Compounds > dacarbazine

dacarbazine and folic acid

dacarbazine has been researched along with folic acid in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's10 (76.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bigner, DD; Friedman, HS; Johnson, SP; Kamen, BA1
Campion, L; Cartron, PF; Charbord, J; Debien, E; Hervouet, E; Menanteau, J; Vallette, FM1
Amighi, K; Gelbcke, M; Mathieu, V; Rosière, R; Van Antwerpen, P; Wauthoz, N1
Li, J; Liu, L; Liu, Q; Shen, C; Shezad, K; Tao, J; Xu, N; Zhang, L; Zhang, Y; Zhu, J1
Huang, J; Peng, Y; Shuai, X; Wu, T; Xiao, H1

Reviews

1 review(s) available for dacarbazine and folic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for dacarbazine and folic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Binding, Competitive; Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Inhibitory Concentration 50; O(6)-Methylguanine-DNA Methyltransferase; Receptors, Cell Surface; Temozolomide

2007
Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, May-15, Volume: 15, Issue:10

    Topics: Aged; Apoptosis; Apoptosis Regulatory Proteins; Becaplermin; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Modification Methylases; DNA Repair Enzymes; Folic Acid; Gene Expression Regulation, Neoplastic; Glioma; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Middle Aged; Neoplasm Invasiveness; Platelet-Derived Growth Factor; Protein Binding; Proto-Oncogene Proteins c-sis; Repetitive Sequences, Nucleic Acid; Sp1 Transcription Factor; Sp3 Transcription Factor; Survival Analysis; Survivin; Temozolomide; Tumor Suppressor Proteins

2009
New dry powders for inhalation containing temozolomide-based nanomicelles for improved lung cancer therapy.
    International journal of oncology, 2015, Volume: 47, Issue:3

    Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Cell Proliferation; Chemistry, Pharmaceutical; Dacarbazine; Dry Powder Inhalers; Folic Acid; Humans; Lung Neoplasms; Mice; Nanoparticles; Particle Size; Temozolomide

2015
Dacarbazine-Loaded Hollow Mesoporous Silica Nanoparticles Grafted with Folic Acid for Enhancing Antimetastatic Melanoma Response.
    ACS applied materials & interfaces, 2017, Jul-05, Volume: 9, Issue:26

    Topics: Dacarbazine; Folic Acid; Humans; Melanoma; Nanoparticles; Porosity; Silicon Dioxide

2017
Codelivery of temozolomide and siRNA with polymeric nanocarrier for effective glioma treatment.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug Delivery Systems; Folic Acid; Gene Silencing; Genes, bcl-2; Glioma; Humans; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Polyethyleneimine; Polymers; Proton Magnetic Resonance Spectroscopy; Rats; RNA, Messenger; RNA, Small Interfering; Static Electricity; Temozolomide

2018