dacarbazine has been researched along with methylnitrosourea in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Divo, AA; Patton, CL; Penketh, PG; Sartorelli, AC; Shyam, K | 1 |
| Baxter, D; Cunningham, TJ; Horton, J; Nelson, L; Olson, KB; Rosenbaum, C; Sponzo, RW; Taylor, SG | 1 |
| Bychkov, MB | 1 |
| Kogonia, LM; Moros, LW; Perevodchikova, NJ | 1 |
| Bychkov, MB; Perevodchikova, NI | 1 |
| Borisov, AI; Kogoniia, LM; Moroz, LV; Perevodchikova, NI; Platinskiĭ, LV | 1 |
| Kyrtopoulos, SA; Psaroudi, MC | 1 |
| Arends, MJ; Brookes, RA; Clarke, AR; Margison, GP; Sansom, OJ; Toft, NJ; Winton, DJ; Wood, M | 1 |
| Bishop, SM; Clarke, AR; Court, H; Dudley, S; Liskay, RM; Sansom, OJ | 1 |
| Akimov, MA; Gershanovich, ML | 1 |
| Caldwell, D; Kelley, MR; Rinne, M | 1 |
| Kitajima, Y; Koga, Y; Kohya, N; Miyazaki, K; Miyoshi, A; Sato, K | 1 |
| Guérard, M; Tang, L; Zeller, A | 1 |
| Chatziioannou, A; Kolisis, F; Koryllou, A; Moulos, P; Papadodima, O; Piroti, G; Pletsa, V | 1 |
| Ando, M; Inoue, Y; Iwase, Y; Kato, T; Muto, S; Uno, Y; Yamada, K | 1 |
3 trial(s) available for dacarbazine and methylnitrosourea
| Article | Year |
|---|---|
[Combination chemotherapy of disseminated skin melanoma with nitrosomethylurea].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dacarbazine; Dactinomycin; Drug Administration Schedule; Humans; Lomustine; Melanoma; Methylnitrosourea; Prognosis; Skin Neoplasms; Vincristine | 1986 |
[Comparison of the efficacy of imidazole-carboxamide and of a combination of nitrosomethylurea, vincristine and dactinomycin in disseminated melanoma].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Methylnitrosourea; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Skin Neoplasms; Time Factors; Vincristine | 1981 |
[Chemoimmunotherapy with dacarbazine and aranose combined with interferon-alpha in disseminated cutaneous melanoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Glycosides; Humans; Immunologic Factors; Interferon-alpha; Male; Melanoma; Methylnitrosourea; Middle Aged; Skin Neoplasms; Treatment Outcome | 2004 |
12 other study(ies) available for dacarbazine and methylnitrosourea
| Article | Year |
|---|---|
Methylating agents as trypanocides.
Topics: Alkylating Agents; Animals; Methylation; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis | 1990 |
Treatment of grade III and IV astrocytoma with dimethyl triazeno imidazole carboxamide (DTIC, NSC-45388) alone and in combination with CCNU (NSC-79037) or methyl CCNU (MeCCNU, NSC-95441).
Topics: Adult; Brain Neoplasms; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Glioblastoma; Humans; Leukopenia; Lomustine; Male; Methylnitrosourea; Middle Aged; Thrombocytopenia; Triazenes | 1975 |
[Chemotherapy and combined chemo- and radiotherapy of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Humans; Lomustine; Lung Neoplasms; Methotrexate; Methylnitrosourea; Procarbazine; Prospidium; Vincristine | 1985 |
Modern problems of clinical chemotherapy of malignant tumours.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Carubicin; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Methylnitrosourea; Neoplasms; Sarcoma; Skin Neoplasms; Soft Tissue Neoplasms; Vincristine | 1980 |
Toxicity, mutation frequency and mutation spectrum induced by dacarbazine in CHO cells expressing different levels of O(6)-methylguanine-DNA methyltransferase.
Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Dacarbazine; DNA Methylation; DNA Mutational Analysis; Enzyme Induction; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Liver Extracts; Male; Methylnitrosourea; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Rats; Rats, Sprague-Dawley | 2000 |
In vivo administration of O(6)-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biotransformation; Cisplatin; Cytochrome P-450 Enzyme System; Dacarbazine; DNA Damage; Enzyme Inhibitors; Guanine; Intestine, Small; Methylnitrosourea; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide | 2000 |
Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Animals; Apoptosis; Base Pair Mismatch; Bromodeoxyuridine; Carrier Proteins; Dacarbazine; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Intestine, Small; Male; Methylnitrosourea; Mice; Mice, Mutant Strains; Mismatch Repair Endonuclease PMS2; Mitotic Index; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Proto-Oncogene Proteins; Temozolomide; Time Factors | 2003 |
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Topics: Adenoviridae; Alkylating Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Therapy; Genetic Vectors; Humans; Hydroxylamines; Immunohistochemistry; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Oligonucleotides; Sensitivity and Specificity; Sulfuric Acid Esters; Temozolomide; Time Factors | 2004 |
Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Carrier Proteins; Cell Division; Cell Line, Tumor; Dacarbazine; Female; Flow Cytometry; G2 Phase; Gallbladder Neoplasms; Humans; Methylnitrosourea; Mice; Mice, Inbred BALB C; MutL Protein Homolog 1; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger | 2005 |
Quantitative assessment of the dose-response of alkylating agents in DNA repair proficient and deficient ames tester strains.
Topics: Alkylating Agents; Dacarbazine; DNA Helicases; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitrosourea; Methyltransferases; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Species Specificity; Temozolomide | 2014 |
Modulation of Pathways Underlying Distinct Cell Death Mechanisms in Two Human Lung Cancer Cell Lines in Response to SN1 Methylating Agents Treatment.
Topics: A549 Cells; Alkylating Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Dacarbazine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Humans; Lung Neoplasms; Methylnitrosourea; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Temozolomide | 2016 |
Evaluation of the mutagenicity of alkylating agents, methylnitrosourea and temozolomide, using the rat Pig-a assay with total red blood cells or reticulocytes.
Topics: Alkylating Agents; Animals; Body Weight; Dacarbazine; Erythrocytes; Male; Membrane Proteins; Methylnitrosourea; Mutagenicity Tests; Mutagens; Rats; Rats, Sprague-Dawley; Reticulocytes; Temozolomide | 2016 |