Compounds > dacarbazine

dacarbazine and 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide

dacarbazine has been researched along with 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Gescher, A; Quarterman, CP; Slack, JA; Tsang, LL1
Babudri, N; Bartoli-Klugmann, F; Montibragadin, C; Pani, B; Tamaro, M; Venturini, S1
Kolar, GF; Maurer, M; Wildschütte, M1
Ames, MM; Reid, JM; Rios, R; Safgren, SL1
Andrasi, M; Bustos, R; Gaspar, A; Gomez, FA; Klekner, A1
Ames, MM; Easterling, TR; Hays, K; Hebert, MF; Kantrowitz-Gordon, I; Kaplan, HG; Kayode, O; Kumar, AR; Reid, JM; Safgren, SL1
Finnegan, A; Levay, P1

Other Studies

7 other study(ies) available for dacarbazine and 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide

ArticleYear
Comparison of the cytotoxicity in vitro of temozolomide and dacarbazine, prodrugs of 3-methyl-(triazen-1-yl)imidazole-4-carboxamide.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Division; Chromatography, High Pressure Liquid; Dacarbazine; Lymphoma; Mice; Prodrugs; Temozolomide; Tumor Cells, Cultured

1991
In vitro mutagenic activity of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) in eukaryotic and prokaryotic cells.
    Carcinogenesis, 1982, Volume: 3, Issue:5

    Topics: Animals; Cell Count; Cell Line; Cricetinae; Cricetulus; Dacarbazine; Dose-Response Relationship, Drug; Escherichia coli; Mutagenicity Tests; Mutation; Salmonella typhimurium

1982
5-(3-Hydroxymethyl-3-methyl-1-triazeno imidazole-4-carboxamide is a metabolite of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (DIC, DTIC NSC-45388).
    Cancer letters, 1980, Volume: 10, Issue:3

    Topics: Aminoimidazole Carboxamide; Animals; Chromatography, Thin Layer; Dacarbazine; Male; Rats; Spectrum Analysis

1980
Validated high-performance liquid chromatographic assay for simultaneous determination of dacarbazine and the plasma metabolites 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-methyl-1-triazeno)imidazole-4-carboxamide.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Apr-15, Volume: 754, Issue:1

    Topics: Chromatography, High Pressure Liquid; Clinical Trials, Phase II as Topic; Dacarbazine; Drug Stability; Humans; Models, Chemical; Reproducibility of Results

2001
Analysis and stability study of temozolomide using capillary electrophoresis.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Jul-01, Volume: 878, Issue:21

    Topics: Aminoimidazole Carboxamide; Antineoplastic Agents, Alkylating; Chromatography, Micellar Electrokinetic Capillary; Dacarbazine; Drug Stability; Half-Life; Humans; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Temozolomide; Temperature; Water

2010
Pharmacokinetics of dacarbazine (DTIC) in pregnancy.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:3

    Topics: Administration, Intravenous; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bleomycin; Dacarbazine; Doxorubicin; Drug Monitoring; Female; Hodgkin Disease; Humans; Infant, Newborn; Neoplasm Staging; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Treatment Outcome; Vinblastine

2018
A method for translating search strategies efficiently into HMIC and SPP.
    Health information and libraries journal, 2022, Volume: 39, Issue:3

    Topics: Dacarbazine; Databases, Bibliographic; Humans; Information Storage and Retrieval; MEDLINE; Public Policy; Subject Headings

2022