| Chang, HH; Huang, YM; Juan, CC; Kao, CC; Kao, YH; Kuo, YC; Liu, CW; Tang, YC | 1 |
| Maruyama, K; Morishita, E; Ohtake, S; Sekiya, A; Torishima, H | 1 |
25 other study(ies) available for dactinomycin and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
IGF-I regulates IRS-1 expression in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Chromones; Cycloheximide; Dactinomycin; Down-Regulation; Gene Expression Regulation; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Mice; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Binding; Receptor, Insulin; Up-Regulation | 1999 |
A phosphatidylinositol 3-Kinase/p70 ribosomal S6 protein kinase pathway is required for the regulation by insulin of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase gene expression in human muscle cells.
Topics: Adult; Cells, Cultured; Chromones; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glycogen Synthase; Humans; Insulin; Insulin Receptor Substrate Proteins; Middle Aged; Morpholines; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Ribosomal Protein S6 Kinases; RNA, Messenger; Signal Transduction; Sirolimus; Transcription, Genetic | 1999 |
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin | 2000 |
Phosphatidylinositol 3-kinase-dependent stabilization of alpha1(I) collagen mRNA in human lung fibroblasts.
Topics: 3T3 Cells; Androstadienes; Animals; Blotting, Northern; Cells, Cultured; Chromones; Collagen; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Kinetics; Lung; Mice; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA Stability; RNA, Messenger; Transfection; Wortmannin | 2001 |
Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Butadienes; Carrier Proteins; Cell Line; Chromones; Cricetinae; Cricetulus; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; JNK Mitogen-Activated Protein Kinases; Lung; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction | 2003 |
Epidermal growth factor up-regulates expression of transforming growth factor beta receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblast
Topics: Androstadienes; Cells, Cultured; Chromones; Dactinomycin; Dermis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Humans; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Scleroderma, Systemic; Signal Transduction; Transfection; Up-Regulation; Wortmannin | 2003 |
Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death.
Topics: Animals; Antioxidants; Apoptosis; Calcium Signaling; Calpain; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Chromones; Cyclic AMP; Dactinomycin; Dexamethasone; DNA; Glycoproteins; Hydrogen Peroxide; MAP Kinase Signaling System; Microscopy, Confocal; Microscopy, Electron; Microscopy, Phase-Contrast; Morpholines; Muscle Cells; Muscle Development; Muscle Fibers, Skeletal; Phosphatidylinositol 3-Kinases; Phospholipases A; Phospholipases A2; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Signal Transduction | 2003 |
Rapid inhibition of vasoconstriction in renal afferent arterioles by aldosterone.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Aorta; Arterioles; Benzoquinones; Calcium; Cells, Cultured; Chromones; Dactinomycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Heart Ventricles; Humans; In Vitro Techniques; Kidney; Lactams, Macrocyclic; Male; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinones; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Vasoconstriction | 2003 |
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
Topics: Acetophenones; Androstadienes; Animals; Antibodies, Monoclonal; Benzopyrans; Carbazoles; Cell Degranulation; Cell Line; Chromones; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Fas Ligand Protein; Humans; Indoles; Ionomycin; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Glycoproteins; Mice; Morpholines; Perforin; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pore Forming Cytotoxic Proteins; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Wortmannin | 2003 |
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.
Topics: Acetylcysteine; Androstadienes; Animals; Blotting, Western; Cell Nucleus; Chromones; Cobalt; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Models, Biological; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Plasmids; Potassium Chloride; Rabbits; Reactive Oxygen Species; Time Factors; Trachea; Transcription Factors; Transcription, Genetic; Transfection; Wortmannin | 2004 |
Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes.
Topics: Adenosine; Animals; Brefeldin A; Chromones; Cycloheximide; Dactinomycin; Enzyme Activation; Golgi Apparatus; Intracellular Membranes; Morpholines; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Nucleic Acid Synthesis Inhibitors; PC12 Cells; Phenethylamines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Prosencephalon; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, trkA; Receptor, trkB; Receptors, G-Protein-Coupled; Signal Transduction; Transcription, Genetic | 2004 |
Insulin-like growth factor-I induces oocyte maturational competence but not meiotic resumption in white bass (Morone chrysops) follicles in vitro: evidence for rapid evolution of insulin-like growth factor action.
Topics: 1-Octanol; Androstadienes; Animals; Bass; Chromones; Cortodoxone; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Female; Gap Junctions; Heptanol; Humans; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Meiosis; Morpholines; Oocytes; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Wortmannin | 2005 |
Transforming growth factor-beta induces airway smooth muscle hypertrophy.
Topics: Acetylcholine; Actin Cytoskeleton; Actins; Actomyosin; Adaptor Proteins, Signal Transducing; Bronchi; Carrier Proteins; Cell Cycle Proteins; Cell Size; Cells, Cultured; Chromones; Dactinomycin; Enzyme Inhibitors; Gene Expression; Humans; Hypertrophy; Morpholines; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Transforming Growth Factor beta | 2006 |
Homocysteine rapidly increases matrix metalloproteinase-2 expression and activity in cultured human vascular smooth muscle cells. Role of phosphatidyl inositol 3-kinase and mitogen activated protein kinase pathways.
Topics: Aorta; Cell Movement; Cells, Cultured; Chromones; Dactinomycin; Dose-Response Relationship, Drug; Flavonoids; Homocysteine; Humans; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphoinositide-3 Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Time Factors | 2005 |
In vitro effects of insulin-like growth factors and insulin on oocyte maturation and maturation-inducing steroid production in ovarian follicles of common carp, Cyprinus carpio.
Topics: Androstadienes; Animals; Carps; Cattle; Chorionic Gonadotropin; Chromones; Cycloheximide; Dactinomycin; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Insulin; Morpholines; Oocytes; Ovarian Follicle; Somatomedins; Species Specificity; Steroids; Time Factors; Wortmannin | 2006 |
Insulin downregulates angiopoietin-like protein 4 mRNA in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Angiopoietin-Like Protein 4; Angiopoietins; Animals; Blood Proteins; Chromones; Cycloheximide; Dactinomycin; Down-Regulation; Flavonoids; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Glucose; Insulin; Mice; Morpholines; Proto-Oncogene Proteins c-akt; RNA, Messenger; Tumor Necrosis Factor-alpha | 2006 |
Activation of phosphatidylinositol 3-kinase/Akt limits FGF-2-induced VEGF release in osteoblasts.
Topics: Androstadienes; Animals; Cells, Cultured; Chromones; Dactinomycin; Enzyme Activation; Fibroblast Growth Factor 2; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Morpholines; Osteoblasts; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A; Wortmannin | 2007 |
In vitro actions of insulin-like growth factor-I on ovarian follicle maturation in white perch (Morone americana).
Topics: Androstadienes; Animals; Bass; Chromones; Cycloheximide; Dactinomycin; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Morpholines; Ovarian Follicle; Phosphoinositide-3 Kinase Inhibitors; Recombinant Proteins; Sexual Maturation; Steroids; Wortmannin | 2007 |
Effects of different magnitudes of cyclic stretch on Na+-K+-ATPase in skeletal muscle cells in vitro.
Topics: Acid Sensing Ion Channels; Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Chromones; Dactinomycin; Ion Channel Gating; L-Lactate Dehydrogenase; Membrane Proteins; Morpholines; Muscle Fibers, Skeletal; Muscle Spindles; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Transport; Rats; RNA, Messenger; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Stress, Mechanical; Up-Regulation | 2007 |
Flow-dependent regulation of angiopoietin-2.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Benzoquinones; Cell Separation; Cells, Cultured; Chromones; Culture Media, Serum-Free; Dactinomycin; Endothelium, Vascular; Femoral Artery; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Lactams, Macrocyclic; Male; Mice; Mice, Inbred C57BL; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Phosphoinositide-3 Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Receptor, TIE-2; Regional Blood Flow; Rifabutin; RNA, Messenger; Signal Transduction; Stress, Mechanical; Triazenes; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Simultaneous inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways augment the sensitivity to actinomycin D in Ewing sarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Butadienes; Cell Death; Cell Line, Tumor; Chromones; Dactinomycin; Drug Resistance, Neoplasm; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oncogene Proteins, Fusion; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; RNA, Small Interfering; Sarcoma, Ewing; Signal Transduction; Transcription Factors; Transfection | 2009 |
Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways.
Topics: Amides; Aminoquinolines; Cell Line; Chromones; Cycloheximide; Dactinomycin; Female; Humans; Interleukin-6; Lysophospholipids; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Trophoblasts | 2013 |
Thrombin-sensitive expression of the store operated Ca(2+) channel Orai1 in platelets.
Topics: Androstadienes; Blood Platelets; Calcium; Calcium Channels; Chromones; Dactinomycin; Gene Expression Regulation; Humans; Morpholines; ORAI1 Protein; Phosphatidylinositol 3-Kinases; Platelet Activation; Puromycin; RNA Precursors; RNA, Messenger; Thrombin; Thrombosis; Time Factors; Wortmannin | 2013 |
Endothelin-1 stimulates resistin gene expression.
Topics: 3T3-L1 Cells; Adipose Tissue; Androstadienes; Animals; Anthracenes; Butadienes; Chromones; Dactinomycin; Endothelin-1; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Morpholines; Nitriles; Oligopeptides; Piperidines; Proto-Oncogene Proteins c-akt; Resistin; Signal Transduction; STAT3 Transcription Factor; Tyrphostins; Wortmannin | 2014 |
Fluvastatin Upregulates the Expression of Tissue Factor Pathway Inhibitor in Human Umbilical Vein Endothelial Cells.
Topics: Anticoagulants; Antigens; Blotting, Western; Cells, Cultured; Chromones; Dactinomycin; Fatty Acids, Monounsaturated; Fluvastatin; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Indoles; Lipoproteins; Luciferases; Maleimides; Mevalonic Acid; Morpholines; Pyridines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2015 |