Page last updated: 2024-08-25

d-aspartic acid and n-methylaspartate

d-aspartic acid has been researched along with n-methylaspartate in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (34.48)29.6817
2010's15 (51.72)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Bottino, MC; Duvilanski, BH; Lasaga, M; Pampillo, M; Rettori, V; Scimonelli, T; Seilicovich, A1
Awe, SO; Harris, LC; Kulkarni, K; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA1
Bai, D; Frandsen, A; Gong, XQ; Lu, WY; Pickering, DS; Wan, Y; Zabek, RL1
Boni, R; D'Aniello, A; Ferrandino, G; Macchia, G; Santillo, R; Spinelli, P1
Affuso, A; D'Aniello, A; De Felice, M; Di Lauro, R; Errico, F; Pirro, MT; Spinelli, P1
D'Aniello, A1
Boeck, CR; Bronzatto, MJ; Kroth, EH; Vendite, D1
Fisher, G; Galindo, E; Szókán, G; Tsesarskaia, M1
Dan, B1
Eby, GA; Eby, KL1
Chen, Y; Guillemin, GJ; Meininger, V1
Huang, LT; Lodge, D; Sherwood, JL; Sun, YJ; Wang, Y1
Choi, IG; Choi, KC; Hong, EJ; Jeung, EB; Jung, EM; Kang, HY; Kim, JY; Lee, GS; Na, KJ; Park, MJ; Seong, YH1
Bertolotti, D; Green, TL; Grover, LM; Kim, E1
Bi, Y; Fan, G; Feng, C; Lin, F; Wang, C; Wu, F; Xiao, Y; Yan, J; Ye, W; Zhu, G1
Cao, WH; Madden, CJ; Morrison, SF1
David, KK; Dawson, TM; Dawson, VL; Koehler, RC; Li, X; Xu, Z; Yang, ZJ; Zhang, J1
Knutson, N; Wood, CE1
Boije, H; Hallböök, F; López-Gallardo, M; Prada, C; Ring, H1
Di Prisco, S; Grilli, M; Marchi, M; Pittaluga, A; Summa, M1
Bagetta, V; Bonito-Oliva, A; Calabresi, P; Carta, M; Di Luca, M; Errico, F; Fisone, G; Gardoni, F; Marinucci, S; Napolitano, F; Picconi, B; Romano, R; Usiello, A; Vitucci, D; Zianni, E1
Fisher, GH; Tsesarskaia, M1
Bertoldo, DB; Constantino, LC; Dal-Cim, T; Martins, WC; Molz, S; Severino, PC; Silva, FR; Tasca, CI; Vandresen-Filho, S1
Homma, H; Kaneko, Y; Katane, M; Kawata, T; Matsuda, S; Miyamoto, T; Nakayama, K; Saitoh, Y; Sekine, M1
Choragiewicz, TJ; Gasior, M; Rejdak, R; Schuettauf, F; Thaler, S; Zarnowska, I; Zarnowski, T; Zrenner, E1
Chieffi Baccari, G; De Rosa, A; Di Fiore, MM; Errico, F; Falvo, S; Nuzzo, T; Santillo, A; Usiello, A1
Chieffi Baccari, G; Cioffi, F; Di Fiore, MM; Falvo, S; Santillo, A1
Akdağlı Ekici, A; Alagöz, A; Ayaz, E; Doğan, G; Karaca, O; Kayır, S; Özcan, O; Yağan, Ö; Yalvaç, M; Zengin, EN; Zengin, M1
Bonanno, G; Bonifacino, T; Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Micheli, L; Milanese, M; Scherz, MW; Torazza, C1

Reviews

4 review(s) available for d-aspartic acid and n-methylaspartate

ArticleYear
D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role.
    Brain research reviews, 2007, Volume: 53, Issue:2

    Topics: Animals; D-Aspartic Acid; Humans; N-Methylaspartate; Nervous System; Neurosecretory Systems

2007
Angelman syndrome: current understanding and research prospects.
    Epilepsia, 2009, Volume: 50, Issue:11

    Topics: Angelman Syndrome; Animals; Brain; Cerebellum; Chromosomes, Human, Pair 15; D-Aspartic Acid; Dendritic Spines; Disease Models, Animal; Electrical Synapses; gamma-Aminobutyric Acid; Gene Expression; Hippocampus; Humans; Male; N-Methylaspartate; Ubiquitin-Protein Ligases

2009
Magnesium for treatment-resistant depression: a review and hypothesis.
    Medical hypotheses, 2010, Volume: 74, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; D-Aspartic Acid; Depression; Depressive Disorder; Depressive Disorder, Major; Fast Foods; Humans; Imipramine; Magnesium; Magnesium Deficiency; Mental Disorders; Models, Neurological; N-Methylaspartate; Randomized Controlled Trials as Topic; Suicide, Attempted

2010
New Evidence on the Role of D-Aspartate Metabolism in Regulating Brain and Endocrine System Physiology: From Preclinical Observations to Clinical Applications.
    International journal of molecular sciences, 2020, Nov-18, Volume: 21, Issue:22

    Topics: Animals; Brain; D-Aspartate Oxidase; D-Aspartic Acid; Growth Hormone; Humans; N-Methylaspartate; Neurosecretory Systems; Receptors, N-Methyl-D-Aspartate; Substrate Specificity

2020

Trials

1 trial(s) available for d-aspartic acid and n-methylaspartate

ArticleYear
Neuroprotective effects of amantadine for experimental acute carbon monoxide poisoning.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:19

    Topics: Amantadine; Animals; Antioxidants; Arginine; Carbon Monoxide; Carbon Monoxide Poisoning; Catalase; D-Aspartic Acid; Formaldehyde; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Paraffin; Rats; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase

2022

Other Studies

24 other study(ies) available for d-aspartic acid and n-methylaspartate

ArticleYear
The effect of D-aspartate on luteinizing hormone-releasing hormone, alpha-melanocyte-stimulating hormone, GABA and dopamine release.
    Neuroreport, 2002, Dec-03, Volume: 13, Issue:17

    Topics: alpha-MSH; Animals; D-Aspartic Acid; Dopamine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Male; N-Methylaspartate; Neural Pathways; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase; Pituitary Gland, Posterior; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2002
Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:6

    Topics: Alanine; Animals; Biguanides; Calcium Channel Blockers; Cattle; D-Aspartic Acid; Diltiazem; Dizocilpine Maleate; Drug Synergism; Glucose; Glutamic Acid; Glycine; Humans; Kainic Acid; N-Methylaspartate; Nitrendipine; omega-Conotoxins; Perfusion; Piperidines; Polyamines; Receptors, Glutamate; Retina; Tritium; Verapamil

2003
D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons.
    British journal of pharmacology, 2005, Volume: 145, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; D-Aspartic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Oocytes; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Complementary; Stereoisomerism; Xenopus laevis

2005
D-aspartate and reproductive activity in sheep.
    Theriogenology, 2006, Apr-15, Volume: 65, Issue:7

    Topics: Animals; Brain; D-Aspartic Acid; Endocrine Glands; Female; Lactation; Luteinizing Hormone; N-Methylaspartate; Organ Specificity; Pineal Gland; Pituitary Gland; Progesterone; Reproduction; Sexual Behavior, Animal; Sheep

2006
A physiological mechanism to regulate D-aspartic acid and NMDA levels in mammals revealed by D-aspartate oxidase deficient mice.
    Gene, 2006, Jun-07, Volume: 374

    Topics: Animals; D-Aspartate Oxidase; D-Aspartic Acid; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Library; Gene Targeting; Homozygote; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Tissue Distribution

2006
Effect of the L- or D-aspartate on ecto-5'nucleotidase activity and on cellular viability in cultured neurons: participation of the adenosine A(2A) receptors.
    Amino acids, 2007, Volume: 33, Issue:3

    Topics: 5'-Nucleotidase; Adenosine Monophosphate; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; D-Aspartic Acid; Glutamic Acid; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptor, Adenosine A2A

2007
HPLC determination of acidic D-amino acids and their N-methyl derivatives in biological tissues.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:6

    Topics: Aniline Compounds; Chromatography, High Pressure Liquid; D-Aspartic Acid; Glutamates; Isomerism; N-Methylaspartate; Sensitivity and Specificity; Time Factors; Valine

2009
Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors.
    Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:1

    Topics: Adult; Amyotrophic Lateral Sclerosis; Animals; Brain; D-Aspartic Acid; Functional Laterality; Humans; Japan; Kynurenic Acid; Kynurenine; Motor Neurons; N-Methylaspartate; Quinolinic Acid; Riluzole; Signal Transduction; Tryptophan

2009
Activation of presynaptic alpha7 nicotinic receptors evokes an excitatory response in hippocampal CA3 neurones in anaesthetized rats: an in vivo iontophoretic study.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; D-Aspartic Acid; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Neurons; Nicotine; Nicotinic Antagonists; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Spiro Compounds

2010
Protective effects of the pyrolyzates derived from bamboo against neuronal damage and hematoaggregation.
    Journal of ethnopharmacology, 2010, Apr-21, Volume: 128, Issue:3

    Topics: Animals; Apoptosis; Bambusa; Cell Death; Cell Survival; Cerebral Cortex; China; D-Aspartic Acid; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley

2010
Growth hormone rescues hippocampal synaptic function after sleep deprivation.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:6

    Topics: Animals; D-Aspartic Acid; Glutamic Acid; Growth Hormone; Hippocampus; Long-Term Potentiation; Male; Memory; N-Methylaspartate; Neurons; Protein Subunits; Rats; Rats, Sprague-Dawley; Signal Transduction; Sleep Deprivation

2010
Methionine choline reverses lead-induced cognitive and N-methyl-d-aspartate receptor subunit 1 deficits.
    Toxicology, 2010, Jun-04, Volume: 272, Issue:1-3

    Topics: Animals; Brain; Choline; Cognition Disorders; D-Aspartic Acid; Hippocampus; Male; Memory; Methionine; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; RNA, Messenger

2010
Inhibition of brown adipose tissue thermogenesis by neurons in the ventrolateral medulla and in the nucleus tractus solitarius.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:1

    Topics: Adipose Tissue, Brown; Animals; Bicuculline; Body Temperature; Cardiovascular System; Cold Temperature; D-Aspartic Acid; Fever; Hypothalamus; Male; Medulla Oblongata; Muscimol; N-Methylaspartate; Neurons; Preoptic Area; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Thermogenesis

2010
Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Apoptosis Inducing Factor; Caspases; Cell Death; D-Aspartic Acid; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Inhibitors; Female; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Reperfusion; Stroke

2010
Interaction of PGHS-2 and glutamatergic mechanisms controlling the ovine fetal hypothalamus-pituitary-adrenal axis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:1

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; D-Aspartic Acid; Female; Fetus; Hydrocortisone; Hypothalamus; Isoenzymes; N-Methylaspartate; Neurosecretory Systems; Parturition; Pituitary-Adrenal System; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Resveratrol; Sheep; Stilbenes; Sulfonamides

2010
Pax2 is expressed in a subpopulation of Müller cells in the central chick retina.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2010, Volume: 239, Issue:6

    Topics: Animals; Cells; Chick Embryo; D-Aspartic Acid; Embryo, Nonmammalian; N-Methylaspartate; Neuroglia; PAX2 Transcription Factor; Retina

2010
Hippocampal AMPA autoreceptors positively coupled to NMDA autoreceptors traffic in a constitutive manner and undergo adaptative changes following enriched environment training.
    Neuropharmacology, 2011, Volume: 61, Issue:8

    Topics: Adaptation, Physiological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzothiadiazines; Carrier Proteins; Cytoskeletal Proteins; D-Aspartic Acid; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Environment; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Guanylate Kinases; Hippocampus; Immunoprecipitation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; N-Ethylmaleimide-Sensitive Proteins; N-Methylaspartate; Nuclear Proteins; Presynaptic Terminals; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptophysin; Synaptosomes; Tritium

2011
Higher free D-aspartate and N-methyl-D-aspartate levels prevent striatal depotentiation and anticipate L-DOPA-induced dyskinesia.
    Experimental neurology, 2011, Volume: 232, Issue:2

    Topics: Action Potentials; Animals; Antiparkinson Agents; Corpus Striatum; D-Aspartate Oxidase; D-Aspartic Acid; Dyskinesia, Drug-Induced; Extracellular Signal-Regulated MAP Kinases; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuronal Plasticity; Oxidopamine; Parkinsonian Disorders; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sympatholytics; Synapses

2011
HPLC methods for determination of D-aspartate and N-methyl-D-aspartate.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 794

    Topics: Calibration; Chromatography, High Pressure Liquid; D-Aspartic Acid; N-Methylaspartate; Spectrometry, Fluorescence

2012
N-methyl-D-aspartate preconditioning prevents quinolinic acid-induced deregulation of glutamate and calcium homeostasis in mice hippocampus.
    Neurotoxicity research, 2015, Volume: 27, Issue:2

    Topics: Animals; Calcium; D-Aspartic Acid; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Homeostasis; Male; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Quinolinic Acid; Seizures

2015
Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:2

    Topics: Animals; Cell Line; D-Aspartate Oxidase; D-Aspartic Acid; Humans; Hydrogen-Ion Concentration; Mice; Models, Molecular; N-Methylaspartate; Protein Conformation; Rats; Recombinant Proteins; Temperature

2015
Ketogenic diet attenuates NMDA-induced damage to rat's retinal ganglion cells in an age-dependent manner.
    Ophthalmic research, 2015, Volume: 53, Issue:3

    Topics: Animals; Cell Count; D-Aspartic Acid; Diet Therapy; Diet, Ketogenic; Disease Models, Animal; Female; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Inbred BN; Retinal Degeneration; Retinal Ganglion Cells

2015
d-aspartate and N-methyl-d-aspartate promote proliferative activity in mouse spermatocyte GC-2 cells.
    Reproductive biology, 2022, Volume: 22, Issue:1

    Topics: Animals; D-Aspartic Acid; Male; Mice; N-Methylaspartate; Spermatocytes; Spermatogenesis; Spermatogonia

2022
Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain.
    Cells, 2022, 12-13, Volume: 11, Issue:24

    Topics: Animals; Cognition; D-Aspartic Acid; Depression; Glutamic Acid; N-Methylaspartate; Neuralgia; Rats

2022