dabigatran has been researched along with clarithromycin in 6 studies
| Studies (dabigatran) | Trials (dabigatran) | Recent Studies (post-2010) (dabigatran) | Studies (clarithromycin) | Trials (clarithromycin) | Recent Studies (post-2010) (clarithromycin) |
|---|---|---|---|---|---|
| 3,887 | 261 | 3,490 | 7,149 | 1,606 | 2,504 |
| Protein | Taxonomy | dabigatran (IC50) | clarithromycin (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 5.5 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 3.3113 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.0903 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Accassat, S; Basset, T; Bertoletti, L; Delavenne, X; Garcin, A; Laporte, S; Mismetti, P; Ollier, E; Zufferey, P | 1 |
| Hu, ZY; Zhao, Y | 1 |
| Azizi, M; Beaune, P; Blanchard, A; Delavenne, X; Funck-Brentano, C; Gaussem, P; Gouin-Thibault, I; Loriot, MA; Mismetti, P; Narjoz, C; Salem, JE; Siguret, V | 1 |
| Carrier, M; Clark, EG; Garg, AX; Harel, Z; Hill, K; Hundemer, GL; Knoll, G; McArthur, E; Rhodes, E; Sood, MM; Sucha, E | 1 |
| Bykov, K; Gagne, JJ; Kim, S; Li, H; Lo Re, V; Vine, SM | 1 |
| Cui, C; Lai, X; Li, H; Liu, D; Sia, JEV; Wu, X; Zhang, F | 1 |
2 trial(s) available for dabigatran and clarithromycin
| Article | Year |
|---|---|
A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin.
Topics: Adolescent; Adult; Antithrombins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Biological Availability; Blood Coagulation Tests; Clarithromycin; Cross-Over Studies; Dabigatran; Drug Interactions; Endopeptidases; Humans; Male; Models, Biological; Nonlinear Dynamics; Pyridines; Young Adult | 2013 |
Interindividual variability in dabigatran and rivaroxaban exposure: contribution of ABCB1 genetic polymorphisms and interaction with clarithromycin.
Topics: Adolescent; Adult; Alleles; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dabigatran; Genotype; Heterozygote; Homozygote; Humans; Male; Middle Aged; Mutation; Polymorphism, Genetic; Rivaroxaban; Young Adult | 2017 |
4 other study(ies) available for dabigatran and clarithromycin
| Article | Year |
|---|---|
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil | 2014 |
Risk of Hospitalization With Hemorrhage Among Older Adults Taking Clarithromycin vs Azithromycin and Direct Oral Anticoagulants.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Dabigatran; Drug Interactions; Factor Xa Inhibitors; Female; Hemorrhage; Hospitalization; Humans; Male; Pyrazoles; Pyridones; Retrospective Studies; Risk Factors; Rivaroxaban | 2020 |
Drug-Drug Interaction Surveillance Study: Comparing Self-Controlled Designs in Five Empirical Examples in Real-World Data.
Topics: Aged; Atorvastatin; Clarithromycin; Dabigatran; Databases, Factual; Drug Evaluation; Drug Interactions; Evidence-Based Medicine; Female; Humans; Male; Middle Aged; Simvastatin; United States; Valsartan | 2021 |
Physiologically-based pharmacokinetic modeling to predict drug-drug interactions of dabigatran etexilate and rivaroxaban in the Chinese older adults.
Topics: Administration, Oral; Aged; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Member 1; China; Clarithromycin; Dabigatran; Drug Interactions; East Asian People; Humans; Rivaroxaban; Verapamil | 2023 |