dabigatran has been researched along with omeprazole in 7 studies
| Studies (dabigatran) | Trials (dabigatran) | Recent Studies (post-2010) (dabigatran) | Studies (omeprazole) | Trials (omeprazole) | Recent Studies (post-2010) (omeprazole) |
|---|---|---|---|---|---|
| 3,887 | 261 | 3,490 | 9,085 | 2,737 | 1,487 |
| Protein | Taxonomy | dabigatran (IC50) | omeprazole (IC50) |
|---|---|---|---|
| Mcl-1 | Homo sapiens (human) | 3.1448 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.28 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 1.45 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 2.315 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 1.45 | |
| WD repeat-containing protein 5 | Homo sapiens (human) | 1.7 | |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | 4.6 | |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | 1.7 | |
| Muscarinic acetylcholine receptor | Cavia porcellus (domestic guinea pig) | 3.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ahnfelt, L; Dahl, OE; Eriksson, BI; Nehmiz, G; Rathgen, K; Stähle, H; Stangier, J; Svärd, R | 1 |
| Accassat, S; Basset, T; Bertoletti, L; Delavenne, X; Hodin, S; Mismetti, P; Ollier, E | 1 |
| Bangdiwala, SI; Berwanger, O; Biccard, BM; Botto, F; Chaudhry, NK; Connolly, SJ; de Nadal, M; Devereaux, PJ; Duceppe, E; Eikelboom, JW; Franzosi, MG; Guyatt, G; Kearon, C; Magloire, P; Mayosi, B; Meyhoff, CS; Neary, J; Parlow, J; Pettit, S; Popova, E; Rao, M; Rodseth, R; Sessler, DI; Sharma, M; Srinathan, SK; Szczeklik, W; Tandon, V; Villar, JC; Vincent, J; Xavier, D; Yusuf, S | 1 |
| Bangdiwala, SI; Berwanger, O; Biccard, BM; Botto, F; Chaudhry, NK; Connolly, SJ; de Nadal, M; Devereaux, PJ; Duceppe, E; Eikelboom, JW; Erb, J; Franzosi, MG; Guyatt, G; Hoeft, A; Iglesias, PP; Kearon, C; Magloire, P; Mayosi, B; Meyhoff, CS; Neary, J; Pettit, S; Rahate, PV; Rao, M; Rao-Melacini, P; Rodseth, R; Sessler, DI; Sharma, M; Srinathan, SK; Szczeklik, W; Tandon, V; Villar, JC; Vincent, J; Xavier, D; Yusuf, S | 1 |
| Bánovčin, P; Bolek, T; Galajda, P; Kubisz, P; Lipták, P; Mokán, M; Samoš, M; Schnierer, M; Škorňová, I; Staško, J; Urban, L | 1 |
| Bánovčin, P; Bolek, T; Galajda, P; Hyrdel, R; Kubisz, P; Mokáň, M; Nosáková, L; Samoš, M; Schnierer, M; Škorňová, I; Stasko, J | 1 |
| Leung, A; Mahawish, KM | 1 |
4 trial(s) available for dabigatran and omeprazole
| Article | Year |
|---|---|
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Administration, Oral; Adult; Aged; Aged, 80 and over; Area Under Curve; Arthroplasty, Replacement, Hip; Benzimidazoles; Cross-Over Studies; Dabigatran; Drug Interactions; Female; Food-Drug Interactions; Humans; Male; Metabolic Clearance Rate; Middle Aged; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Pyridines; Sulfoxides; Thrombin | 2005 |
In vitro and in vivo evaluation of drug-drug interaction between dabigatran and proton pump inhibitors.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line, Tumor; Cyclosporine; Dabigatran; Drug Interactions; Humans; Lansoprazole; Male; Omeprazole; Pantoprazole; Proton Pump Inhibitors; Rabeprazole; Thrombin; Young Adult | 2015 |
Design of a Randomized Placebo-Controlled Trial to Assess Dabigatran and Omeprazole in Patients with Myocardial Injury after Noncardiac Surgery (MANAGE).
Topics: Aged; Cause of Death; Dabigatran; Double-Blind Method; Female; Follow-Up Studies; Humans; Internationality; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Omeprazole; Postoperative Complications; Proportional Hazards Models; Risk Assessment; Surgical Procedures, Operative; Survival Analysis; Treatment Outcome | 2018 |
Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Antithrombins; Dabigatran; Female; Hemorrhage; Humans; Male; Myocardial Infarction; Omeprazole; Perioperative Period; Peripheral Arterial Disease; Placebo Effect; Proton Pump Inhibitors; Stroke; Thrombosis; Treatment Outcome; Troponin; Venous Thromboembolism | 2018 |
3 other study(ies) available for dabigatran and omeprazole
| Article | Year |
|---|---|
Dabigatran levels in omeprazole versus pantoprazole-treated patients with atrial fibrillation: is there a difference?
Topics: Aged; Aged, 80 and over; Antithrombins; Atrial Fibrillation; Dabigatran; Drug Interactions; Female; Humans; Male; Middle Aged; Omeprazole; Pantoprazole; Pilot Projects; Prospective Studies; Proton Pump Inhibitors | 2019 |
The Effect of Proton Pump Inhibitor Withdrawal on Dabigatran Etexilate Plasma Levels in Patients With Atrial Fibrillation: A Washout Study.
Topics: Aged; Aged, 80 and over; Antithrombins; Atrial Fibrillation; Dabigatran; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Omeprazole; Pantoprazole; Pilot Projects; Prospective Studies; Proton Pump Inhibitors; Time Factors; Treatment Outcome | 2020 |
Failure of dabigatran following idarucizumab and omeprazole administration.
Topics: Antibodies, Monoclonal, Humanized; Antithrombins; Dabigatran; Humans; Omeprazole | 2021 |