d-alpha tocopherol has been researched along with tocotrienols in 287 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.70) | 18.7374 |
| 1990's | 21 (7.32) | 18.2507 |
| 2000's | 96 (33.45) | 29.6817 |
| 2010's | 123 (42.86) | 24.3611 |
| 2020's | 45 (15.68) | 2.80 |
| Authors | Studies |
|---|---|
| Deason, ME; Parker, RA; Pearce, BC; Qureshi, AA; Wright, JJ | 1 |
| Han, D; Kagan, V; Packer, L; Serbinova, E | 1 |
| Heinonen, M; Piironen, V | 1 |
| Weimann, BJ; Weiser, H | 1 |
| Iizuka, K; Komiyama, K; Tsuchiya, N; Umezawa, I; Watanabe, H; Yamaoka, M | 1 |
| Koivistoinen, P; Piironen, V; Salminen, K; Syväoja, EL; Varo, P | 1 |
| Järvinen, R | 1 |
| Komiyama, K; Yamaoka, M | 1 |
| Packer, L; Serbinova, EA | 1 |
| Khalid, BA; Ong, FB; Shamaan, NA; Top, AG; Wan Ngah, WZ | 1 |
| Choo, YM; Govil, G; Kagan, VE; Packer, L; Suzuki, YJ; Tsuchiya, M; Wassall, SR | 1 |
| Dean, RT; Hood, RL; Stocker, R; Suarna, C | 1 |
| Hofer, PJ; Jackson, LL; Newman, CW; Newman, RK; Wang, L | 1 |
| Devasagayam, TP; Kamat, JP | 2 |
| Ikeda, I; Imasato, Y; Sasaki, E; Sugano, M | 1 |
| Adam, A; Marzuki, A; Ngah, WZ; Top, GM | 1 |
| Carroll, KK; Chambers, AF; Gapor, A; Guthrie, N | 1 |
| Basiron, Y; Devasagayam, TP; Kamat, JP; Nesaretnam, K; Sarma, HD | 1 |
| Maibach, HI; Packer, L; Podda, M; Rallis, M; Traber, MG; Weber, C | 1 |
| Darbre, P; Dils, R; Nesaretnam, K; Stephen, R | 1 |
| Speake, BK; Surai, PF | 1 |
| Gapor, A; Kline, K; Sanders, BG; Simmons-Menchaca, M; Yu, W | 1 |
| Addis, PB; Katsanidis, E | 1 |
| Briski, KP; Fariss, MW; Gapor, A; McIntyre, BS; Sylvester, PW; Tirmenstein, MA | 1 |
| Khanna, S; Packer, L; Roy, S; Sen, CK | 1 |
| Adachi, H; Ishii, N | 1 |
| Ikeda, S; Niwa, T; Yamashita, K | 1 |
| Black, TM; Coleman, RA; Maeda, N; Wang, P | 1 |
| Packer, L; Rimbach, G; Weber, SU | 1 |
| Wong, JW; Yap, SP; Yuen, KH | 1 |
| Leonard, S; Lodge, JK; Ridlington, J; Traber, MG; Vaule, H | 1 |
| German, B; Kaushik, S; Leonard, S; Traber, MG; Wander, R | 1 |
| Drotleff, AM; Ternes, W | 1 |
| Furukawa, F; Hirose, M; Imazawa, T; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY | 1 |
| Böhme, T; Goffman, FD | 1 |
| Ikeda, S; Toyoshima, K; Yamashita, K | 1 |
| Briski, KP; Gapor, A; McIntyre, BS; Sylvester, PW | 1 |
| Chao, JT; Gapor, A; Theriault, A | 2 |
| Aebischer, C; Elste, V; Raederstorff, D; Weber, P | 1 |
| Begum, AN; Terao, J | 1 |
| Nor, RM; Sundram, K | 1 |
| Iizuka, Y; Ikeda, I; Ikeda, S; Yamashita, K | 1 |
| Khanna, S; Roy, S; Sen, CK; Venojarvi, M | 1 |
| DeMichele, SJ; Edens, NK; Mustad, VA; Ruey, PP; Smith, CA | 1 |
| Han, N; Luu, C; Packer, L; Thiele, JJ; Valacchi, G; Weber, S; Weber, SU | 1 |
| Egashira, N; Fujiwara, M; Hidaka, R; Iwasaki, K; Karube, Y; Matsunaga, K; Mishima, K; Pu, F; Takata, J; Tanaka, T | 1 |
| Fuchs, J; Groth, N; Herrling, T; Kaufmann, R; Packer, L; Podda, M; Weber, S | 1 |
| Abe, K; Hamamura, K; Ikeda, S; Tohyama, T; Yamashita, K; Yoshimura, H | 1 |
| Lim, AB; Yap, SP; Yuen, KH | 1 |
| Anderson, SL; Qiu, J; Rubin, BY | 1 |
| Hanyu, R; Kodama, T; Noguchi, N; Nonaka, A; Okimoto, Y | 1 |
| Cahoon, EB; Coughlan, SJ; Ganzke, TS; Hall, SE; Hitz, WD; Ripp, KG | 1 |
| Bahadduri, P; Khanna, S; Ratan, RR; Roy, S; Ryu, H; Sen, CK; Swaan, PW | 1 |
| Dörmann, P | 1 |
| Hari, SP; Huang, D; Naguib, Y; Passwater, R | 1 |
| Dubald, M; Matringe, M; Rippert, P; Scimemi, C | 1 |
| Ajjawi, I; Shintani, D | 1 |
| Block, G; Dietrich, M; Hudes, M; Jensen, C; Norkus, EP; Packer, L | 1 |
| Ima-Nirwana, S; Suhaniza, S | 1 |
| Yap, SP; Yuen, KH | 1 |
| Friedrich, MJ | 1 |
| Hayakawa, M; Itoh, N; Niki, E; Ohira, A; Tanito, M; Yoshida, Y | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Osakada, F | 1 |
| Shah, SJ; Sylvester, PW | 1 |
| Brigelius-Flohé, R; Bumke-Vogt, C; Kluth, D; Landes, N; Pfluger, P | 1 |
| Choo, YM; Chuah, CH; Hashim, MA; Ma, AN; Ng, MH | 1 |
| McCormick, CC; Parker, RS; Sontag, TJ; Swanson, JE | 1 |
| Stocker, A | 1 |
| Khanna, S; Roy, S; Sen, CK | 2 |
| Hayakawa, M; Niki, E; Nishio, K; Saito, Y; Yoshida, Y | 1 |
| Parker, RS; Sontag, TJ | 2 |
| Ichikawa, H; Katada, K; Kokura, S; Kuroda, M; Manabe, H; Naito, Y; Nakabe, N; Noguchi, N; Shimozawa, M; Yoshida, N; Yoshikawa, T | 1 |
| Chua, CW; Ima-Nirwana, S; Norazlina, M | 1 |
| Azzi, A; Frueh, BE; Goldblum, D; Kilchenmann, M; Meyenberg, A; Nesaretnam, K; Zingg, JM | 1 |
| Alves, MR; Amaral, JS; Oliveira, BP; Seabra, RM | 1 |
| Qi, Q; Valentin, HE | 1 |
| Cynshi, O; Hayakawa, M; Itoh, N; Jishage, K; Niki, E; Piga, R; Yoshida, Y | 1 |
| Chaki, S; Craft, TK; DeVries, AC; Khanna, S; Notestine, MA; Parinandi, NL; Rink, C; Roy, S; Sen, CK; Slivka, A | 1 |
| Ahmad, NS; Ima Nirwana, S; Khalid, BA; Luke, DA | 1 |
| Khanna, S; Patel, V; Rink, C; Roy, S; Sen, CK | 1 |
| Bakirci, H; Nau, WM; Netscher, T; Sonnen, AF | 1 |
| Okabe, M; Sakai, M; Tachibana, H; Yamada, K | 1 |
| Chênevert, R; Courchesne, G; Pelchat, N | 1 |
| Kumamaru, E; Kunugi, H; Matsumoto, T; Niki, E; Numakawa, T; Numakawa, Y; Taguchi, T; Yagasaki, Y | 1 |
| Collins, JJ; Evason, K; Kornfeld, K | 1 |
| Khanna, S; Maurer, M; Parinandi, NL; Roy, S; Sen, CK | 1 |
| Gapor, A; Qureshi, AA; Qureshi, N; Tan, B; Thomas, AM; Yu, SG | 1 |
| Ezziddin, O; Khanna, S; Patel, V; Roy, S; Sen, CK | 1 |
| Cheng, HM; Fairus, S; Nor, RM; Sundram, K | 2 |
| Abe, C; Ichikawa, T; Ikeda, S; Uchida, T; Yamashita, K | 1 |
| Kawakami, Y; Miyazawa, T; Nakagawa, K; Tsuzuki, T | 1 |
| Rahman, AR; Rasool, AH; Wong, AR; Yuen, KH; Yusoff, K | 1 |
| Avanzi, L; Bravo, E; Manfredini, S; Napolitano, M | 1 |
| Ima-Nirwana, S; Lee, PL; Lukman, HI; Nazrun, AS; Norazlina, M | 1 |
| Ajuluchukwu, JN; Fasanmade, OA; Mabayoje, M; Mbakwem, AC; Ojini, FI; Oke, DA; Okubadejo, NU; Okwudiafor, RN | 1 |
| Cahoon, EB; Hunter, SC | 1 |
| Khanna, S; Rink, C; Roy, S; Sen, CK | 1 |
| Courtet-Compondu, MC; Holst, B; Kussmann, M; Nagy, K | 1 |
| Gomez, PA; Nesaretnam, K; Razak, GA; Selvaduray, KR | 1 |
| Kruk, J; Szymańska, R | 1 |
| Massone, S; Munteanu, A; Ricciarelli, R; Zingg, JM | 1 |
| Boesch-Saadatmandi, Ch; Huebbe, P; Jofre-Monseny, L; Minihane, AM; Rimbach, G | 1 |
| Ishikawa, T; Kiso, Y; Obayashi, M; Ono, Y; Yamada, Y; Yamashita, K | 1 |
| Maniam, S; Mohamed, N; Shuid, AN; Soelaiman, IN | 1 |
| Atkinson, J; Nava, P; Ohnmacht, S; Parker, R; West, R | 1 |
| Aung, H; Kaur, J; Lee, AL; Nesaretnam, K; Radhakrishnan, AK; Wong, PF | 1 |
| Nakano, M; Nguyen, VC; Onodera, A; Saito, E; Takahashi, J; Tanabe, M; Yajima, K | 1 |
| Rahman, AR; Rasool, AH; Wong, AR; Yuen, KH | 1 |
| Nafeeza, MI; Nur Azlina, MF | 1 |
| Freiser, H; Jiang, Q | 1 |
| Bishnoi, M; Chopra, K; Kuhad, A; Tiwari, V | 1 |
| Chopra, K; Kuhad, A; Tiwari, V | 2 |
| Alves, RC; Barreira, JC; Casal, S; Ferreira, IC; Oliveira, MB; Pereira, JA | 1 |
| Abdul Hafid, SR; Cheng, HM; Nesaretnam, K; Yam, ML | 1 |
| Chopra, K; Gupta, A | 1 |
| Bibus, D; Khanna, S; Kotha, SR; Parinandi, NL; Rink, C; Roy, S; Sen, CK | 1 |
| DellaPenna, D; Mène-Saffrané, L | 1 |
| Gogvadze, V; Norberg, E; Orrenius, S; Zhivotovsky, B | 1 |
| Kang, Z; Li, F; Tan, W; Wong, CW | 1 |
| Ng, LT; Wu, SJ | 1 |
| Galli, F; Pierpaoli, E; Pilolli, F; Piroddi, M; Provinciali, M; Viola, V | 1 |
| Ali, H; El-Sayed, K; Nazzal, S; Sylvester, PW | 1 |
| Böhm, V; Müller, L; Theile, K | 1 |
| Falk, J; Munné-Bosch, S | 1 |
| Muharis, SP; Murugan, D; Mustafa, MR; Top, AG | 1 |
| Colombo, ML | 1 |
| Das, S; Fatimah, IS; Khairul, O; Lee, CC; Mohamad, J; Poh, BK; Zahara, AM | 1 |
| Aggarwal, BB; Kannappan, R; Prasad, S; Sundaram, C | 1 |
| Akazawa, YO; Miyama, A; Niki, E; Nishio, K; Noguchi, N; Saito, Y; Yamanaka, K; Yoshida, Y | 1 |
| Bardowell, SA; Parker, RS; Stec, DE | 1 |
| Borgschulte, T; Cahoon, EB; Cahoon, RE; Han, J; Hunter, SC; Yang, W; Zhang, C | 1 |
| Ha, H; Kim, HN; Lee, JH; Lee, ZH | 1 |
| Folts, JD; Karpen, CW; Morrison, DC; Papasian, CJ; Qureshi, AA; Qureshi, N | 1 |
| Checker, R; Devasagayam, TP; Khan, NM; Patil, A; Patwardhan, R; Sandur, SK; Sharma, D; Wilankar, C | 1 |
| Amagata, A; Barnes, A; Enns, GM; Hinman, A; Jankowski, O; Kheifets, V; Komatsuzaki, R; Lee, E; Miller, G; Mollard, P; Murase, K; Sadun, AA; Shrader, WD; Thoolen, M; Wesson, K | 1 |
| Chan, YC; Gnyawali, S; Khanna, S; Kubicki, N; Park, HA; Roy, S; Sen, CK | 1 |
| Abdullah, M; Ramasamy, R; Tan, SW; Vidyadaran, S | 1 |
| Du, YQ; Gao, J; Gong, YF; Gu, JJ; Hu, LH; Jiang, F; Li, ZS; Liao, Z; Man, XH | 1 |
| Khanna, S; Patel, V; Rink, C; Sen, CK | 1 |
| Abe, C; Ichikawa, T; Ikeda, S; Nomura, S; Uchida, T | 2 |
| Fukui, K; Koike, T; Takatsu, H; Urano, S; Ushiki, K | 1 |
| Constantinou, AI; Constantinou, C; Hyatt, JA; Neophytou, CM; Papas, KA; Vraka, P | 1 |
| Chiocca, EA; Elkhammas, EA; Firstenberg, MS; Ganesh, K; Gnyawali, U; Gordillo, GM; Khanna, S; Kirkpatrick, R; Klatte, E; Miller, M; More, JL; Nesaretnam, K; Patel, V; Phillips, G; Rink, C; Roy, S; Sarkar, A; Sen, CK; Shneker, B | 1 |
| Kaup, RM; Khayyal, MT; Verspohl, EJ | 1 |
| Cheong, SK; Ibrahim, TA; Radhakrishnan, AK; Wong, RS | 1 |
| Brown, AJ; Krycer, JR; Phan, L | 1 |
| Li, Y; Liang, GH; Liu, QQ; Liu, RR; Tang, KX; Xu, G; Zhang, GY; Zhang, P | 1 |
| Hirahara, Y; Homma, S; Inoue, T; Muranaka, N; Nakane, T; Nomi, Y; Otsuka, Y; Takano, A; Tatemori, S | 1 |
| Radhakrishnan, AK; Wong, RS | 1 |
| Barreira, JC; Casal, S; Ferreira, IC; Oliveira, MB; Pereira, JA; Peres, AM | 1 |
| Kawakami, Y; Kimura, F; Kimura, T; Kobayashi, T; Komai, M; Miyazawa, T; Nakagawa, K; Ohashi, A; Ohsaki, Y; Sato, S; Shibata, A; Shirakawa, H; Takashima, R; Tsuduki, T | 1 |
| Ko, HJ; Ng, LT | 1 |
| Cahoon, EB; Cahoon, RE; Chen, M; Han, J; Hunter, SC; Zhang, C | 1 |
| Niki, E; Traber, MG | 1 |
| Alayoubi, A; Anderson, JF; Kanthala, S; Nazzal, S; Satyanarayanajois, SD; Sylvester, PW | 1 |
| Ayoub, NM; Sylvester, PW | 1 |
| Baglioni, M; Cecchetti, R; Floridi, P; Gobbi, G; Kivipelto, M; Kłoszewska, I; Lovestone, S; Mangialasche, F; Mecocci, P; Muehlboeck, JS; Simmons, A; Soininen, H; Spenger, C; Tarducci, R; Tsolaki, M; Vellas, B; Wahlund, LO; Westman, E | 1 |
| Loganathan, R; Nesaretnam, K; Radhakrishnan, AK; Selvaduray, KR | 1 |
| Beattie, LA; Seed, TM; Singh, VK | 1 |
| Hanzawa, F; Ikeda, S; Nomura, S; Sakuma, E; Uchida, T | 1 |
| Birringer, M; Ciobanu, I; Eckert, GP; Eckert, SH; El-Askary, H; Frank, J; Hagl, S; Helal, A; Khayyal, MT; Kocher, A; Muller, WE; Schiborr, C | 1 |
| Cardenas, E; Ghosh, R | 1 |
| Cela, J; Munné-Bosch, S; Siles, L | 1 |
| Jung, NY; Lee, BH; Lee, KH; Won, R | 1 |
| Cecchetti, R; Fratiglioni, L; Hooshmand, B; Kåreholt, I; Kivipelto, M; Laatikainen, T; Mangialasche, F; Mecocci, P; Soininen, H; Solomon, A | 1 |
| Abu Bakar, MR; Ansari, MA; Gopalan, Y; Khan, NA; Magosso, E; Ng, BH; Shuaib, IL; Wong, JW; Yuen, KH | 1 |
| Ismail, Z; Jam, FA; Khor, SC; Makpol, S; Rahim, NA; Wan Ngah, WZ; Yusof, YA | 1 |
| Boerma, M; Breen, PJ; Compadre, CM; Ghosh, S; Hauer-Jensen, M; Kiaei, M; Singh, A; Thakkar, S; Varughese, KI; Zheng, G | 1 |
| Ghazali, HM; Muhammad, K; Ramakrishnan, Y; Shammugasamy, B | 1 |
| Abd Latiff, A; Abd Rani, N; Mazlan, M; Ngah, WZ; Taridi, NM | 1 |
| Gerling, EM; Ternes, W | 1 |
| Ishikawa, E; Izumisawa, K; Koike, T; Mukai, K; Nagaoka, S; Ouchi, A; Suzuki, T | 1 |
| Bobe, G; Lansky, EP; Nevo, E; Shen, Y; Traber, MG; Watts, EJ | 1 |
| Harvey, KA; Pavlina, TM; Siddiqui, RA; Xu, Z; Zaloga, GP | 1 |
| Bunzel, D; Knecht, K; Kulling, SE; Sandfuchs, K | 1 |
| Abd Mutalib, MS; Khaza'ai, H; Selvaraju, TR; Vasudevan, R; Vidyadaran, S | 1 |
| Bradshaw, TD; Lim, SW; Loh, HS; Ting, KN; Zeenathul, NA | 1 |
| Dolde, D; Hansen, H; Prusa, K; Wang, T; Xin, H | 1 |
| Bicalho, EM; Garcia, QS; Morales, M; Müller, M; Munné-Bosch, S; Pintó-Marijuan, M | 1 |
| Abdul Rahman Sazli, F; Abdul Rahman, M; Jubri, Z; Karsani, SA; Md Top, AG; Wan Ngah, WZ | 1 |
| Khor, SC; Makpol, S; Mohd Yusof, YA; Wan Ngah, WZ | 1 |
| Able, AJ; Box, A; Cozzolino, D; Do, TD; Muhlhausler, B | 1 |
| Baik, JY; Kim, IH; Kim, NH; Kwak, J; Lee, JS; Yoon, MR; Yoon, SW | 1 |
| Ali, SF; Woodman, OL | 1 |
| Hamdan, Y; Khaza'ai, H; Ramachandran, V; Rati Selvaraju, T; Sokhini Abd Mutalib, M; Vidyadaran, S | 1 |
| Dänicke, S; Frank, J; Meyer, U; Rehage, J; Sadri, H; Sauerwein, H | 1 |
| Alegre, L; Munné-Bosch, S; Siles, L; Tijero, V | 1 |
| Bhoo-Pathy, N; Chik, Z; Choudhury, RB; Fuang, HG; Jabir, RS; Meganathan, P; Nesaretnam, K; Taib, NA | 1 |
| Büsing, A; Drotleff, AM; Empl, MT; Steinberg, P; Ternes, W; Willenberg, I | 1 |
| Brown, L; Fong, CW; Ward, LC; Wong, WY; Yap, WN | 1 |
| Gay, MC; Gee, PT; Liew, CY; Thong, MC | 1 |
| Bao, J; Beta, T; Li, G; Li, M; Xu, F; Yu, L | 1 |
| Sato, A; Sato, C; Shiozawa, S; Sugahara, R; Uchida, A; Virgona, N; Yano, T | 1 |
| Abdul Karim, N; Khor, SC; Makpol, S; Mohd Yusof, YA; Razak, AM; Wan Ngah, WZ | 1 |
| Miyanoki, Y; Nakazawa, T; Noguchi, N; Saito, Y; Uehara, M; Urano, Y | 1 |
| Bachri, A; Binz, RK; Boerma, M; Ghosh, SP; Hauer-Jensen, M; Koturbash, I; Pathak, R; Sawyer, JR | 1 |
| Kawakami, Y; Kimura, T; Miyazawa, T; Nakagawa, K; Shibata, A | 1 |
| Kruk, J; Nowicka, B; Szymańska, R | 1 |
| Che, HL; Kanthimathi, MS; Loganathan, R; Nesaretnam, K; Selvaduray, KR; Tan, AT; Teng, KT; Yuen, KH | 1 |
| Endres, K; Grimm, HS; Grimm, MO; Hartmann, T; Mett, J; Nelke, C; Regner, L; Schorr, P; Stahlmann, CP; Stoetzel, H; Streidenberger, O; Thiel, A; Volmer, DA; Winkler, J; Zaidan, SR | 1 |
| Abu-Fayyad, A; Nazzal, S | 2 |
| Chuah, LH; De Silva, L; Fu, JY; Htar, TT; Tan, DM | 1 |
| Iwaniec, UT; Leonard, SW; Tennant, KG; Traber, MG; Turner, RT; Wong, CP | 1 |
| Beretta, G; Fontana, F; Gelmini, F; Limonta, P; Montagnani Marelli, M; Moretti, RM | 1 |
| Jia, CH; Kim, YM; Lee, KT; Shin, JA | 1 |
| Asai, A; Eitsuka, T; Kobayashi, T; Miyazawa, T; Nakagawa, K; Oikawa, S; Shibata, A | 1 |
| Chia, LL; Chua, KH; Jantan, I | 1 |
| Kushairi, A; Ng, MH | 1 |
| Bradbury, PJ; Buckler, ES; Buell, CR; Cepela, J; DellaPenna, D; Diepenbrock, CH; Góngora-Castillo, E; Gore, MA; Hamilton, J; Ilut, DC; Kandianis, CB; Lipka, AE; Magallanes-Lundback, M; Mateos-Hernandez, M; Mesberg, A; Owens, BF; Rocheford, T; Tiede, T; Vaillancourt, B; Wallace, JG | 1 |
| Abdullah, SNA; Babura, SR; Khaza Ai, H | 1 |
| Bory, A; Chabert, V; Chaisse-Leal, L; Doan, AV; Frey, L; Fromm, KM; Gust, A; Mène-Saffrané, L; Pellaud, S; Romanens, J | 1 |
| Abu-Fayyad, A; Cardelli, J; Carroll, JL; Cody, R; Dragoi, AM; Kamal, MM; Nazzal, S | 1 |
| Khan, DA; Mushtaq, S; Qureshi, AA; Qureshi, N; Silswal, N; Zuvanich, EG | 1 |
| Abraham, A; Kattoor, AJ; Mehta, JL; Saldeen, T | 1 |
| Abdullah, A; Jaafar, F; Makpol, S | 1 |
| Abdul Ghani, SM; Goon, JA; Hamid, Z; Nor Azman, NHE; Wan Ngah, WZ | 1 |
| Caccia, C; Cherkaoui-Malki, M; Leoni, V; Lizard, G; Meddeb, W; Ménétrier, F; Mihoubi, W; Moreau, T; Namsi, A; Nury, T; Riedinger, JM; Sassi, K; Sghaier, R; Uzun, T; Vejux, A; Zarrouk, A | 1 |
| Flory, S; Frank, J; Irías-Mata, A; Podszun, M; Stock, D; Sus, N; Woerner, D | 1 |
| Alegre, L; Cahoon, EB; González-Solís, A; Munné-Bosch, S; Siles, L | 1 |
| B Lajis, AF; Cheah, YK; Chong, WT; Habi Mat Dian, NL; Kanagaratnam, S; Lai, OM; Tan, CP | 1 |
| Benešová, K; Cerkal, R; Granda, L; Neuwirthová, J; Pluháčková, H; Rosero, A | 1 |
| Jiang, Q | 2 |
| Aykin-Burns, N; Boerma, M; Hauer-Jensen, M; Kim, T; Pathak, R | 1 |
| Lee, MJ; Lin, Y; Liu, AB; Ran, L; Xie, P; Yang, CS | 1 |
| Azman, NHEN; Ghani, SMA; Goon, JA; Hamid, Z; Ngah, WZW; Zakaria, SNA | 1 |
| Charalambous, C; Constantinou, C; Kanakis, D | 1 |
| Fen, LS; Jamal, R; Makpol, S; Wan Ngah, WZ; Yusof, KM | 1 |
| Szymańska, R; Trela, A | 1 |
| Azzi, A | 2 |
| Che, LM; Xie, QF; Zhang, LX; Zhang, ZS | 1 |
| Munné-Bosch, S; Muñoz, P | 1 |
| Di Vincenzo, A; El Hadi, H; Pagano, C; Rossato, M; Tana, C; Vettor, R | 1 |
| Kogure, K | 1 |
| Matsura, T | 1 |
| Chang, SK; Khaza'ai, H; Radhakrishnan, AK; Rahim, AA; Zainal, Z | 1 |
| Bian, H; Buerte, B; Chen, J; Han, N; Liu, C; Tang, Y; Wang, J; Wang, M; Yang, Y; Zeng, Z; Zhang, Y; Zhou, C; Zhu, M | 1 |
| Aoki, Y; Fukui, K; Kato, Y | 1 |
| Charalambous, C; Constantinou, AI; Constantinou, C; Kanakis, D; Kolokotroni, O | 1 |
| Duary, RK; Gautam, G; Gupta, K; Mahanta, CL | 1 |
| Israf Ali, DAB; Khaza'ai, H; Tan, SW; Vidyadaran, S; Wong, JW | 1 |
| Abd Hamid, R; Chang, SK; Chiroma, AA; Khaza'ai, H; Zainal, Z; Zakaria, ZA | 1 |
| Cai, Z; Huang, B; Xu, J; Zhang, J; Zheng, Y | 1 |
| Aoki, Y; Beppu, F; Gotoh, N; Kasatani, S; Sakuma, A | 1 |
| Chin, KY; Ima-Nirwana, S; Leong, XF; Shadisvaaran, S; Shahida, MS | 1 |
| Chojnacka, A; Górnicka, M; Szewczyk, K | 1 |
| Hu, G; Lu, H; Shen, W; Wang, H; Wei, X; Wu, B; Yu, K | 1 |
| Antoszczak, M; Huczyński, A; Markowska, A; Markowska, J | 1 |
| Hernandez, F; Tkacz, K; Turkiewicz, IP; Wojdyło, A | 1 |
| de Camargo, AC; Fuentes, J; Pinaffi-Langley, ACC; Shahidi, F; Speisky, H | 1 |
| Im, S; Jiang, Q; Park, NY | 1 |
| Brigelius-Flohé, R | 1 |
| Abdul Kadir, K; Ahmad, B; Botross Henien, NP; Chuar, PF; Ho, JI; Ho, LS; Koay, YY; Ng, YT; Phang, SCW | 1 |
| Bhuvanendran, S; Khalid, AQ; Kumari, M; Magalingam, KB; Radhakrishnan, AK; Ramdas, P | 1 |
| Carnevale, R; Loffredo, L; Nocella, C; Pignatelli, P; Violi, F | 1 |
| Büntzel, J; Dörfler, J; Freuding, M; Hübner, J; Kutschan, S; Retzlaff, D | 1 |
| Liu, Y; Zaaboul, F | 1 |
| Fujiwara, Y; Ichi, I; Ishikawa, T; Ko, Y; Sonoda, M | 1 |
| Hakamata, H; Kotani, A; Machida, K; Nishimura, T; Yamamoto, K | 1 |
| Chang, SK; Khaza'ai, H; Kutty Radhakrishnan, A; Zainal, Z | 1 |
| Mathai, M; Ranasinghe, R; Zulli, A | 1 |
| Baškirovs, G; Górnaś, P; Siger, A | 1 |
| Abd Ghafar, N; Chin, KY; Foong, LC; Law, JX; Leong, LM; Pang, KL; Soelaiman, IN | 1 |
| Bhuvanendran, S; Magalingam, KB; Radhakrishnan, AK; Ramdas, P; Selvaduray, KR; Somanath, SD | 1 |
| Nakatani, Y; Noguchi, N; Shimokawa, N; Takagi, M; Urano, Y | 1 |
| Carneiro da Silva, FC; de Castro E Sousa, JM; de Oliveira, KGF; de Oliveira, VA; de Sousa Coelho, MDPS; Dos Santos Rizzo, M; Oliveira, IKF; Pereira, IC; Torres-Leal, FL | 1 |
| Chew, DCH; Chin, KY; Ekeuku, SO; Trias, A | 1 |
| Xie, L; Yan, J | 1 |
| Eitsuka, T; Horikoshi, Y; Itaya-Takahashi, M; Jutanom, M; Matsura, T; Nakagawa, K; Nakatomi, T; Parida, IS; Shimizu, N; Tanaka, Y; Zingg, JM | 1 |
| Bian, Q; Feng, T; Jiao, X; Lyu, X; Ye, L; Yu, H | 1 |
| Fu, JY; Gunasegaran, N; Meganathan, P; Tan, DMY | 1 |
| Chia, SE; Kishida, R; Loh, WQ; Ong, CN; Seow, WJ; Yin, X | 1 |
| Aryusuk, K; Chumsantea, S; Jiruttisakul, A; Nakornsadet, A; Sombutsuwan, P | 1 |
| Cahoon, EB; Cahoon, RE; Gelli, M; Konda, AR; Obata, T; Pedersen, C; Zhang, C | 1 |
| Atkinson, J; Azzi, A; Galli, F; Manor, D; Ozer, NK; Wallert, M | 1 |
| Jopek, Z; Kutyła, A; Namo Ombugadu, J; Pawlak, K; Święcicka-Füchsel, E; Wojciechowski, K | 1 |
| Górnicka, M; Szewczyk, K | 1 |
| Białek, A; Białek, M; Czauderna, M; Wojtak, W | 1 |
49 review(s) available for d-alpha tocopherol and tocotrienols
| Article | Year |
|---|---|
Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling.
Topics: Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Antioxidants; Biological Availability; Cholesterol; Humans; Hydroxymethylglutaryl CoA Reductases; Intestinal Absorption; Lipoproteins, LDL; Oxidation-Reduction; Oxidative Stress; Protein Isoforms; Signal Transduction; Tissue Distribution; Tocotrienols; Vitamin E | 2001 |
Engineered plants with elevated vitamin E: a nutraceutical success story.
Topics: Alkyl and Aryl Transferases; Antioxidants; Enzymes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Engineering; Humans; Molecular Structure; Plants, Edible; Plants, Genetically Modified; Tocopherols; Tocotrienols; Vitamin E | 2004 |
Mechanisms mediating the antiproliferative and apoptotic effects of vitamin E in mammary cancer cells.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Humans; Mammary Neoplasms, Animal; Tocotrienols; Vitamin E | 2005 |
Vitamin E: underestimated as an antioxidant.
Topics: alpha-Tocopherol; Animals; Antioxidants; Fertility; gamma-Tocopherol; Humans; Models, Chemical; Oxidation-Reduction; Oxygen; Time Factors; Tocotrienols; Vitamin E | 2004 |
Discovery, characterization, and significance of the cytochrome P450 omega-hydroxylase pathway of vitamin E catabolism.
Topics: alpha-Tocopherol; Animals; Cytochrome P-450 CYP4A; gamma-Tocopherol; Humans; Microsomes, Liver; Oxidation-Reduction; Rats; Substrate Specificity; Tocotrienols; Vitamin E | 2004 |
Molecular mechanisms of vitamin E transport.
Topics: Animals; Binding Sites; Biological Transport; Carrier Proteins; Humans; Intestinal Absorption; Lipoproteins; Models, Molecular; Structure-Activity Relationship; Tocopherols; Tocotrienols; Trans-Activators; Vitamin E | 2004 |
Tocotrienol: the natural vitamin E to defend the nervous system?
Topics: Animals; Arachidonate 12-Lipoxygenase; Brain; Cell Death; CSK Tyrosine-Protein Kinase; Diet; Dietary Supplements; Gene Expression; Glutamic Acid; Humans; Nervous System Physiological Phenomena; Neurons; Protein-Tyrosine Kinases; src-Family Kinases; Tocotrienols; Vitamin E | 2004 |
Biotechnological production and application of vitamin E: current state and prospects.
Topics: Animals; Bacteria; Biotechnology; Humans; Plants; Tocopherols; Tocotrienols; Vitamin E | 2005 |
Tocotrienols: Vitamin E beyond tocopherols.
Topics: Animals; Antioxidants; Humans; Tocotrienols; Vitamin E | 2006 |
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
Topics: Aging; Animals; Anticonvulsants; Antioxidants; Blueberry Plants; Caenorhabditis elegans; Ethosuximide; Ethylenediamines; Ginkgo biloba; Longevity; Organometallic Compounds; Plant Extracts; Resveratrol; Salicylates; Stilbenes; Tocotrienols; Trimethadione; Ubiquinone; Vitamin E | 2006 |
Enhancing vitamin E in oilseeds: unraveling tocopherol and tocotrienol biosynthesis.
Topics: Plant Oils; Seeds; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Tocotrienols: the emerging face of natural vitamin E.
Topics: Animals; Antioxidants; Humans; Tocotrienols; Vitamin E | 2007 |
[Occurrence and function of tocochromanols in plants, animals and men].
Topics: Animals; Antioxidants; Chromans; Free Radical Scavengers; Humans; Molecular Structure; Plants; Seeds; Signal Transduction; Tissue Distribution; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Biosynthesis, regulation and functions of tocochromanols in plants.
Topics: Antioxidants; Cyanobacteria; Gene Expression; Genes, Plant; Photosynthesis; Plants; Plants, Genetically Modified; Tocopherols; Tocotrienols; Vitamin E | 2010 |
Tocochromanol functions in plants: antioxidation and beyond.
Topics: Antioxidants; Plants; Tocopherols; Tocotrienols; Vitamin E | 2010 |
An update on vitamin E, tocopherol and tocotrienol-perspectives.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Humans; Neoplasms; Tocopherols; Tocotrienols; Vitamin E; Vitamins | 2010 |
Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases.
Topics: Animals; Antineoplastic Agents; Antioxidants; Chronic Disease; Drug Delivery Systems; Humans; Neoplasms; Tocotrienols; Vitamin E | 2010 |
Tocotrienols: the lesser known form of natural vitamin E.
Topics: Animals; Biological Availability; Biological Transport; Clinical Trials as Topic; Humans; Neuroprotective Agents; Tocotrienols; Vitamin E | 2011 |
Tocotrienol research: past into present.
Topics: Animals; Antioxidants; Diet; Evidence-Based Medicine; Heart Diseases; Humans; Neoplasms; Tocotrienols; Vitamin E | 2012 |
A history of vitamin E.
Topics: alpha-Tocopherol; Animals; Antioxidants; Carrier Proteins; History, 20th Century; Humans; Tocotrienols; Vitamin E Deficiency | 2012 |
Tocotrienols target PI3K/Akt signaling in anti-breast cancer therapy.
Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Female; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Tocotrienols; Vitamin E | 2013 |
Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures.
Topics: Acute Radiation Syndrome; Animals; Critical Care; Humans; Radiation Protection; Radiation-Protective Agents; Tocopherols; Tocotrienols; Treatment Outcome; Vitamin E | 2013 |
Vitamin E: a dark horse at the crossroad of cancer management.
Topics: Animals; Antioxidants; Dietary Supplements; Drug Screening Assays, Antitumor; Humans; Neoplasms; Tocotrienols; Vitamin E | 2013 |
Vitamin E - Occurrence, Biosynthesis by Plants and Functions in Human Nutrition.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Humans; Immune System; Neurodegenerative Diseases; Plants; Tocopherols; Tocotrienols; Vitamin E | 2017 |
Chromatographic Separation of Vitamin E Enantiomers.
Topics: Chromatography; Chromatography, Gas; Chromatography, High Pressure Liquid; Molecular Structure; Stereoisomerism; Tocopherols; Tocotrienols; Vitamin E | 2017 |
Advances in Genetic Improvement for Tocotrienol Production: A Review.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Biological Availability; Genetic Engineering; Health Promotion; Humans; Palm Oil; Plants; Promoter Regions, Genetic; Tocopherols; Tocotrienols; Vitamin E | 2017 |
Vitamin E and its anticancer effects.
Topics: alpha-Tocopherol; Antineoplastic Agents; Clinical Trials as Topic; gamma-Tocopherol; Humans; Neoplasms; Tocotrienols; Vitamin E | 2019 |
Natural forms of vitamin E and metabolites-regulation of cancer cell death and underlying mechanisms.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cellular Senescence; Cholesterol; Endoplasmic Reticulum Stress; Humans; Molecular Targeted Therapy; Neoplasms; Phosphatidylinositol 3-Kinases; Signal Transduction; Sphingolipids; Tocotrienols; Vitamin E | 2019 |
Utilization of Vitamin E Analogs to Protect Normal Tissues While Enhancing Antitumor Effects.
Topics: Animals; Humans; Neoplasms; Radiation-Protective Agents; Tocotrienols; Vitamin E | 2019 |
Vitamin E and cancer: an update on the emerging role of γ and δ tocotrienols.
Topics: Animals; Humans; Neoplasms; Tocotrienols; Vitamin E | 2020 |
Tocopherols, tocotrienols and tocomonoenols: Many similar molecules but only one vitamin E.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Ataxia; Calcitriol; Dietary Supplements; Humans; Rickets; Scurvy; Stereoisomerism; Terminology as Topic; Tocotrienols; Vitamin E; Vitamin E Deficiency | 2019 |
Vitamin E in Plants: Biosynthesis, Transport, and Function.
Topics: Antioxidants; Chloroplasts; Tocopherols; Tocotrienols; Vitamin E | 2019 |
Antioxidant, Anti-Inflammatory, and Metabolic Properties of Tocopherols and Tocotrienols: Clinical Implications for Vitamin E Supplementation in Diabetic Kidney Disease.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Diabetic Nephropathies; Dietary Supplements; Humans; Oxidative Stress; Tocopherols; Tocotrienols; Vitamin E | 2019 |
Novel Antioxidative Activity of Astaxanthin and Its Synergistic Effect with Vitamin E.
Topics: Antioxidants; Drug Synergism; Liposomes; Superoxides; Tocotrienols; Vitamin E; Xanthophylls | 2019 |
Update on the Anti-Cancer Potency of Tocotrienols and α-Tocopheryl Polyethylene Glycol 1000 Succinate on Leukemic Cell Lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Humans; Polyethylene Glycols; Succinates; Tocotrienols; Vitamin E | 2021 |
Effect of vitamin E on periodontitis: Evidence and proposed mechanisms of action.
Topics: Antioxidants; Dietary Supplements; Humans; Periodontitis; Tocotrienols; Vitamin E | 2021 |
Tocopherols and Tocotrienols-Bioactive Dietary Compounds; What Is Certain, What Is Doubt?
Topics: alpha-Tocopherol; Antioxidants; Diet; gamma-Tocopherol; Humans; Tocotrienols | 2021 |
Reflections on a century of vitamin E research: Looking at the past with an eye on the future.
Topics: Antioxidants; Humans; Tocopherols; Tocotrienols; Vitamin E; Vitamin E Deficiency | 2021 |
Vitamin E as an essential micronutrient for human health: Common, novel, and unexplored dietary sources.
Topics: Antioxidants; Diet; Humans; Micronutrients; Tocopherols; Tocotrienols; Vitamin E | 2021 |
Clinically Relevant Genes and Proteins Modulated by Tocotrienols in Human Colon Cancer Cell Lines: Systematic Scoping Review.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Colonic Neoplasms; Databases, Factual; Gene Expression Regulation, Neoplastic; Humans; Proteins; Tocotrienols; Vitamin E | 2021 |
Interventional study with vitamin E in cardiovascular disease and meta-analysis.
Topics: Antioxidants; Cardiovascular Diseases; Humans; Tocopherols; Tocotrienols; Vitamin E | 2022 |
The Vitamin E Isoform α-Tocopherol is Not Effective as a Complementary Treatment in Cancer Treatment: A Systematic Review.
Topics: alpha-Tocopherol; Antioxidants; Humans; Mucositis; Neoplasms; Protein Isoforms; Tocotrienols; Vitamin E | 2022 |
Vitamin E in foodstuff: Nutritional, analytical, and food technology aspects.
Topics: Animals; Antioxidants; Food Technology; Tocopherols; Tocotrienols; Vitamin E | 2022 |
Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies.
Topics: Anti-Inflammatory Agents; Cardiovascular Diseases; Chronic Disease; Humans; Inflammation; Palm Oil; Tocotrienols; Vitamin E | 2022 |
Revisiting the therapeutic potential of tocotrienol.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Dietary Supplements; Humans; Neoplasms; Tocotrienols; Vitamin E | 2022 |
Free and Esterified Tocopherols, Tocotrienols and Other Extractable and Non-Extractable Tocochromanol-Related Molecules: Compendium of Knowledge, Future Perspectives and Recommendations for Chromatographic Techniques, Tools, and Approaches Used for Tococh
Topics: alpha-Tocopherol; Antioxidants; Tocopherols; Tocotrienols; Vitamin E | 2022 |
Chemopreventive and anti-tumor potential of vitamin E in preclinical breast cancer studies: A systematic review.
Topics: Animals; Antioxidants; Neoplasms; Tocopherols; Tocotrienols; Vitamin E; Vitamins | 2023 |
Tocotrienol in the Management of Nonalcoholic Fatty Liver Disease: A Systematic Review.
Topics: alpha-Tocopherol; Animals; Humans; Liver; Non-alcoholic Fatty Liver Disease; Tocotrienols; Vitamin E | 2023 |
Vitamin E discussion forum position paper on the revision of the nomenclature of vitamin E.
Topics: Antioxidants; Humans; Tocopherols; Tocotrienols; Vitamin E; Vitamins | 2023 |
16 trial(s) available for d-alpha tocopherol and tocotrienols
| Article | Year |
|---|---|
Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status.
Topics: Administration, Oral; Adult; Antioxidants; Area Under Curve; Biological Availability; Chromans; Eating; Fasting; Half-Life; Humans; Male; Middle Aged; Tocotrienols; Vitamin E | 2001 |
Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine.
Topics: Chromans; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Humans; Kinetics; Male; Propionates; Tocotrienols; Vitamin E | 2001 |
Supplementation with 3 compositionally different tocotrienol supplements does not improve cardiovascular disease risk factors in men and women with hypercholesterolemia.
Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Chromans; Dietary Supplements; Dinoprost; Double-Blind Method; F2-Isoprostanes; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Risk Factors; Tocopherols; Tocotrienols; Vitamin E | 2002 |
Topical alpha-tocotrienol supplementation inhibits lipid peroxidation but fails to mitigate increased transepidermal water loss after benzoyl peroxide treatment of human skin.
Topics: Administration, Topical; Adult; Benzoyl Peroxide; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Lipid Peroxidation; Male; Skin; Tocotrienols; Vitamin E; Water Loss, Insensible | 2003 |
Plasma C-reactive protein concentrations in active and passive smokers: influence of antioxidant supplementation.
Topics: alpha-Tocopherol; Antioxidants; Arteriosclerosis; Ascorbic Acid; Body Mass Index; C-Reactive Protein; Dietary Supplements; Double-Blind Method; Female; gamma-Tocopherol; Humans; Male; Middle Aged; Placebos; Smoking; Thioctic Acid; Tobacco Smoke Pollution; Tocotrienols; Vitamins | 2004 |
Dose dependent elevation of plasma tocotrienol levels and its effect on arterial compliance, plasma total antioxidant status, and lipid profile in healthy humans supplemented with tocotrienol rich vitamin E.
Topics: Adult; Antioxidants; Blood Flow Velocity; Blood Pressure; Cholesterol; Compliance; Dietary Supplements; Dose-Response Relationship, Drug; Femoral Artery; Humans; Lipids; Lipoproteins, LDL; Male; Reference Values; Tocotrienols; Vitamin E | 2006 |
Daily supplementation of tocotrienol-rich fraction or alpha-tocopherol did not induce immunomodulatory changes in healthy human volunteers.
Topics: Adult; alpha-Tocopherol; Analysis of Variance; Concanavalin A; Dietary Supplements; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunologic Factors; Immunophenotyping; Interferon-gamma; Interleukin-4; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Mitogens; Palm Oil; Plant Oils; Tocotrienols; Treatment Failure; Vitamin E; Young Adult | 2009 |
Arterial compliance and vitamin E blood levels with a self emulsifying preparation of tocotrienol rich vitamin E.
Topics: Adult; Antioxidants; Biological Availability; Blood Pressure; Blood Vessels; Cholesterol; Cholesterol, LDL; Double-Blind Method; Emulsions; Endpoint Determination; Humans; Male; Tocotrienols; Vascular Resistance; Vitamin E | 2008 |
Plasma vitamin C and tocotrienols changes in response to dietary supplementation among young male adults.
Topics: Adult; Ascorbic Acid; Chromans; Dietary Supplements; Humans; Male; Tocotrienols; Vitamin E; Vitamins; Young Adult | 2010 |
Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients.
Topics: Adult; Biological Transport, Active; Dietary Supplements; Disease Progression; End Stage Liver Disease; Female; Humans; Liver Transplantation; Male; Prospective Studies; Tissue Distribution; Tocopherols; Tocotrienols; Vitamin E | 2012 |
Tocotrienols for normalisation of hepatic echogenic response in nonalcoholic fatty liver: a randomised placebo-controlled clinical trial.
Topics: Adult; Aged; Alanine Transaminase; alpha-Tocopherol; Apolipoproteins B; Aspartate Aminotransferases; C-Reactive Protein; Cholesterol; Dose-Response Relationship, Drug; Double-Blind Method; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Nutrition Assessment; Prospective Studies; Risk Factors; Tocotrienols; Triglycerides; Ultrasonography | 2013 |
A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects.
Topics: Adult; Analysis of Variance; Area Under Curve; Biological Availability; Chromans; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Compounding; Female; Half-Life; Healthy Volunteers; Humans; Isomerism; Male; ROC Curve; Tocotrienols; Vitamin E; Young Adult | 2015 |
Acute effects of a single dose of tocotrienols on insulinemic and inflammatory responses in metabolic syndrome subjects after a high-fat challenge.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents; Blood Glucose; C-Peptide; Cross-Over Studies; Diet, High-Fat; Dietary Supplements; Double-Blind Method; Fatty Acids, Nonesterified; Female; Fibrinolytic Agents; Humans; Insulin; Male; Metabolic Syndrome; Middle Aged; Postprandial Period; Tocotrienols; Triglycerides; Vitamin E; Vitamins; Young Adult | 2017 |
Comparing palm oil tocotrienol rich fraction with α-tocopherol supplementation on oxidative stress in healthy older adults.
Topics: alpha-Tocopherol; Chromans; Comet Assay; Dietary Supplements; DNA Damage; Female; Humans; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Palm Oil; Protein Carbonylation; Reactive Oxygen Species; Tocotrienols; Vitamin D; Vitamin E | 2017 |
Comparing the effects of vitamin E tocotrienol-rich fraction supplementation and α-tocopherol supplementation on gene expression in healthy older adults.
Topics: alpha-Tocopherol; Antioxidants; Cell Adhesion; Dietary Supplements; Female; Gene Expression; Gene Expression Regulation; Humans; Immune System; Male; Middle Aged; Oxidative Stress; Protein Kinases; Sex Factors; Signal Transduction; Single-Blind Method; Time Factors; Tocotrienols | 2019 |
Tocotrienol-Rich Vitamin E (Tocovid) Improved Nerve Conduction Velocity in Type 2 Diabetes Mellitus Patients in a Phase II Double-Blind, Randomized Controlled Clinical Trial.
Topics: Aged; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Median Nerve; Middle Aged; Motor Neurons; Neural Conduction; Sural Nerve; Tibia; Tocotrienols; Transforming Growth Factor beta1; Treatment Outcome; Vascular Endothelial Growth Factor A; Vitamin E | 2021 |
222 other study(ies) available for d-alpha tocopherol and tocotrienols
| Article | Year |
|---|---|
Hypocholesterolemic activity of synthetic and natural tocotrienols.
Topics: Animals; Anticholesteremic Agents; Cells, Cultured; Chickens; Cholesterol; Chromans; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Rats; Rats, Wistar; Tocotrienols; Vitamin E | 1992 |
Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol.
Topics: Animals; Antioxidants; Chromans; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Lipid Bilayers; Lipid Peroxidation; Liposomes; Magnetic Resonance Spectroscopy; Membrane Fluidity; Membrane Lipids; Microsomes, Liver; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Tocotrienols; Vitamin E | 1991 |
The tocopherol, tocotrienol, and vitamin E content of the average Finnish diet.
Topics: Antioxidants; Chromans; Diet; Eating; Fatty Acids, Unsaturated; Finland; Food Analysis; Humans; Seasons; Tocotrienols; Vitamin E | 1991 |
Functions of vitamin E in reproduction and in prostacyclin and immunoglobulin synthesis in rats.
Topics: Animals; Epoprostenol; Female; Immunoglobulin G; Palm Oil; Plant Oils; Pregnancy; Pregnancy, Animal; Pyruvate Kinase; Rats; Tocotrienols; Vitamin E | 1991 |
Studies on the biological activity of tocotrienols.
Topics: Animals; Antineoplastic Agents; Chromans; Female; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Tocotrienols; Vitamin E | 1989 |
High-performance liquid chromatographic determination of tocopherols and tocotrienols and its application to diets and plasma of Finnish men. I. Analytical method.
Topics: Butylated Hydroxyanisole; Chromans; Chromatography, High Pressure Liquid; Food, Formulated; Hexanes; Humans; Hydroxides; Male; Potassium; Potassium Compounds; Solvents; Tocotrienols; Vitamin E | 1984 |
Carotenoids, retinoids, tocopherols and tocotrienols in the diet; the Finnish Mobile Clinic Health Examination Survey.
Topics: Adult; Antioxidants; Carotenoids; Chromatography, High Pressure Liquid; Diet; Female; Finland; Food Analysis; Health Surveys; Humans; Male; Middle Aged; Mobile Health Units; Nutrition Surveys; Retinoids; Tocotrienols; Vitamin E | 1995 |
Antioxidative activity of tocotrienol in heterogeneous system: indication of restriction within membrane by fluorescence measurement.
Topics: Antioxidants; Diphenylhexatriene; Dose-Response Relationship, Drug; Liposomes; Phospholipids; Spectrometry, Fluorescence; Structure-Activity Relationship; Tocotrienols; Vitamin E | 1994 |
Antioxidant properties of alpha-tocopherol and alpha-tocotrienol.
Topics: Animals; Antioxidants; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Free Radical Scavengers; Free Radicals; Hexanes; Humans; Indicators and Reagents; Iron; Kinetics; Lipid Peroxidation; Liposomes; Microsomes; Mitochondria, Heart; Myocardium; Rats; Superoxides; Tocotrienols; Vitamin E | 1994 |
Vitamin E, glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured hepatocytes of rats treated with carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cells, Cultured; Diethylnitrosamine; Drug Interactions; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Male; Rats; Thymidine; Tocotrienols; Vitamin E | 1994 |
Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: implication to the molecular mechanism of their antioxidant potency.
Topics: Antioxidants; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Membranes; Models, Biological; Oxygen Consumption; Peroxides; Spectrometry, Fluorescence; Thermodynamics; Tocotrienols; Vitamin E | 1993 |
Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins.
Topics: Adult; Animals; Antioxidants; Chromans; Dietary Fats, Unsaturated; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Oxidation-Reduction; Palm Oil; Plant Oils; Rats; Tocotrienols; Vitamin E | 1993 |
Tocotrienol and fatty acid composition of barley oil and their effects on lipid metabolism.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Cholesterol, HDL; Cholesterol, LDL; Chromans; Corn Oil; Diet; Dietary Fats, Unsaturated; Fatty Acids; Hordeum; Lipid Metabolism; Male; Margarine; Plant Oils; Tocotrienols; Triglycerides; Vitamin E; Weight Gain | 1993 |
Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria.
Topics: Animals; Antioxidants; Brain; Dietary Fats, Unsaturated; Female; Lipid Peroxidation; Mitochondria; Oxidation-Reduction; Palm Oil; Plant Oils; Proteins; Rats; Rats, Wistar; Tocotrienols; Vitamin E | 1995 |
Lymphatic transport of alpha-, gamma- and delta-tocotrienols and alpha-tocopherol in rats.
Topics: Animals; Biological Transport; Chromans; Emulsions; Intestinal Absorption; Kinetics; Lymphatic System; Male; Oleic Acid; Rats; Rats, Sprague-Dawley; Thoracic Duct; Tocotrienols; Triolein; Vitamin E | 1996 |
Nitrofurantoin-induced hepatic and pulmonary biochemical changes in mice fed different vitamin E doses.
Topics: Animals; Antioxidants; Catalase; Drug Interactions; Glutathione; Glutathione Peroxidase; Liver; Lung; Male; Malondialdehyde; Mice; Nitrofurantoin; Tocotrienols; Vitamin E; Vitamin E Deficiency | 1996 |
Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination.
Topics: Antineoplastic Agents, Hormonal; Antioxidants; Breast Neoplasms; Cell Division; Cell Survival; Chromans; Dietary Fats, Unsaturated; Drug Interactions; Estrogen Antagonists; Female; Humans; Palm Oil; Plant Oils; Receptors, Estrogen; Tamoxifen; Tocotrienols; Tumor Cells, Cultured; Vitamin E | 1997 |
Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes.
Topics: Animals; Antioxidants; Chromans; Female; Kinetics; Lipid Peroxidation; Microsomes, Liver; Oxidation-Reduction; Palm Oil; Plant Oils; Proteins; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tocotrienols; Vitamin E | 1997 |
Penetration and distribution of alpha-tocopherol, alpha- or gamma-tocotrienols applied individually onto murine skin.
Topics: Administration, Topical; Animals; Chromans; Female; Kinetics; Mice; Mice, Hairless; Polyethylene Glycols; Skin; Solutions; Tissue Distribution; Tocotrienols; Vitamin E | 1998 |
Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status.
Topics: Breast Neoplasms; Cell Division; Estradiol; Female; Humans; Insulin-Like Growth Factor Binding Proteins; Receptors, Estrogen; Tocotrienols; Tumor Cells, Cultured; Vitamin E | 1998 |
Selective excretion of yolk-derived tocotrienols into the bile of the chick embryo.
Topics: Animals; Animals, Newborn; Bile; Chick Embryo; Chickens; Chromans; Liver; Tissue Distribution; Tocotrienols; Vitamin E; Yolk Sac | 1998 |
Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols.
Topics: Antioxidants; Apoptosis; Breast Neoplasms; Chromans; Chromatin; DNA, Neoplasm; Female; Humans; Neoplasms, Hormone-Dependent; Tocotrienols; Tumor Cells, Cultured; Vitamin E | 1999 |
Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue.
Topics: Animals; Antioxidants; Cattle; Cholesterol; Chromans; Chromatography, High Pressure Liquid; Muscles; Saponins; Sensitivity and Specificity; Tocotrienols; Vitamin E | 1999 |
Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells.
Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Chromans; DNA Fragmentation; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Female; Inhibitory Concentration 50; Isomerism; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Palm Oil; Plant Oils; Tocotrienols; Vitamin E | 2000 |
Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells.
Topics: Animals; Benzoquinones; Cell Death; Cells, Cultured; Chelating Agents; Chromans; Chromatography, High Pressure Liquid; Deferoxamine; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Glutamic Acid; Hippocampus; Immunoblotting; Lactams, Macrocyclic; Mice; Neurons; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Signal Transduction; Time Factors; Tocotrienols; Transfection; Vitamin E | 2000 |
Effects of tocotrienols on life span and protein carbonylation in Caenorhabditis elegans.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Chromans; Longevity; Proteins; Tocotrienols; Vitamin E | 2000 |
Selective uptake of dietary tocotrienols into rat skin.
Topics: Animals; Antioxidants; Chromans; Diet; Female; Kidney; Liver; Male; Mice; Mice, Hairless; Mice, Inbred BALB C; Mice, Nude; Rats; Rats, Wistar; Skin; Tissue Distribution; Tocotrienols; Vitamin E | 2000 |
Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Chromans; Chromatography, High Pressure Liquid; Dietary Fats; Female; Lipid Metabolism; Lipoproteins; Liver; Male; Mice; Mice, Inbred C57BL; Tocotrienols; Triglycerides; Vitamin E | 2000 |
Oxidative damage to mitochondria in normal and cancer tissues, and its modulation.
Topics: Animals; Antioxidants; Ascites; Brain; Caffeine; Gamma Rays; Male; Mitochondria, Liver; Niacinamide; Oxidative Stress; Palm Oil; Photosensitizing Agents; Plant Oils; Porphyrins; Pulse Radiolysis; Rats; Rats, Wistar; Sarcoma 180; Tocotrienols; Vitamin E | 2000 |
Removal of fat from cow's milk decreases the vitamin E contents of the resulting dairy products.
Topics: Animals; Cholesterol; Dairy Products; Food Handling; Lipids; Milk; Tocotrienols; Vitamin E | 2001 |
Determination of RS,E/Z-tocotrienols by HPLC.
Topics: Chromatography, High Pressure Liquid; Sensitivity and Specificity; Stereoisomerism; Tocotrienols; Vitamin E | 2001 |
Oral toxicity of a tocotrienol preparation in rats.
Topics: Administration, Oral; Adrenal Glands; Animals; Blood Cell Count; Chromans; Dose-Response Relationship, Drug; Female; Food Additives; Genitalia; Kidney; Liver; Male; No-Observed-Adverse-Effect Level; Rats; Rats, Inbred F344; Sex Factors; Tocotrienols; Vitamin E | 2001 |
Relationship between fatty acid profile and vitamin E content in maize hybrids (Zea mays L.).
Topics: Fatty Acids; Hybridization, Genetic; Linoleic Acid; Oleic Acid; Palmitic Acid; Tocopherols; Tocotrienols; Vitamin E; Zea mays | 2001 |
Dietary sesame seeds elevate alpha- and gamma-tocotrienol concentrations in skin and adipose tissue of rats fed the tocotrienol-rich fraction extracted from palm oil.
Topics: Adipose Tissue; Analysis of Variance; Animals; Body Weight; Chromans; Diet; Male; Organ Size; Palm Oil; Plant Oils; Rats; Rats, Wistar; Seeds; Skin; Tissue Distribution; Tocotrienols; Vitamin E | 2001 |
Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation.
Topics: alpha-Tocopherol; Animals; Blotting, Western; Cell Division; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Female; gamma-Tocopherol; Mice; Mice, Inbred BALB C; Pregnancy; Protein Kinase C; Time Factors; Tocotrienols; Vitamin E | 2001 |
Tocotrienol is the most effective vitamin E for reducing endothelial expression of adhesion molecules and adhesion to monocytes.
Topics: Antioxidants; Cell Survival; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; NF-kappa B; Protein Prenylation; Tetradecanoylphorbol Acetate; Tocotrienols; Tumor Necrosis Factor-alpha; Vitamin E | 2002 |
Effect of either gamma-tocotrienol or a tocotrienol mixture on the plasma lipid profile in hamsters.
Topics: Acyl Coenzyme A; Animals; Anticholesteremic Agents; Antioxidants; Cholesterol; Chromans; Cricetinae; Lipids; Lipoproteins, LDL; Male; Mesocricetus; Random Allocation; Simvastatin; Tocotrienols; Vitamin E | 2002 |
Protective effect of alpha-tocotrienol against free radical-induced impairment of erythrocyte deformability.
Topics: Erythrocyte Deformability; Free Radicals; Hemolysis; Humans; Lipid Peroxidation; Oxidation-Reduction; Tocotrienols; Vitamin E | 2002 |
Analysis of tocotrienols in different sample matrixes by HPLC.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Fats; Food Analysis; Guinea Pigs; Liver; Tocotrienols; Vitamin E | 2002 |
Effect of sesaminol on plasma and tissue alpha-tocopherol and alpha-tocotrienol concentrations in rats fed a vitamin E concentrate rich in tocotrienols.
Topics: alpha-Tocopherol; Animals; Dioxoles; Furans; Male; Rats; Rats, Wistar; Tissue Distribution; Tocotrienols; Vitamin E | 2002 |
Simultaneous detection of tocopherols and tocotrienols in biological samples using HPLC-coulometric electrode array.
Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Rats; Spectrophotometry; Time Factors; Tocopherols; Tocotrienols; Vitamin E | 2002 |
Vitamin E isoforms alpha-tocotrienol and gamma-tocopherol prevent cerebral infarction in mice.
Topics: Animals; gamma-Tocopherol; Infarction, Middle Cerebral Artery; Male; Mice; Structure-Activity Relationship; Tocotrienols; Vitamin E | 2003 |
HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity.
Topics: alpha-Tocopherol; Chromans; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Epidermis; Erythema; Free Radical Scavengers; Free Radicals; gamma-Tocopherol; Humans; Isomerism; Microbial Sensitivity Tests; Tocotrienols; Vitamin E | 2003 |
Dietary alpha-tocopherol decreases alpha-tocotrienol but not gamma-tocotrienol concentration in rats.
Topics: Adipose Tissue; alpha-Tocopherol; Animals; Antioxidants; Body Weight; Chromans; Diet; Male; Pyruvate Kinase; Rats; Rats, Wistar; Tissue Distribution; Tocotrienols; Vitamin E | 2003 |
Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats.
Topics: Administration, Oral; Animals; Biological Availability; Chromans; Cross-Over Studies; Infusions, Intravenous; Infusions, Parenteral; Injections, Intramuscular; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tocotrienols; Vitamin E | 2003 |
Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion.
Topics: Arteriosclerosis; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Models, Biological; Monocytes; Tocotrienols; Umbilical Veins; Vitamin E | 2002 |
Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia.
Topics: Base Sequence; Carrier Proteins; Cell Line; DNA Primers; Dysautonomia, Familial; Exons; Gene Expression; Humans; Kinetics; Mutation; RNA Splicing; RNA, Messenger; Tissue Distribution; Tocotrienols; Transcription, Genetic; Transcriptional Elongation Factors; Vitamin E | 2003 |
Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants.
Topics: alpha-Tocopherol; Antioxidants; Cell Adhesion; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Humans; Lipid Peroxidation; Monocytes; Tocotrienols; Vascular Cell Adhesion Molecule-1; Vitamin E | 2003 |
Metabolic redesign of vitamin E biosynthesis in plants for tocotrienol production and increased antioxidant content.
Topics: Alkyl and Aryl Transferases; Antioxidants; Arabidopsis; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Engineering; Hordeum; Multienzyme Complexes; Oryza; Plant Leaves; Plants, Genetically Modified; Protein Engineering; Recombinant Proteins; Tocopherols; Tocotrienols; Triticum; Vitamin E | 2003 |
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration.
Topics: Animals; Arachidonate 12-Lipoxygenase; Binding Sites; Cell Death; Cell Survival; Cells, Cultured; Cytosol; Glutamic Acid; Glutathione; Hippocampus; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Models, Molecular; Neurodegenerative Diseases; Neurons; Neurotoxins; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Time Factors; Tocotrienols; Vitamin E | 2003 |
Corn with enhanced antioxidant potential.
Topics: Alkyl and Aryl Transferases; Antioxidants; Arabidopsis; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Engineering; Hordeum; Multienzyme Complexes; Oryza; Plant Leaves; Plants, Genetically Modified; Protein Engineering; Recombinant Proteins; Tocopherols; Tocotrienols; Triticum; Vitamin E; Zea mays | 2003 |
Antioxidant activities of natural vitamin E formulations.
Topics: Amidines; Antioxidants; Chromans; Cyclodextrins; Fluorescein; Free Radicals; Humans; Indicators and Reagents; Oxygen Compounds; Peroxides; Tocopherols; Tocotrienols; Vitamin E | 2003 |
Engineering plant shikimate pathway for production of tocotrienol and improving herbicide resistance.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Arabidopsis; Base Sequence; DNA, Recombinant; Drug Resistance; Enzyme Inhibitors; Escherichia coli; Genes, Fungal; Genes, Plant; Genetic Engineering; Herbicides; Nicotiana; Plant Leaves; Plants, Genetically Modified; Prephenate Dehydrogenase; Saccharomyces cerevisiae; Shikimic Acid; Tocotrienols; Vitamin E | 2004 |
Effects of tocopherols and tocotrienols on body composition and bone calcium content in adrenalectomized rats replaced with dexamethasone.
Topics: Adrenalectomy; alpha-Tocopherol; Animals; Antioxidants; Body Composition; Bone and Bones; Bone Density; Calcium; Dexamethasone; Male; Obesity; Osteoporosis; Palm Oil; Plant Oils; Random Allocation; Rats; Rats, Sprague-Dawley; Tocopherols; Tocotrienols | 2004 |
Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations.
Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Chromans; Chromatography, High Pressure Liquid; Cross-Over Studies; Emulsions; Glycerides; Half-Life; Humans; Lipolysis; Male; Organic Chemicals; Particle Size; Polysorbates; Soybean Oil; Tocotrienols; Vitamin E | 2004 |
To "E" or not to "E," vitamin E's role in health and disease is the question.
Topics: alpha-Tocopherol; Animals; Antioxidants; Breast Neoplasms; Cardiovascular Diseases; Colonic Neoplasms; gamma-Tocopherol; Humans; Oxidative Stress; Tocotrienols; Vitamin E | 2004 |
Distribution of tocopherols and tocotrienols to rat ocular tissues after topical ophthalmic administration.
Topics: Administration, Topical; Animals; Eye; Male; Rats; Rats, Wistar; Tissue Distribution; Tocopherols; Tocotrienols; Vitamin E | 2004 |
Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons.
Topics: Animals; Antimetabolites; Antioxidants; Apoptosis; Bisbenzimidazole; Buthionine Sulfoximine; Carcinogens; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Fluorescent Dyes; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neostriatum; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Staurosporine; Tetrazolium Salts; Thiazoles; Tocotrienols; Vitamin E | 2004 |
Separation of vitamin E (tocopherol, tocotrienol, and tocomonoenol) in palm oil.
Topics: Chromatography, High Pressure Liquid; Esterification; Palm Oil; Plant Oils; Tocopherols; Tocotrienols; Vitamin E | 2004 |
Characterization of cellular uptake and distribution of vitamin E.
Topics: alpha-Tocopherol; Antioxidants; Cell Fractionation; Cell Survival; Humans; Jurkat Cells; Oxidative Stress; Subcellular Fractions; Tocotrienols; Vitamin E | 2004 |
Vitamin E exhibits concentration- and vitamer-dependent impairment of microsomal enzyme activities.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Microsomes, Liver; Mixed Function Oxygenases; Rats; Tocopherols; Tocotrienols; Vitamin E | 2004 |
Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expression of adhesion molecules.
Topics: alpha-Tocopherol; Antibodies, Monoclonal; Antioxidants; Aorta; Cell Adhesion; Cell Communication; Endothelium, Vascular; Gene Expression; Humans; Hydroxycholesterols; Monocytes; RNA, Messenger; Tocotrienols; U937 Cells; Vascular Cell Adhesion Molecule-1 | 2005 |
Vitamin E deficiency reduced lumbar bone calcium content in female rats.
Topics: alpha-Tocopherol; Amino Acids; Animals; Antioxidants; Calcium; Creatinine; Dietary Supplements; Female; Lumbar Vertebrae; Osteocalcin; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Tocotrienols; Vitamin E; Vitamin E Deficiency | 2004 |
Tocotrienol inhibits proliferation of human Tenon's fibroblasts in vitro: a comparative study with vitamin E forms and mitomycin C.
Topics: Aged; Aged, 80 and over; Antioxidants; Cell Proliferation; Cells, Cultured; Conjunctiva; Cytoplasm; DNA; Fibroblasts; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; Mitomycin; Nucleic Acid Synthesis Inhibitors; Tocotrienols; Vitamin E | 2005 |
Vitamin E composition of walnuts (Juglans regia L.): a 3-year comparative study of different cultivars.
Topics: Chromatography, High Pressure Liquid; Juglans; Seeds; Species Specificity; Tocopherols; Tocotrienols; Vitamin E | 2005 |
Lipid peroxidation induced by carbon tetrachloride and its inhibition by antioxidant as evaluated by an oxidative stress marker, HODE.
Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Benzofurans; Biomarkers; Carbon Tetrachloride; Carrier Proteins; Chromatography, High Pressure Liquid; Diet; Dinoprost; Fatty Acids, Unsaturated; Genotype; Injections, Intraperitoneal; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Specific Pathogen-Free Organisms; Thiobarbituric Acid Reactive Substances; Tocotrienols; Ubiquinone; Vitamin E | 2005 |
Neuroprotective properties of the natural vitamin E alpha-tocotrienol.
Topics: Animals; Antioxidants; Arachidonate 12-Lipoxygenase; Brain; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Cerebral Cortex; CSK Tyrosine-Protein Kinase; Fluoresceins; Glutamic Acid; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuroprotective Agents; Organic Chemicals; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Random Allocation; Rats; Rats, Inbred SHR; src-Family Kinases; Stroke; Time Factors; Tocotrienols; Transfection; Tyrosine; Vitamin E | 2005 |
Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone.
Topics: alpha-Tocopherol; Amino Acids; Animals; Antioxidants; Bone and Bones; Dose-Response Relationship, Drug; Ferric Compounds; Free Radicals; Interleukin-1; Interleukin-6; Male; Nitrilotriacetic Acid; Osteocalcin; Rats; Rats, Wistar; Tocopherols; Tocotrienols | 2005 |
Delivery of orally supplemented alpha-tocotrienol to vital organs of rats and tocopherol-transport protein deficient mice.
Topics: Administration, Oral; Animals; Antioxidants; Biological Transport; Carrier Proteins; Female; Humans; Lung; Male; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Tocopherols; Tocotrienols; Vitamin E | 2005 |
Effect of temperature, cholesterol content, and antioxidant structure on the mobility of vitamin E constituents in biomembrane models studied by laterally diffusion-controlled fluorescence quenching.
Topics: Antioxidants; Cholesterol; Diffusion; Fluorescence; Liposomes; Phosphatidylcholines; Temperature; Tocopherols; Tocotrienols; Vitamin E | 2005 |
Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line, Tumor; Chromans; Gene Expression; Genes, bcl-2; Humans; Liver Neoplasms; Poly(ADP-ribose) Polymerases; Tocotrienols; Vitamin E | 2006 |
Chemoenzymatic synthesis of both enantiomers of alpha-tocotrienol.
Topics: Acylation; Candida; Esters; Fungal Proteins; Hydrolysis; Lipase; Molecular Structure; Stereoisomerism; Tocotrienols; Vitamin E | 2006 |
Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase.
Topics: alpha-Tocopherol; Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Cytoprotection; Enzyme Inhibitors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Tocotrienols; Up-Regulation; Vitamin E | 2006 |
Characterization of the potent neuroprotective properties of the natural vitamin E alpha-tocotrienol.
Topics: Animals; Arachidonate 12-Lipoxygenase; Calcium; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Glutathione; Hippocampus; Homocysteine; Hydro-Lyases; Linoleic Acid; Membrane Potentials; Mice; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Time Factors; Tocotrienols; Vitamin E | 2006 |
Dose-response impact of various tocotrienols on serum lipid parameters in 5-week-old female chickens.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Chickens; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Hypercholesterolemia; Lipid Metabolism; Lipids; Palm Oil; Plant Oils; Tocotrienols; Vitamin E | 2006 |
Natural vitamin E alpha-tocotrienol: retention in vital organs in response to long-term oral supplementation and withdrawal.
Topics: Adipose Tissue; Administration, Oral; alpha-Tocopherol; Animals; Biological Availability; Central Nervous System; Dietary Supplements; Female; Gonads; Liver; Lung; Male; Muscle, Skeletal; Myocardium; Neuroprotective Agents; Rats; Skin; Tissue Distribution; Tocotrienols | 2006 |
Postprandial metabolic fate of tocotrienol-rich vitamin E differs significantly from that of alpha-tocopherol.
Topics: Adult; alpha-Tocopherol; Antioxidants; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Lipoproteins; Male; Postprandial Period; Reference Values; Time Factors; Tocotrienols; Triglycerides; Vitamin E | 2006 |
Triton WR1339, an inhibitor of lipoprotein lipase, decreases vitamin E concentration in some tissues of rats by inhibiting its transport to liver.
Topics: alpha-Tocopherol; Animals; Biological Transport; Chromans; gamma-Tocopherol; Lipoprotein Lipase; Liver; Male; Polyethylene Glycols; Rats; Rats, Wistar; Tocotrienols; Triglycerides; Vitamin E | 2007 |
Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase.
Topics: Cell Line, Tumor; Humans; Kinetics; Microsomes; Mixed Function Oxygenases; Molecular Structure; Oxidation-Reduction; Substrate Specificity; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Distribution of tocotrienols in rats fed a rice bran tocotrienol concentrate.
Topics: Animals; Antioxidants; Body Weight; Chromans; Chromatography, High Pressure Liquid; Diet; Lipid Peroxidation; Male; Oryza; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Tissue Distribution; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Effects of new combinative antioxidant FeAOX-6 and alpha-tocotrienol on macrophage atherogenesis-related functions.
Topics: Antioxidants; Arachidonic Acid; Atherosclerosis; Cells, Cultured; Cholesterol; Cholesterol Esters; Chromans; Cytokines; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Foam Cells; Free Radicals; Humans; Inflammation; Macrophages; Receptors, Scavenger; Tocotrienols; Vitamin E | 2007 |
Effects of vitamin E supplementation on bone metabolism in nicotine-treated rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Bone and Bones; Calcium; Dietary Supplements; Interleukin-1; Interleukin-6; Lumbar Vertebrae; Male; Nicotine; Osteocalcin; Rats; Rats, Sprague-Dawley; Tocotrienols; Vitamin E | 2007 |
Comparative study of the effect of tocotrienols and -tocopherol on fasting serum lipid profiles in patients with mild hypercholesterolaemia: a preliminary report.
Topics: Cardiovascular Diseases; Fasting; Humans; Hypercholesterolemia; Lipids; Nigeria; Risk Factors; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Comprehensive analysis of vitamin E constituents in human plasma by liquid chromatography-mass spectrometry.
Topics: Animals; Chromatography, Liquid; Fish Oils; Humans; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Tocotrienol levels in adipose tissue of benign and malignant breast lumps in patients in Malaysia.
Topics: Adipose Tissue; Antioxidants; Breast; Breast Diseases; Breast Neoplasms; Dietary Fats, Unsaturated; Female; Humans; Malaysia; Nutritional Status; Palm Oil; Plant Oils; Tocopherols; Tocotrienols; Vitamin E | 2007 |
Modulation of proteasome activity by vitamin E in THP-1 monocytes.
Topics: Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Humans; Intracellular Signaling Peptides and Proteins; Leupeptins; Monocytes; Oxidative Stress; Protease Inhibitors; Proteasome Endopeptidase Complex; Ritonavir; Tocopherols; Tocotrienols; Tumor Suppressor Protein p53; Tyrosine; Vitamin E | 2007 |
Effect of apoE genotype and vitamin E on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Antioxidants; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Biomarkers; Brain; Cell Death; Cell Line, Tumor; Female; gamma-Tocopherol; Genotype; Humans; Lipid Peroxidation; Mice; Mice, Transgenic; Neurons; Nitric Oxide; Oxidative Stress; Tocotrienols; Vitamin E | 2007 |
Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Dioxoles; Drug Synergism; Female; Food, Formulated; Lignans; Liver; Mice; Mice, Hairless; Palm Oil; Papilloma; Plant Oils; Skin; Skin Neoplasms; Sunburn; Thiobarbituric Acid Reactive Substances; Tocotrienols; Ultraviolet Rays; Vitamin E | 2008 |
Palm tocotrienol exerted better antioxidant activities in bone than alpha-tocopherol.
Topics: Administration, Oral; alpha-Tocopherol; Animals; Antioxidants; Bone and Bones; Dietary Supplements; Femur; Glutathione Peroxidase; Lipid Peroxidation; Male; Oxidative Stress; Palm Oil; Plant Oils; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tocotrienols | 2008 |
Inhibition of oxidative metabolism of tocopherols with omega-N-heterocyclic derivatives of vitamin E.
Topics: Animals; Benzimidazoles; Bile; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mixed Function Oxygenases; Tocopherols; Tocotrienols; Triazoles; Vitamin E | 2008 |
Effect of astaxanthin in combination with alpha-tocopherol or ascorbic acid against oxidative damage in diabetic ODS rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Diabetic Nephropathies; Diabetic Neuropathies; Drug Therapy, Combination; Kidney; Liver; Organ Size; Oxidative Stress; Rats; Rats, Inbred Strains; Tocotrienols; Xanthophylls | 2008 |
Tocotrienol and alpha-tocopherol reduce corticosterone and noradrenalin levels in rats exposed to restraint stress.
Topics: alpha-Tocopherol; Animals; Antioxidants; Corticosterone; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Gastric Mucosa; Lipid Peroxidation; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Psychological; Tocotrienols | 2008 |
Optimization of the enzymatic hydrolysis and analysis of plasma conjugated gamma-CEHC and sulfated long-chain carboxychromanols, metabolites of vitamin E.
Topics: Animals; Cell Line; Chromans; Chromatography, High Pressure Liquid; Glucuronidase; Hexanes; Humans; Male; Methanol; Plasma; Rats; Rats, Wistar; Sulfatases; Tocopherols; Tocotrienols; Vitamin E | 2009 |
Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats.
Topics: Acetylcholinesterase; alpha-Tocopherol; Animals; Antioxidants; Brain; Catalase; Cognition Disorders; Dementia; Glutathione; Injections, Intraventricular; Lipid Peroxidation; Male; Maze Learning; Mitochondria; Motor Activity; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Reactive Nitrogen Species; Streptozocin; Superoxide Dismutase; Tocotrienols | 2009 |
Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats.
Topics: Acetylcholinesterase; Alcohol Amnestic Disorder; alpha-Tocopherol; Animals; Cerebral Cortex; Enzyme-Linked Immunosorbent Assay; Hippocampus; Interleukin-1beta; Lipid Peroxidation; Male; Maze Learning; Memory; Motor Activity; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Tocotrienols; Tumor Necrosis Factor-alpha | 2009 |
Vitamin E profile as a reliable authenticity discrimination factor between chestnut (Castanea sativa Mill.) cultivars.
Topics: Fagaceae; Nuts; Plant Oils; Quality Control; Tocotrienols; Vitamin E | 2009 |
Tocotrienols suppress proinflammatory markers and cyclooxygenase-2 expression in RAW264.7 macrophages.
Topics: alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprostone; Gene Expression Regulation; Lipopolysaccharides; Macrophages; Mice; Nitrogen Oxides; Tocotrienols | 2009 |
Effect of tocotrienols on iron-induced renal dysfunction and oxidative stress in rats.
Topics: alpha-Tocopherol; Animals; Anticarcinogenic Agents; Blood Urea Nitrogen; Carcinogens; Creatinine; Ferric Compounds; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Nitrilotriacetic Acid; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Tocotrienols; Vitamin E | 2009 |
Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Death; Cell Line, Transformed; Cell Size; Chelating Agents; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fatty Acids; Glutamic Acid; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phospholipase A2 Inhibitors; Phospholipases A2; RNA, Small Interfering; Subcellular Fractions; Tocotrienols; Transfection; Vitamin E | 2010 |
Involvement of Ca2+ and ROS in alpha-tocopheryl succinate-induced mitochondrial permeabilization.
Topics: alpha-Tocopherol; Animals; Antioxidants; Calcium; Caspase 3; Cell Membrane Permeability; Cells, Cultured; Cytochromes c; Humans; Hydrogen Peroxide; Jurkat Cells; Male; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroblastoma; Oxidants; Permeability; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tocotrienols; Vitamin E | 2010 |
Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Chromans; Humans; Liver X Receptors; Male; Mice; Orphan Nuclear Receptors; Palm Oil; Peroxisome Proliferator-Activated Receptors; Plant Oils; PPAR alpha; Tocotrienols; Tumor Cells, Cultured; Vitamin E | 2010 |
Tocotrienols inhibited growth and induced apoptosis in human HeLa cells through the cell cycle signaling pathway.
Topics: alpha-Tocopherol; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor Proteins; Cytokines; Down-Regulation; Drug Evaluation, Preclinical; HeLa Cells; Humans; Signal Transduction; Tocotrienols | 2010 |
Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chromans; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Mice; Receptor, ErbB-2; Tocotrienols; Vitamin E | 2010 |
Molecular interaction and localization of tocotrienol-rich fraction (TRF) within the matrices of lipid nanoparticles: evidence studies by Differential Scanning Calorimetry (DSC) and Proton Nuclear Magnetic Resonance spectroscopy ((1)H NMR).
Topics: Calorimetry, Differential Scanning; Crystallization; Drug Carriers; Drug Delivery Systems; Emulsions; Lipids; Magnetic Resonance Spectroscopy; Nanoparticles; Nanostructures; Nanotechnology; Particle Size; Software; Surface Properties; Tocotrienols; Vitamin E | 2010 |
In vitro antioxidant activity of tocopherols and tocotrienols and comparison of vitamin E concentration and lipophilic antioxidant capacity in human plasma.
Topics: Antioxidants; Free Radical Scavengers; Humans; Molecular Weight; Reproducibility of Results; Spectrometry, Fluorescence; Tocopherols; Tocotrienols; Vitamin E | 2010 |
Palm oil tocotrienol fractions restore endothelium dependent relaxation in aortic rings of streptozotocin-induced diabetic and spontaneously hypertensive rats.
Topics: Acetylcholine; alpha-Tocopherol; Animals; Antioxidants; Aorta; Biphenyl Compounds; Diabetes Mellitus, Experimental; Endothelium, Vascular; Free Radical Scavengers; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Palm Oil; Picrates; Plant Oils; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tocotrienols; Vasodilation | 2010 |
Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function.
Topics: alpha-Tocopherol; Animals; Antioxidants; Cell Death; Cerebral Cortex; Glutamic Acid; Glutathione; Neurons; Rats; Tocopherols; Tocotrienols; Vitamin E | 2010 |
Common variants of cytochrome P450 4F2 exhibit altered vitamin E-{omega}-hydroxylase specific activity.
Topics: alpha-Tocopherol; Arachidonic Acid; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Gas Chromatography-Mass Spectrometry; Genetic Association Studies; Humans; Hydroxyeicosatetraenoic Acids; Hydroxylation; Kinetics; Polymorphism, Single Nucleotide; Recombinant Proteins; Substrate Specificity; Tocopherols; Tocotrienols; Vitamin E | 2010 |
Vitamin E biosynthesis: functional characterization of the monocot homogentisate geranylgeranyl transferase.
Topics: Alkyl and Aryl Transferases; Animals; Arabidopsis; Arabidopsis Proteins; Cell Line; Cold Temperature; Endosperm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hordeum; Plant Proteins; Plants, Genetically Modified; Plastids; Prenylation; Spodoptera; Substrate Specificity; Tocopherols; Tocotrienols; Triticum; Vitamin E | 2011 |
α-Tocotrienol inhibits osteoclastic bone resorption by suppressing RANKL expression and signaling and bone resorbing activity.
Topics: Animals; Bone Resorption; Cell Differentiation; Cell Survival; Cells, Cultured; Mice; Osteoclasts; RANK Ligand; Signal Transduction; Tocotrienols; Vitamin E | 2011 |
Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
Topics: Adenosine Diphosphate; alpha-Tocopherol; Animals; Blood Platelets; Collagen; Coronary Stenosis; Dogs; Hematocrit; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Thrombosis; Tocotrienols | 2011 |
Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols.
Topics: Animals; Cell Cycle; Cell Proliferation; Cells, Cultured; Chromans; Concanavalin A; Cytokines; Glutathione; Immunologic Factors; Lymphocyte Activation; Mice; NF-kappa B; T-Lymphocytes; Tocotrienols; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Vitamin E | 2011 |
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging.
Topics: Aging; Animals; Antioxidants; Benzoquinones; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Oxidative Stress; Rats; Tocotrienols; Vitamin E | 2011 |
Natural vitamin E α-tocotrienol protects against ischemic stroke by induction of multidrug resistance-associated protein 1.
Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cerebral Cortex; Male; Mice; Multidrug Resistance-Associated Proteins; Neurons; Neuroprotective Agents; Stroke; Tocotrienols; Vitamin E | 2011 |
Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia.
Topics: Animals; Antioxidants; Cell Line; Cell Survival; Chromans; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Palm Oil; Plant Oils; Tocotrienols; Vitamin E | 2011 |
Comparison of antioxidative and antifibrotic effects of α-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis.
Topics: Actins; Administration, Oral; alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hydroxyproline; Male; Malondialdehyde; Organotin Compounds; Oxidative Stress; Pancreas; Pancreatitis, Chronic; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tocotrienols; Transforming Growth Factor beta1 | 2011 |
Tissue distribution of α- and γ-tocotrienol and γ-tocopherol in rats and interference with their accumulation by α-tocopherol.
Topics: alpha-Tocopherol; Animals; Antioxidants; Carrier Proteins; Chromans; gamma-Tocopherol; Male; Rats; Rats, Wistar; Tissue Distribution; Tocotrienols; Vitamin E | 2012 |
Tocotrienols prevent hydrogen peroxide-induced axon and dendrite degeneration in cerebellar granule cells.
Topics: Animals; Autophagy; Axons; Cells, Cultured; Cerebellum; Chromans; Dendrites; Free Radical Scavengers; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Primary Cell Culture; Thiobarbituric Acid Reactive Substances; Tocotrienols; Vitamin E | 2012 |
Induction of DNA damage and caspase-independent programmed cell death by vitamin E.
Topics: Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; DNA Damage; Drug Screening Assays, Antitumor; Etoposide; Humans; Isomerism; Male; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Prostatic Neoplasms; Tocotrienols; Vitamin E | 2012 |
Alpha-tocotrienol is the most abundant tocotrienol isomer circulated in plasma and lipoproteins after postprandial tocotrienol-rich vitamin E supplementation.
Topics: Adult; Dietary Supplements; Female; Humans; Lipoproteins; Lipoproteins, HDL; Male; Palm Oil; Plant Oils; Postprandial Period; Tocopherols; Tocotrienols; Vitamin E | 2012 |
Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.
Topics: 14-alpha Demethylase Inhibitors; Administration, Oral; alpha-Tocopherol; Animals; Biological Transport; Chromans; gamma-Tocopherol; Intestine, Small; Kidney; Liver; Male; Organ Specificity; Propionates; Rats; Rats, Wistar; Tocotrienols; Vitamin E | 2011 |
Neuroprotective effect of vitamin E isoforms against chronic alcohol-induced peripheral neurotoxicity: possible involvement of oxidative-nitrodative stress.
Topics: Alcoholic Neuropathy; alpha-Tocopherol; Animals; Interleukin-1beta; Lipid Peroxidation; Male; Neuroprotective Agents; Oxidative Stress; Pain Measurement; Rats; Rats, Wistar; Sciatic Nerve; Tocotrienols; Tumor Necrosis Factor-alpha | 2012 |
Antidiabetic effects of a standardized Egyptian rice bran extract.
Topics: Animals; Blood Glucose; Chromans; Coumaric Acids; Dietary Supplements; Fatty Alcohols; Female; Glucose Tolerance Test; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Male; Oryza; Phenylpropionates; Plant Extracts; Rats; Tocotrienols; Tumor Necrosis Factor-alpha; Vitamin E | 2013 |
δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chromans; Chromatin; Humans; Microscopy, Electron, Transmission; T-Lymphocytes; Tocotrienols; Vitamin E | 2012 |
A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; CHO Cells; Cholesterol; Chromans; Cricetinae; Cricetulus; Humans; Intracellular Signaling Peptides and Proteins; Liver X Receptors; Male; Membrane Proteins; Mutant Proteins; Neoplasm Proteins; Orphan Nuclear Receptors; Prostatic Neoplasms; Recombinant Proteins; Sterol Regulatory Element Binding Protein 2; Tocotrienols; Triterpenes; Vitamin E | 2012 |
Increased α-tocotrienol content in seeds of transgenic rice overexpressing Arabidopsis γ-tocopherol methyltransferase.
Topics: Antioxidants; Arabidopsis; Gene Expression Regulation, Plant; Methyltransferases; Oryza; Plants, Genetically Modified; Protein Isoforms; Seeds; Tocopherols; Tocotrienols; Vitamin E | 2013 |
The identification of vitamin E homologues in medicinal plant samples using ESI(+)-LC-MS3.
Topics: Chromatography, High Pressure Liquid; Eucalyptus; Foeniculum; Hypericum; Melissa; Mentha; Ocimum basilicum; Plant Extracts; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Stevia; Tocotrienols; Vitamin E | 2012 |
Supervised chemical pattern recognition in almond ( Prunus dulcis ) Portuguese PDO cultivars: PCA- and LDA-based triennial study.
Topics: alpha-Tocopherol; Analysis of Variance; Discriminant Analysis; Fatty Acids; Food Analysis; Nutritive Value; Portugal; Principal Component Analysis; Prunus; Tocopherols; Tocotrienols; Triglycerides | 2012 |
Physiological effects and tissue distribution from large doses of tocotrienol in rats.
Topics: Animals; Body Weight; Diet; Dietary Supplements; Drug Administration Schedule; Male; Rats; Rats, Inbred F344; Tissue Distribution; Tocotrienols; Vitamin E | 2012 |
Comparative effects of tocotrienol-rich fraction, α-tocopherol and α-tocopheryl acetate on inflammatory mediators and nuclear factor kappa B expression in mouse peritoneal macrophages.
Topics: alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Cells, Cultured; Gene Expression; Inflammation Mediators; Macrophages; Mice; Mice, Inbred BALB C; NF-kappa B; Tocopherols; Tocotrienols | 2012 |
Genetic and biochemical basis for alternative routes of tocotrienol biosynthesis for enhanced vitamin E antioxidant production.
Topics: Alkyl and Aryl Transferases; Animals; Antioxidants; Arabidopsis; Arabidopsis Proteins; Bacterial Proteins; Cloning, Molecular; Dioxygenases; Escherichia coli; Gene Expression Regulation, Plant; Genetic Vectors; Multienzyme Complexes; Open Reading Frames; Plant Leaves; Plants, Genetically Modified; Polyisoprenyl Phosphates; Seeds; Sf9 Cells; Tocotrienols; Transformation, Genetic; Transgenes; Vitamin E | 2013 |
Stability and in vitro antiproliferative activity of bioactive "Vitamin E" fortified parenteral lipid emulsions.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Stability; Electrolytes; Emulsifying Agents; Hemolysis; Humans; Lipids; Particle Size; Poloxamer; Rabbits; Tocopherols; Tocotrienols; Vitamin E | 2013 |
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol.
Topics: Aged; Alzheimer Disease; Biomarkers; Chromans; Chromatography, High Pressure Liquid; Diagnosis, Differential; Disease Progression; Female; gamma-Tocopherol; Humans; Magnetic Resonance Imaging; Male; Prognosis; Reproducibility of Results; Severity of Illness Index; Tocotrienols; Vitamin E | 2013 |
Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Count; Cell Proliferation; Chromans; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inhibitory Concentration 50; MCF-7 Cells; NF-kappa B p50 Subunit; Paclitaxel; Palm Oil; Plant Oils; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteolysis; Reagent Kits, Diagnostic; Signal Transduction; Tocotrienols; Vitamin E | 2013 |
α-Tocopherol does not accelerate depletion of γ-tocopherol and tocotrienol or excretion of their metabolites in rats.
Topics: Administration, Oral; Adrenal Glands; alpha-Tocopherol; Animals; Cytochrome P-450 CYP4A; gamma-Tocopherol; Liver; Male; Myocardium; Rats; Rats, Wistar; Tocotrienols | 2013 |
Rice bran extract protects from mitochondrial dysfunction in guinea pig brains.
Topics: Animals; Brain; Chromans; Guinea Pigs; Male; Membrane Potential, Mitochondrial; Mitochondria; Oryza; Oxidative Stress; PC12 Cells; Plant Extracts; Rats; Tocotrienols; Vitamin E | 2013 |
Vitamin E analyses in seeds reveal a dominant presence of tocotrienols over tocopherols in the Arecaceae family.
Topics: alpha-Tocopherol; Arecaceae; Seeds; Tocotrienols; Vitamin E | 2013 |
Neuroprotective effects of α-tocotrienol on kainic acid-induced neurotoxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Hippocampus; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Tocotrienols; Vitamin E | 2013 |
Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
Topics: Age Factors; Aged; Aging; Alzheimer Disease; Biomarkers; Chi-Square Distribution; Cholesterol; Cognition; Cognitive Dysfunction; Disease Progression; Female; Finland; Humans; Incidence; Linear Models; Logistic Models; Male; Odds Ratio; Oxidative Stress; Prospective Studies; Risk Factors; Time Factors; Tocopherols; Tocotrienols; Vitamin E | 2013 |
Comparable down-regulation of TYR, TYRP1 and TYRP2 genes and inhibition of melanogenesis by tyrostat, tocotrienol-rich fraction and tocopherol in human skin melanocytes improves skin pigmentation.
Topics: Antineoplastic Agents; Antioxidants; Down-Regulation; Humans; Intramolecular Oxidoreductases; Melanins; Melanocytes; Membrane Glycoproteins; Monophenol Monooxygenase; Oxidoreductases; Skin Pigmentation; Tocopherols; Tocotrienols; Ultraviolet Rays; Vitamin E | 2014 |
Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability.
Topics: Animals; Binding Sites; Biological Availability; Carrier Proteins; Drug Design; Half-Life; Humans; Liver; Models, Molecular; Molecular Dynamics Simulation; Radiation-Protective Agents; Rats; Rats, Wistar; Tocotrienols; Vitamin E | 2014 |
Tocopherol and tocotrienol contents of different varieties of rice in Malaysia.
Topics: alpha-Tocopherol; beta-Tocopherol; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Crops, Agricultural; Food Handling; Humans; Hydrolysis; Liquid-Liquid Extraction; Malaysia; Nutritive Value; Oryza; Pigments, Biological; Reproducibility of Results; Seeds; Species Specificity; Tocopherols; Tocotrienols | 2015 |
Tocotrienol rich fraction reverses age-related deficits in spatial learning and memory in aged rats.
Topics: Aging; Animals; Antioxidants; Brain; Dietary Supplements; DNA Damage; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory; Olive Oil; Oxidative Stress; Plant Oils; Rats, Wistar; Spatial Learning; Tocotrienols; Vitamin E | 2014 |
Stability of α-tocotrienol and α-tocopherol in salami-type sausages and curing brine depending on nitrite and pH.
Topics: alpha-Tocopherol; Animals; Food Preservation; Hydrogen-Ion Concentration; Meat Products; Nitrites; Salts; Swine; Tocotrienols | 2014 |
Kinetic study of the quenching reaction of singlet oxygen by α-, β-, γ-, δ-tocotrienols, and palm oil and soybean extracts in solution.
Topics: Carotenoids; Chromans; Free Radical Scavengers; Glycine max; Kinetics; Palm Oil; Plant Extracts; Plant Oils; Singlet Oxygen; Solutions; Tocopherols; Tocotrienols; Vitamin E | 2014 |
High environmental stress yields greater tocotrienol content while changing vitamin e profiles of wild emmer wheat seeds.
Topics: alpha-Tocopherol; Chromans; Environment; gamma-Tocopherol; Intramolecular Transferases; Israel; Seeds; Stress, Physiological; Tocotrienols; Triticum; Vitamin E | 2015 |
Distribution of Tocopherols and Tocotrienols in Guinea Pig Tissues Following Parenteral Lipid Emulsion Infusion.
Topics: alpha-Tocopherol; Animals; Antioxidants; Fat Emulsions, Intravenous; Fish Oils; Guinea Pigs; Lipid Peroxidation; Olive Oil; Parenteral Nutrition; Tissue Distribution; Tocopherols; Tocotrienols | 2016 |
Tocopherol and tocotrienol analysis in raw and cooked vegetables: a validated method with emphasis on sample preparation.
Topics: Ascorbic Acid; Brassica; Chromatography, High Pressure Liquid; Cooking; Diet; Spinacia oleracea; Tocopherols; Tocotrienols; Vegetables; Vitamin E | 2015 |
The neuroprotective effects of tocotrienol rich fraction and alpha tocopherol against glutamate injury in astrocytes.
Topics: alpha-Tocopherol; Antioxidants; Astrocytes; Cell Cycle; Cell Death; Cell Line; Cell Survival; Glutamic Acid; Humans; Lipid Peroxidation; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Neuroprotective Agents; Thiobarbituric Acid Reactive Substances; Tocotrienols | 2014 |
Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 8; Cell Cycle; Cell Line, Tumor; Cell Survival; Central Nervous System Neoplasms; Chromans; Cytochromes c; DNA Fragmentation; Glioblastoma; Humans; Isomerism; Lung Neoplasms; Mitochondria; Tocotrienols; Vitamin E | 2014 |
Supplementation of laying-hen feed with annatto tocotrienols and impact of α-tocopherol on tocotrienol transfer to egg yolk.
Topics: alpha-Tocopherol; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bixaceae; Carotenoids; Chickens; Dietary Supplements; Egg Yolk; Female; Plant Extracts; Tocotrienols | 2015 |
Control of macaw palm seed germination by the gibberellin/abscisic acid balance.
Topics: Abscisic Acid; alpha-Tocopherol; Arecaceae; Cyclopentanes; Cytokinins; Germination; Gibberellins; Lipid Peroxidation; Oxylipins; Plant Growth Regulators; Seeds; Tocotrienols | 2015 |
Gamma-tocotrienol treatment increased peroxiredoxin-4 expression in HepG2 liver cancer cell line.
Topics: Antineoplastic Agents; Antioxidants; Bile Duct Neoplasms; Chromans; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Hep G2 Cells; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Peroxiredoxins; Proteins; Proteomics; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tocotrienols; Up-Regulation; Vitamin E; Vitamins | 2015 |
Tocotrienol-rich fraction prevents cellular aging by modulating cell proliferation signaling pathways.
Topics: Antioxidants; Cell Proliferation; Cells, Cultured; Cellular Senescence; Diploidy; Fibroblasts; Humans; Tocotrienols; Vitamin E | 2015 |
Antioxidant capacity and vitamin E in barley: Effect of genotype and storage.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Food Storage; Genotype; Hordeum; Tocotrienols; Vitamin E | 2015 |
Changes in lipid substances in rice during grain development.
Topics: Chromans; Edible Grain; Lipid Metabolism; Oryza; Phenylpropionates; Seeds; Tocopherols; Tocotrienols; Vitamin E | 2015 |
Tocotrienol Rich Palm Oil Extract Is More Effective Than Pure Tocotrienols at Improving Endothelium-Dependent Relaxation in the Presence of Oxidative Stress.
Topics: Acetylcholine; alpha-Tocopherol; Animals; Aorta; Endothelium, Vascular; Free Radical Scavengers; In Vitro Techniques; Male; Nitroprusside; Oxidative Stress; Palm Oil; Plant Extracts; Plant Oils; Pyrogallol; Rats, Wistar; Superoxides; Tocotrienols; Vasodilation; Xanthine Oxidase | 2015 |
Cytoprotective Effect of Tocotrienol-Rich Fraction and α-Tocopherol Vitamin E Isoforms Against Glutamate-Induced Cell Death in Neuronal Cells.
Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Free Radicals; Glutamic Acid; Humans; Malondialdehyde; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Neuroblastoma; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Tocotrienols | 2014 |
Tocopherols and tocotrienols in serum and liver of dairy cows receiving conjugated linoleic acids or a control fat supplement during early lactation.
Topics: Animals; Carrier Proteins; Cattle; Diet; Dietary Supplements; Female; Gene Expression; Lactation; Linoleic Acids, Conjugated; Liver; Milk; Pregnancy; RNA, Messenger; Tocopherols; Tocotrienols; Vitamin E | 2015 |
Enhanced tocopherol levels during early germination events in Chamaerops humilis var. humilis seeds.
Topics: Antioxidants; Arecaceae; Germination; Lipid Peroxidation; Malondialdehyde; Molecular Structure; Seeds; Tocopherols; Tocotrienols; Vitamin E; Water | 2015 |
HPLC Separation of Vitamin E and Its Oxidation Products and Effects of Oxidized Tocotrienols on the Viability of MCF-7 Breast Cancer Cells in Vitro.
Topics: Breast Neoplasms; Cell Division; Cell Survival; Chromatography, High Pressure Liquid; Female; Humans; MCF-7 Cells; Oxidation-Reduction; Tocotrienols; Vitamin E | 2015 |
Anti-inflammatory γ- and δ-tocotrienols improve cardiovascular, liver and metabolic function in diet-induced obese rats.
Topics: Adipose Tissue; alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Body Composition; Cardiovascular System; Diet, High-Fat; Dietary Carbohydrates; Fatty Liver; Insulin Resistance; Liver; Male; Metabolic Syndrome; Obesity, Abdominal; Organ Size; Rats; Rats, Wistar; Tocotrienols; Vitamin E | 2017 |
Vitamin E analysis by ultra-performance convergence chromatography and structural elucidation of novel α-tocodienol by high-resolution mass spectrometry.
Topics: alpha-Tocopherol; Chromans; Chromatography, High Pressure Liquid; Mass Spectrometry; Palm Oil; Plant Oils; Tocotrienols; Vitamin E | 2016 |
Genotypic variation in phenolic acids, vitamin E and fatty acids in whole grain rice.
Topics: alpha-Tocopherol; Coumaric Acids; Fatty Acids; Hydroxybenzoates; Oryza; Phenols; Tocopherols; Tocotrienols; Vitamin E; Whole Grains | 2016 |
Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat3.
Topics: Antineoplastic Agents; Apoptosis; Bixaceae; Carotenoids; Cell Cycle; Cell Line, Tumor; Genes, src; Humans; Male; Plant Extracts; Prostatic Neoplasms; STAT3 Transcription Factor; Tocotrienols; Vitamin E; Vitamins | 2015 |
The Tocotrienol-Rich Fraction Is Superior to Tocopherol in Promoting Myogenic Differentiation in the Prevention of Replicative Senescence of Myoblasts.
Topics: Adolescent; beta-Galactosidase; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cell Shape; Cell Survival; Cellular Senescence; Desmin; Female; Free Radicals; Humans; Male; Muscle Development; Myoblasts; Myogenic Regulatory Factors; Phenotype; RNA, Messenger; Tocopherols; Tocotrienols; Vitamin E | 2016 |
Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis.
Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Hydroxycholesterols; Lipids; Microscopy, Fluorescence; Neurons; Reactive Oxygen Species; Tocotrienols; Tretinoin; Vitamin E | 2017 |
The Vitamin E Analog Gamma-Tocotrienol (GT3) Suppresses Radiation-Induced Cytogenetic Damage.
Topics: Animals; Antioxidants; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA Repair; DNA Repair Enzymes; Female; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Radiation Injuries; Radiation, Ionizing; Tocotrienols; Vitamin E | 2016 |
α-Tocopherol Attenuates the Triglyceride- and Cholesterol-Lowering Effects of Rice Bran Tocotrienol in Rats Fed a Western Diet.
Topics: Adipose Tissue; alpha-Tocopherol; Animals; Carnitine O-Palmitoyltransferase; Cholesterol; Diet, Western; Dyslipidemias; Humans; Liver; Male; Oryza; Plant Extracts; Rats; Rats, Inbred F344; Tocotrienols; Triglycerides | 2016 |
Tocotrienol Affects Oxidative Stress, Cholesterol Homeostasis and the Amyloidogenic Pathway in Neuroblastoma Cells: Consequences for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Antioxidants; Cell Line; Cholesterol; Gene Expression Regulation, Enzymologic; Humans; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Tocotrienols; Vitamin E | 2016 |
Synthesis, characterization, and in-vitro antitumor activity of the polyethylene glycol (350 and 1000) succinate derivatives of the tocopherol and tocotrienol isomers of Vitamin E.
Topics: alpha-Tocopherol; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Isomerism; MCF-7 Cells; Micelles; Polyethylene Glycols; Succinic Acid; Tocotrienols; Vitamin E | 2017 |
High-Dietary Alpha-Tocopherol or Mixed Tocotrienols Have No Effect on Bone Mass, Density, or Turnover in Male Rats During Skeletal Maturation.
Topics: alpha-Tocopherol; Animals; Bone Density; Dietary Supplements; Femur; Humans; Liver; Male; Osteocalcin; Osteoporosis; Rats; Rats, Sprague-Dawley; Tibia; Tocotrienols | 2017 |
Semi-preparative HPLC purification of δ-tocotrienol (δ-T3) from Elaeis guineensis Jacq. and Bixa orellana L. and evaluation of its in vitro anticancer activity in human A375 melanoma cells.
Topics: Antineoplastic Agents, Phytogenic; Arecaceae; Bixaceae; Cell Line, Tumor; Chromatography, High Pressure Liquid; Fruit; Humans; Melanoma; Seeds; Tocotrienols; Vitamin E | 2018 |
Effect of processing on composition changes of selected spices.
Topics: alpha-Tocopherol; beta Carotene; Chromatography, Gas; Chromatography, High Pressure Liquid; Cooking; Fatty Acids; Hot Temperature; Microwaves; Spices; Tocotrienols; Water | 2017 |
Gemcitabine-vitamin E conjugates: Synthesis, characterization, entrapment into nanoemulsions, and in-vitro deamination and antitumor activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromans; Deamination; Deoxycytidine; Gemcitabine; Humans; Nanoparticles; Tocotrienols; Vitamin E | 2017 |
High purity tocotrienols attenuate atherosclerotic lesion formation in apoE-KO mice.
Topics: Animals; Apolipoproteins E; Blood Glucose; Body Weight; Diet, High-Fat; Gene Expression Regulation; Lipids; Liver; Male; Mice, Knockout; Plaque, Atherosclerotic; Sucrose; Tocotrienols; Vitamin E | 2017 |
Tocotrienols Stimulate Insulin Secretion of Rat Pancreatic Isolated Islets in a Dynamic Culture.
Topics: Animals; Antioxidants; Chromans; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Chloride; Rats; Rats, Wistar; Tissue Culture Techniques; Tocotrienols; Vitamin E | 2017 |
The Effect of Pressure and Solvent on the Supercritical Fluid Chromatography Separation of Tocol Analogs in Palm Oil.
Topics: alpha-Tocopherol; Chromans; Chromatography, Supercritical Fluid; Molecular Structure; Palm Oil; Pressure; Solvents; Tocopherols; Tocotrienols; Vitamin E | 2017 |
Novel Loci Underlie Natural Variation in Vitamin E Levels in Maize Grain.
Topics: Chlorophyll; Genome-Wide Association Study; Quantitative Trait Loci; Tocopherols; Tocotrienols; Vitamin E; Zea mays | 2017 |
WRINKLED1 and ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE1 regulate tocochromanol metabolism in Arabidopsis.
Topics: Acyl Coenzyme A; Alkyl and Aryl Transferases; Arabidopsis; Arabidopsis Proteins; Biosynthetic Pathways; Chromans; Diacylglycerol O-Acyltransferase; Diglycerides; Intramolecular Transferases; Lipid Metabolism; Seeds; Tocopherols; Tocotrienols; Transcription Factors; Vitamin E | 2018 |
Development and in-vitro characterization of nanoemulsions loaded with paclitaxel/γ-tocotrienol lipid conjugates.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Emulsions; Humans; Lipids; Nanoparticles; Paclitaxel; Polyethylene Glycols; Tocotrienols; Vitamin E | 2018 |
Proteasome inhibitors modulate anticancer and anti-proliferative properties via NF-kB signaling, and ubiquitin-proteasome pathways in cancer cell lines of different organs.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Line, Tumor; Cell Survival; Cells, Cultured; Estradiol; Hepatitis C; Humans; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Quercetin; Signal Transduction; Tocotrienols; Vitamin E | 2018 |
Cellular Uptake and Bioavailability of Tocotrienol-Rich Fraction in SIRT1-Inhibited Human Diploid Fibroblasts.
Topics: Biological Availability; Cellular Senescence; Diploidy; Fibroblasts; Humans; Isomerism; Lipid Metabolism; Sirtuin 1; Time Factors; Tocopherols; Tocotrienols; Vitamin E | 2018 |
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol.
Topics: alpha-Tocopherol; Animals; Apoptosis; Dose-Response Relationship, Drug; Fatty Acids; Fibroblasts; Humans; Ketocholesterols; Male; Membrane Potential, Mitochondrial; Membrane Proteins; Mice; Mitochondria; Oligodendroglia; Peroxisomes; Plasmalogens; Tocotrienols; Zellweger Syndrome | 2018 |
α-Tocopherol transfer protein does not regulate the cellular uptake and intracellular distribution of α- and γ-tocopherols and -tocotrienols in cultured liver cells.
Topics: alpha-Tocopherol; Biological Transport; Carrier Proteins; Cell Membrane; Endoplasmic Reticulum; gamma-Tocopherol; Hep G2 Cells; Hepatocytes; Humans; Lysosomes; Tocotrienols | 2018 |
Transcriptional Regulation of Vitamin E Biosynthesis during Germination of Dwarf Fan Palm Seeds.
Topics: Amino Acid Sequence; Arecaceae; Biosynthetic Pathways; Cyclopentanes; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Germination; Hydrogen Peroxide; Oxylipins; Phylogeny; Plant Growth Regulators; Plant Proteins; Seeds; Tocopherols; Tocotrienols; Transcription, Genetic; Vitamin E | 2018 |
Optimization of process parameters in preparation of tocotrienol-rich red palm oil-based nanoemulsion stabilized by Tween80-Span 80 using response surface methodology.
Topics: Carotenoids; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Emulsions; Hexoses; Lipid Droplets; Nanostructures; Palm Oil; Particle Size; Polysorbates; Pressure; Surface-Active Agents; Tocotrienols; Vitamin E; Water | 2018 |
Content of Selected Vitamins and Antioxidants in Colored and Nonpigmented Varieties of Quinoa, Barley, and Wheat Grains.
Topics: alpha-Tocopherol; Antioxidants; Chenopodium quinoa; Crops, Agricultural; Hordeum; Humans; Nutritive Value; Seeds; Thiamine; Tocopherols; Tocotrienols; Triticum; Vitamin A; Vitamin E; Vitamins | 2018 |
Effects of antibiotics on degradation and bioavailability of different vitamin E forms in mice.
Topics: Animals; Anti-Bacterial Agents; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Tocopherols; Tocotrienols; Vitamin E | 2019 |
Suppression of colorectal cancer cell growth by combined treatment of 6-gingerol and γ-tocotrienol via alteration of multiple signalling pathways.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechols; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromans; Colorectal Neoplasms; DNA Repair; Fatty Alcohols; Forkhead Box Protein M1; Gene Expression Profiling; Humans; Signal Transduction; Tocotrienols; Vitamin E; Wnt Signaling Pathway | 2019 |
Less widespread plant oils as a good source of vitamin E.
Topics: Antioxidants; Chromatography, High Pressure Liquid; gamma-Tocopherol; Plant Oils; Rubus; Tocotrienols; Vitamin E | 2019 |
Effect of Accelerated Storage on Fatty Acids, Thermal Properties and Bioactive Compounds of Kenaf Seed Oil.
Topics: Fatty Acids; Food Storage; Hibiscus; Hot Temperature; Linoleic Acid; Oxidation-Reduction; Plant Oils; Seeds; Tocopherols; Tocotrienols; Triglycerides; Vitamin E | 2019 |
Protective Effect of Tocotrienol on In Vitro and In Vivo Models of Parkinson's Disease.
Topics: Animals; Cytoprotection; Disease Models, Animal; Humans; Mice; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Tocotrienols; Vitamin E | 2019 |
Investigation of the curative effects of palm vitamin E tocotrienols on autoimmune arthritis disease in vivo.
Topics: Administration, Oral; Animals; Arthritis, Experimental; C-Reactive Protein; Cytokines; Disease Models, Animal; Female; Palm Oil; Rats; Tocotrienols; Treatment Outcome; Vitamin E | 2019 |
Functional dissection of HGGT and HPT in barley vitamin E biosynthesis via CRISPR/Cas9-enabled genome editing.
Topics: CRISPR-Cas Systems; Gene Editing; Hordeum; Humans; Tocopherols; Tocotrienols; Vitamin E | 2020 |
Tocotrienols Influence Body Weight Gain and Brain Protein Expression in Long-Term High-Fat Diet-Treated Mice.
Topics: Animals; Antioxidants; Body Weight; Cardiovascular Diseases; Cognition; Cognitive Dysfunction; Diabetes Mellitus; Diet, High-Fat; Hypertension; Male; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Tocopherols; Tocotrienols; Vitamin E; Weight Gain | 2020 |
Inhibition mechanism of 3-hydroxy-3-methyl-glutaryl-CoA reductase by tocotrienol-rich rice bran fraction optimally extracted with ultrasonic energy.
Topics: Binding Sites; Cholesterol; Chromatography, High Pressure Liquid; Dietary Fiber; Fatty Acids, Nonesterified; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Imaging, Three-Dimensional; Inhibitory Concentration 50; Kinetics; Ligands; Molecular Conformation; Molecular Docking Simulation; Oryza; Oxidoreductases; Peroxides; Protein Binding; Solvents; Sonication; Tocotrienols; Ultrasonics; Vitamin E | 2020 |
Cellular uptake and anti-inflammatory effects of palm oil-derived delta (δ)-tocotrienol in microglia.
Topics: Animals; Anti-Infective Agents; Antioxidants; Mice; Mice, Inbred C57BL; Microglia; Nitric Oxide; Nitric Oxide Synthase Type II; Palm Oil; Primary Cell Culture; Tocotrienols; Tumor Necrosis Factor-alpha; Vitamin E | 2020 |
Analysis of expression of vitamin E-binding proteins in H2O2 induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction.
Topics: alpha-Tocopherol; Antioxidants; Biological Availability; Biological Transport; Carrier Proteins; Cell Line, Tumor; Dietary Supplements; Humans; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Oxidative Stress; Tocotrienols; Vitamin E | 2020 |
[Eight vitamin E congeners in seafood and aquatic products in Zhejiang Province].
Topics: Animals; China; Female; Male; Seafood; Tocopherols; Tocotrienols; Vitamin E | 2020 |
Application of Partial Hydrogenation for the Generation of Minor Tocochromanol Homologs and Functional Evaluation of Hydrogenated Tocotrienol-rich Vitamin E Oil in Diabetic Obese Mice.
Topics: Animals; Cholesterol, HDL; Diabetes Mellitus; Glucose; Hydrogenation; Hyperglycemia; Lipid Metabolism; Male; Mice, Inbred Strains; Obesity; Structure-Activity Relationship; Time Factors; Tocotrienols; Vitamin E | 2021 |
[Determination of eight vitamin E in vegetable oils by gas chromatography-mass spectrometry and its application on authentication of sesame oil].
Topics: Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Plant Oils; Sesame Oil; Tocotrienols; Vitamin E | 2020 |
Role of Vitamin E in Selected Malignant Neoplasms in Women.
Topics: Antioxidants; Female; Humans; Male; Neoplasms; Tocopherols; Tocotrienols; Vitamin E | 2022 |
Fruit tree leaves as valuable new source of tocopherol and tocotrienol compounds.
Topics: Fruit; Tocopherols; Tocotrienols; Trees; Vitamin E | 2022 |
Different forms of vitamin E and metabolite 13'-carboxychromanols inhibit cyclooxygenase-1 and its catalyzed thromboxane in platelets, and tocotrienols and 13'-carboxychromanols are competitive inhibitors of 5-lipoxygenase.
Topics: A549 Cells; Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Fatty Acids; Humans; Lipoxygenase Inhibitors; Mice; RAW 264.7 Cells; Thromboxanes; Tocopherols; Tocotrienols; Vitamin E; Vitamins | 2022 |
Vitamin E research: Past, now and future.
Topics: Antioxidants; Signal Transduction; Tocopherols; Tocotrienols; Vitamin E | 2021 |
Metabolism of natural forms of vitamin E and biological actions of vitamin E metabolites.
Topics: alpha-Tocopherol; Animals; Mice; Neoplasms; Tocopherols; Tocotrienols; Vitamin E | 2022 |
Effects of Vitamin E and Dietary Conditions on the Differentiation and Maturation of Osteoclast.
Topics: Animals; Cell Differentiation; Diet; Mice; Osteoclasts; RANK Ligand; Tocotrienols; Vitamin E | 2022 |
Supercritical fluid chromatography with post-column addition of supporting electrolyte solution for electrochemical determination of tocopherol and tocotrienol isomers.
Topics: Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Electrolytes; Methanol; Tocopherols; Tocotrienols; Vitamin E | 2022 |
Transcriptomic Analysis of the Anticancer Effects of Annatto Tocotrienol, Delta-Tocotrienol and Gamma-Tocotrienol on Chondrosarcoma Cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Chondrosarcoma; Humans; Tocotrienols; Transcriptome; Vitamin E | 2022 |
Tocotrienol-Rich Fraction and Levodopa Regulate Proteins Involved in Parkinson's Disease-Associated Pathways in Differentiated Neuroblastoma Cells: Insights from Quantitative Proteomic Analysis.
Topics: Chromatography, Liquid; Humans; Levodopa; Neuroblastoma; Parkinson Disease; Proteomics; Tandem Mass Spectrometry; Tocotrienols; Vitamin E | 2022 |
Suppression of Amyloid-β Adsorption on Endoplasmic Reticulum Stress-Mimicking Membranes by α-Tocopherol and α-Tocotrienol.
Topics: Adsorption; alpha-Tocopherol; Alzheimer Disease; Amyloid beta-Peptides; Endoplasmic Reticulum Stress; Humans; Tocotrienols; Vitamin E | 2022 |
γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway.
Topics: Apoptosis; Cell Line, Tumor; Humans; Signal Transduction; Stomach Neoplasms; Tocotrienols; Vitamin E | 2023 |
The difference in the cellular uptake of tocopherol and tocotrienol is influenced by their affinities to albumin.
Topics: Albumins; Molecular Docking Simulation; Serum Albumin, Bovine; Tocopherols; Tocotrienols; Vitamin E | 2023 |
Efficient Secretory Production of δ-Tocotrienol by Combining Pathway Modularization and Transportation Engineering.
Topics: Cholesterol; Tocotrienols; Vitamin E | 2023 |
Effect of nano-delivery systems on the bioavailability and tissue biodistribution of vitamin E tocotrienols.
Topics: Animals; Biological Availability; Humans; Nanoparticle Drug Delivery System; Rats; Tissue Distribution; Tocotrienols; Vitamin E | 2023 |
Association between Vitamin A and E Forms and Prostate Cancer Risk in the Singapore Prostate Cancer Study.
Topics: alpha-Tocopherol; beta Carotene; Beta-Cryptoxanthin; Case-Control Studies; Humans; Lutein; Male; Prostatic Neoplasms; Singapore; Tocotrienols; Ubiquinone; Vitamin A | 2023 |
Simultaneous Determination of Vitamin E and γ-Oryzanol in Rice Bran Oil via HPSEC-PDA without Sample Pretreatment.
Topics: Chromatography, Gel; Rice Bran Oil; Tocopherols; Tocotrienols; Vitamin E | 2023 |
Vitamin E biofortification: Maximizing oilseed tocotrienol and total vitamin E tocochromanol production by use of metabolic bypass combinations.
Topics: Arabidopsis; Arabidopsis Proteins; Biofortification; Dioxygenases; Tocotrienols; Vitamin E | 2023 |
A new RPLC-ESI-MS method for the determination of eight vitamers of vitamin E.
Topics: Brassicaceae; Flax; Tandem Mass Spectrometry; Tocotrienols; Vitamin E | 2024 |
Dietary Vitamin E Isoforms Intake: Development of a New Tool to Assess Tocopherols and Tocotrienols Intake in Adults.
Topics: Adult; alpha-Tocopherol; Diet; Humans; Protein Isoforms; Tocopherols; Tocotrienols; Vitamin E | 2023 |
Optimization of high-efficient pre-column sample treatments and C18-UFLC method for selective quantification of selected chemical forms of tocopherol and tocotrienol in diverse foods.
Topics: alpha-Tocopherol; Animals; Cholesterol; Chromatography, High Pressure Liquid; Food; Tocopherols; Tocotrienols | 2024 |