dacarbazine has been researched along with mitozolomide in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, AS; Deans, B; Denny, BJ; Hartley, JA; Stevens, MF; Tisdale, MJ; Wheelhouse, RT | 1 |
| Clark, AS; Lowe, PR; Sansom, CE; Schwalbe, CH; Stevens, MF | 1 |
| Breistøl, K; Fodstad, O; Kjønniksen, I | 1 |
| Clark, AS; Sansom, CE; Schwalbe, CH; Stevens, MF | 1 |
| Bull, VL; Tisdale, MJ | 1 |
| Dive, C; Watson, JV; Workman, P | 1 |
| Tisdale, MJ | 2 |
| Erickson, LC; Gibson, NW; Hickman, JA | 2 |
| Lowe, PR; Schwalbe, CH | 1 |
| Newlands, ES; Stevens, MF | 1 |
| Bianchi, R; Binaglia, L; Bonmassar, E; D'Atri, S; Faraoni, I; Graziani, G; Grohmann, U; Margison, GP; Orlando, L; Watson, AJ | 1 |
| Chinnasamy, N; Dexter, TM; Fairbairn, LJ; Hickson, I; Lashford, LS; Margison, GP; Rafferty, JA; Thatcher, N | 1 |
| Arrowsmith, J; Missailidis, S; Stevens, MF | 1 |
| Lambert, P; Wang, D; Wang, Y; Zhao, L | 1 |
| Arrowsmith, J; Clark, AS; Jennings, SA; Stevens, MF | 1 |
| Bradshaw, TD; Laughton, CA; Madhusudan, S; Stevens, MF; Zhang, J | 1 |
18 other study(ies) available for dacarbazine and mitozolomide
| Article | Year |
|---|---|
Antitumor imidazotetrazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drug temozolomide.
Topics: Animals; Antineoplastic Agents; Base Sequence; Cell Survival; Dacarbazine; DNA; DNA Primers; Heterocyclic Compounds; Mice; Models, Molecular; Molecular Probes; Molecular Sequence Data; Temozolomide; Tumor Cells, Cultured | 1995 |
Antitumor imidazotetrazines. 25. Crystal structure of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) and structural comparisons with the related drugs mitozolomide and DTIC.
Topics: Antineoplastic Agents; Crystallography; Dacarbazine; Models, Molecular; Nitrogen Mustard Compounds; Structure-Activity Relationship; Temozolomide | 1992 |
Site-dependent differences in sensitivity of LOX human melanoma tumors in nude rats to dacarbazine and mitozolomide, but not to doxorubicin and cisplatin.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Neoplasms; Cisplatin; Dacarbazine; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Melanoma; Nitrogen Mustard Compounds; Rats; Rats, Nude; Skin Neoplasms; Transplantation, Heterologous | 1992 |
Anti-tumour imidazotetrazines. Part XXI. Mitozolomide and temozolomide: probes for the major groove of DNA.
Topics: Antineoplastic Agents; Dacarbazine; DNA; In Vitro Techniques; Models, Molecular; Nitrogen Mustard Compounds; Structure-Activity Relationship; Temozolomide | 1990 |
Antitumour imidazotetrazines--XVI. Macromolecular alkylation by 3-substituted imidazotetrazinones.
Topics: Alkylation; Antineoplastic Agents; Cell Line; Dacarbazine; DNA; Imidazoles; Nitrogen Mustard Compounds; Proteins; RNA; Temozolomide | 1987 |
Inhibition of cellular esterases by the antitumour imidazotetrazines mitozolomide and temozolomide: demonstration by flow cytometry and conventional spectrofluorimetry.
Topics: Animals; Antineoplastic Agents; Carmustine; Dacarbazine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esterases; Female; Flow Cytometry; Mammary Neoplasms, Experimental; Mesylates; Mice; Nitrogen Mustard Compounds; Spectrometry, Fluorescence; Temozolomide; Thiepins; Tumor Cells, Cultured | 1989 |
Antitumour imidazotetrazines and gene expression.
Topics: Alkylation; Antineoplastic Agents; Dacarbazine; DNA; Gene Expression Regulation; Imidazoles; Nitrogen Mustard Compounds; Temozolomide | 1988 |
Antitumor imidazotetrazines--XV. Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Chlorambucil; Colonic Neoplasms; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Guanine; Humans; Imidazoles; Kinetics; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Methyltransferases; Mice; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide | 1987 |
Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells.
Topics: Animals; Cell Division; Dacarbazine; DNA, Neoplasm; Ethylnitrosourea; Imidazoles; Kinetics; Leukemia L1210; Mice; Neoplasm Proteins; Nitrogen Mustard Compounds; Protein Binding | 1984 |
DNA cross-linking and cytotoxicity in normal and transformed human cells treated in vitro with 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d] -1,2,3,5-tetrazin-4(3H)-one.
Topics: Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Dacarbazine; DNA; Embryo, Mammalian; Humans; Imidazoles; Kinetics; Nitrogen Mustard Compounds | 1984 |
DCMCIT, an analogue of the antitumour drugs mitozolomide and temozolomide.
Topics: Antineoplastic Agents; Crystallography, X-Ray; Dacarbazine; Models, Molecular; Molecular Conformation; Molecular Structure; Nitrogen Mustard Compounds; Structure-Activity Relationship; Temozolomide | 1994 |
From triazines and triazenes to temozolomide.
Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chemistry, Pharmaceutical; Dacarbazine; Humans; Melanoma; Mice; Nitrogen Mustard Compounds; Prodrugs; Temozolomide | 1993 |
O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia.
Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Dacarbazine; DNA Damage; DNA Primers; Humans; Leukemia L1210; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Molecular Sequence Data; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Transfection; Triazines; Tumor Cells, Cultured | 1995 |
Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro.
Topics: Antigens, CD34; Antineoplastic Agents, Alkylating; Cell Line; Cell Survival; Dacarbazine; Gene Transfer Techniques; Genetic Vectors; Guanine; Hematopoietic Stem Cells; Humans; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Retroviridae; Temozolomide | 1998 |
Antitumour imidazotetrazines. Part 37. Conjugation of the DNA major-groove alkylating imidazotetrazine mitozolomide to peptide motifs recognizing the minor groove.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; Cattle; Circular Dichroism; Dacarbazine; DNA; DNA-Binding Proteins; Drug Carriers; Kinetics; Male; Molecular Sequence Data; Nitrogen Mustard Compounds; Nucleic Acid Conformation; Oligopeptides; Salmon; Spectrometry, Fluorescence; Substrate Specificity; Taq Polymerase; Temozolomide | 1999 |
Synthesis and antibacterial activity of dual-action agents of a beta-lactam antibiotic with cytotoxic agent mitozolomide or temozolomide.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; beta-Lactams; Dacarbazine; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Nitrogen Mustard Compounds; Structure-Activity Relationship; Temozolomide | 2002 |
Antitumor imidazotetrazines. 41. Conjugation of the antitumor agents mitozolomide and temozolomide to peptides and lexitropsins bearing DNA major and minor groove-binding structural motifs.
Topics: Amino Acids; Animals; Antineoplastic Agents; Cell Line; Dacarbazine; DNA; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Mice; Models, Molecular; Netropsin; Nitrogen Mustard Compounds; Peptides; Temozolomide; Tumor Cells, Cultured | 2002 |
Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications.
Topics: Antineoplastic Agents, Alkylating; Cell Cycle; Cell Line, Tumor; Dacarbazine; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Flow Cytometry; Glioblastoma; Glioma; Humans; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotide Array Sequence Analysis; Quinazolines; Temozolomide; Tumor Stem Cell Assay | 2010 |