Compounds > dacarbazine

dacarbazine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

dacarbazine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleau, AM; Brennan, CW; Fomchenko, EI; Hambardzumyan, D; Holland, EC; Huse, JT; Ozawa, T1
Chen, L; Han, L; Jiang, C; Jiang, T; Kang, C; Liu, Y; Pu, P; Shi, Z; Zhang, K; Zheng, Y1
Fei, X; Shi, L; Wang, Z; You, Y1
Chosdol, K; Das, BC; Jalota, A; Kumar, M; Sinha, S; Yadav, AK1
Egorova, AV; Emelyanova, MA; Inshakov, AN; Khochenkov, DA; Nasedkina, TV; Ryabaya, OO; Stepanova, EV; Zasedatelev, AS1

Other Studies

5 other study(ies) available for dacarbazine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.
    Cell stem cell, 2009, Mar-06, Volume: 4, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Cells, Cultured; Chromones; Dacarbazine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glioma; Humans; Mice; Mice, Nude; Mitoxantrone; Morpholines; Neoplasm Proteins; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Temozolomide

2009
LY294002 enhances cytotoxicity of temozolomide in glioma by down-regulation of the PI3K/Akt pathway.
    Molecular medicine reports, 2012, Volume: 5, Issue:2

    Topics: Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Chromones; Dacarbazine; Down-Regulation; Drug Synergism; Glioma; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Temozolomide

2012
PI3K inhibitor combined with miR-125b inhibitor sensitize TMZ-induced anti-glioma stem cancer effects through inactivation of Wnt/β-catenin signaling pathway.
    In vitro cellular & developmental biology. Animal, 2015, Volume: 51, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Cell Movement; Cell Survival; Chromones; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Humans; MicroRNAs; Morpholines; Neoplasm Invasiveness; Neoplastic Stem Cells; Phosphoinositide-3 Kinase Inhibitors; Primary Cell Culture; Temozolomide; Tumor Cells, Cultured; Wnt Proteins; Wnt Signaling Pathway

2015
Synergistic increase in efficacy of a combination of 2-deoxy-D-glucose and cisplatin in normoxia and hypoxia: switch from autophagy to apoptosis.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; bcl-2-Associated X Protein; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Chromones; Cisplatin; Dacarbazine; Deoxyglucose; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression; Glioblastoma; Humans; Morpholines; Oxygen; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide

2016
Autophagy inhibitors chloroquine and LY294002 enhance temozolomide cytotoxicity on cutaneous melanoma cell lines in vitro.
    Anti-cancer drugs, 2017, Volume: 28, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Chloroquine; Chromones; Dacarbazine; Drug Synergism; Humans; Melanoma; Morpholines; Skin Neoplasms; Temozolomide

2017