dabigatran has been researched along with digoxin in 9 studies
| Studies (dabigatran) | Trials (dabigatran) | Recent Studies (post-2010) (dabigatran) | Studies (digoxin) | Trials (digoxin) | Recent Studies (post-2010) (digoxin) |
|---|---|---|---|---|---|
| 3,887 | 261 | 3,490 | 11,483 | 958 | 1,289 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Körnicke, T; Rathgen, K; Reseski, K; Roth, W; Stähle, H; Stangier, J | 1 |
| Ebner, T; Ishiguro, N; Kishimoto, W; Ludwig-Schwellinger, E; Schaefer, O | 1 |
| Hu, ZY; Zhao, Y | 1 |
| Chu, X; Galetin, A; Tweedie, DJ; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Akamine, Y; Uno, T; Yasui-Furukori, N | 1 |
| Bergfeldt, L; Blomström-Lundqvist, C; Boriani, G; Botto, GL; Camm, AJ; Capucci, A; Goette, A; Hohnloser, SH; Israel, CW; Lozano, IF; Merino, JL | 1 |
| Costales, C; Eatemadpour, S; Kimoto, E; Lazzaro, S; Varma, MV; Yamazaki, S | 1 |
| De Zwart, L; Evers, R; Yamazaki, S | 1 |
| Cui, C; Jiang, Y; Li, H; Ling, J; Liu, D; Pan, J; Qu, Y; Sia, JEV; Wang, Y; Zhu, Z | 1 |
2 review(s) available for dabigatran and digoxin
| Article | Year |
|---|---|
Drug-Drug Interactions of P-gp Substrates Unrelated to CYP Metabolism.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Dabigatran; Digoxin; Drug Interactions; Humans; Propanolamines; Terfenadine | 2019 |
Safety and efficacy of dronedarone from clinical trials to real-world evidence: implications for its use in atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Antithrombins; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Factor Xa Inhibitors; Heart Failure; Hospitalization; Humans; Mortality; Pyridines; Randomized Controlled Trials as Topic; Thiazoles | 2019 |
1 trial(s) available for dabigatran and digoxin
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor, with coadministration of digoxin.
Topics: Adult; Anti-Arrhythmia Agents; Antithrombins; Area Under Curve; Benzimidazoles; Biological Availability; Blood Coagulation; Cross-Over Studies; Dabigatran; Digoxin; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Middle Aged; Pyridines | 2012 |
6 other study(ies) available for dabigatran and digoxin
| Article | Year |
|---|---|
In vitro predictability of drug-drug interaction likelihood of P-glycoprotein-mediated efflux of dabigatran etexilate based on [I]2/IC50 threshold.
Topics: Antithrombins; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Biological Transport; Caco-2 Cells; Dabigatran; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Intestinal Mucosa; Intestines; Liver; Models, Biological; Pyridines; Risk Assessment | 2014 |
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil | 2014 |
Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Caco-2 Cells; Dabigatran; Digoxin; Drug Interactions; Drug Stability; Humans; Intestinal Absorption; Risk Assessment | 2018 |
Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction.
Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dabigatran; Digoxin; Drug Interactions; Female; Gene Expression Regulation; Healthy Volunteers; Humans; Intestinal Mucosa; Male; Models, Biological; Propanolamines; Quinidine; Rifampin | 2019 |
Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Dabigatran; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestines; Itraconazole; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Quinidine; Verapamil; Young Adult | 2022 |
Assessment of Aging-Related Function Variations of P-gp Transporter in Old-Elderly Chinese CHF Patients Based on Modeling and Simulation.
Topics: Adult; Age Factors; Aged; Aging; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Dabigatran; Digoxin; East Asian People; Heart Failure; Humans; Middle Aged | 2022 |