Page last updated: 2024-09-05

dabigatran and amiodarone

dabigatran has been researched along with amiodarone in 16 studies

Compound Research Comparison

Studies
(dabigatran)
Trials
(dabigatran)
Recent Studies (post-2010)
(dabigatran)
Studies
(amiodarone)
Trials
(amiodarone)
Recent Studies (post-2010) (amiodarone)
3,8872613,4908,1567431,889

Protein Interaction Comparison

ProteinTaxonomydabigatran (IC50)amiodarone (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.27
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.085
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.404
Bile salt export pumpHomo sapiens (human)10
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)9.148
Tyrosine-protein kinase FynHomo sapiens (human)0.817
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.271
Muscarinic acetylcholine receptor M2Homo sapiens (human)5.08
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.63
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.499
Alpha-2A adrenergic receptorHomo sapiens (human)0.312
Thyroid hormone receptor alphaHomo sapiens (human)0.65
Thyroid hormone receptor betaHomo sapiens (human)0.6
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.613
Lethal factorBacillus anthracis3.5
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.201
D(1A) dopamine receptorHomo sapiens (human)9.142
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.271
5-hydroxytryptamine receptor 2AHomo sapiens (human)3.59
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.404
Sodium-dependent serotonin transporterHomo sapiens (human)2.305
Melanocortin receptor 5Homo sapiens (human)9.497
D(3) dopamine receptorHomo sapiens (human)1.208
Sodium channel protein type 1 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 4 subunit alphaHomo sapiens (human)4.8
Squalene synthaseHomo sapiens (human)8
Delta-type opioid receptorHomo sapiens (human)8.014
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.923
Sodium channel protein type 7 subunit alphaHomo sapiens (human)4.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.085
Sodium-dependent dopamine transporter Homo sapiens (human)2.505
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)6.206
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.085
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.085
Sodium channel protein type 5 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 9 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 2 subunit alphaHomo sapiens (human)4.8
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.097
Sodium channel protein type 3 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 11 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 8 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 10 subunit alphaHomo sapiens (human)4.8

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's15 (93.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Laufs, U; Röther, J1
Crijns, H; Röther, J1
Gil Núñez, A1
Abdollah, H; Baranchuk, AM; Michael, KA; Miranda, RI; Redfearn, DP; Simpson, CS1
Dobrev, D1
Khanna, V; Reynolds, M; Reynolds, MR; Rutzen-Lopez, H; Vkhanna, V1
Aikens, TH; Ezekowitz, MD; Nagarakanti, R; Shapiro, T1
Calkins, H; Lim, SH; Sinha, SK1
Ahmad, Y; Lip, GY1
Fountzilas, C; George, J; Levine, R1
Hu, ZY; Zhao, Y1
Juhlin, T; Mochalina, N; Platonov, PG; Svensson, PJ; Wieloch, M1
Bottoni, A; Catapano, GA; Genovesi, D; Iervasi, G; Panchetti, L; Sbrana, F1
Brookes, C; Lock, J; Patel, JP; Patel, RK1
Chung, CP; Daugherty, JR; Dickson, AL; Dupont, WD; Hung, AM; Murray, KT; Ray, WA; Smalley, W; Stein, CM; Zimmerman, E1

Reviews

6 review(s) available for dabigatran and amiodarone

ArticleYear
[Preventing stroke by treating atrial fibrillation--new hope with dronedarone and dabigatran?].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135 Suppl 2

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; Dabigatran; Dronedarone; Drug Therapy, Combination; Humans; Pyridines; Risk Factors; Stroke; Survival Rate; Thrombin; Vitamin K

2010
Prevention of stroke in patients with atrial fibrillation: the role of new antiarrhythmic and antithrombotic drugs.
    Cerebrovascular diseases (Basel, Switzerland), 2010, Volume: 30, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzimidazoles; Dabigatran; Dronedarone; Fibrinolytic Agents; Humans; Pyridines; Risk Factors; Stroke

2010
Advances in the treatment of atrial fibrillation.
    Minerva cardioangiologica, 2010, Volume: 58, Issue:6

    Topics: Amiodarone; Anisoles; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Catheter Ablation; Dabigatran; Dronedarone; Drug Therapy, Combination; Heart Conduction System; Humans; Pyrrolidines; Treatment Outcome

2010
Atrial fibrillation: epidemiology, prognosis and therapy.
    Minerva medica, 2011, Volume: 102, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Appendage; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Catheter Ablation; Dabigatran; Dronedarone; Electric Countershock; Heart Rate; Humans; Prognosis; Quality of Life; Risk Factors; Thromboembolism

2011
Update on the management of atrial fibrillation: anticoagulation and medical therapy.
    Current cardiology reports, 2011, Volume: 13, Issue:5

    Topics: Amiodarone; Anisoles; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; Dabigatran; Dronedarone; Drug Approval; Evidence-Based Medicine; Factor Xa Inhibitors; Female; Humans; Infusions, Intravenous; Male; Practice Guidelines as Topic; Pyridines; Pyrrolidines; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration

2011
Stroke prevention in atrial fibrillation: concepts and controversies.
    Current cardiology reviews, 2012, Volume: 8, Issue:4

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clinical Trials, Phase III as Topic; Dabigatran; Dronedarone; Drug Design; Humans; Morpholines; Pyrazoles; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Thiophenes; Treatment Outcome; Warfarin

2012

Other Studies

10 other study(ies) available for dabigatran and amiodarone

ArticleYear
[Advances in the prevention of cerebral ischaemia due to atrial fibrillation].
    Neurologia (Barcelona, Spain), 2010, Volume: 25, Issue:7

    Topics: Amiodarone; Anticoagulants; Antifibrinolytic Agents; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Brain Ischemia; Dabigatran; Diagnosis, Differential; Dronedarone; Humans; Vitamin K

2010
Prevention of atrial fibrillation complications with antiarrhythmic drugs: still an unmet need in clinical practice.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Dronedarone; Heart Rate; Humans; Stroke

2011
Atrial fibrillation: outpatient presentation and management.
    Circulation, 2011, Jul-05, Volume: 124, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Dronedarone; Electrocardiography; Heart Rate; Humans; Male; Outpatients; Stroke; Treatment Outcome

2011
[Update on current care guidelines: atrial fibrillation].
    Duodecim; laaketieteellinen aikakauskirja, 2012, Volume: 128, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Dronedarone; Finland; Humans; Morpholines; Practice Guidelines as Topic; Rivaroxaban; Thiophenes; Warfarin

2012
Dabigatran overdose secondary to acute kidney injury and amiodarone use.
    The New Zealand medical journal, 2013, Mar-01, Volume: 126, Issue:1370

    Topics: Acute Kidney Injury; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Creatinine; Dabigatran; Drug Overdose; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Thrombin Time

2013
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
    British journal of pharmacology, 2014, Volume: 171, Issue:4

    Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil

2014
Concomitant use of dronedarone with dabigatran in patients with atrial fibrillation in clinical practice.
    Thrombosis research, 2015, Volume: 135, Issue:6

    Topics: Aged; Amiodarone; Anticoagulants; Antithrombins; Atrial Fibrillation; Cohort Studies; Dabigatran; Dronedarone; Female; Glomerular Filtration Rate; Healthy Volunteers; Hemorrhage; Humans; Male; Middle Aged; Prospective Studies; Registries; Time Factors; Treatment Outcome

2015
Dabigatran malabsorption in amiodarone-induced thyrotoxicosis: a clinical report.
    Internal and emergency medicine, 2016, Volume: 11, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dabigatran; Echocardiography; Humans; International Normalized Ratio; Malabsorption Syndromes; Male; Prothrombin Time; Thyrotoxicosis

2016
Clinical Experience of Prescribing Dabigatran Etexilate With Dronedarone: The Role of Therapeutic Drug Monitoring.
    Therapeutic drug monitoring, 2016, Volume: 38, Issue:6

    Topics: Adult; Aged; Amiodarone; Antithrombins; Dabigatran; Dronedarone; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male

2016
Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study.
    Annals of internal medicine, 2023, Volume: 176, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Dabigatran; Embolism; Female; Flecainide; Hemorrhage; Hospitalization; Humans; Ischemic Stroke; Male; Medicare; Retrospective Studies; Rivaroxaban; Sotalol; Stroke; United States

2023