dacarbazine has been researched along with aminoimidazole carboxamide in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crispen, R; Das Gupta, TK; El-Domeiri, AA; Sabet, TY; Simo, C; Trippon, M | 1 |
| Buesa, JM; Urréchaga, E | 1 |
| Fukushige, T; Ikeda, K; Nakagawara, A; Okuzono, S; Sue, K | 1 |
| Dandu, VR; Didolkar, MS; Fiore, D; Jackson, AJ | 1 |
| Aigner, K; Breithaupt, H; Dammann, A | 1 |
| Deres, J; Wasilewska, L | 1 |
| Kolar, GF; Maurer, M; Wildschütte, M | 1 |
| Alton, K; Baker, SD; Batra, V; Cutler, D; Donehower, RC; Dugan, M; Grochow, LB; Reidenberg, P; Rowinsky, EK; Sartorius, SE; Statkevich, P; Wirth, M | 1 |
| Heere-Ress, E; Jansen, B; Joukhadar, C; Klein, N; Mader, RM; Müller, M; Pehamberger, H; Rizovski, B; Schrolnberger, C; Strauchmann, N | 1 |
| Liu, Y; Yang, Y; Zhang, W | 1 |
| Andrasi, M; Bustos, R; Gaspar, A; Gomez, FA; Klekner, A | 1 |
| Armand, JP; Brendel, E; Lathia, C; Ludwig, M; Robert, C; Ropert, S; Soria, JC | 1 |
| Lopes, IC; Oliveira, SC; Oliveira-Brett, AM | 1 |
2 trial(s) available for dacarbazine and aminoimidazole carboxamide
| Article | Year |
|---|---|
Absorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancer.
Topics: Absorption; Administration, Oral; Adult; Aged; Aminoimidazole Carboxamide; Antineoplastic Agents, Alkylating; Blood Proteins; Carbon Radioisotopes; Dacarbazine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Temozolomide | 1999 |
Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors.
Topics: Aminoimidazole Carboxamide; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Dacarbazine; Disease Progression; Female; Humans; Male; Neoplasms; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Sorafenib | 2011 |
11 other study(ies) available for dacarbazine and aminoimidazole carboxamide
| Article | Year |
|---|---|
Adjuvant chemotherapy and immunotherapy in high risk patients with melanoma.
Topics: Adult; Aged; Aminoimidazole Carboxamide; BCG Vaccine; Dacarbazine; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Postoperative Care; Risk; Skin Neoplasms; Triazenes | 1978 |
Clinical pharmacokinetics of high-dose DTIC.
Topics: Aminoimidazole Carboxamide; Chromatography, High Pressure Liquid; Dacarbazine; Dose-Response Relationship, Drug; Drug Evaluation; Half-Life; Humans; Infusions, Intravenous; Time Factors | 1991 |
Different clonal drug sensitivity of murine neuroblastoma cells in vivo.
Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Body Weight; Cisplatin; Clone Cells; Cyclophosphamide; Dacarbazine; Female; Mice; Mice, Inbred A; Neuroblastoma; Tumor Cells, Cultured; Vincristine | 1988 |
Simultaneous determination of dacarbazine, its photolytic degradation product, 2-azahypoxanthine, and the metabolite 5-aminoimidazole-4-carboxamide in plasma and urine by high-pressure liquid chromatography.
Topics: Aminoimidazole Carboxamide; Chromatography, High Pressure Liquid; Dacarbazine; Humans; Hypoxanthines; Imidazoles; Kinetics; Melanoma | 1985 |
Pharmacokinetics of dacarbazine (DTIC) and its metabolite 5-aminoimidazole-4-carboxamide (AIC) following different dose schedules.
Topics: Adult; Aminoimidazole Carboxamide; Dacarbazine; Drug Administration Schedule; Female; Half-Life; Humans; Imidazoles; Infusions, Parenteral; Injections, Intravenous; Kinetics; Liver; Male; Middle Aged; Time Factors | 1982 |
[Polarographic determination of dacarbazine and aminoimidazole carboxamide in human blood and urine].
Topics: Aminoimidazole Carboxamide; Chemical Phenomena; Chemistry; Dacarbazine; Humans; Imidazoles; Polarography | 1981 |
5-(3-Hydroxymethyl-3-methyl-1-triazeno imidazole-4-carboxamide is a metabolite of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DIC, DTIC NSC-45388).
Topics: Aminoimidazole Carboxamide; Animals; Chromatography, Thin Layer; Dacarbazine; Male; Rats; Spectrum Analysis | 1980 |
Penetration of dacarbazine and its active metabolite 5-aminoimidazole-4-carboxamide into cutaneous metastases of human malignant melanoma.
Topics: Aged; Aminoimidazole Carboxamide; Antineoplastic Agents, Alkylating; Area Under Curve; Chromatography, High Pressure Liquid; Dacarbazine; Extracellular Space; Female; Humans; Male; Melanoma; Microdialysis; Middle Aged; Skin Neoplasms | 2001 |
Validated hydrophilic interaction LC-MS/MS method for simultaneous quantification of dacarbazine and 5-amino-4-imidazole-carboxamide in human plasma.
Topics: Aminoimidazole Carboxamide; Calibration; Chromatography, High Pressure Liquid; Dacarbazine; Humans; Hydrogen-Ion Concentration; Molecular Structure; Sensitivity and Specificity; Tandem Mass Spectrometry; Water | 2008 |
Analysis and stability study of temozolomide using capillary electrophoresis.
Topics: Aminoimidazole Carboxamide; Antineoplastic Agents, Alkylating; Chromatography, Micellar Electrokinetic Capillary; Dacarbazine; Drug Stability; Half-Life; Humans; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Temperature; Water | 2010 |
In situ electrochemical evaluation of anticancer drug temozolomide and its metabolites-DNA interaction.
Topics: Aminoimidazole Carboxamide; Antineoplastic Agents, Alkylating; Biosensing Techniques; Dacarbazine; Diazonium Compounds; DNA; Electrochemical Techniques; Humans; Neoplasms; Oxidation-Reduction; Temozolomide | 2013 |